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The Effects of Beta-Ionone Addition in Perfume on Behavior and Serum Cortisol Level of Stress-Induced Mice Budiman, Clarissa; Miatmoko, Andang; Tyas, Veronika Earline Pudji Setianing; Ardianto, Chrismawan; Retnowati, Dini
Science and Technology Indonesia Vol. 9 No. 2 (2024): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.2.470-479

Abstract

Stress is a condition that triggers a change in behavior and physiological state, affecting mental health. Beta-Ionone is a monocyclic terpenoid compound that can lower stress levels. However, there is a lack of studies about the anti-stress capability of Beta-Ionone inhalation, although Beta-Ionone is commonly used as a fragrance in perfumes. This study aimed to evaluate the effect of Beta-Ionone addition as the fragrance in perfumes on mice stress. The Beta-Ionone perfume was formulated with Bergamot Oil, Lavender Oil, Eucalyptus Oil, Tea Tree Oil, and Patchouli Oil to produce Fem, Fem-Ion (Fem + Beta-Ionone), Masc, and Masc-Ion (Fem + Beta-Ionone), which had different preferable odors. The anti-stress effectivity was then evaluated in stress induced mice, which were restrained for one hour every day for one week. The perfumes were then given by inhalation every alternate day. The stress level of the mice was evaluated using a tail suspension test and serum cortisol level assays. The results showed that inhalation of the perfumes lowered the immobility time of mice in the tail suspension test, albeit the addition of Beta Ionone did not give a significant difference. Based on the results of serum cortisol level, there was a substantial decrease in serum cortisol by inhaling the Fem and Fem-Ion, showing decreases in stress level. However, there were increases in serum cortisol levels for Masc and Masc-Ion, indicating stress induction, which was suggested to be caused by 1,8-cineole, a compound in the Eucalyptus oil as the perfume oil components.
Lecture Presentations Combined with Comic Story-Telling to Increase the Knowledge and Understanding of Elementary and Junior High School Students about Drugs Concerning Self-Medication Behavior Miatmoko, Andang; Mufariha, Mufariha; Retnowati, Dini; Paramanandana, Abhimata; Sugiyartono, Sugiyartono; Sari, Retno; Purwanti, Tutiek; Isadiartuti, Dewi; Hendradi, Esti
Journal of Community Research and Service Vol 6, No 2: July 2022
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jcrs.v6i2.35665

Abstract

Self-medication practice can result in medication errors due to limited public knowledge of pharmaceutical medicine, especially among school-aged adolescents, who are prohibited from doing self-medication. This study aimed to evaluate the students' knowledge and understanding of pharmaceutical medicine, pharmacists, and self-medication, and also the awareness to be wise and smart in responding to the use of pharmaceutical products for maintaining public health. The study was carried out by conducting the lecture on drugs and self-medication through a classical presentation and comic story to students of SDN Keputih 245 Elementary School and SMPN 19 Junior High School, Surabaya. Moreover, DAGUSIBU dance was also practiced. The students actively engaged in the class during the presentation. The results of the pre-and post-test evaluations showed that this lecture method had succeeded in increasing junior high school students' knowledge about medicine and DAGUSIBU. On the other hand, the pre-test scores of Elementary School students were better than the post-test, except for new knowledge related to the drug logo and classification. It suggests that the delivery methods were inappropriate for elementary school students. It can be concluded that school-age adolescents, especially in elementary and junior high schools, need assistance during self-medication. This community service activity by a presentation and comic telling methods successfully improved the knowledge of SMPN 19 Junior High School about drugs and DAGUSIBU; however, it needs a more straightforward explanation with attractive learning methods for delivering a lecture to Elementary School students.
Characterization and Stability Test of Hydrolyzed Collagen Glyserosomes Safiul Fitria, Nur Indah; Erawati, Tristiana; Miatmoko, Andang; Soeratri, Widji
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 11 No. 1 (2024): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v11i12024.71-79

