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Antibacterial Activity from Fraction of Liquid-Liquid Extraction in Temulawak Rhizome (Curcuma xanthorrhiza Roxb.) Alighiri, Dante; Firnanda, Indah Putri; Abdullah, Ravely Adhitya; Widodo, Naufaldi Bani; Drastisianti, Apriliana
Walisongo Journal of Chemistry Vol. 7 No. 2 (2024): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v7i2.23333

The rhizome of Temulawak (Curcuma xanthorrhiza Roxb) has been traditionally used to treat various ailments due to its rich content of curcumin, demethoxycurcumin, and bisdemethoxycurcumin. These compounds exhibit notable antioxidant and antibacterial properties. This study aimed to evaluate the antibacterial efficacy of Temulawak rhizome extracts in n-hexane, ethyl acetate, and methanol, focusing on Escherichia coli and Staphylococcus aureus. The extraction process involved successive maceration with each solvent. The antibacterial activity was tested using well diffusion and microdilution methods, determining minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Phytochemical screening revealed the presence of flavonoids, alkaloids, phenolics, steroids, and triterpenoids in the extracts. The results indicated that the n-hexane and ethyl acetate fractions exhibited intense antibacterial activity against Staphylococcus aureus, while all fractions showed potent activity against Escherichia coli. The MIC values ranged from 39.0625 to 625 ppm for Staphylococcus aureus and 39.0625 to 78.125 ppm for Escherichia coli, with MBC values generally higher than MIC values. These findings highlight the potential of Temulawak rhizome extracts as effective antibacterial agents.

Antibacterial Activity from Fraction of Liquid-Liquid Extraction in Temulawak Rhizome (Curcuma xanthorrhiza Roxb.) Alighiri, Dante; Firnanda, Indah Putri; Abdullah, Ravely Adhitya; Widodo, Naufaldi Bani; Drastisianti, Apriliana
Walisongo Journal of Chemistry Vol. 7 No. 2 (2024): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology UIN Walisongo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/wjc.v7i2.23333

The rhizome of Temulawak (Curcuma xanthorrhiza Roxb) has been traditionally used to treat various ailments due to its rich content of curcumin, demethoxycurcumin, and bisdemethoxycurcumin. These compounds exhibit notable antioxidant and antibacterial properties. This study aimed to evaluate the antibacterial efficacy of Temulawak rhizome extracts in n-hexane, ethyl acetate, and methanol, focusing on Escherichia coli and Staphylococcus aureus. The extraction process involved successive maceration with each solvent. The antibacterial activity was tested using well diffusion and microdilution methods, determining minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Phytochemical screening revealed the presence of flavonoids, alkaloids, phenolics, steroids, and triterpenoids in the extracts. The results indicated that the n-hexane and ethyl acetate fractions exhibited intense antibacterial activity against Staphylococcus aureus, while all fractions showed potent activity against Escherichia coli. The MIC values ranged from 39.0625 to 625 ppm for Staphylococcus aureus and 39.0625 to 78.125 ppm for Escherichia coli, with MBC values generally higher than MIC values. These findings highlight the potential of Temulawak rhizome extracts as effective antibacterial agents.

Risk analysis of air quality for parameters NO2, SO2, NH3, and Ox from the area around fertilizer industries in Indonesia Alighiri, Dante; Widodo, Naufaldi Bani; Abdullah, Ravely Adhitya; Firnanda, Indah Putri; Drastisianti, Apriliana
Journal of Natural Sciences and Mathematics Research Vol. 11 No. 1 (2025): June
Publisher : Faculty of Science and Technology, Universitas Islam Negeri Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/jnsmr.v11i1.23331

Industrial zones with intensive human activities often experience air-quality degradation, particularly in areas surrounding fertilizer production facilities. This study analyzes the concentrations of nitrogen dioxide (NO₂), sulfur dioxide (SO₂), ammonia (NH₃), and oxidants (Ox) in the ambient air around fertilizer industries in Indonesia and evaluates their potential non-carcinogenic health risks. Air sampling was conducted using an InScienPro US-1012 impinger equipped with selective absorbent solutions. Pollutant concentrations were quantified using UV-Vis spectrophotometry based on the Griess–Saltzman method for NO₂, the pararosaniline method for SO₂, the indophenol method for NH₃, and the neutral buffer potassium iodide method for Ox. Concentrations were compared with national ambient air-quality standards. To strengthen the assessment, a quantitative health-risk evaluation was incorporated using the Hazard Quotient (HQ) and Hazard Index (HI), allowing for the interpretation of long-term exposure impacts. Results show that most pollutant concentrations were below regulatory limits; however, SO₂ levels at one sampling point and NH₃ levels near the production zone were elevated. The HQ–HI analysis revealed that SO₂ at the office-area sampling point (HQ = 0.794) and NH₃ inside the processing plant (HQ = 2.238) were the dominant contributors to cumulative exposure, with HI values exceeding 1 at both locations. These findings indicate potential non-carcinogenic risks for individuals chronically exposed in areas closest to emission sources. Overall, this study highlights the importance of continuous monitoring and risk-based evaluation to identify localised hotspots, inform mitigation strategies, and enhance emission control practices in fertiliser-industrial environments.

