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All Journal Jurnal Kedokteran Syiah Kuala Jurnal Berkala Epidemiologi Indonesian Journal of Tropical and Infectious Disease Sari Pediatri Paediatrica Indonesiana Health Notions Jurnal Gema Ngabdi Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Indian Journal of Forensic Medicine & Toxicology
Ismoedijanto
Departemen Ilmu Kesehatan Anak, Fakultas Kedokteran, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Faktor Determinan Klinis pada Malaria Anak Parwati SB; Simplicia MA; Ismoedijanto Ismoedijanto
Sari Pediatri Vol 3, No 2 (2001)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp3.2.2001.106-14

Abstract

Wabah malaria ditemukan di berbagai tempat di Indonesia, antara lain di pantaiselatan Jawa Tengah, DIY dan Jawa Timur, namun penyebaran penyakit terbesarterdapat di daerah luar Jawa-Bali kawasan timur. Masalah malaria bersifat localspecific. Manifestasi malaria pada anak berbeda dan kurang spesifik dibanding orangdewasa, dan belum ditemukannya definisi klinis berupa keluhan dan atau gejalaklinis malaria pada anak di daerah endemis tertentu. Hal ini menyebabkanoverdiagnosis dan overtreatment untuk malaria dan kemungkinan terabaikannyapengobatan untuk penyakit lain. Penelitian ini bertujuan mengidentifikasi keluhandan atau gejala klinis yang dapat digunakan sebagai determinan klinis malaria padaanak. Hasil penelitian ini berguna bagi pasien demam atau riwayat demam dalamsatu minggu terakhir, dan yang berada di daerah endemis malaria. Dilakukan suatustudi cohort yang merupakan penelitian gabungan kuantitatif dan kualitatif berlokasiKabupaten Sikka- NTT, selama bulan Mei-Juni 1999. Di antara 165 anak yangmemenuhi kriteria inklusi, 79 pasien (47,9%) dengan definitif malaria dan 86 pasienbukan malaria (52,1%), sebagian besar pasien adalah kelompok umur 1-4 tahun(64,6%) Dari analisis gabungan antara uji Kai-kuadrat dan metode Delphi terdapatkesesuaian mengenai keluhan dan gejala klinis malaria yang prominen, namunmengingat insidensi penyakit malaria pada tiap kelompok umur, determinan klinispada penelitan ini paling cocok diterapkan pada kelompok umur 1-4 tahun yaitusplenomegali, menggigil, pucat, dan hiperpireksia. Perlu dilakukan studi serupa didaerah endemis lain.
THE ANTIDIPHTHERIA ANTIBODIES OF SEROEPIDEMIOLOGY SURVEY AMONG ADOLESCENTS IN BANGKALAN AND KEDIRI DISTRICTS Dominicus Husada; Kristina Marbun; Desy Primayani; Leny Kartina; Dwiyanti Puspitasari; Parwati Setiono Basuki; Ismoedijanto Moedjito; Aris Wiji Utami; Eveline Irawan
Jurnal Berkala Epidemiologi Vol. 7 No. 2 (2019): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.595 KB) | DOI: 10.20473/jbe.V7I22019.94-102