Abstract

Background: Hydrolyzed collagen is a protein obtained from enzymatic denaturation of collagen with a molecular weight of about 10 kDa, and it has been reported to produce anti-aging properties. Delivering hydrolyzed collagen into the dermis becomes a great challenge due to its large molecular weight, so glycerosome, a deformable vesicle containing glycerol as the edge activator, was developed to carry it into the dermis layer. Objective: The study aimed to determine the effect of increasing the concentration of glycerol and hydrolyzed collagen on the characteristics and stability of hydrolyzed collagen glycerosomes. Methods: Glycerosomes were composed of soy lecithin and prepared using a thin film lipid method. The lipid film was hydrated with phosphate-buffered saline pH 5 containing different glycerol concentrations (20% and 40%) and hydrolyzed collagen (2.5% and 5%). Then, characteristic tests and stability tests were carried out. Results: Hydrolyzed collagen glycerosomes had vesicle sizes of 170-180 nm, polydispersity index of 0.253-0.279, zeta potential values of -23.70 to -26.50 mV with deformability indexes of 2.25-3.49. The highest percentage of entrapment efficiency was 85.72%, achieved with a glycerol concentration of 40%. During the stability test at 25°C for 12 weeks, the hydrolyzed collagen glycerosomes did not experience pH and entrapment efficiency changes, but it increased the vesicle size. Conclusion: The use of 40% glycerol produced more deformable vesicles than 20% glycerol in hydrolyzed collagen glycerosomes; however, a formula improvement is required to improve the stability of glycerosomes.
Peningkatan Nilai Guna Limbah Kulit Jeruk Nipis melalui Produk Sederhana Guna Mendukung SDGs bagi Petani Jeruk di Kecamatan Ujung Pangkah, Gresik Sari, Retno; Hendradi, Esti; Rijal, Agus Syamsur; Retnowati, Dini; Suzana, Suzana; Ramadhani, Firmansyah Ardian; Miatmoko, Andang; Sulistyowati, Melanny Ika; Sukardiman, Sukardiman; Ekowati, Juni
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 1 (2025): Volume 8 No 1 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i1.18244

Abstract

ABSTRAK Permasalahan di Desa Bolo Ujung Pangkah Gresik produksi jeruk nipis yang tinggi/melimpah. Sehingga harga jual menjadi rendah dan banyak produk panen tidak dapat terserap oleh pasar. Selain itu limbah kulit jeruk nipis yang terbuang juga akan meningkat. Hal ini akan mengakibatkan kerugian bagi petani. Permasalahan tersebut akan dibantu dengan kegiatan pengabdian kepada masyarakat dengan tujuan untuk menambah pengetahuan masyarakat dengan meningkatkan nilai guna limbah jeruk nipis di kecamatan Ujung Pangkah, Gresik, khususnya di desa Bolo melalui pengolahan produk berbahan ekstrak kulit jeruk nipis. Hal ini sesuai dengan tujuan Sustainable Development Goals (SDGs) 12 yaitu pemanfaatan sumber daya alam yang efisien. Kegiatan pengabdian masyarakat diawali dengan pre-test yang dilanjutkan dengan pemaparan materi dan demo pembuatan produk micellar water dan hand sanitizer dari ekstrak kulit jeruk. Selanjutnya dilakukan post-test untuk mengukur perubahan pengetahuan peserta setelah pelatihan. Berdasarkan hasil pre-test dan post-test terdapat peningkatan kemampuan dan pengetahuan peserta tentang khasiat bahan yang terkandung dari kulit jeruk. Peserta dapat meningkatkan nilai guna dari limbah kulit jeruk nipis dalam bentuk produk sederhana kaya manfaat seperti micellar water dan hand sanitizer dari kulit jeruk nipis. Kata Kunci: Kulit Jeruk Nipis, Micellar Water, Hand Sanitizer, SDGs 12  ABSTRACT The problem in Bolo Ujung Pangkah Gresik Village is the high/abundant production of limes. So that the selling price is low and many harvested products cannot be absorbed by the market. In addition, the waste of lime peels that are thrown away will also increase. This will result in losses for farmers. The problem will be helped by community service activities with the aim of increasing public knowledge by increasing the utility value of lime waste in Ujung Pangkah sub-district, Gresik, especially in Bolo village through processing products made from lime peel extract. This is in accordance with the objectives of Sustainable Development Goals (SDGs) 12, namely efficient utilization of natural resources. Community service activities began with a pre-test followed by a presentation of materials and a demonstration of making micellar water and hand sanitizer products from orange peel extract. A post-test was then conducted to measure changes in participants' knowledge after the training. Based on the results of the pre-test and post-test, there was an increase in participants' abilities and knowledge about the properties of the ingredients contained in lime peel. Participants can increase the utility value of lime peel waste in the form of simple, beneficial products such as micellar water and hand sanitizer from lime peel. Keywords: Lime Peel, Micellar Water, Hand Sanitizer, SDGs 12
PELATIHAN DISPENSING ASEPTIK SEDIAAN STERIL DI LAYANAN KESEHATAN KOTA MAKASSAR CITY DAN SEKITARNYA: Training on Aseptic Dispensing of Sterile Preparations in The Health Services of Makassar and Surroundings Isadiartuti, Dewi; Sari, Retno; Rijal, Muh. Agus Syamsur; Ratri, Dinda Monika Nusantara; Retnowati, Dini; Rudyanto, Marcellino; Miatmoko, Andang
JAMAS : Jurnal Abdi Masyarakat Vol. 3 No. 1 (2025)
Publisher : Forind Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62085/jms.v3i1.172

