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All Journal International Journal of Social Science and Business Jurnal Pembelajaran dan Biologi Nukleus Indonesian Journal of Pharmaceutical and Clinical Research IJOEP : International Journal of Ecophysiology Jurnal Farmanesia Herbal Medicine Journal Jurnal ABDIMAS MUTIARA
Prayoga, Andre
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Sosialisasi Dan Pelaksanaan Pencegahan Osteoporosis Pada Lansia Di Puskesmas Selayang Medan Prayoga, Andre; Harmoni Tarigan, Modesta; Paulus Ginting, Ferdinand; Lifiani, Rialita
Jurnal Abdimas Mutiara Vol. 6 No. 1 (2025): JURNAL ABDIMAS MUTIARA
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Obat-obatan umumnya digunakan untuk meningkatkan kesehatan dan mencegah penyakit. Penyakit yang disebut osteoporosis melibatkan penurunan kepadatan tulang dan perubahan mikroarsitektur tulang. Tulang menjadi rapuh dan lebih mudah patah. Tujuan dari program informasi ini adalah untuk meningkatkan kesadaran tentang penggunaan dan penanganan obat yang benar di kalangan masyarakat umum, khususnya para lansia. Dalam rangka Hari Lanjut Usia Nasional, topik mengenai pengenalan pencegahan osteoporosis menjadi sorotan mengingat osteoporosis merupakan "pembunuh diam-diam" yang jarang sekali diketahui, khususnya di kalangan lanjut usia. Mahasiswa dan dosen Program Studi Pendidikan Vokasi Apoteker dan Program Sarjana Farmasi Universitas Sari Mutiara Indonesia diminta untuk meningkatkan pengetahuan tentang pencegahan osteoporosis pada lansia di Puskesmas Medan Selayang. Ini adalah salah satu dari Tiga Cara Aktivisme di Perguruan Tinggi: Mendedikasikan diri Anda pada komunitas Anda. Sosialisasi ini diharapkan dapat memberikan pengetahuan dan pemahaman yang secara tidak langsung dapat mencegah penggunaan obat yang salah dan mencegah terjadinya osteoporosis.
HEART HEALTH AWARENESS: MENUMBUHKAN KESADARAN MASYARAKAT TENTANG KESEHATAN JANTUNG DI KLINIK PRATAMA NUSANTARA KESEHATAN Prayoga, Andre; Fitri, Raissa; br Ginting, Grace Anastasia; Waruwu, Syukur Berkat; Utama, Rezza Fikrih; Maimunah, Siti
Jurnal Abdimas Mutiara Vol. 6 No. 2 (2025): JURNAL ABDIMAS MUTIARA (IN PRESS)
Publisher : Universitas Sari Mutiara Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jam.v6i2.6134

Abstract

Latar belakang: Penyakit jantung masih menjadi penyebab utama kematian di Indonesia dan dunia. Kurangnya pemahaman masyarakat terhadap faktor risiko serta pencegahan penyakit jantung menjadi latar penting untuk dilakukan edukasi kesehatan..Tujuan: Kegiatan pengabdian ini bertujuan untuk meningkatkan kesadaran masyarakat tentang pentingnya menjaga kesehatan jantung. Metode: Kegiatan dilaksanakan pada tanggal 23 Mei 2025 di Klinik Pratama Nusantara Kesehatan, Jalan Bakti Luhur No. 17 Medan. Sasaran kegiatan adalah masyarakat sekitar lokasi kegiatan. Kegiatan terdiri dari edukasi kesehatan jantung, pemeriksaan tekanan darah, pengukuran denyut nadi, serta sesi konsultasi oleh dosen dan mahasiswa Program Studi Profesi Apoteker Universitas Sari Mutiara Indonesia. Hasil: Kegiatan ini diikuti oleh ±50 orang peserta dengan antusiasme tinggi. Lebih dari 30% peserta memiliki tekanan darah tinggi namun belum pernah mendapatkan edukasi atau pemeriksaan sebelumnya. Setelah dilakukan edukasi, terjadi peningkatan pemahaman peserta terhadap faktor risiko dan pencegahan penyakit jantung berdasarkan hasil evaluasi singkat. Kesimpulan: Kegiatan edukasi kesehatan jantung ini memberikan dampak positif terhadap peningkatan kesadaran masyarakat, dan dapat dijadikan model untuk kegiatan promotif-preventif berkelanjutan di komunitas.
Formulasi Ekstrak Etanol Kulit Kopi (Coffea arabica L.) dalam Sediaan Sabun Padat sebagai Pelembab Alami Dari, Salmiah Wulan; Maimunah, Siti; Prayoga, Andre
Herbal Medicine Journal Vol 8 No 2 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i2.171

