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All Journal Jurnal Pengabdian UntukMu NegeRI Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmaceutical and Clinical Research International Journal Of Science, Technology & Management (IJSTM) Molekul: Jurnal Ilmiah Kimia

Eka Nugraha, Sony

Universitas Sumatera Itara

Author-ID : 1363618

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Transportation

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Appropriateness of Antibiotic Utilization in Hospitalized Post-Surgery Patients Nasution, Azizah; Fashilah, Noor; Nugraha, Sony Eka
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 2 No. 1 (2019): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Abstract. One of the most common health problems related to surgery is infection which needs treatment with antibiotics. Inappropriate use of antibiotics results in many problems including microbial resistance, interference of the required clinical outcomes, increasing side effects of the provided antibiotics and health resources utilization, causing toxic effects to the body organs, and even death. This study aimed to evaluate the appropriateness of antibiotic utilization on post-surgery patients admitted to Haji Adam Malik (HAM) Hospital, Medan, Indonesia. This three-month prospective descriptive study was conducted to evaluate the appropriateness of antibiotic utilization based on Gyssens method categorized into appropriate and inappropriate (in terms of dose, interval, route, too long provision, too short provision, less effective, toxicity, price, and the spectrum), and trustable literatures on post-surgery patients assessed from their medical records (n=31) in HAM Hospital Medan. Most (54.8%) of the patients were females. The study proved that 23 (74.2%) of the patients received appropriate/rational antibiotic therapy and 8 (25.8%) of them received inappropriate antibiotic therapy consisted of problems with: inappropriate dose, 13%; too long duration, 3.2%); too short duration, 29%. More than a quarter of the patients received inappropriate dosages of antibiotics.

Sosialisasi Langkah Cuci Tangan Yang Benar Guna Mewujudkan Masyarakat Sehat Di Sman 2 Sibolga Sumaiyah Sumaiyah; Marianne Marianne; Embun Suci Nasution; Dewi Pertiwi; Sony Eka Nugraha
Jurnal Pengabdian UntukMu NegeRI Vol 4 No 1 (2020): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Washing hands is a simple step that can be improve the level of health of oneself, family and community. World Health Organization (WHO) has provided rules regarding good and proper washing steps, whereby the Indonesian government is promoting its socialization especially in the school environment. Senior High School (SMA) Negeri 2 Sibolga is one of the randomly selected schools to carry out the right hand washing step socialization according to WHO. The level of student’s knowledge about the correct steps for washing hands has been shown increase after socialization.

Training on Herbal Soap Preparation From the Extract Combination of Ketepeng Leaf and Sirih Leaf Sony Eka Nugraha; Marline Nainggolan; Jane Melita Keliat; Hetty Lendora Maha
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 7 No. 1 (2022): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

The problem of sanitation and hygiene is one of the problems faced by many people in Indonesia, especially in the current state of the Covid 19 pandemic. Not to mention the thing that is faced by the people of the Mabar village, Medan Deli sub-district, Medan City is the poor sanitation and hygiene of the community, especially those who live in dense settlements, so it is necessary to campaign for healthy living behaviors, one of which is through counseling on healthy living behaviors in maintaining personal health during the COVID-19 pandemic. and accompanied by training in the manufacture of antibacterial soap to increase public interest and awareness regarding the importance of healthy living. Soap products have developed into a primary need in today's society. These products are used every day by all levels of society, both upper, middle, and lower classes. The partners involved in community service are community groups in Neighborhood IX, Mabar sub-district, Medan Deli sub-district, Medan City. which is quite potential to be developed through a training program for making antibacterial herbal soaps, one of which is made from ketepeng leaves and betel leaves which are widely believed by the community to be effective in curing skin diseases. Several studies have proven that ketepeng and betel leaves have high antibacterial activity which have the potential to be developed into antibacterial soap products.Housewives and teenagers of productive age who are the targets of this service do not yet have productive activities. This training program is expected to provide business opportunities to the community so that it can improve the economy. The soap products produced can be used to meet household needs or can be sold to the surrounding community. With training in making antibacterial herbal soaps, expenses can be reduced and even can improve the household economy.