Abstract

Sediaan steril adalah sediaan yang tidak boleh mengandung mikroorganisme, partikel, serta sedapat mungkin dibuat isotonis. Kondisi steril tersebut harus dapat dijamin oleh apoteker sampai sediaan digunakan oleh pasien. Salah satu jenis pelayanan kefarmasian yang dilakukan oleh apoteker di fasilitas kesehatan adalah disepensing sediaan steril. Proses dispensing sediaan steril memerlukan teknik aseptis. Teknik aseptis merupakan salah satu aspek penting yang perlu diperhatikan oleh apoteker dalam menjalankan praktik kefarmasian khususnya di rumah sakit. Makassar yang merupakan ibukota Provinsi Sulawesi Selatan merupakan kota keempat terbesar di Indonesia. Kota Makassar merupakan tempat tinggal bagi lebih dari 15% penduduk Provinsi Sulawesi Selatan. Jumlah penduduk yang terus meningkat dan kualitas sumber daya yang baik sangat berguna untuk mendorong pertumbuhan ekonomi. Namun, jika tidak didukung dengan sumber daya manusia yang berkualitas, masalah sosial di Kota Makassar akan semakin meningkat. Salah satu cara dalam meningkatkan sumber daya manusia dapat melalui pengabdian masyarakat. Tujuan dari pengabdian masyarakat adalah untuk meningkatkan pengetahuan serta ketrampilan apoteker dalam hal dispensing aseptik sediaan steril di layanan kesehatan Kota Makassar dan sekitarnya. Kegiatan dilaksanakan di Auditorium Universitas Islam Makassar pada hari Sabtu 19 Oktober 2024 diikuti 34 peserta apoteker dari Rumah Sakit dan Puskesmas yang melakukan layanan pengelolaan sediaan steril. Dari hasil pre/post test tentang materi yang diberikan dan evaluasi kegiatan menunjukkan peningkatan pemahaman peserta dan respon positif terhadap pelatihan yang diselenggarakan oleh tim pengabdian masyarakat Fakultas Farmasi Universitas Airlangga. Harapan peserta pelatihan di masa mendatang kegiatan diperbanyak dan alokasi waktu pelaksanaan dapat lebih diperpanjang.
Pelatihan inovasi produk berbahan kulit buah manggis sebagai upaya peningkatan perekonomian masyarakat Desa Songgon Kabupaten Banyuwangi Suciati, Suciati; Ekasari, Wiwied; Miatmoko, Andang; Purwitasari, Neny; Hasib, Fatin Fadhilah; Ilmi, Hilkatul; Wicaksana, Firman; Haula, Hamizah
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 2 (2025): March
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i2.28952

