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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Pembelajaran dan Biologi Nukleus Science Midwifery Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Farmanesia Jurnal ABDIMAS MUTIARA
Yosy Cinthya Eriwaty Silalahi
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Veterinary Other

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UJI AKTIVITAS EKSTRAK ETANOL DAUN SAWO MANILA (Manikara zapota L.) TERHADAP BAKTERI Bacillus cereus Manurung, Kesaktian; Adiansyah, Adiansyah; Silalahi, Yosy Cinthya Eriwaty; Hayati, Sry
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Sawo manila (Manikara zapota L.) merupakan salah satu bahan alam sebagai obat alternatif yang telah banyak dimanfaatkan oleh masyarakatnya juga untuk mengobati berbagai penyakit dan sawo merupakan tanaman dari family Sapotaceae yang digunakan dalam pengobatan tradisional. Ekstrak daun sawo manila mengandung alkaloid, tanin, flavonoid, dan saponin yang diketahui memiliki aktivitas antibakteri. Tujuan penulisan surat ini adalah untuk mengetahui aktivitas antibakteri sawo manila (Manikara zapota L.) terhadap bakteri Bacillus cereus. Penelitian ini menggunakan metode eksperimen, dengan metode ekstraksi maserasi dan metode chakra difusi untuk aktivitas antibakteri. Hasil penelitian menunjukkan bahwa simplisia memiliki kadar air 9,30%, larut dalam air 23,72%, kadar larut air ekstrak 31,15%, kadar abu total 1,11%, dan kadar ask tidak larut asam. 0,30%. Percobaan aktivitas anti bakteri ekstrak etanol daun sawo terhadap daya hambat bakteri bacillus cereus pada konsentrasi 20%, 40%, 60%, 80% dan 100% yaitu 12,62 mm, 15,0 mm, 15,74 mm, 16,9 mm , dan 18,78 mm, control positif menggunakan kotrimoksazol dan luas zona hambat 21,5 mm daun sawo manila dapat menghambat Bacillus cereus.
PEMERIKSAAN ZAT WARNA MERAH PADA MINUMAN BOTOL YANG BEREDAR DI SEKITAR JALAN KAPTEN MUSLIM MEDAN SECARA KROMATOGRAFI KERTAS Silalahi, Yosy Cinthya Eriwaty; Wiratma, Dicky Yuswardi; Sianipar, Artha Yuliana
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i2.2737

Abstract

Drinks are materials that are needed by living things, which are useful for survival. Therefore, many manufacturers are innovating with drinks, one of which is bottled drinks and adding colorants to drinks to attract buyers. The purpose of this study was to determine whether or not the use of red dye is not allowed in bottled drinks sold around Jalan Captain Muslim Medan. This study uses a descriptive method, namely by conducting examinations in the laboratory. Drinks that are red were taken as samples, namely as many as 5 samples. Samples were purified using wool absorption, followed by identification using paper chromatography compared with tables. The results of the observations showed that from the 5 samples tested, none of the bottled drinks containing red dye were prohibited.
FORMULASI KRIM ANTI-AGING DARI EKSTRAK KULIT BUAH JERUK LEMON (Citruslimon) Silalahi, Yosy Cinthya Eriwaty; Sinaga, Eka Margaret; Thaib, Cut Masyithah
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Anti-aging is a preparation that is useful for preventing or slowing down the effects of aging such as wrinkles, dark spots, rough skin, and enlarged pores. Lemon peel contains flavonoids, namely hesperidin which can prevent aging and can improve skin health. This study aims to formulate anti-aging cream preparations, test the anti-aging effect, and determine the best concentration of anti-aging cream from lemon peel extract. The concentration of lemon peel extract used as a cream ingredient are: 2.5%, 5%, 7.5%, 10%. The tests carried out were homogeneity test, determination of emulsion type, pH, stability observation, skin irritation test. The test was carried out for 4 weeks. The results showed that the anti-aging cream preparations produced were homogeneous and showed an o/w type. The pH test when the cream was made was: 6-7 and after 12 weeks of storage, it was: 5-7. Anti-aging cream preparations have shown a significant increase in skin effects after 1 week, 2 weeks, 3 weeks, and 4 weeks. F5 (10% cream) provides the best anti-aging effectiveness. Lemon peel extract can be formulated into an o/a cream preparation that is able to provide anti-aging effects on the skin. Formula 5 (F5) with a concentration of 10% lemon peel extract was the most.
PENGGUNAAN PATI KENTANG (Solanum tuberosum) LOKAL PREGELATINASI SEBAGAI BAHAN PENGEMBANG PADA TABLET PARASETAMOL GRANUL SECARA KEMPA LANGSUNG Dalimunthe, Agusmal; Thaib, Cut Masyithah; Silalahi, Yosy Cinthya Eriwaty; Tarigan, Mira Eka Diana Br
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Potatoes have a high nutritional content such as carbohydrates, starch, fat, protein, and water. Almost 90% of medicinal raw materials, both active substances and additives are obtained through imports and abroad, even though Indonesia's natural resources can be developed. This study aims to determine the effect of using pregelatinized local potato starch (Solanum tuberosum) as a developer in paracetamol tablets by direct compression. This research was conducted experimentally using five formulas with certain concentrations of F1 (4%), F2 (6%), F3 (8%), and F4 (10%). Then the tablet evaluation test was carried out, namely the weight uniformity test, tablet hardness test, tablet friability test, tablet disintegration time test. The results showed that the paracetamol tablets with local pregelatinized potato starch developer were made to meet the requirements for weight uniformity test, tablet hardness test, tablet friability test, and tablet disintegration time test. It can be concluded that local pregelatinized potato starch (Solanum tuberosum) can be used as a developer in paracetamol tablets.
ANALISIS TIMBAL (Pb) DAN KADMIUM (Cd) PADA KERANG BULUYANG DIPEROLEH DARI PASAR SEI SIKAMBING MEDAN SECARA KUALITATIF Maimunah, Siti; Sianipar, Artha Yuliana; Zuhairiah, Zuhairiah; Silalahi, Yosy Cinthya Eriwaty
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2748