Training In Making Supplementary Foods and Stunting Prevention Education Through Android-Based â€œAnak Sehatâ€ Digital Application at Kelurahan Petapahan, Lubuk Pakam Sub-District, Deli Serdang Regency Sony Eka Nugraha; Marianne; Jane Melita Keliat
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i1.10346

Teaching, carrying out research for the development of science and applying knowledge, all three of which form a single unit known as the Tridharma of Higher Education. Community service is the third dharma of the Tridharma of Higher Education. The existence of community service is actually very important both for the management of the tertiary institution as well as for the existence of the tertiary institution in the community. The community service carried out is "Training on Making Complementary Food for Breastfeeding and Stunting Prevention Counseling Through the Android-Based "Healthy Children" Digital Application in Petapahan Village, Lubuk Pakam District, Deli Serdang Regency" The target group is mothers who have babies aged 12 months to 5 years in Posyandu Working area Petapahan Village, Lubuk Pakam District. Toddlerhood is an important period in the process of human development. Development and growth at that time determines the success of the growth and development of children in the next period. The period of growth and development at this age is a period that takes place quickly and will never be repeated, because it is often called the golden age or the golden age. Therefore, with this PkM activity, it can increase mother's awareness to pay attention to child development and prevent stunting.

Evaluation of Mother's Knowledge about Stunting and Observation of Stunting Incidents Based on the Growth of Toddlers at Posyandu Anggrek in Petapahan Village, Lubuk Pakam District, Deli Serdang Regency Sony Eka Nugraha; Marianne; Jane Melita Keliat; Manan Kumar; Dian Febiola P; Grace Mutiara Togatorop
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i1.11047

This community service aims to provide education about stunting and its prevention in order to increase awareness of mothers so that they can help their children in a period of normal growth and development while reducing the incidence of stunting in Indonesia. This community service activity is carried out by providing counseling related to stunting prevention and filling out questionnaires, especially for mothers who have babies aged 12 months to 5 years at Posyandu Anggrek to determine the effect of this activity on the level of knowledge of mothers regarding stunting issues.The community service carried out is " Evaluation of Mother's Knowledge about Stunting and Observation of Stunting incidents based on the growth of Toddlers at Posyandu Anggrek in Petapahan Village, Lubuk Pakam District, Deli Serdang Regency" The target group is mothers who have babies aged 12 months to 5 years in Posyandu Working area Petapahan Village, Lubuk Pakam District. Toddlerhood is an important period in the process of human development. Development and growth at that time determines the success of the growth and development of children in the next period. The period of growth and development at this age is a period that takes place quickly and will never be repeated, because it is often called the golden age or the golden age. Therefore, with this PkM activity, it can increase mother's awareness to pay attention to child development and prevent stunting.

Antibiofilm Formation Activities of Ethanol Extract of Curcuma domestica Val. Rhizome Against Multidrug-resistant Acinetobacter baumannii Halimah Raina Nasution; Yuandani; Abdi Wira Septama; Sony Eka Nugraha; Sufitni
International Journal of Science, Technology & Management Vol. 4 No. 4 (2023): July 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i4.883

