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Gambaran Histopatologi Spesimen Gaster post Laparoscopic Sleeve Gastrectomy di Rumah Sakit Sumber Waras Jakarta Barat Sartono, Stefanny; Sugiharto, Sony
Bahasa Indonesia Vol 23 No 3 (2024): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v23i3.5488

Abstract

Pendahuluan: Obesitas seringkali menimbulkan berbagai masalah kesehatan. Laparoscopic Sleeve Gastrectomy (LSG) merupakan pilihan terapi bagi pasien obesitas berat yang gagal dengan perubahan gaya hidup atau terapi obat. Publikasi perubahan histopatologi spesimen gaster pasca LSG masih sedikit. Tujuan penelitian ini adalah mempelajari data demografi dan gambaran histopatologi pasien yang telah menjalani LSG. Metode: Penelitian ini adalah penelitian deskriptif potong lintang dengan jumlah sampel sebanyak 140 pasien dan berlokasi di RS Sumber Waras, Jakarta Barat, Indonesia. Variabel penelitian adalah jenis kelamin, umur, dan gambaran histopatologi. Data pasien yang menjalani LSG antara bulan Desember 2018 – Desember 2023 dikumpulkan secara purposive sampling. Hasil: Hasil penelitian menunjukkan 140 pasien telah menjalani LSG dan diperiksa gambaran histopatologinya, perempuan 114 orang (81,4%) dan laki-laki 26 orang (18,6%). Usia penderita berkisar antara 13 hingga 67 tahun, dan sebagian besar pada kelompok usia 31-40 tahun. Histopatologi spesimen terbanyak adalah gastritis kronik sebanyak 37,2%, disusul gambaran gaster normal sebanyak 31,4%, agregat limfoid (18,6%), polip kelenjar fundus (4,3%), gastropati kongestif (2,7%), gastritis atrofik (1,6%), leiomioma (1,6%), hiperplasia kelenjar fundus (1,1%), polip inflamatorik (0,5%), divertikel (0,5%), dan neurofibroma (0,5%). Simpulan: Gambaran histopatologi yang didapatkan pada spesimen gaster pasca LSG bervariasi dari gaster normal, lesi non neoplasma, dan neoplasma jinak yaitu leiomioma dan neurofibroma. Hasil temuan penelitian ini menunjukkan perlunya pemeriksaan histopatologi rutin pada spesimen LSG.
Histopathological Features of Colorectal Polyps and Tumors at Sumber Waras Hospital from 2015-2023 Jovial Jovial; Sony Sugiharto
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 6, No 2 (2024): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v6i2.20632

Abstract

Colorectal tumours pose a significant global health issue, including in Indonesia. The development of colorectal polyps and tumours involves various risk factors such as poor lifestyle choices, male gender, and advancing age. This study aims to determine the characteristics of patients with colorectal polyps and tumours, their histopathological features, and the most common gender and age group for each histopathological feature. The study was conducted at Sumber Waras Hospital, implementing a descriptive cross-sectional approach with retrospective data of 113 patients with colorectal polyps and tumours from 2015-2023. This study's findings indicate that most patients were males (58.4%), with the highest number in the 61-70 age group (29.2%). Among non-neoplastic lesions, inflammatory polyp was the most prevalent histopathological finding (18.3%), whereas adenocarcinoma (NOS) was the most common feature among all neoplastic lesions (53.3%). All non-neoplastic lesions were predominantly found in males. Neoplastic lesions such as adenocarcinoma (NOS), mucinous adenocarcinoma, neuroendocrine tumours, and lymphoma were also more prevalent in males. In contrast, adenoma, signet ring, and squamous cell carcinoma were more frequently found in females. Non-neoplastic lesions such as hamartoma were most common in the 11-20 age group, while hyperplastic and inflammatory polyps were prevalent in the 61-70 age group. Neoplastic lesions such as adenoma were most prevalent in the 61-70 and 71-80 age groups; mucinous adenocarcinoma and lymphoma in the 51-60 age group; adenocarcinoma (NOS), squamous cell carcinoma, and neuroendocrine tumours in the 61-70 age group; as well as signet ring cell carcinoma in the 71-80 age group. To reduce the prevalence of colorectal polyps and tumours, it may be crucial to consider performing histopathological examinations for a thorough evaluation, given their wide variety that requires different diagnostic and treatment strategies.  Keywords: Age Group, Colorectal Polyp, Colorectal Tumor, Gender, Histopathological Features
Relationship of Knowledge About Cervical Cancer and PAP SMEAR with Early Detection Behavior of PAP SMEAR Rahmi Syahputri; Sony Sugiharto
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 5, No 4 (2023): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v5i4.15777

