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PENGARUH EKSTRAK BUAH DELIMA MERAH TERHADAP KADAR SOD PADA KULTUR HUVECs YANG DIPAPAR PLASMA PREEKLAMPSI Januarsih, Januarsih
EMBRIO Vol 11 No 1 (2019): EMBRIO (MEI 2019)
Publisher : Program Studi S1 Kebidanan - Fakultas Sains dan Kesehatan Universitas PGRI Adi Buana Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (422.11 KB) | DOI: 10.36456/embrio.vol11.no1.a1801

Abstract

Preeklampsi merupakan sindroma yang berkaitan dengan adanya gejala vasospasme, peningkatan terhadap resistensi pembuluh darah perifer dan juga penurunan perfusi organ. Salah satu teori etiologi preeklampsi yang dianut saat ini mengatakan adanya ketidakseimbangan antara produksi radikal bebas dan sistem pertahanan antioksidan yang menyebabkan timbulnya stres oksidatif, ditandai dengan adanya penurunan aktivitas antioksidan disertai dengan adanya peningkatan kadar lipid peroksida (oksidan / radikal bebas). Keadaan ini tentu saja menimbulkan terganggunya fungsi endotel bahkan rusaknya seluruh struktur sel endotel yang disebut sebagai disfungsi endotel. Keadaan stres oksidatif bisa dikendalikan dengan pemberian anti oksidan yang terbagi dalam antioksidan enzimatis dan non enzimatis. Antioksidan enzimatis terdiri dari superoksida dismutase (SOD), glutation peroksidase dan katalase. Buah delima mengandung fitokimia dan kaya akan senyawa yang berfungsi sebagai antioksidan yaitu polifenol, tanin dan anthocyanin. Tujuan penelitian ini adalah untuk mengetahui efek pemberian ekstrak buah delima merah merah (Punica granatum) terhadap kadar SOD dan MDA pada kultur HUVECs yang dipapar plasma preeklampsi. Rancangan percobaan berupa rancangan acak lengkap dengan 5 kelompok perlakuan yaitu, Kelompok I : Kontrol negatif (K-) HUVECs + plasma kehamilan normal 2%, Kelompok II : Kontrol positif (K+) HUVECs + plasma preeklampsi 2%, Kelompok III : Perlakuan 1 (P1) HUVECs + plasma preeklampsi 2% + ekstrak buah delima merah 14 ppm, kelompok IV : Perlakuan 2 (P2) HUVECs + plasma preeklampsi 2% + ekstrak buah delima merah 28 ppm dan Kelompok V : Perlakuan 3 (P3) HUVECs + plasma preeklampsi 2% + ekstrak buah delima merah 56 ppm. Berdasarkan pada hasil uji LSD 5 % menunjukkan bahwa kelompok kontrol negatif (K-) memiliki rata-rata kadar SOD berbeda nyata dengan kelompok kontrol positif (K+) (p = < 0,05). Peningkatan kadar SOD secara signifikan ditunjukkan oleh pemberian ekstrak buah delima merah pada konsentrasi 56 ppm. Bahkan, pemberian ekstrak buah delima merah konsentrasi 56 ppm mampu meningkatkan kadar SOD hingga lebih tinggi daripada kelompok kontrol negatif (p = < 0,05), sedangkan pemberian ekstrak buah delima merah pada dengan konsentrasi 14 ppm dan 28 ppm, belum mampu meningkatkan kadar SOD secara signifikan (p = > 0,05). Sehingga dapat disimpulkan, bahwa pemberian ekstrak buah delima merah (Punica granatum) terbukti dapat meningkatkan kadar SOD pada kultur HUVECs yang dipapar plasma preeklampsi. Kata kunci : delima merah, SOD dan Preeklampsi
ENGLISH STUDY PADA MAHASISWA PROGRAM STUDI S1 KEBIDANAN UNIVERSITAS SARI MULIA BANJARMASIN Vebruati, Vebruati; Januarsih, Januarsih; Ahmad Rizani
Jurnal Pendidikan Dasar dan Sosial Humaniora Vol. 3 No. 7: Mei 2024
Publisher : Bajang Institute