Correlation between Digital Literacy with Chemical Computational Ability: Chemistry Students at UIN Walisongo Harahap, Lenni Khotimah; Drastisianti, Apriliana
LAVOISIER: Chemistry Education Journal Vol 4, No 2 (2025): LAVOISIER: Chemistry Education Journal
Publisher : UIN Syekh Ali Hasan Ahmad Addary Padangsidimpuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24952/lavoisier.v4i2.17593

This research aims to determine the relationship between digital literacy and chemical computing abilities of Chemistry Education students at UIN Walisongo Semarang. Digital literacy is an important competency that supports 21st century skills, including mastery of technology in chemistry learning. This research uses a quantitative approach with a correlational design. The research population was all 6th semester students taking the Computational Chemistry course, with a total sample of 56 students. The research instruments consisted of a digital literacy questionnaire, computational chemistry practice tests, observation sheets, and interviews. Data analysis was carried out using the Pearson correlation formula. The results showed that there was a positive and significant relationship between digital literacy and students' chemical computing abilities (r = 0.72; p 0.05). This means that students with high digital literacy tend to have better chemical computing skills. This research recommends strengthening digital literacy in the technology-based chemistry learning curriculum.

Correlation between Digital Literacy with Chemical Computational Ability: Chemistry Students at UIN Walisongo Harahap, Lenni Khotimah; Drastisianti, Apriliana
LAVOISIER: Chemistry Education Journal Vol 4, No 2 (2025): LAVOISIER: Chemistry Education Journal
Publisher : UIN Syekh Ali Hasan Ahmad Addary Padangsidimpuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24952/lavoisier.v4i2.17593

This research aims to determine the relationship between digital literacy and chemical computing abilities of Chemistry Education students at UIN Walisongo Semarang. Digital literacy is an important competency that supports 21st century skills, including mastery of technology in chemistry learning. This research uses a quantitative approach with a correlational design. The research population was all 6th semester students taking the Computational Chemistry course, with a total sample of 56 students. The research instruments consisted of a digital literacy questionnaire, computational chemistry practice tests, observation sheets, and interviews. Data analysis was carried out using the Pearson correlation formula. The results showed that there was a positive and significant relationship between digital literacy and students' chemical computing abilities (r = 0.72; p 0.05). This means that students with high digital literacy tend to have better chemical computing skills. This research recommends strengthening digital literacy in the technology-based chemistry learning curriculum.

ANALISIS MODUL AJAR UNTUK MENILAI PEDAGOGICAL CONTENT KNOWLEDGE (PCK) MAHASISWA CALON GURU KIMIA Apriliana Drastisianti; Lenni Khotimah Harahap
STRATEGY : Jurnal Inovasi Strategi dan Model Pembelajaran Vol. 6 No. 3 (2026)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/strategi.v6i3.11246