Abstract

Coffee skin is rich in antioxidants, vitamins, and minerals that are beneficial for skin health and softness. This study aims to determine the ethanol extract of coffee skin (Coffea arabica L.) formulated in solid soap preparations and effective concentrations of ethanol extract of coffee skin (Coffea arabica L.) concentrations of 2.5% (F1), 5% (F2), and 7.5% (F3) as a natural skin moisturizer in solid soap preparations. This study used an experimental method. Wet sorting, drying, characteristics of simplicia, phytochemical screening, maceration with 70% ethanol, making coffee skin extract with a concentration formulation of 2.5%, 5%, and 7.5% as a blank is a solid soap preparation without the addition of coffee skin extract, examination of the coffee skin extract solid soap preparation, namely organoleptic test, soap pH measurement, homogeneity test, irritation test, and finally humidity test. The four solid soap formulas are homogeneous. pH 9.2-10.5. The results of increasing the humidity of solid soap preparations from 25 volunteers for 28 days from ethanol extract of coffee skin (C. arabica L.) with each concentration were F1 (24.87%), F2 (35.40%), F3 (61.61%), and blank (23.84%). Most preferred in F1. The results of the Post-Hoc Test Turkey HSD analysis after observation from week I to week IV showed a p value> 0.05 meaning there was no significant difference in each formulation in the humidity test. Coffee skin extract (C. arabica L.) can be formulated into solid soap preparations.
PEMANFAATAN EKSTRAK BUAH SALAK (Salacca zalacca (Gaertn.) Voss) SEBAGAI ANTI-AGING ALAMI DALAM SEDIAAN BODY SCRUB Dara, Riza Permata; Maimunah, Siti; Prayoga, Andre
Herbal Medicine Journal Vol 7 No 1 (2024): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v7i1.97

Abstract

This study was aimed at formulating Salak fruit extract in a cream formulation and testing its anti-aging effectiveness. Flavonoid compounds in salak fruit are efficacious as antioxidants that are able to neutralize free radicals so they can improve signs of aging on the skin such as dry skin and enlarged pores and wrinkles. This research was conducted at the Pharmaceutical Chemistry Laboratory of Sari Mutiara Indonesia University in June-August 2023. The tools used were skin analyzer and moisture checker. Salak fruit samples were obtained from the Sihopur village Tapanuli Selatan regency, North Sumatra. The irritation test of three volunteers used salak extract cream with the highest concentration of 7%. The anti-aging activity test used 15 volunteers. Parameters measured include moisture content, number of pores and wrinkles. Statistical data was analyzed using the SPSS method. The results show that the ethanol extract of Salak fruit leaves can be formulated in a homogeneous type A / M cream dosage form, with a pH of 6,3-5,2, a viscosity of 19.000-47.000 cps, non-irritating and stable in storage for 12 weeks. The results of the analysis with the skin analyzer showed that the skin condition changed for the better, namely increased water content 32,3%, reduced pores 10,4% and wrinkles 13,2%. Cream preparations with a concentration of 7% show the best anti-aging effectiveness.
Antibacterial Activity of Patch Silver Nanoparticles and Chitosan with Cellulose Nanofibers Carriers against Staphylococcus aureus and Escherichia coli Prayoga, Andre; Hasibuan, Poppy Anjelisa Zaitun; Yuandani
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 4 No. 2 (2021): Indonesian Journal of Pharmaceutical and Clinical Research (IDJPCR) Vol. 04, No
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v4i2.6169