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Abstract

This study is aimed at identifying and analyzing the needs of ESP learning material in learning English at diploma midwifery students. To find out the correct reference, needs analysis is urged to be done to obtain information about what the students really need to support their learning process at the present time or in the future career. This study was conducted by using qualitative approach and descriptive method. The samples were students from Midwifery Study Program of Sari Mulia University Banjarmasin who are currently taking English subject and the sampling technique used was purposive random sampling. Meanwhile, a questionnaire as the instrument for this study was arranged in closed-ended form. The data analysis was descriptive analysis in the form of number and percentage. The study revealed that the needs of nursing students on English subject are very diverse and it can be concluded that they need English not only for their current needs as they can communicate in English to support their education in nursing field, but also for their future professional career. Therefore, it is recommended that ESP English teachers or other related parties should accommodate the needs of these students. In addition, it is suggested to always conduct needs analysis since the needs of ESP learners are constantly changing
PROMOSI KESEHATAN TENTANG HIPERTENSI DAN DIABETES MELLITUS PADA LANSIA Rita Kirana; Tut Barkinah; Norlaila Sofia; Isnaniah, Isnaniah; Januarsih, Januarsih; Agus Rachmadi; Suhrawardi, Suhrawardi; Ahmad Rizani
JURNAL PENGABDIAN MANDIRI Vol. 3 No. 5: Mei 2024
Publisher : Bajang Institute

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Abstract

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Hubungan Pengetahuan dan Pekerjaan Dengan Pemberian ASI Eksklusif Di Wilayah Kerja Puskesmas Martapura I Tahun 2024 Fatimah, Siti; Hipni, Rubiati; Januarsih, Januarsih; Maslani, Noorhayati
JURNAL KEBIDANAN BESTARI Vol 8 No 01 (2024): Jurnal Kebidanan Bestari
Publisher : Midwifery Departement Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkb.v8i01.167

Abstract

Exclusive breastfeeding is giving breast milk to babies, without any other liquids or solids being given, even water, except for drops/syrup solutions of vitamins, minerals or medicines, exclusive breastfeeding is recommended until the child is 6 months old. To determine the factors associated with exclusive breastfeeding for babies aged 6-12 months in the Martapura I Community Health Center Work Area in 2024. Quantitative research type with a cross sectional design. A sample of 79 mothers who had babies aged 6-12 months used purposive sampling according to the researchers' criteria. The Independent Variables are Knowledge, Employment, Husband's Support, and Local Cultural Customs, while the Dependent Variable on Breastfeeding is data collection carried out by distributing questionnaires and conducting interviews with mothers who have babies aged 6-12 which contains information about the identity and knowledge of the respondents. The type of data in this research is nominal, which is analyzed through computerization. The results of the study showed that there was a relationship in all variables with exclusive breastfeeding. There were 79 samples, there were 20 (25.3%) respondents who succeeded in giving exclusive breast milk to their babies and 59 (74.7%) respondents who did not succeeded in giving exclusive breast milk to their babies. There is a relationship between Knowledge P value = 0.006, Occupation and P value = 0.001 with exclusive breastfeeding.Keywords: Exclusive breastfeeding, knowledge, work
PUNICA GRANATUM MENAIKKAN KADAR GLUTATHION PEROXYDASE PADA KULTUR HUVECs YANG DIPAPAR PLASMA PRE EKLAMPSI Januarsih, Januarsih; Fitria Jannatul Laili; Megawati, Megawati
Jurnal Cakrawala Ilmiah Vol. 4 No. 2: Oktober 2024
Publisher : Bajang Institute

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Abstract

Preeclampsia and Eclampsia rank as the number one cause of maternal death in Indonesia Preeclampsia is a syndrome associated with symptoms of vasospasm, increased peripheral vascular resistance and decreased organ perfusion. One of the current etiological theories of preeclampsia is that there is an imbalance between the production of free radicals and the antioxidant defense system that causes oxidative stress, characterized by a decrease in antioxidant activity accompanied by an increase in lipid peroxide levels (oxidants / free radicals). Oxidative stress can be controlled by administering anti-oxidants which are divided into enzymatic and non-enzymatic antioxidants. Enzymatic antioxidants consist of Superoxyd Dismutase (SOD), Glutathione peroxydase (GPx) and Catalase (Cat). Red pomegranate (Punica granatum) contains phytochemicals and is rich in compounds that function as antioxidants, namely polyphenols, tannins and anthocyanins. The purpose of this study was to determine the effect of red pomegranate (Punica granatum) extract on GPx levels in HUVECs cultures exposed to preeclamptic plasma. The research design was a complete randomized experimental design with 5 treatment groups. Red pomegranate extract is able to increase GPx levels because red pomegranate is rich in antioxidants. Red pomegranate (about 50% of the total weight of pomegranate) consists of 80% juice and 20% seeds. The juice itself contains 85% water, 10% sugar and 1.5% pectin, ascorbic acid and flavonoid polyphenols.
EDUKASI DAN PELATIHAN SENAM OTARIA SEBAGAI ASUHAN ESENSIAL PADA KELOMPOK IBU NIFAS DI WILAYAH KERJA PUSKESMAS KARANG INTAN 2 Januarsih, Januarsih; Rita Kirana; Ahmad Rizani
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 6: Nopember 2024
Publisher : Bajang Institute