Abstract

Shellfish (Anadaraantiquata) is one type of shellfish that has the potential to be used as a food source in fulfilling the nutrition of the Indonesian people. Feather clams (Anadaraantiquata) belong to the class Bivalvia which are edible and have economic value. The purpose of this study was to determine the content of lead and cadmium in feather shells. Samples were taken from two fur shell traders at the Sei Sikambing market in Medan using a random sampling method with qualitative testing using disodium sulfide, potassium iodide, potassium chromate, potassium cyanide, and sodium hydroxide reagents, in accordance with work procedures. used in the Medan Regional Health Laboratory. The results showed that of the two samples tested, both samples did not contain lead (Pb) and cadmium (Cd). Keywords: Feather shells, lead (Pb), Cadmium (Cd), Qualitative.
ANALISA KADAR CEMARAN MERKURI (Hg) PADA IKAN TUNA (Thunnus sp.) KEMASAN KALENG SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Adiansyah, Adiansyah; Silalahi, Yosy Cinthya Eriwaty; Ritonga, Ahmad Hafizullah
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2750

Abstract

Mercury is a heavy metal that can have a toxic effect on the body so that it can cause death. Mercury metal contamination in food is regulated in SNI number 7387 of 2009 regarding the Maximum Heavy Metal Limit. Some metal waste disposal ends up in river, lake, or sea waters so that metal pollution can occur in the ecosystem. This study aims to determine the levels of mercury metal contamination in canned tuna. Sample preparation was carried out using the wet digestion method with a microwave digestion device. The results of the analysis showed that from the six samples of canned tuna fish according to the maximum limit and meet the standard maximum limit of 1.0 mg/kg SNI. Mercury analysis was carried out using the AAS (Atomic Absorption Spectrophotometry) method. The wavelength used is at 253.7 nm. The results showed that the mercury in tuna brand A was 0.9030±0 mg/kg tuna brand B 0.1029±0 mg/kg, tuna brand C 0.4524±0 mg/kg, tuna brand C D 0.0967±0 mg/kg, tuna brand E 0.9567 ± 0 mg/kg, and tuna brand F 0.8034±0 mg/kg.
ANALISIS KADAR PROTEIN PADA ASI DAN SUSU FORMULA UNTUK USIA 0-6 BULAN Zuhairiah, Zuhairiah; Silalahi, Yosy Cinthya Eriwaty; Nurbaya, Siti
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2756

Abstract

Breast milk has advantages compared to other milk, including guaranteed clean liness, the temperature of breast milk is the same as body temperature, rich in food essences that accelerate the growth of brain cells and the development of the nervous system. This study aims to determine the protein content in breast milk and infant formula and to determine the difference in higher protein between breast milk and infant formula. The samples used in this study were breast milk for 1 week, breast milk for 3 months, formula A, formula B and formula C. The results of this study obtained measurements made that maximum absorption was obtained at a wavelength of 542.00 nm, Samples of breast milk were 1 week. and breast milk for 3 months which showed a significant difference in protein content. Sample A, Sample B, and sample C milk had lower protein content than Sample 1 week breast milk and 3-month breast milk. The conclusion of this study is that there are a certain amount of protein in breast milk and infant formula, namely 2.77±0.0276 g/100 g in 3-month breast milk, 2.26±0.0126 g/100g in 1 week breast milk, 1 ,37±0.0308 g/100g in formula milk sample A 1.36±0.0247 g/100g milk formula B and 1.44±0.0728 g/100 g in formula C and There is a significant difference in protein content. significant in breast milk, infant formula for samples A, B and C.
PENETAPAN ANGKA KAPANG KHAMIR (AKK) PADA REMPAH-REMPAH YANG DIJUAL DI PASAR SRI GUNTING MEDAN Maimunah, Siti; Harefa, Karnerius; Silalahi, Yosy Cinthya Eriwaty; Manurung, Kesaktian
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2761

