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PENINGKATAN KESEHATAN MASYARAKAT MELALUI PENGENALAN DIVERSIFIKASI PRODUK NUTRASETIKAL DI DESA BUNDER JAWA BARAT Fathurohman, Mochamad; Pratita, Anindita Tri Kusuma; Wardani, Gatut Ari; Setiawan, Fajar; Lestari, Tresna; Nofianti, Tita; Ruswanto, Ruswanto; Nurviana, Vera; Rahmiyani, Ira; Nurdianti, Lusi
JMM (Jurnal Masyarakat Mandiri) Vol 5, No 4 (2021): Agustus
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v5i4.5113

Abstract

Abstrak: Tujuan pengabdian kepada masyarakat ini untuk memberikan informasi tentang pangan fungsional dan suplemen makanan serta memperkenalkan contoh produknya yaitu susu kedelai berbasis mikroalga. Metode kegiatan dalam bentuk sosialisasi dengan cara diskusi dan pembagian produk. Sasaran kepada masyarakat terutama ibu rumah tangga dengan jumlah yang hadir 43 orang. Untuk mengetahui pemahaman peserta dilakukan evaluasi dalam bentuk kuisioner sertatanya jawab terkait materi yang disampaikan. Hasil yang telah dicapai bahwa peserta dapat meningkatkan pengetahuan terkait produk nutrasetikal dengan presentase rerata 80-90%, serta diharapkan dapat membuat atau mengembangkan inovasi produk lainnya. Abstract: This community service aims to provide information about functional foods and food supplements and introduce microalgae based soy milk products. Methods in socialization activities by discussion and product distribution. The target for the community, especially recitation participants, with the number of people attending, is about 43 people. To find out the understanding of the evaluation participants in the form of questionnaires and questions and answers related to the material presented. The results can increase knowledge related to nutraceutical products with a precented of 80-90%, and create or develop other product innovations. 
ANALISIS KADAR SERAT PATI TERMODIFIKASI LENTIL MERAH DAN LENTIL HITAM Pratita, Anindita Tri Kusuma; Meri, Meri; Fathurohman, Mochamad
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 21, No 2 (2021)
Publisher : STIKes Bakti Tunas Husada Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v21i2.747

Abstract

PENYULUHAN PENCEGAHAN PENYAKIT PASCA BANJIR DENGAN MENERAPKAN POLA PHBS DI DUSUN RANGKASAN Pratita, Anindita Tri Kusuma; Mabruro, *De Hiban Fauzan; Bahri, Heri Syaiful; Amrullah, Muhammad Muzaki Fikri; Rabbani, Dzilla Fadillah; Fauziah, Siska Rahmatul; Jenika, Vika; Fathurohman, Mochamad
Kumawula: Jurnal Pengabdian Kepada Masyarakat Vol 6, No 3 (2023): Kumawula: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/kumawula.v6i3.47787