Abstract

One of the medical needs whose demand continues to increase is wound dressings. The wound cover must also be non-toxic, non-allergenic, made of widely available biomaterials, and have antibacterial properties that can prevent infection of the wound. Chitosan is known to have wound healing activity by acting as a blood-clotting agent and stimulating the formation of new tissue, and silver nanoparticles have good antibacterial activity. Silver Nanoparticles and Chitosan with Cellulose Nanofibers carriers (SNCCN) are made in the form of patches with the ratio formula between cellulose nanofibers and chitosan/silver nanoparticles is 1:9, 2:8, 3:8, 4:7, 5:5, 6:4, 7:3, 8:2, 9:1, and 10:0. Then the antibacterial activity was tested against Staphylococcus aureus and Escherichia coli to find the best formula for antibacterial activity. The analysis showed that the SNCCN patch with a ratio of 9:1 had the best antibacterial activity against Staphylococcus aureus (13.8±0.05 mm) and Escherichia coli (12.5±0.05 mm). It can be concluded that patch Silver Nanoparticles and Chitosan with Cellulose Nanofibers carriers (SNCCN) have good antibacterial activity at a concentration of 9:1 in the category of strong inhibition (10-20 mm).
Hematological and Biochemical Alterations of Andaliman (Zanthoxylum Acanthopodium Dc) with Doxorubicin Induced in White Wistar Rat Prayoga, Andre; Dalimunthe, Aminah; Zumaira; Salim, Emil
International Journal of Ecophysiology Vol. 7 No. 1 (2025): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v7i1.20188

Abstract

Doxorubicin, a well-known chemotherapy drug, is associated with cardiac toxicity primarily due to oxidative stress. This oxidative stress leads to the production of reactive oxygen species and a subsequent decline in antioxidant levels. As doxorubicin induces the formation of free radicals and decreases endogenous antioxidants, it triggers various hematological and biochemical abnormalities. Consequently, the use of antioxidants has been proposed as a strategy to mitigate this damage. This study focuses on the administration of ethanol extract from Andaliman (EAF) fruit, recognized for its rich array of metabolites and antioxidant properties, which may serve as a cardioprotective agent against the adverse effects of doxorubicin. The research involved comprehensive observations, including hematological and clinical chemistry examinations. The findings indicate that EAF demonstrates protective effects by enhancing hematological and clinical chemistry parameters in male Wistar rats subjected to doxorubicin. Notably, these improvements were statistically significant when compared to the control group. Given its promising results, further exploration of EAF as a protective agent for hematological and biochemical health warrants attention and development.
Co-Authors Aminah Dalimunthe br Ginting, Grace Anastasia br Tarigan, Modesta Harmoni Dara, Riza Permata Dari, Salmiah Wulan Dyna Grace Romatua Aruan Emil Salim Fitri, Raissa Ginting, Grace Anastasi Harmoni Tarigan, Modesta Hasibuan, Poppy Anjelisa Zaitun Lestari, Mutiara Dwi Lifiani, Rialita Manurung, Kesaktian Marbun, Eva Diansari Marpaung, Jon Kennedy Paulus Ginting, Ferdinand Purba, Hana Ike Dameria Br. Purba, Roberto Roy Sianipar, Artha Yuliana Siti Maimunah Susanti, Julia Suseno, Eko Tampubolon, Manuppak Irianto Utama, Rezza Fikrih Waruwu, Syukur Berkat Yuandani Zumaira