Abstract

Spices containing fungal contamination exceed the stipulated limit of 1x104 colonies/g which will affect the stability of the preparation and aflatoxins that are harmful to health such as liver cancer. This study aims to determine the value of the yeast mold number (AKK) in spices at the Sri Gunting market, Medan. The population in this study were spices in the form of wet powder, namely turmeric (Curcuma longa Linn.), ginger (Zingiber officinale Rosc.), and temulawak (Curcuma xanthorhiza Roxb.), and 250 grams of each ingredient was taken from four spice traders. with location criteria such as on the edge of a highway, near a ditch/gully, inside a kiosk, and near a meat seller as a sample. Subjects of research and observations are presented in the form of tables and figures which are then analyzed descriptively. The results of the study found that the AKK of spices sold at the Sri Gunting market in Medan was equal to trader A (turmeric 16.1x10^4, Ginger 7.9x10^4, Temulawak 11.1x10^4cfu/g), trader B (turmeric > 150, Ginger 11.5x10^4Temulawak 18x10^4cfu/g), merchant C (turmeric 12.2x10^4, Ginger 6.1x10^4, Temulawak 4.5x10^4cfu/g), and merchant D (turmeric >150, Ginger 10.9x10^4, Temulawak >150cfu/g) which means that the AKK contained from spices sold at the Sri Gunting market in Medan does not meet the requirements according to the Food and Drug Supervisory Agency (BPOM).
UJI PENINGKATAN KADAR ASAM AMINO PADA TAPE KETAN HITAM DENGAN PENAMBAHAN SARI BUAH NANAS DENGAN METODE SPEKTROFOTOMETRI SINAR TAMPAK Supartiningsih, Supartiningsih; Maimunah, Siti; Silalahi, Yosy Cinthya Eriwaty
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2764

Abstract

Amino acid levels in sticky rice tape are still relatively low, while amino acids themselves are food substances for body growth. Pineapple contains the enzyme bromelain. This enzyme is one of the protease enzymes that can hydrolyze protein, therefore it can increase amino acid levels. This study aims to determine the increase in amino acid levels in black sticky rice tape with the addition of pineapple juice and to determine the effect of adding pineapple juice to amino acid levels in black sticky rice tape. In the process of making black sticky rice tape, 25 ml 50 ml of pineapple juice was added per 500 grams each, while one treatment did not add pineapple juice as a control. Black glutinous rice that has been fermented for 2-3 days was tested for increased levels of amino acids by using visible light spectrophotometry. The sample of black glutinous tape without the addition of pineapple juice obtained an average content of 4.73%, on the sample of black glutinous tape with the addition of 25 ml of pineapple juice the average content obtained was 6.50%, and the sample of black sticky rice tape with the addition of 50 ml pineapple juice the average level obtained was 7.76% and gave the effect of increasing amino acid levels on black sticky rice tape.
IDENTIFIKASI MERKURI PADA BEBERAPA KRIM WAJAH YANG TERDAPAT DI PASAR BINJAI Zuhairiah, Zuhairiah; Nurbaya, Siti; Silalahi, Yosy Cinthya Eriwaty
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2765

Abstract

Cosmetics are used to whiten the skin and also to avoid skin disorders both from inside and outside, such as blemishes, spots, freckles. The addition of mercury to cosmetics causes dark spots, allergies, irritation, and high doses can cause brain and kidney damage. Mercury is a substance that is prohibited by the Regulation of the Head of the Food and Drug Supervisory Agency (BPOM) of the Republic of Indonesia No. HK.00.05.42.1018 concerning cosmetics. The purpose of this study was to determine whether there was a mercury compound in facial whitening cream. The cream was taken at random from a whitening cream vendor in the Binjai market. Mercury identification was carried out at the Medan Regional Health Laboratory and from the results of research on 5 samples of facial whitening cream, it turned out that there was one sample containing mercury compounds, namely sample B, which did not meet the requirements.
Co-Authors Adiansyah Adiansyah, Adiansyah Asmaradhani, Dian Dalimunthe, Agusmal Dicky Yuswardi Wiratma Eka Margareta Sinaga Ginting, Nahitma Harefa, Karnerius Hayati, Sry Hutabarat, Vitrilina Jansen Silalahi Khairunnisa Khairunnisa Manurung, Kesaktian Marpaung, Jon Kenedy Nasution, Dinda Juita Nasution, Khairina Nurussakinah, Nurussakinah PUJI LESTARI Purba, Trionaldo Purwandari, Vivi Rahmi, Sofia Rayhana, Rayhana Sianipar, Artha Yuliana Sinaga, Lia Rosa Veronika Siti Maimunah Siti Nurbaya Sitompul, Erly Sitorus, Elly Sitorus, Elly Nurita Supartiningsih - - Tambunan, Rika Puspita Tarigan, Malemta Tarigan, Mira Eka Diana Br Telaumbanua, Realisni Thaib, Cut Masyithah Turnip, Icha Wahyuni Yusuf, Faisal Zuhairiah Nasution, Zuhairiah