In the context of ever-evolving education, a strong understanding of pedagogical content knowledge (PCK) is crucial for prospective chemistry teachers to teach effectively and innovatively. This study aims to determine the PCK of prospective chemistry teachers. The research method used is descriptive qualitative. The subjects of this study were 49 students of the Chemistry Education Study Program in the 2024/2025 academic year who were taking the Microlearning course. Data were collected through documentation analysis using qualitative descriptions of open modules created by prospective chemistry teachers for teaching practice. Based on the results of the data analysis, it was found that the content knowledge (CK) of prospective chemistry teachers was very good (81.55%), pedagogical knowledge (PK) was very good (83.19%), and PCK was good (77.20%). The results of this study indicate that although students have a strong understanding of CK and PK, there is room for PCK development. These findings provide opportunities for curriculum development and training for prospective chemistry teachers and encourage further research on the factors influencing PCK mastery. This study is expected to serve as a reference for educators and curriculum developers in improving the quality of education for prospective chemistry teachers. ABSTRAK Dalam konteks pendidikan yang terus berkembang, pemahaman yang kuat mengenai pedagogical content knowledge (PCK) menjadi krusial bagi calon guru kimia untuk dapat mengajar dengan efektif dan inovatif. Penelitian ini bertujuan untuk mengetahui PCK calon guru kimia. Metode penelitian yang digunakan yaitu deskriptif kualitatif. Subjek penelitian ini adalah 49 mahasiswa Program Studi Pendidikan Kimia tahun ajaran 2024/2025 yang menempuh mata kuliah Pembelajaran Mikro. Data dikumpulkan dengan dokumentasi menggunakan analisis secara deskriptif kualitatif terhadap modul ajar yang dibuat oleh mahasiswa calon guru untuk praktik mengajar. Berdasarkan hasil analisis data ditemukan bahwa kemampuan content knowledge (CK) mahasiswa calon guru kimia termasuk baik sekali (81,55%), pedagogical knowledge (PK) termasuk baik sekali (83,19%), dan PCK termasuk baik (77,20%). Hasil penelitian ini menunjukkan bahwa meskipun mahasiswa memiliki pemahaman yang kuat dalam CK dan PK, terdapat ruang untuk pengembangan PCK. Temuan ini memberikan kesempatan bagi pengembangan kurikulum dan pelatihan calon guru kimia, serta mendorong penelitian lebih lanjut mengenai faktor-faktor yang mempengaruhi penguasaan PCK. Penelitian ini diharapkan dapat menjadi referensi bagi pendidik dan pengembang kurikulum dalam meningkatkan kualitas pendidikan calon guru kimia.

Effectiveness of Guided Inquiry Learning With PhET Simulation to Improve Students’ Critical Thinking Ability and Understanding of Reaction Rate Concepts Drastisianti, Apriliana; Dewi, Arini Kusuma; Alighiri, Dante
International Journal of Pedagogy and Teacher Education Vol 8, No 2 (2024): International Journal of Pedagogy and Teacher Education - October
Publisher : The Faculty of Teacher Training and Education (FKIP), Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/ijpte.v8i2.93924

In modern education, fostering critical thinking skills is essential, enabling students to analyze, interpret, and conclude information effectively. This study evaluates the effectiveness of a guided inquiry learning model integrated with PhET simulations in enhancing students' critical thinking abilities and comprehension of reaction rate concepts. The research was quasi-experimental and assigned to experimental and control groups. The study employed pretest and posttest measures using essay questions to assess critical thinking and conceptual understanding. Results from the t-tests demonstrated significant improvements in both critical thinking (count = 2.240 > table = 1.666) and conceptual understanding (count = 3.064 > table = 1.666) for students engaged in guided inquiry with PhET simulations compared to those in traditional discovery learning settings. These findings underscore the potential of guided inquiry supported by simulations to create an interactive and engaging learning environment, promoting deeper cognitive processing and retention. By merging inquiry-based learning with technological tools, educators can enhance student engagement and facilitate a hands-on approach to complex topics, preparing students for more sophisticated academic and real-world problem-solving scenarios. This study suggests that guided inquiry, complemented by PhET simulations, strengthens conceptual foundations and nurtures critical analytical skills necessary for academic success and beyond

Development of Chemical Crossword Puzzle (Tekilama) Periodic System of Elements as a Companion Learning Media Khumar, Krisna; Drastisianti, Apriliana
Social, Humanities, and Educational Studies (SHES): Conference Series Vol 6, No 4 (2023): Social, Humanities, and Educational Studies (SHEs): Conference Series
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/shes.v6i4.81229

Penelitian pengembangan ini dilatar belakangi pada penggunaan media kimia yang digunakan belum maksimal sehingga peserta didik kurang terlibat aktif dalam pembelajaran. Tujuan penelitian ini yaitu untuk mengembangkan media pembelajaran pendamping materi sistem periodik unsur dan menguji kualitas media pembelajaran yang dikembangkan. Penelitian pengembangan ini menggunakan model penelitian ADDIE. Karakteristik dari media pembelajaran ini yaitu memuat materi sistem periodik unsur dan latihan soal yang dikemas dalam bentuk teka teki silang. Hasil validasi ahli materi mendapatkan kriteria valid dengan nilai 4, sedangkan hasil validasi ahli media mendapatkan kriteria valid dengan nilai 4,08. Hasil dari penilaian peserta didik menapatkan kriteria sangat valid dengan nilai 4,27. Dengan demikian dapat disimpulkan bahwa media pembelajaran tekilama layak digunakan.

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