Abstract

Bencana banjir yang terjadi di Dusun Rangkasan, Desa Tarisi, Kecamatan Wanareja menyebabkan timbulnya penyakit pasca banjir yang dialami oleh masyarakat. Penyakit pasca banjir adalah suatu penyakit yang timbul setelah terjadinya bencana banjir diantaranya penyakit kulit (kurap), diare, demam dan lainnya yang terjadi apabila turunnya hujan deras setiap tahun, yang mengakibatkan air sungai meluap. Penelitian ini bertujuan untuk mengetahui perbandingan tingkat pengetahuan dan memberikan kontribusi dalam pemahaman masyarakat Dusun Rangkasan mengenai cara penanggulangan terhadap penyakit pasca banjir dengan menerapkan pola PHBS. Metode dalam penelitian ini menggunakan One Group Pretest Posttest Design dengan menganalisis data secara Deskriptif. Hasil yang didapatkan dengan adanya perbandingan usia, yaitu antara usia 22-27 tahun diperoleh nilai persentase tertinggi 30,43478 %. Sedangkan hasil dengan perbandingan pendidikan terakhir terdapat dalam pendidikan SMP dengan nilai persentase tertinggi 56,5 %.  Dapat disimpulkan terdapat 23 responden yang menghadiri penyuluhan ini dengan adanya perubahan signifikan sangat mempengaruhi terhadap data hasil perbandingan tingkat pengetahuan antar usia dengan pendidikan terakhir berdasarkan pengetahuan sebelum dan sesudah penyampaian materi. The flood disaster that occurred in Rangkasan Hamlet, Tarisi Village, Wanareja District caused the emergence of post-flood diseases experienced by the community. Post-flood disease is a disease that arises after a flood disaster, including skin diseases (ringworm), diarrhea, fevers, and others that occur when there is heavy rain every year, which causes river water to overflow. This study aims to compare the level of knowledge and contribute to the understanding of the people of Rangkasan Hamlet regarding how to deal with post-flood diseases by applying the PHBS pattern. The method in this study used the One Group Pretest Posttest Design by analyzing the data descriptively. The results obtained by comparison of age, namely between the ages of 22-27 years, obtained the highest percentage value of 30.43478%. While the results with the last comparison of education are in junior high school education with the highest percentage value of 56.5%. It can be concluded that there were 23 respondents who attended this counseling with a significant change that greatly affected the data resulting from a comparison of knowledge levels between ages and recent education based on knowledge before and after delivering the material.Bencana banjir yang terjadi di Dusun Rangkasan, Desa Tarisi, Kecamatan Wanareja menyebabkan timbulnya penyakit pasca banjir yang dialami oleh masyarakat. Penyakit pasca banjir adalah suatu penyakit yang timbul setelah terjadinya bencana banjir diantaranya penyakit kulit (kurap), diare, demam dan lainnya yang terjadi apabila turunnya hujan deras setiap tahun, yang mengakibatkan air sungai meluap. Penelitian ini bertujuan untuk mengetahui perbandingan tingkat pengetahuan dan memberikan kontribusi dalam pemahaman masyarakat Dusun Rangkasan mengenai cara penanggulangan terhadap penyakit pasca banjir dengan menerapkan pola PHBS. Metode dalam penelitian ini menggunakan One Group Pretest Posttest Design dengan menganalisis data secara Deskriptif. Hasil yang didapatkan dengan adanya perbandingan usia, yaitu antara usia 22-27 tahun diperoleh nilai persentase tertinggi 30,43478 %. Sedangkan hasil dengan perbandingan pendidikan terakhir terdapat dalam pendidikan SMP dengan nilai persentase tertinggi 56,5 %.  Dapat disimpulkan terdapat 23 responden yang menghadiri penyuluhan ini dengan adanya perubahan signifikan sangat mempengaruhi terhadap data hasil perbandingan tingkat pengetahuan antar usia dengan pendidikan terakhir berdasarkan pengetahuan sebelum dan sesudah penyampaian materi. Kata Kunci: Penyakit Pasca Banjir; PHBS; Usia; Pendidikan Terakhir
The Potency of Alkaloid Derivates as Anti-Breast Cancer Candidates: In Silico Study Renadi, Sedin; Pratita, Anindita Tri Kusuma; Mardianingrum, Richa; Ruswanto, Ruswanto
Jurnal Kimia Valensi Jurnal Kimia VALENSI Volume 9, No. 1, May 2023
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v9i1.31481

Abstract

Breast cancer is the most frequent malignancy in women worldwide. One of the target receptors for the treatment of breast cancer are estrogen, progesterone, and HER2 receptors. An alternative treatment using natural ingredients has been developed, one of which is alkaloid compounds. This study aims to determine the activity of alkaloid compounds as anti-breast cancer agents through an in-silico method. Virtual screening (AutoDock Vina), molecular docking (AutoDock Tools), molecular dynamics (Desmond), scanning Lipinski's rule of five, as well as pharmacokinetic and toxicity parameters, were performed. The results of virtual screening, molecular docking, and molecular dynamics show that the compounds daurisoline, solasodine, and sambutoxin have stable interactions with the HER2 receptor, with the lowest values of RMSD (Root Mean Square Deviation) and RMSF (Root Mean Square Fluctuation) compared to other compounds. Based on the results of the study conducted, it was shown that daurisoline, solasodine, and sambutoxin were predicted to be used as anti-HER2 candidates for the treatment of breast cancer.
Radiolabeling and In-Silico Study of 131I-(4-fluorobenzoyl-3-methylthiourea) as Radiopharmaceuticals for Breast Cancer Theranostics Pratama, Febby; Ruswanto, Ruswanto; Nofianti, Tita; Pratita, Anindita Tri Kusuma; Daruwati, Isti; Susilo, Veronika Yulianti; Holik, Holis Abdul
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 1, May 2024
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i1.34258