Abstract

Background: An increase in diphtheria cases has occurred in East Java Province since 2011. The resistance level to diphtheria is considered as the most important cause. Purpose: The study aims analyzed the immunity level immunity to diphtheria in adolescents aged 16-18 years old in Bangkalan and Kediri Districts. Methods: This study was a cross-sectional study, conducted on students in eleven grade of senior high schools (SMAN) from both districts. The inclusion criteria included being 16-18 years old and students in eleven grades of senior high schools in Bangkalan and Kediri. This study was approved by their parents/guardians. The exclusion criteria included immunocompromised students and those who have a history of diphtheria infection. The data were obtained from 204 samples, 89 samples in Bangkalan, and 115 samples in Kediri. The antidiphtheria antibodies examination was carried out by the Vero cell method. The antibodies levels were grouped according to WHO standard, consist of vulnerable, basic, full, and long-term. Further analysis was done with 2 tiers of immunity, consist of immune and vulnerable. Results: The immunization coverage for basic and booster diphtheria vaccine is better in Kediri than in Bangkalan. In contrast, levels of antibodies samples in Bangkalan District is better. The participants who were immune in Bangkalan were higher than those in Kediri (91% vs. 44.3%). Conclusion: The immunity adolescents of Bangkalan is higher than in adolescent Kediri District. The adolescents in Kediri have a greater risk to get infected by the disease
Persistent proteinuria as an indicator of renal disease in HIV-infected children Yuni Hisbiiyah; Risky Vitria Prasetyo; Dwiyanti Puspitasari; Ninik Asmaningsih Soemyarso; Ismoedijanto Moedjito; Mohammad Sjaifullah Noer
Paediatrica Indonesiana Vol 56 No 6 (2016): November 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (104.857 KB) | DOI: 10.14238/pi56.6.2016.343-9

Abstract

Background Persistent proteinuria (microalbuminuria) has been reported to be a precursor of HIV-related renal disease. Screening allows for early management in order to prevent the progression of renal disease and decrease morbidity and mortality associated with chronic kidney disease in HIV. Several studies have been done on renal manifestation in HIV-infected children from American and African regions, but similar studies from Asia are lacking.Objective To determine the prevalence of persistent proteinuria in HIV-positive children on antiretroviral therapy (ARV) in Dr. Soetomo Hospital, Surabaya.Methods A cross-sectional study on children with HIV and treated with  highly active antiretroviral therapy (HARRT) was done from August 2014 to February 2015. Microalbuminuria was measured by the ratio of urine albumin to creatinine (ACR), while proteinuria was measured by dipstick. Measurements were performed 3 times in 4-8 weeks. All subjects underwent complete evaluation of blood tests, serum creatinine, blood urea nitrogen (BUN), CD4 counts, and urinalysis. Data were analyzed using Chi-square and logistic regression tests.Results Of 38 children on HARRT enrolled in this study, 2 subjects developed acute kidney injury (AKI), 4 subjects were suspected to have urinary tract infection (UTI), and 1 subject was suspected to have urinary tract stones. The prevalence of persistent microalbuminuria was 2.6%. There was no correlation between immunological status, WHO clinical stage, or duration of ARV and the incidence of persistent proteinuria (P>0.05).Conclusion The prevalence of persistent proteinuria is  lower in younger HIV-infected children at a non-advanced stage and HIV-infected children with normal immunological status who are on HAART. We provide baseline data on the renal conditions of HIV-infected children in the era of HAART, before tenovofir is  increasingly used as an antiretroviral therapy regimen in Indonesia.
Thiamphenicol in the treatment of cholera in children Haroen Noerasid; Eko Sujanto; Ismoedijanto Ismoedijanto; Djoko Soejono; I. G. G. Djelantik; Surata Surata
Paediatrica Indonesiana Vol 21 No 9-10 (1981): September - October 1981
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi21.9-10.1981.197-204

Abstract

A study has been performed to measure the efficacy of thiamphenicol by comparing it with tetracycline as a standard drug. Eighty bacteriologically confirmed cholera patients were included in this study.Among them, 41 patients were treated with thiamphenicol while the other39 with tetracycline.Stool volume, duration of diarrhea and duration of hospitalization were higher in the thiamphenicol group. And the volume of intravenous and oral fluid therapy were less in the tetracycline group.Positive bacteriologic examinations of the second samples (taken on the second day of hospitalisation) of the thiamphenicol grollp were 41.46% as compared with 17.94% of the tetracycline group. But almost all o{ the third samples of both groups were negative.Clinical success rate of thiamphellicol was 95.12% and tetracycline was 100%. Thiamphenicol appeared to be effective against cholera in children.
A case of pediatric AIDS in Dr. Sutomo Hospital Surabaya, Indonesia Ismoedijanto Ismoedijanto; Rosanti Yustina; Rahayu Tri Lestari; Hidayat Burhan
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (114.301 KB) | DOI: 10.14238/pi41.2.2001.121-124