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Abstract

The experience of being a parent is not always pleasant, especially being a mother. The reality is that the responsibility of motherhood often causes conflict within a woman. A postpartum woman needs physical and psychological adaptation in the first weeks after giving birth. In the adaptation process, some women manage to adapt well but others do not manage to adjust and experience psychological disorders with various symptoms or a syndrome called Baby Blues Syndrome. One of the efforts to prevent the occurrence of baby blues is by doing physical activity. Physical activity in the form of postpartum exercises that can be done immediately after delivery with movements that increase every day according to the mother's ability. Postpartum exercises with regularity can accelerate the recovery of physiological and psychological health status after childbirth. The most important physiological health recovery is the acceleration of healing of the uterus, abdomen, and hip muscles that have been traumatized and accelerate the return of these parts to their normal form. Psychologically, postpartum exercises can increase the mother's ability to deal with stress and relax so as to reduce postpartum depression. Based on aesthetic or beauty assessment, postpartum exercises will improve the elasticity of muscles that have been stretched, maintain good posture, and restore body slimness
EDUKASI DAN PENDAMPINGAN IBU HAMIL KEK PADA KELOMPOK IBU HAMIL DI DESA AWANG BANGKAL BARAT Suhrawardi, Suhrawardi; Januarsih, Januarsih; Isrowiyatun Daiyah
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 6: Nopember 2024
Publisher : Bajang Institute

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Abstract

If a pregnant woman experiences anemia and SEVERITY, she will be at risk during her pregnancy, childbirth and the baby that will be born. During pregnancy, pregnant women who experience anemia and SEVERITY are at risk of abortion, impaired growth of fetal brain cells, the distribution of nutrients from mother to fetus will also be severely disrupted, so that it will make the baby born potentially experience Low Birth Weight Babies (LBW) which if the condition is not handled will continue to stunting, fetal growth abnormalities and others. During childbirth, pregnant women who experience anemia and SEZ are at risk of bleeding during childbirth and in the last ten years, bleeding has always coexisted with Preeclampsia in the top two contributors to the Maternal Mortality Rate in Indonesia. Stunting in toddlers is influenced by maternal nutritional history such as chronic energy deficiency (CED) and iron nutritional anemia (AGB). The nutritional status of the mother before and during pregnancy can affect fetal growth. If the mother's nutritional status is normal before and during pregnancy, it is likely that she will give birth to a healthy, full-term baby with normal weight. Poor fetal growth of pregnant women with SEZ will result in low birth weight (LBW) babies. A pregnant woman will give birth to a healthy baby if her health and nutrition levels are in good condition
A, The Relationship Between Knowledge And Attitudes Of Adolescent Girls With The Dangers Of Pregnancy In Middle Adolescence At Smk Negeri 3 Banjarbaru In 2024 Anita, Nur; Januarsih, Januarsih; Maslani, Hj. Noorhayati; Rizani, Ahmad
JURNAL KEBIDANAN BESTARI Vol 8 No 2 (2024): Jurnal Kebidanan Bestari
Publisher : Midwifery Departement Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkb.v8i2.178