Abstract

The chemicals produced from thiourea are actively being studied as anticancer possibilities. In complexes with radionuclides like Iodine-131, the 1-(4-Fluorobenzoyl)-3-methyl thiourea is a promising ligand for theragnostic applications. This study aimed to label 1-(4-fluorobenzoyl-3-methylthiourea) with iodine-131 and observe its interaction with breast cancer receptors. The radiolabeling of 131I-(4-fluorobenzoyl-3-methylthiourea) uses the radioiodination method with Chloramine-T, and an in-silico investigation of breast cancer receptors was conducted. According to the results of molecular docking using AutoDockTools, this radiopharmaceutical molecule has the best activity on the HER2 receptor (PDB ID: 3PP0) compared to the native ligand and control positive, with a binding affinity of -6.13 kcal/mol and a Ki value of 32.05 mM. According to the molecular dynamics data using Desmond, the radiopharmaceutical molecule 131I-(4-Fluorobenzoyl-3-methylthiourea) displays good stability starting from the 50ns range. The indirect radioiodination method has successfully labeled 1-(4-Fluorobenzoyl-3-methylthiourea) with iodine-131.
PENINGKATAN PENGETAHUAN MASYARAKAT TENTANG PENYAKIT DEMAM BERDARAH DENGUE MELALUI PENYULUHAN DI PROVINSI JAWA BARAT Pratita, Anindita Tri Kusuma; Octavia, Diva Rachma; Mutiarani, Sri Sentia; Putra, Gusti Teguh Dwi; Ramadan, Rima Sonia; Nurazizah, Rifah
JMM (Jurnal Masyarakat Mandiri) Vol 8, No 5 (2024): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v8i5.25452

Abstract

Abstrak: Kasus DBD cenderung meningkat setiap tahunnya. Berdasarkan observasi awal, mayoritas masyarakat Desa Cayur, terutama kalangan lansia, belum sepenuhnya menyadari gejala awal DBD dan cara penanganan yang tepat. Oleh sebab itu, dilakukan program penyuluhan dengan tujuan memberikan edukasi yang mendalam mengenai DBD, sehingga masyarakat lebih siap dan mampu melakukan tindakan pencegahan yang efektif. Sistem evaluasi yang digunakan dalam pengabdian berikut yaitu One Group Pretest Postest Design dengan responden masyarakat cayur sebanyak 39 orang. Rata-rata nilai pretest yang semula 58.97 meningkat menjadi 83.33 pada posttest, menunjukkan peningkatan sebesar 24.36 poin. Data ini menunjukkan bahwa penyuluhan berhasil meningkatkan pengetahuan peserta secara signifikan. Berdasarkan hasil pengolahan data menggunakan SPSS, penyuluhan yang komprehensif dapat meningkatkan pengetahuan dan kesadaran masyarakat tentang penyakit DBD.Abstract: DHF cases tend to increase every year. Based on initial observations, the majority of the Cayur Village community, especially the elderly, are not fully aware of the early symptoms of dengue fever and the appropriate treatment methods. Therefore, an outreach program was carried out with the aim of providing in-depth education about dengue fever, so that the community is better prepared and able to take effective preventive measures. The evaluation system used in the following service is One Group Pretest Posttest Design with 39 cayur community respondents. The average pretest score which was originally 58.97 increased to 83.33 in the post test, showing an increase of 24.36 points. This data shows that the extension succeeded in increasing participants' knowledge significantly. Based on the results of data processing using SPSS, comprehensive education can increase public knowledge and awareness about dengue fever. 
Radiolabeling and In-Silico Study of 131I-(4-fluorobenzoyl-3-methylthiourea) as Radiopharmaceuticals for Breast Cancer Theranostics Pratama, Febby; Ruswanto, Ruswanto; Nofianti, Tita; Pratita, Anindita Tri Kusuma; Daruwati, Isti; Susilo, Veronika Yulianti; Holik, Holis Abdul
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 1, May 2024
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i1.34258

Abstract

The chemicals produced from thiourea are actively being studied as anticancer possibilities. In complexes with radionuclides like Iodine-131, the 1-(4-Fluorobenzoyl)-3-methyl thiourea is a promising ligand for theragnostic applications. This study aimed to label 1-(4-fluorobenzoyl-3-methylthiourea) with iodine-131 and observe its interaction with breast cancer receptors. The radiolabeling of 131I-(4-fluorobenzoyl-3-methylthiourea) uses the radioiodination method with Chloramine-T, and an in-silico investigation of breast cancer receptors was conducted. According to the results of molecular docking using AutoDockTools, this radiopharmaceutical molecule has the best activity on the HER2 receptor (PDB ID: 3PP0) compared to the native ligand and control positive, with a binding affinity of -6.13 kcal/mol and a Ki value of 32.05 mM. According to the molecular dynamics data using Desmond, the radiopharmaceutical molecule 131I-(4-Fluorobenzoyl-3-methylthiourea) displays good stability starting from the 50ns range. The indirect radioiodination method has successfully labeled 1-(4-Fluorobenzoyl-3-methylthiourea) with iodine-131.