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All Journal Jurnal Ilmiah Farmasi Indonesian Journal of Pharmaceutical Science and Technology MPI (Media Pharmaceutica Indonesiana) Pharmascience Jurnal Ilmiah Farmasi Farmasyifa Borneo Journal Of Pharmascientech SPIN: Jurnal Kimia & Pendidikan Kimia Lombok Journal of Science Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal Borneo Literasi: Jurnal Pengabdian Masyarakat dan Inovasi Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Jurnal Farmasi SYIFA Jurnal Farmasi dan Farmakoinformatika Borneo Journal of Pharmacy Jurnal Abdimas Multidisiplin Jurnal Pharma Bhakta Jurnal Sains dan Kesehatan
Astuti, Karunita Ika
Fakultas Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Borneo Journal of Pharmacy

 1 
Antidiarrheal Activity of Ethanolic Extract of Vernonia amygdalina Del Leaves againts Male Mice Induced by Oleum Ricini Karunita Ika Astuti; Lusiana Dwi Wulandari; Eka Fitri Susiani
Borneo Journal of Pharmacy Vol. 2 No. 1 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i1.707

Abstract

Leaves of Vernonia amygdalina Del. is one of the alternative plants that people use as antidiarrheal in Martapura, Banjar. The purpose of research to determine the antidiarrheal activity and the effectiveness of ethanolic extract of leaves against male mice. The negative control was given NaCMC 0.5% orally, positive control was given Loperamide HCl 0.005 mg/20 g orally, and groups of ethanolic extract of leaves were given dosages in 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW orally. After 1 hour of treatment, the groups were induced by Oleum ricini orally and were observed for 4 hours. Based on three parameters were frequency, weight, and consistency of diarrhea. From the results observation of that negative control, positive control, EEDA 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW for diarrhea frequency parameter was 7.4 ± 2.30; 2 ± 1.22; 5.8 ± 3.34; 6.2 ± 4.08; 2.4 ± 1.67; the weight parameter was 1.34 ± 0.43; 0.38 ± 0.29;0.66 ± 0.56; 0.57 ± 0.38; 0.49 ± 0.33 and then consistency of diarrhea with EEDA 400 mg/kg BW improved the consistency at 180 minutes compared to control group at 210 minutes. In conclusion, from all parameters of ethanolic extract of Vernonia amygdalina Del. leaves can give an antidiarrhea effect with optimum dosage is 400 mg/kg BW.
Antibacterial Activity Test of Ethanol Extract Pineapple (Ananas comosus (L.) Merr.) Peel against Growth of Propionibacterium acnes Fitriyanti Fitriyanti; Muhammad Nur Rahman Hendrawan; Karunita Ika Astuti
Borneo Journal of Pharmacy Vol. 2 No. 2 (2019): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v2i2.928

Abstract

Pineapple peel (Ananas comosus (L.) Merr.) is waste from the pineapple fruit. The purpose of this study was to determine the content of pineapple peel extract and to antibacterial activity in various concentrations effective in inhibiting the growth of Propionibacterium acnes. The pineapple peel extract is made by using the extraction method in the form of maceration. The method used in the inhibitory test using the three replication samples in each treatment group. The sample consisted of 10 treatment groups ie pineapple peel extract concentration 12.5%, 25%, 37.5%, 50%, 62.5%, 75%, 87.5%, and 100%, as well as positive and negative control. The results obtained from pineapple peel screening contain flavonoid and saponin compounds. The data analysis shows that pineapple peel extract concentrations of 50%, 62.5%, 75%, 87.5%, and 100% had inhibitory zones with the medium-strong category while clindamycin as the control has a strong inhibition zone. The conclusion of this research proves that pineapple peel extract has antibacterial power to P. acnes with effective concentration is 100% with the strong category.
Co-Authors Agung Biworo Akbar, Depy Oktapian Akhmad Junaidi Alista, Siti Aprilia Rahmadina Ari Surya Pratama Aristha N. Putri Baiq Nurdiana Ulfa Bella Rosalina Endah Dharmayati, Evy Eka Fitri Susiani fitriyanti fitriyanti Fitriyanti, Fitriyanti Guntur Kurniawan Hadirvika Tjuthiyanda Helmina Wati Hendrya Legenda Herliana Dewi Hidayati, Listya Nor Hidayatullah, Muhammad Ika P. Sari Khoerul Anwar Lusiana Dwi Wulandari Mariani Monalissa Indriani Muhammad Nazhir Muhammad Nur Rahman Hendrawan Norhasanah Norhasanah Noviadi, Aditya Nur Huda Nurul Hikmah Pangestika, Indira Adi Rahmatullah, Satrio Wibowo Rahmi Muthia Rizaldi, Gusti Rusida, Esty Restiana Sandi, Dita Ayulia Dwi Saputri, Revita Sari Wahyunita Sartika Dewi Sunarti, Lisa Syahrizal Ramadhani Syaid Nofal Assegaf Teuku N.S. Sulaiman Uswatun Rahimah Vebruati Vebruati Wahyudin Wahyudin