Abstract

Teenage pregnancy is a pregnancy that occurs in a woman under the age of 18 at the time the pregnancy ends. Pregnancy in adolescents can be dangerous if knowledge and attitudes are not monitored. To determine the Relationship between Knowledge and Attitudes of Adolescent Girls with the Dangers of Pregnancy in Middle Adolescence at SMK Negeri 3 Banjarbaru in 2024. This study used analytic observational research with a cross-sectional approach. The population in this study amounted to 153 respondents, who were taken by total sampling technique. The independent variables in the study were knowledge and attitude. The dependent variable in this study is the danger of pregnancy in adolescence. Collection and using a questionnaire. Data were analyzed using Spearman's Rho test with a significance of α = 0.05. The results showed that there was a significant relationship between knowledge and the dangers of pregnancy in middle adolescence (p=0.001; r= -0.256*). There is a significant relationship between attitude and the dangers of pregnancy in middle adolescence (p=0.004; r= -0.192**). The relationship obtained is a fairly strong relationship and the relationship between these variables is not unidirectional, meaning that the better the knowledge of adolescents, the danger of teenage pregnancy can be negative and also positive towards the danger of pregnancy in adolescence and the better the attitude of adolescents, the danger of teenage pregnancy can be negative and also positive towards the danger of pregnancy in adolescence. Keyword : Knowledge, Attitude, Danger Of Pregnancy In Middle Adolescence
Gentle Birth Untuk Persalinan Nyaman Pada Kelas Ibu Hamil Di Polindes Desa Awang Bangkal Rafidah, Rafidah; Isnaniah, Isnaniah; Rohmah, Nur; Januarsih, Januarsih; Megawati, Megawati
JURNAL RAKAT SEHAT (JRS) : Pengabdian Kepada Masyarakat Vol 2 No 1 (2023): Jurnal Rakat Sehat: Pengabdian Kepada Masyarakat
Publisher : UPPM Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (414.624 KB) | DOI: 10.31964/jrs.v2i1.29

Abstract

Childbirth is a natural process experienced by women as one of the life cycles, 90-95% of deliveries should be able to proceed normally vaginally without complications. Based on data from the 2017 Indonesian Demographic and Health Survey (IDHS), anxiety or severe pain in labor was 53.9%. When experiencing excessive anxiety, fear, and anxiety, the body will produce stress hormones in the form of adrenaline and increase pain in labor. It was this paradigm that gave birth to a calm and polite birth method that made use of all natural elements, which was called a gentle birth. Gentle birth is one way to prepare pregnant women during pregnancy. Giving birth with a gentle birth gives pregnant women a sense of security and confidence to use their own abilities and strengths to give birth to babies. The activity begins with a physical examination of pregnant women then provides health education about classes for pregnant women and the gentle birth method. The last activity is evaluation and question and answer about health education that has been given to pregnant women. Through this community service activity, it is hoped that it can increase the knowledge of pregnant women in villages that provide services at the Polindes so that pregnant women can face childbirth comfortably and with minimal trauma and pain.
Faktor Faktor Risiko Stress Meningkatkan Kejadian Premenstrual Syndrome (PMS) pada Mahasiswa Kebidanan Poltekkes Kemenkes Banjarmasin Prihatanti, Nur Rohmah; Januarsih, Januarsih; Megawati, Megawati; Sofia, Norlaila
JURNAL KEBIDANAN BESTARI Vol 6 No 1 (2022): Jurnal Kebidanan Bestari
Publisher : Midwifery Departement Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/jkb.v6i1.89

Abstract

Premenstrual Syndrome (PMS) is a collection of moderate to severe affective and physical symptoms that develop during the luteal phase of the menstrual cycle and disappear within a few days of menstruation. Complaints of Premenstrual Syndrome (PMS) that often occur are anxiety, fatigue, difficulty concentrating, difficulty sleeping, loss of energy, headache, abdominal pain, and breast pain. The prevalence of Premenstrual Syndrome (PMS) reaches 90% of the entire population of women of childbearing age in the world. In Indonesia, it reaches 85% experienced by women of childbearing age. As many as 20-50% of them experience severe Premenstrual Syndrome (PMS) symptoms that interfere with daily activities. The incidence of Premenstrual Syndrome (PMS) can increase because it is influenced by several risk factors, one of which is stress. The study used an analytical observational research design with a cross sectional approach. The research was conducted at the Midwifery Department of the Health Poltekkes of the Ministry of Health Banjarmasin and carried out in August-December 2021 with a population of all third semester students of the three diploma study program majoring in midwifery Poltekkes Ministry of Health Banjarmasin for the 2021/2022 academic year, which is as many as 40 people. Sample selection using simple random sampling method. Samples were taken randomly from the third semester student population of the three diploma study program majoring in midwifery for the 2021/2022 academic year with the requirement that they have experienced menstruation. The sample was calculated using the Slovin formula and the number of samples was 35 people. The independent variable is stress with the research instrument in the form of a questionnaire and the dependent variable is Premenstrual Syndrome (PMS) with the research instrument in the form of a questionnaire The Shortened Premenstrual Assessment Form (SPAF). From the results of a simple linear regression test, the results of the calculation of p-value = 0.000 or the value of Sig. 0.000 < 0.05, which means that stress increases the incidence of Premenstrual Syndrome (PMS) in students of the Department of Midwifery, Poltekkes Kemenkes Banjarmasin. Keyword: Students, Premenstrual Syndrome (PMS), Stress