Abstract

Abstrak Desa Songgon adalah salah satu desa di Kabupaten Banyuwangi yang dikembangkan sebagai desa wisata. Desa ini memiliki kekayaan alam yang melimpah terutama buah manggis sebagai komoditas unggulan. Masyarakat Desa Songgon memanfaatkan buah manggis untuk konsumsi sehari-hari dan dijual. Harga buah manggis di pasaran sangat fluktuatif terutama saat musimnya harganya sangat murah.  Permasalahan lain yang dihadapi adalah dari kulit buah manggis yang kerap kali hanya menjadi limbah rumah tangga. Oleh karena itu perlu adanya program peningkatan pengetahuan dan keterampilan terkait pengolahan kulit buah manggis menjadi berbagai produk berdaya jual serta strategi pemasarannya kepada warga Desa Songgon. Metode yang dilakukan berupa penyuluhan dan praktek pembuatan produk kepada kader PKK dan karang taruna Desa Songgon. Hasil dari kegiatan ini adalah meningkatnya pengetahuan peserta dilihat dari kenaikan nilai pre-test 54,9 menjadi 83,9 pada post-test. Peserta juga mendapatkan keterampilan dalam pembuatan teh celup dan sabun antibakteri dengan bahan dasar kulit buah manggis.  Hasil uji aktivitas antioksidan dari teh celup mangostana dan mangostana mix yang dibuat menunjukkan bahwa produk teh yang dibuat memiliki aktivitas antioksidan yang baik. Pengetahuan dan keterampilan yang diperoleh kader PKK dan Karang Taruna diharapkan dapat diimplementasikan dalam kehidupan sehari-hari. Peserta belajar bagaimana membuat produk inovatif dari buah manggis sehingga dapat diproduksi secara komersial. Dengan demikian, dalam jangka panjang diharapkan dapat meningkatkan pendapatan masyarakat Desa Songgon. Kata kunci: Desa Songgon; Banyuwangi; buah manggis; inovasi produk. Abstract Songgon Village is one of the villages in Banyuwangi Regency that is developed as a tourist village. This village is rich in natural resources, with mangosteen being one of the most valuable commodities. The people of Songgon Village use mangosteen for daily consumption and for trade. The price of mangosteen on the market is very fluctuating, especially during mangosteen season, it is very cheap. Another issue faced is the mangosteen rind often becomes household waste. The purpose of this community service is to enhance the knowledge and skills of the residents of Songgon Village regarding the processing of mangosteen rind into a variety of innovative health products as well as the marketing strategy of the product. The method used is counseling and practices for PKK cadres and youth organizations of Songgon Village. The results of this program showed that there was an increase in the knowledge of participants according to the pre-test score (54,9) to 83,9 in post-test. Participants also gain the skill in making tea and soap from mangosteen rinds. The antioxidant activity of the tea products, mangostana and mangostana mix, showed good antioxidant activity of the tea infusion. The knowledge and skill gain by participants related innovative products from mangosteen fruit can be implemented, so that they can be produced commercially. Thus, in the long term it is expected to increase the income of the Songgon Village residents. Keywords: Songgon Village; Banyuwangi; mangosteen; innovative products.
PERAN STRATEGIS PKK DALAM MENUNJANG PENINGKATKAN PEMAHAMAN MASYARAKAT TENTANG OBAT DAN SUPLEMEN MAKANAN Hendradi, Esti; Sari, Retno; Purwanti, Tutiek; Erawati, Tristiana; Miatmoko, Andang; Sugiyartono, Sugiyartono
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 2 (2025): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i2.28739

Abstract

Abstrak: Pemahaman masyarakat tentang obat termasuk cara mendapatkan, menggunakan, menyimpan dan membuang serta penggunaan suplemen makanan masih perlu mendapat perhatian khusus, terutama untuk masyarakat perifer. Peran apoteker dibutuhkan dalam mengedukasi masyarakat dengan melibatkan gerakan Pemberdayaan dan Kesejahteraan Keluarga (PKK). Tujuan PKM ini adalah meningkatkan pengetahuan tentang obat dan suplemen makanan kepada masyarakat dengan memberdayakan PKK. Tim pengabdian kepada masyarakat Fakultas Farmasi Universitas Airlangga telah menyelenggarakan kegiatan bakti sosial bersama-sama IAI dan kader PKK di Kota Madya Tuban dalam bentuk penyuluhan atau sosialisasi terkait obat dan suplemen makanan. Sosialisasi dilakukan melalui Webinar via Zoom Meeting dalam bentuk seminar dan diskusi interaktif, karena aktivitas pengabdian dilaksanakan saat pandemi Covid-19. Sebagai mitra pada pengabdian masyarakat ini adalah Kader PKK dan Ketua Ikatan Apoteker Indonesia (IAI) Cabang Tuban dengan jumlah peserta yang hadir sejumlah 71 orang. Hasil evaluasi melalui pre-test dan post-test menunjukkan bahwa setelah mengikuti kegiatan rerata pemahaman peserta meningkat 7,04% dan 12,7% masing-masing untuk materi DAGUSIBU dan Probiotik. Diharapkan PKK secara aktif menyebar-luaskan kegiatan sosialisasi kepada masyarakat di seluruh desa.Abstract: Public understanding of medicines, including how to obtain, use, store and dispose of them as well as the use of food supplements, still needs special attention, especially for peripheral communities. The role of pharmacists is needed in educating the public by involving the Family Empowerment and Welfare (PKK) movement. The aim of this PKM is to increase knowledge about medicines and food supplements among the community by empowering PKK. The community service team at the Faculty of Pharmacy, Airlangga University has held social service activities together with IAI and PKK cadres in Tuban in the form of counseling or outreach regarding medicines and food supplements. Socialization was carried out through Webinar via Zoom Meeting in the form of seminars and interactive discussions, because service activities were carried out during the Covid-19 pandemic. As partners in this community service were PKK cadres and the Chair of the Indonesian Pharmacists Association (IAI) in Tuban city with a total of 71 participants attending. The evaluation results via pre-test and post-test showed that after participating in the activity the participants' average understanding increased by 7.04% and 12.7% for DAGUSIBU and Probiotic material, respectively. It is hoped that the PKK will actively spread outreach activities to communities throughout the village.