Abstract. Multidrug resistance is still a major health problem worldwide. Biofilm formation was related to the resistance of bacteria mechanism. Acinetobacter baumannii, one of the bacteria that cause nosocomial infections, is given particular attention due to its high prevalence of resistance. The current study address observing the antibacterial activity and antibiofilm formation activity of Curcuma domestica rhizome extract against multidrug-resistant Acinetobacter baumannii (MDR A.baumannii). Curcuma domestica rhizome was macerated by ethanol 96%. Determination of Minimum Inhibitory Concentration (MIC) was carried out by the microdilution method. Antibiofilm formation analysis was determined by standard quantitative using crystal violet-stained assay. Ethanol extract of C. domestica possesses antibacterial activity against MDR A. baumannii with MIC value 250 µg/mL. Additionally, the ethanol extract of C. domestica could inhibit the biofilm formation of MDR A.baumannii, thus percentage of biofilm formed only 23.7% and significance different with control after analyzed using ANOVA post hoc test Tukey. According to these results, ethanol extract of C. domestica revealed antibacterial activity and had the potency in suppressing the biofilm formation of MDR A.baumannii, thus could be utilized in clinical application, especially in MDR A.baumannii infection. Keywords: Antibiofilm, antibacterial, Curcuma domestica, multidrug-resistant, Acinetobacter baumannii

Education and Training on the Utilization of Barangan Banana Peel into Liquid Soap as Home Industry in Siguci Village, North Sumatra Hetty Lendora Maha; Anayanti Arianto; Sony Eka Nugraha; Jane Melita Keliat
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 7 No. 2 (2022): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v7i2.7468

Indonesia one of country that is rich in natural plants that have an active compounds and are used by some people as active substances in the world of cosmetics such as soap. During this time, people only use bananas, limited to the use of the fruit, then the bananaâ€™s peel after consumption is only disposed of as waste. Several previous studies have stated that musa acuminata peel contain saponins, flavonoids, alkaloids and tannins. Based on the description, that musa acuminata peel can be used as a antibacterialâ€™s liquid soap. One of the musa acuminata producing areas in North Sumatra is Siguci Village, Deli Serdang Regency. The method used in this service are presentation about musa acuminata, their benefits, the active compounds they contain and the utilization of the waste of musa acuminata peels, as well as providing material on marketing techniques for home industry products. The results of this activity showed that as many as 20 residents were understands and is able to produce liquid soap made from musa acuminata peels, and can make attractive packaging., which can be seen from the results of the pre-test and post-test that were carried out during the educational activity.

Synergistic Antibacterial Activity of Curcuma domestica Val. Extract with Tetracycline Against Multidrug-resistant Acinetobacter baumannii Nasution, Halimah Raina; Yuandani, Yuandani; Septama, Abdi Wira; Nugraha, Sony Eka; Sufitni, Sufitni; Khairunnisa, Nur Aini
Molekul Vol 19 No 1 (2024)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2024.19.1.8593

Infections caused by multidrug-resistant (MDR) bacteria are on the rise globally. MDR is facilitated by overexpression of efflux pump and permeability changes of membrane. Acinetobacter baumannii is a pathogenic germ that causes a major problem in infection, also, there has been an increase in the incidence of resistance to various antibiotics. The present study highlights the synergistic of ethanolic extract of Curcuma domestica (EECD) rhizome with tetracycline against multidrug-resistant A. baumannii (MDR-Ab). Assessment of Minimum Inhibitory Concentration (MIC) was determined by microdilution using 96-well plates. The synergistic effect of EECD and tetracycline was determined by checkerboard method. The effect of EECD and tetracycline combination was investigated by bacteriolytic activity and inhibition of efflux pump by Ethidium Bromide (EtBr) accumulation assay. EECD presented the MIC value 250 µg/mL against MDR-Ab. Fractional Inhibitory Concentration Index (FICI) value of EECD and tetracycline combination was 0.4, which showed their synergistic effect. Additionally, the combination of EECD and tetracycline could inhibit the efflux pump in MDR-Ab. This combination can also compromise cell integrity by altering membrane permeability thus lysing the bacteria cells. According to these results, EECD and tetracycline combination has synergistic effects at some sites of action, and thus could be used as a breakthrough to overcome infection problems due to MDR-Ab. Keywords: Acinetobacter baumannii, antibacterial, Curcuma domestica, multidrug-resistant, tetracycline