Abstract

We report a 2-year old girl who suffered from HIV. The diagnosis was based on history, clinical findings, andlaboratory work-up. Suspicion of the presence of HIV was started when the girl continued to have wasting syndrom e withseveral focal infections unresponsice to ordinary treatment. The patient past away following severe diarrhea and apparentlysepsis.
The Role of PKK in the Immunization Progmmme Soegen Soegijanto; Dwi Atmadji S.; Parwati Setiono B.; Ismoedijanto Ismoedijanto; Widodo D. M.; Aried Kaspan
Paediatrica Indonesiana Vol 29 No 7-8 (1989): July - August 1989
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi29.7-8.1989.133-40

Abstract

A mid term evaluation of the immunization programme had been carried out in East Java from November 27, 1987 to December 6, 1987. The team consisted of various multidisciplines comprising members of the WHO (3), the Department of Health (4), the Medical Faculty (1), the PKK group (1), and Bangdes. Data showed that the Posyandu, the Health Centres, Hospitals and private doctors contributed to the programme by 69%, 28%, 2% and 1% respectively. It was obvious that although not satisfactory, the Posyandu was by for the mostly committed, reflecting the role of the PKK group especially in terms of encouraging mothers to bring their children to the Posyandu. As one face facts of low educated mothers, mothers being trapped in their routine daily activities, or having had inconvenient medical experience, a low motivation towards immunization might be anticipated, which in turn leads to a low coverage of immunization. Taking into consideration of how the PKK group plays its role in the immunization programme, attempts made to improve knowledge on immunizable diseases and their measures for prevention would undoubtly be an important means of support to gain the aim of immunization.
Jadwal Imunisasi Anak Usia 0 – 18 Tahun Rekomendasi Ikatan Dokter Anak Indonesia Tahun 2023 Mei Neni Sitaremi; Soedjatmiko Soedjatmiko; Hartono Gunardi; Nastiti Kaswandani; Setyo Handryastuti; Raihan Raihan; Cissy B Kartasasmita; Ismoedijanto Ismoedjianto; Kusnandi Rusmil; Zakiudin Munasir; Dwi Prasetyo; Gatot Irawan Sarosa; Hanifah Oswari; Dominicus Husada; Ari Prayitno; Martira Maddepunggeng; Sri Rejeki H Hadinegoro.
Sari Pediatri Vol 25, No 1 (2023)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp25.1.2023.64-74

Abstract

Satuan Tugas Imunisasi Ikatan Dokter Anak Indonesia (IDAI) secara berkala mengevaluasi jadwal imunisasi untuk menyesuaikan dengan vaksin baru, program imunisasi Kemenkes, WHO position paper dan sumber-sumber lain. Di dalam jadwal imunisasi rekomendasi IDAI tahun 2023 ini ada beberapa tambahan antara lain vaksin dengue baru, dan keterangan tambahan beberapa vaksin lain. Untuk memudahkan dalam melaksanakannya dilampirkan juga tabel jadwal imunisasi tahun 2023. Untuk memahami dasar pertimbangan jadwal imunisasi dan perubahannya perlu mempelajari uraian di dalam artikel ini dan keterangan di bawah tabel tersebut untuk diterapkan ke dalam layanan imunisasi.
Comparison of Neutralizing Antibody Response to Type 1 Polio Virus on Healthy Infants Receiving either Oral Monovalen Polio Vaccine Type 1 or Oral Trivalen Polio Vaccine Given with Basic DTP/Hb Immunization Hartati, Edim; Ismoedijanto, Ismoedijanto; Soegijanto, Soegeng
Indonesian Journal of Tropical and Infectious Disease Vol. 1 No. 1 (2010)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1426.315 KB) | DOI: 10.20473/ijtid.v1i1.3715

