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All Journal Jurnal Pengabdian UntukMu NegeRI Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmaceutical and Clinical Research International Journal Of Science, Technology & Management (IJSTM) Molekul: Jurnal Ilmiah Kimia
Eka Nugraha, Sony
Universitas Sumatera Itara
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Phytochemical Screening and Antibacterial activity of Polyphenol rich Extract of Passion Fruit Pericarp (Passiflora edulis Sims) on Propionibacterium acnes Sony Eka Nugraha; Rony Abdi Syahputra; Nabila Nabila
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 6 No. 1 (2023): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v6i1.17765

Abstract

Indonesia's primary hub for cultivating purple passion fruit is North Sumatera. The passion fruit was transformed into a beverage product, which led to the creation of passion fruit pericarp trash. The potential medicinal properties of the passion fruit pericarp, particularly its antibacterial impact, need to be further explored. This study aimed to assess the phytochemical composition and antibacterial properties of an ethanol extract derived from the pericarp of purple passion fruit against Propionibacterium acnes. The extraction was performed using the percolation method with 96% ethanol. The antibacterial activity against Propionibacterium acnes was assessed using the agar diffusion method with paper discs. The phytochemical screening of the simplicia and ethanol extract revealed the existence of flavonoid, glycoside, saponin, tannin, and steroid/triterpenoid compounds. The ethanol extract exhibited significant antibacterial activity against Propionibacterium acnes at a dosage of 300 mg/ml, demonstrating a dose-dependent impact.
Co-Authors . Marianne Abdi Wira Septama Abdi Wira Septama Anayanti Arianto Dewi Pertiwi Dian Febiola P Embun Suci Nasution Erly Sitompul Erly Sitompul Fashilah, Noor Grace Mutiara Togatorop Halimah Raina Nasution Hetty Lendora Maha Jane Melita Keliat Jane Melita Keliat Khairunnisa, Nur Aini Manan Kumar Marianne Marline Nainggolan Nabila Nabila Nasution, Azizah Nasution, Halimah Raina Rony Abdi Syahputra Sufitni Sumaiyah Sumaiyah Suryadi Achmad Suryadi Achmad Yuandani