Antibacterial activity of Ethanol Extract of Purple Passion Fruit Peel (Passiflora edulis Sims) on Staphylococcus aureus and Escherichia coli Sony Eka Nugraha; Suryadi Achmad; Erly Sitompul
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 2 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Abstract.North Sumatera is the central production of purple passion fruit in Indonesia. Passion fruit was processing into beverage product that produced passion fruit peel waste. The passion fruit peel has potential effect as a sources of medicine which is need to be examined such as its antibacterial effect. The purpose of this study was to determine the characterization of simplicia, phytochemical screening and antibacterial activity of ethanol extract of purple passion fruit peel against Staphylococcus aureus and Escherichia coli. The simplicia powder was examined its characteristic include water content, water soluble extract, ethanol soluble extract, total ash and acid insoluble ash assay. The extraction was process by percolation method using ethanol 96% , then tested antibacterial activity against Staphylococcus aureus and Escherichia coli using agar diffusion method with paper discs.The result showed that the simplicia characteristic of passion fruit peel were water content of 8.64%, water soluble extract of 31.69%, ethanol soluble extract of 13.02%, ash total of 7.89%, and insoluble ash in acid of 0.816%. The phytochemical screening simplicia and ethanol extract showed the presence of flavonoid, glycoside, saponin, tannin and steroid/triterpenoid.The antibacterial activity test showed that the ethanol extract has an effective inhibition at the concentration of 300 mg/ml against Staphylococcus aureus and Escherichia coli, it showed dose dependent manner. Keywords: Passiflora edulis Sims, antibacterial, passion fruit peel, Staphylococcus aureus and Escherichia coli

Antibacterial Activity of Ethyl Acetate Fraction of Passion Fruit Peel (Passiflora Edulis Sims) on Staphylococcus Aureus and Escherichia Coli Sony Eka Nugraha; Suryadi Achmad; Erly Sitompul
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 2 No. 1 (2019): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

North Sumatera is one of the central areas of purple passion fruit production in Indonesia. Processing passion fruit into beverage products (passion fruit juice) produces peel has not been utilized. The use of passion fruit skin needs to be studied so that it can be useful as a raw material for antibacterial drug preparations. The aim of this study was to determine the phytochemical constituent screening and antibacterial activity of ethyl acetate fraction of purple passion fruit peel against Staphylococcus aureus and Escherichia coli. Simplicia and ethyl acetate fraction were determinated its phytochemical properties. The extraction process by percolation method using ethanol 96% and continue to fractionation process by liquid liquid extraction method using n-hexane and ethyl acetate. The antibacterial activity were tested against Staphylococcus aureus and Escherichia coli using agar diffusion method with paper discs. The result showed that the simplicia characteristic of passion fruit peel were water content of 8.64%, water soluble extract of 31.69%, ethanol soluble extract of 13.02%, ash total of 7.89%, and insoluble ash in acid of 0.816%. The phytochemical screening simplicia and ethyl acetate fraction showed the presence of flavonoids, glycosides, saponins and tannins. The antibacterial activity test showed that the ethyl acetate fraction has an effective inhibition at the concentration of 100 mg/ml against Staphylococcus aureus and Escherichia coli, it showed dose dependent manner. The ethyl acetate fraction of passion fruit peel (Passiflora edulis Sims) has an antibacterial activity on Staphylococcus aureus and Escherichia coli

Co-Authors . Marianne Abdi Wira Septama Abdi Wira Septama Anayanti Arianto Dewi Pertiwi Dian Febiola P Embun Suci Nasution Erly Sitompul Erly Sitompul Fashilah, Noor Grace Mutiara Togatorop Halimah Raina Nasution Hetty Lendora Maha Jane Melita Keliat Jane Melita Keliat Khairunnisa, Nur Aini Manan Kumar Marianne Marline Nainggolan Nabila Nabila Nasution, Azizah Nasution, Halimah Raina Rony Abdi Syahputra Sufitni Sumaiyah Sumaiyah Suryadi Achmad Suryadi Achmad Yuandani

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