Abstract

Cervical cancer is the third leading cause of death in Indonesia.  Cervical cancer is usually only diagnosed when the cancer has entered an advanced stage. So the need for early detection as an effort to prevent cervical cancer. One of the most effective and commonly used methods to detect cervical cancer is Pap smear.  The purpose of this study was to see the relationship between knowledge about cervical cancer and Pap smear with Pap smear early detection behavior.  This study used analytic method with quantitative approach. The population of this study were all married women in Pancoran District, South Jakarta. Then, consecutive non-random sampling technique was used and 153 respondents were obtained with a questionnaire as a tool to obtain research data. Data collection was carried out from September to November 2023. Followed by analysis with the Chi-Square test using SPSS. Based on the results of the study, 58.2% of respondents have good knowledge and 72.5% of respondents have not done Pap smear examination from 158 respondents, there is no significant relationship between knowledge about cervical cancer and Pap smear with Pap smear early detection behavior (p-value=0.093). The conclusion of this study is that there is no relationship between knowledge about cervical cancer and Pap smear with early detection behavior of Pap smear in Pancoran District, South Jakarta.  For further research, it is recommended to provide insight into cervical cancer in depth so that readers are aware of the importance of early detection of cervical cancer.  Keyword: Cervival cancer, Knowledge, Pap smear
Prevalensi Tumor Jaringan Lunak Berdasarkan Gambaran Histopatologi di Rumah Sakit Sumber Waras Jakarta Pandean, Felicia; Sugiharto, Sony
MAHESA : Malahayati Health Student Journal Vol 5, No 6 (2025): Volume 5 Nomor 6 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i6.18085

Abstract

ABSTRACT Soft tissue tumors are abnormal cell growths in tissues like fat, muscle, blood vessel, fibrous tissue, and peripheral nerve. Their prevalence and types are highly varied and diverse. In 2024, the United States is expected to report 13,590 cases of malignant soft tissue tumors with 5,200 deaths. Research on soft tissue tumors in Indonesia is still not much. Histopathological examination is the gold standard for diagnosis, grading, and treatment planning. This study examines the prevalence and histopathological findings of soft tissue tumors at Sumber Waras Hospital in West Jakarta from 2015 to 2023. This study is a descriptive cross-sectional with a retrospective approach. The research sample consisted of 153 patients with a clinical diagnosis of soft tissue tumors from 2015 to 2023, with anatomical pathology reports that met the inclusion and exclusion criteria. The data obtained were then organized into tables and analyzed using the SPSS program. Out of 153 patients, soft tissue tumors were most frequently found in women, with a total of 83 cases (54.2%), while in men there were 70 cases (45.8%). Soft tissue tumors were most commonly diagnosed in 41-50 years, with 40 patients (26.1%). The common type was lipoma, with 103 patients (67.3%), followed by hemangioma with 10 patients (6.5%). The prevalence of soft tissue tumors at Sumber Waras Hospital from 2015 to 2023 was 153 patients, with the majority being female. The most affected age group was 41-50 years, and lipomas were the most common type of tumors. Keywords: Age, Gender, Histopathological findings, Soft tissue tumor  ABSTRAK Tumor jaringan lunak merupakan pertumbuhan abnormal sel pada jaringan seperti lemak, otot, pembuluh darah, jaringan fibrosa dan saraf tepi. Prevalensi dan jenis tumor jaringan lunak sangat beragam dan berbeda-beda. Pada tahun 2024, di Amerika Serikat diperkirakan terdapat 13.590 kasus tumor jaringan lunak ganas, dengan 5.200 kematian. Penelitian tumor jaringan lunak di Indonesia masih sangat sedikit. Pemeriksaan histopatologi merupakan baku emas untuk menegakkan diagnosis, grading dan penentuan terapi. Studi ini  mengkaji prevalensi dan gambaran histopatologi tumor jaringan lunak di Rumah Sakit Sumber Waras Jakarta pada tahun 2015-2023. Studi ini merupakan studi deskriptif potong lintang dengan pendekatan retrospektif. Sampel penelitian berupa hasil pemeriksaan patologi anatomi 153 pasien dengan diagnosis klinis tumor jaringan lunak dari tahun 2015-2023 yang telah memenuhi kriteria inklusi dan eksklusi. Data yang didapat akan dikumpulkan dalam bentuk tabel dan dianalisis dengan program SPSS. Hasil dari studi ini adalah dari 153 pasien, tumor jaringan lunak paling banyak ditemukan pada perempuan dengan total 83 pasien (54,2%), sementara pada laki-laki ditemukan sebanyak 70 pasien (45,8%). Tumor jaringan lunak sering ditemukan pada kelompok usia 41-50 tahun dengan total 40 pasien (26,1%). Tipe tersering yang ditemukan adalah lipoma dengan total 103 pasien (67,3%), diikuti dengan hemangioma sebanyak 10 pasien (6,5%). Prevalensi tumor jaringan lunak di Rumah Sakit Sumber Waras pada tahun 2015-2023 berjumlah 153 pasien, sebagian besar perempuan, ditemukan paling banyak pada kelompok usia 41-50 tahun, dan lipoma merupakan jenis tumor yang paling banyak.  Kata Kunci: Usia, Jenis Kelamin, Gambaran Histopatologi, Tumor Jaringan Lunak
Prevalensi ekspresi PD-L1 Sp263 pada kanker paru di MRCCC Siloam Hospital Hiu, Christian Hendrik; Sugiharto, Sony
Tarumanagara Medical Journal Vol. 7 No. 1 (2025): TARUMANAGARA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/tmj.v7i1.34094