Abstract

In March 2005, there was outbreak of Polio-1 and expanded throughout Java and Sumatera island. Oral monovalent polio vaccinetype 1 (mOPV1) had succeeded in evereeming polio outbreak in Indonesia in 2005. This study aimed to compare neutralizing antibodyresponse to type 1 polio virus in healthy infants receiving either mOPV1 or oral trivalent Polio Vaccine (tOPV), given with other basicvaccination (DTP/HB). Randomized controlled singel blind clinical trial on healthy infants range age 42 to 80 days who had receivedfirst oral polio vaccine before 1 month of age. Trial group received mOPV1 and control group tOPV, each had 3 times of vaccination.Blood samples were taken three times (pre vaccination, post second and third vaccination) for measurement of neutralizing antibody topolio virus. Thirty subjects from mOPV1 group and 29 from tOPV group were analyzed. Post second vaccination, mOPV1 group (456)had more increase in geometric mean titer of neutralizing antibody than tOPV group (317) but not significant (p=0.514). Post thirdvaccination the level of neutralizing antibody titer was almost equal in both groups. Proportion of seroconversion to type 1 polio virusin mOPV1 group 53.9%, 57.7% and tOPV group 25.9%, 41.7% (on second and third evaluation respectively), both were statisticallyinsignificant. Antibody response measured by neutralizing antibody titer and proportion of seroconversion on antibody to type 1 poliovirus in healthy infants receiving mOPV1 vaccination was similar to they receiving tOPV.
PROGNOSTIC FACTORS OF SEVERE DENGUE INFECTIONS IN CHILDREN Baiduri, Senja; Husada, Dominicius; Puspitasari, Dwiyanti; Kartina, Leny; Basuki, Parwati Setiono; Ismoedijanto, Ismoedijanto
Indonesian Journal of Tropical and Infectious Disease Vol. 8 No. 1 (2020)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v8i1.10721

Abstract

The  incidence of dengue fever increase annually and can increase morbidity and mortality. Dengue fever is mosquito-borne disease and caused by one of four serotype dengue viruses. Severe dengue is characterized either by plasma leakage, fluid accumulation, respiratory distress, severe bleeding, or organ impairment. Mortality and serious morbidity of dengue were caused by several factors including the late recognition of the disease and the changing of clinical signs and symptoms. Understanding the prognostic factors in severe dengue will give early warning to physician thus decreasing the morbidity and mortality, and also improving the treatment and disease management. The aim of this study was to analyze the prognostic factors of severe dengue infection in children. This study was observational cohort study in children (2 months-18 years) with dengue infection according to WHO 2009 criteria which admitted in  Soetomo and Soewandhie Hospital Surabaya. Analysis with univariate, bivariate and multivariate with IBM SPSS Statistic 17. All patients were confirmed by serologic marker (NS-1 or IgM/IgG Dengue). Clinical and laboratory examination such as complete blood count, aspartate aminotrasnferase (AST), alanine aminotrasferase (ALT), albumin, and both partial trombocite time and activated partial trombosit time (PTT and aPPT) were analyzed comparing nonsevere dengue and severe dengue patients. There were 40 subjects innonsevere and 27 subjects with severe dengue infection. On bivariate analysis, there were significant differences of nutritional status, abdominal pain, petechiae, pleural effusion, leukopenia, thrombocytopenia, hypoalbuminemia, history of transfusion, increasing AST>3x, prolonged PPT and APTT between severe and nonsevere dengue group. After multivariate analyzed, the prognostic factors of severe dengue were overweight/obesity (p=0.003, RR 94), vomiting (p=0.02, RR 13.3), hepatomegaly (p=0.01, RR=69.4), and prolonged APTT (p=0.005, RR=43.25). In conclusion, overweight/obesity, vomiting, hepatomegaly, and prolonged APTT were prognostic factors in severe dengue infection in children.Those factors should be monitored closely in order to reduce the mortality and serious morbidity.
Profil Isolat Corynebacterium diphtheriae Toksigenik di Jawa Timur Tahun 2012-2017 Sugi Deny Pranoto Soegianto; Adi Pramono Hendrata; Eveline Irawan; Ismoedijanto; Dominicus Husada
Majalah Kedokteran Indonesia Vol 69 No 2 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.2-2019-75

