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Journal : Indonesian Journal of Global Health research

Formulation and Physical Assessment of Different Topical Products using Bandotan Herb (Ageratum conyzoides L.) Extract Andriani, Disa; Pratimasari, Diah
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.4335

Abstract

Bandotan (Ageratum conyzoides L.) is one of the Asteraceae family plants that has bioactive compound components in the form of polyphenol compounds, terpenoids, and alkaloids. 70% ethanol extract of bandotan herb (Ageratum conyzoides L.) is known to have antioxidant activity. This makes herba bandotan has the potential to be develooped into cosmetic preparations to prevent premature aging of the skin. This study aims to determine the herba bandotan topical preparation that has the best physical properties. Bandotan herb was extracted with 70% ethanol in the amount of 1: 10 at 28˚C for 24 hours using the shaking method at 100 rpm. The ethanol liquid filtrate obtained was then evaporated to obtain a thick extract. Thick bandotan extract is then made into gel, cream, and lotion preparations and evaluated. The resulting % yield of bandotan herb extract was 11.3%. The concentration of 1%, 3% and 5% bandotan herb active substances in the preparation affects the organoleptics, viscosity, spreadability and adhesiveness of the preparation. The best topical preparations of bandotan herb extract that meet the requirements of the pH test, viscosity test, spreadability test, and adhesion test is cream preparations.
Formulation of Palmarosa (Cymbopogon Martinii) Essential Oil Emulgel Using Sodium Carboxymethyl Cellulose (Na-CMC) as A Gelling Agent Daniati, Odilia Putri; Andriani, Disa; Amin, Muhammad Saiful
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.6482

Abstract

Palmarosa essential oil (Cymbopogon martinii) is known for its potential as a natural therapeutic agent. It contains geraniol compounds with demonstrated antimicrobial and anti-inflammatory activity. However, direct application of palmarosa essential oil to the skin is less effective and may cause irritation. Objective: This study aimed to develop a topical formulation in the form of an emulgel containing palmarosa essential oil, using sodium carboxymethyl cellulose (Na-CMC) as the gelling agent. Method: The emulgel was prepared in three different formulations containing 2%, 4%, and 6% concentrations of palmarosa essential oil. The resulting preparations were evaluated for quality through organoleptic properties, homogeneity, pH, spreadability, adhesion, and emulsion type. Data were statistically analyzed using one-way ANOVA. Results: The emulsion type test indicated that all formulations were oil-in-water (o/w) emulsions. Differences in palmarosa essential oil concentration influenced the physical properties of the emulgel, but all three formulations met the standard requirements for good physical quality of emulgel preparations.Conclusions: the three emulgel formulations containing palmarosa essential oil fulfilled the standards for acceptable physical properties.