Abstract

Kanker paru menjadi penyebab kematian paling banyak di dunia. Kanker paru ialah kanker kedua terbanyak di Indonesia dan lebih banyak menyerang laki-laki. Perkembangan penelitian molekuler telah memberikan alternatif pada terapi kanker paru seperti target terapi dan imunoterapi. Saat ini, PD-1 inhibitor digunakan sebagai imunoterapi pada pasien kanker paru yang menunjukan hasil pemeriksaan PD-L1 positif. Tujuan studi ini untuk mengetahui prevalensi PD-L1 pada pasien kanker paru untuk melihat cakupan penggunaan PD-1 inhibitor. Studi ini ialah studi deskriptif observasional dengan desain potong lintang, dan bertempat di Laboratorium Patologi Anatomi MRCCC Siloam Hospitals Semanggi, Jakarta Selatan. Variabel yang diteliti ialah jenis kelamin, usia, jenis kanker paru, dan hasil pemeriksaan imunohistokimia PD-L1 Sp263 pada pasien kanker paru pada tahun 2020 – 2023. Hasil studi mendapatkan jumlah pasien kanker paru yang memeriksakan PD-L1 Sp263 sebanyak 161 pasien yang terdiri atas 100 pasien laki-laki (62,1%) dan 61 pasien perempuan (37,9%). Rentang usia pasien 30-85 tahun dengan rata-rata 61,49 (SD + 10,68), dan prevalensi paling tinggi pada pasien > 60 tahun (57,1%). Jenis kanker paru terbanyak ialah adenokarsinoma (76,4%). Prevalensi PD-L1 positif ditemukan pada 71 (44,1%) pasien, terdiri atas 48 (29,8%) pasien positif rendah dan 23 (14,3%) pasien positif tinggi. Prevalensi PD-L1 pada pasien kanker paru dalam studi masih cukup tinggi sehingga memberikan harapan untuk pasien mendapatkan imunoterapi (PD-L1 inhibitor).
DETEKSI DINI GANGGUAN PROSTAT MELALUI EDUKASI DAN SKRINING PSA PADA KOMUNITAS LANSIA GEREJA ASISI JAKARTA Sugiharto, Sony; Santoso, Alexander Halim; Raharjo, Budiarjo Notonagoro; Hardjanto, Kevin Shen Angga; Firmansyah, Yohanes
Jurnal Bakti Masyarakat Indonesia Vol. 8 No. 1 (2025): Jurnal Bakti Masyarakat Indonesia
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jbmi.v8i1.34383

Abstract

Abstract Prostate disorders, including benign prostatic hyperplasia (BPH) and prostate cancer, represent important health issues among elderly men. Public awareness of the importance of early detection remains low, especially among the elderly. This community service initiative aimed to raise awareness among the elderly about the importance of early detection of prostate disorders through educational seminars and prostate-specific antigen (PSA) screening. The activity was conducted in the community of Asisi Church, Jakarta, involving 105 participants, consisting of 26 men and 79 women. The educational seminar was delivered interactively, covering topics such as prostate anatomy, symptoms, and the importance of screening. Following the seminar, PSA screening using a venous blood-based rapid test was carried out for eligible male participants. The screening results revealed that all male participants (100%) had PSA levels within the normal range. This program successfully enhanced participants and their family understanding of prostate health and encouraged active community involvement in health promotion and disease prevention. It is recommended that such programs be implemented continuously with a more personalized and collaborative approach to reach a broader at-risk population and facilitate appropriate referral for participants with abnormal findings. Abstrak Gangguan prostat, baik benign prostatic hyperplasia (BPH) maupun kanker prostat, merupakan masalah kesehatan yang penting pada laki-laki lanjut usia. Kesadaran masyarakat terhadap pentingnya deteksi dini masih rendah, terutama di kalangan lansia. Kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan kesadaran lansia mengenai pentingnya deteksi dini gangguan prostat melalui seminar edukasi dan skrining prostate-specific antigen (PSA). Kegiatan dilaksanakan di lingkungan Gereja Asisi Jakarta dan melibatkan 105 peserta, terdiri dari 26 laki-laki dan 79 perempuan. Seminar edukasi disampaikan secara interaktif dengan materi seputar anatomi prostat, gejala, serta pentingnya skrining. Setelah edukasi, dilakukan skrining PSA menggunakan metode rapid test berbasis darah vena kepada peserta laki-laki yang memenuhi kriteria. Hasil skrining menunjukkan bahwa seluruh peserta laki-laki (100%) memiliki kadar PSA dalam rentang normal. Kegiatan ini berhasil meningkatkan pemahaman peserta dan keluarganya terhadap pentingnya pemeriksaan kesehatan prostat dan mendorong partisipasi aktif komunitas dalam upaya promosi kesehatan dan pencegahan penyakit tidak menular. Saran agar program ini dilaksanakan secara berkesinambungan dengan pendekatan lebih personal dan kolaboratif agar menjangkau lebih banyak populasi berisiko serta mendorong rujukan lebih lanjut bagi peserta dengan hasil abnormal.