Abstract

Introduction: Diphtheria has been reported as an outbreak in some regions inIndonesia, most of the cases are from East Java.Objective: To describe the profile of toxigenic Corynebacterium diphtheriaeisolates in East Java. Methods. An descriptive study from August 20th -November 30th, 2018. Isolates was selected by cluster random sampling. The viability and toxigenicity testwere done in BBLK Surabaya. Viable and toxigenic isolates were done forcharacteristic analysis. Result: A total of 114 isolates, 6 were non-viable, 108 were viable and toxi-genic. The majority of the hosts were male (58,3%), median age 6,5-year-old(minimum 1, maximum 14-year-old), 50% from the 1-5-year-old age group. Highest origin of isolates from patients (78,7%) rather than carriers (21,3%).The most isolates from Madura (47,2%) and horseshoe area (20,4%). Most ofthem (74.1%) were taken from a pharyngeal swab rather than a nasal swab(25,4%). Mitis was 76,9% and gravis was 23,1%. Conclusion: In this study, the majority of toxigenic Corynebacterium diphtheriae were found in the 1-5-year-old age group and most of them domi-cile in Madura and horseshoe area. Most of the isolates were taken from apharyngeal swab of patients. Mitis was the major variant.
Co-Authors Adi Pramono Hendrata Ari Prayitno Ari Prayitno Aried Kaspan Aris Wiji Utami Baiduri, Senja Bangkit Putrawan Basuki, Setio Budi Utomo Catarina Rani Cissy B Kartasasmita Cissy B. Kartasasmita Cissy B. Kartasasmita Darto Saharso Desy Primayani Djoko Soejono Dominicus Husada Dwi Atmadji S. Dwi Prasetyo Dwi Prasetyo Dwi Prasetyo Dwiyanti Puspitasari, Dwiyanti Eko Sujanto Ernawati Ernawati Ernawati Ernawati Eveline Irawan Eveline Irawan Gatot Irawan Sarosa Gatot Irawan Sarosa Gatot Irawan Sarosa Hanifah Oswari Hanifah Oswari Haq, Arini Haroen Noerasid Hartati, Edim Hartono Gunardi Hartono Gunardi Hendrata, Adi Pramono Hidayat Burhan Hilwana, Lutifta Husada, Dominicius I Dewa Gede Ugrasena I Gusti Ngurah Twi Adnyana I. G. G. Djelantik Irawan, Eveline Irene Ratridewi Kartina, Leny Kristina Marbun Kusnandi Rusmil Kusnandi Rusmil Kusnandi Rusmil Martira Maddepunggeng Martira Maddepunggeng Mei Neni Sitaremi Mei Neni Sitaresmi Mohammad Sjaifullah Noer Mustikasari, Rahma Ira Nastiti Kaswandani Nastiti Kaswandani Ninik Asmaningsih Soemyarso Parwati S. Basuki Parwati SB Parwati Setiono Basuki Rahayu Tri Lestari Raihan Raihan Raihan Raihan Retno Asih Setyoningrum Risa Etika, Risa Risky Vitria Prasetyo Rochmayanti, Ucik Rosanti Yustina Savitri Laksmi Winaputri Setyo Handryastuti Setyo Handryastuti Simplicia MA Soedjatmiko Soedjatmiko Soedjatmiko Soegen Soegijanto Soegeng Soegijanto Soegianto, Sugi Deny Pranoto Sri Rejeki H Hadinegoro. Sri Rezeki S. Hadinegoro Sri Rezeki S. Hadinegoro Sugi Deny Pranoto Soegianto Surata Surata Susanto Nugroho Syawitri P. Siregar Ucik Rochmayanti Widodo D. M. Widodo Darmowandowo Yuni Hisbiiyah Zakiuddin Munasir Zakiudin Munasir Zakiudin Munasir