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Pengaruh Pemakaian Masker Bedah dan Masker Kain pada Wajah Sutanto, Hans; Saroso, Ade; Setyaningrum, Dyah; Ilona, Florinda
Sanus Medical Journal Vol. 4 No. 2 (2022)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v4i2.10040

Background. Face masks are indispensable in preventing the spread of COVID-19 transmission. Face mask use can have beneficial and detrimental effects on a person. In this study, participants' faces were observed before and after wearing surgical and cloth masks for 4 hours per day for five consecutive days. Methods. The research design is experimental. Results. Thirty-two Trisakti University Faculty of Medicine employees aged 26 to 46 years and 18 men and 14 women, participated in this study. Sociodemographic data and facial examination were assessed at the start and end of the study. The research data obtained the results of p = 0.392. Conclusion. There is no significant difference between surgical and cloth masks in terms of acne, skin irritation, and redness.

Pencegahan Kanker Payudara Melalui Penyuluhan di Masyarakat Nagrak Digambiro, Reza Aditya; Chendrasari, Julian; Ilona, Florinda; Lestari, Indah Widya; Setyaningrum, Dyah Ayu Woro; Fadillah, Ibnu Haris
Jurnal Pengabdian Masyarakat Bangsa Vol. 2 No. 11 (2025): Januari
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v2i11.1922

Kanker payudara tetap menjadi masalah kesehatan masyarakat yang signifikan di Indonesia, terutama di daerah berkembang seperti Nagrak. Tantangan dalam deteksi dini akibat kurangnya kesadaran, fasilitas kesehatan yang terbatas, dan stigma budaya memperburuk prevalensi dan mortalitas akibat kanker payudara. Program pengabdian masyarakat yang dilakukan oleh Fakultas Kedokteran Universitas Trisakti bertujuan untuk meningkatkan kesadaran masyarakat dan memberdayakan perempuan di Nagrak untuk melakukan pemeriksaan payudara sendiri (SADARI) sebagai langkah pencegahan. Program ini melibatkan survei awal untuk menilai pengetahuan masyarakat, diikuti dengan seminar edukasi dan sesi simulasi SADARI yang dipandu oleh tenaga medis dan mahasiswa. Evaluasi pasca-kegiatan menunjukkan peningkatan signifikan dalam pengetahuan dan keterampilan peserta, yang menegaskan efektivitas program ini. Rekomendasi utama meliputi pelaksanaan edukasi rutin, penguatan kerjasama dengan fasilitas kesehatan lokal, dan pemanfaatan media digital untuk memperluas dampak edukasi. Inisiatif ini menegaskan pentingnya pendekatan berbasis komunitas dalam menurunkan prevalensi kanker payudara melalui deteksi dini dan perubahan gaya hidup.

The Impact of High Dose Ozone Therapy on Hematological and Biochemical Profiles : An Observational Study Digambiro, Reza Aditya; Parwanto, Edy; Lestari, Indah Widya; Chendrasari, Julian; Setyaningrum, Dyah Ayu Woro; Ilona, Florinda
The Avicenna Medical Journal Vol 5, No 1 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i1.34859

Background: Ozone therapy, namely High Dose Ozone Therapy (HDO), has become a versatile medical treatment in several clinical settings. Although it is becoming more well acknowledged, there is still a lack of extensive evidence about the impact of this on hematological and biochemical indicators. This study seeks to address this void by examining the consequences of this phenomenon in a clinical environment.Method: An observational study was done, which followed a structured approach, comprising a total of 100 patients who were selected from the SMC Clinic. Hematological and biochemical indices were evaluated before and after ozone therapy sessions to analyze blood parameters. Two blood samples were obtained at two specific time points: prior to the commencement of the ozone therapy (T0) and after the therapy was finished (T1).Results: Substantial alterations were noted in both hematological and biochemical parameters after the therapy. The hematological changes observed in this study showed a substantial rise in the red blood cell count (p=0.009), hemoglobin levels (p=0.004), and hematocrit (p=0.039), along with a decrease in erythrocyte sedimentation rate (ESR) (p=0.020). Notable biochemical changes were observed, including significant modifications in total plasma protein (TPP) (p=0.008) and lactate levels (p=0.001). Furthermore, there was a noteworthy decrease (p<0.05) in the levels of malondialdehyde (MDA), which is a marker for oxidative stress.Conclusion: HDO exerts a regulatory influence on crucial hematological, biochemical, and oxidative stress factors. These findings indicate that HDO may have therapeutic benefits for treating chronic disorders and cancer. It can improve blood parameters and reduce oxidative stress. The decrease in markers of oxidative stress, such as MDA, suggests a potential reduction in the likelihood of problems associated with oxidative damage in chronic diseases. Nevertheless, additional research is required to validate these findings, investigate their wider therapeutic implications, and comprehend the long-term consequences and safety of HDO therapy.

THE USE OF TELEMEDICINE IN PRIMARY HEALTHCARE SERVICES IN JAKARTA Digambiro, Reza Aditya; Ilona, Florinda; Setyaningrum, Dyah Ayu Woro; Chendrasari, Julian; Lestari, Indah Widya
HEARTY Vol 13 No 3 (2025): JUNI
Publisher : Fakultas Ilmu Kesehatan, Universitas Ibn Khaldun, Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/hearty.v13i3.18339

Background: The advancement of digital technology has transformed the healthcare sector, and telemedicine has become an important innovation in providing remote clinical services. Methods: The research method used is a mixed-method approach, combining quantitative and qualitative approaches. Data collection was conducted through questionnaires distributed to 400 telemedicine users. The sample size was determined using the Slovin formula with a 5% margin of error. Results: 75% of respondents used telemedicine more than once in the past year, with 70% of respondents expressing high satisfaction with the services received. The main reasons for using telemedicine include convenience (65%) and time savings. However, several challenges were identified, such as technical issues (30%), lack of physical examinations, and concerns about service quality. Discussion: The main challenges identified include inadequate technological infrastructure, low digital literacy among certain groups, and unclear regulations. Development opportunities include the integration of telemedicine with electronic health records and increased public education. Conclusion: Telemedicine has great potential to improve the accessibility and efficiency of healthcare services in Jakarta. However, improvements in infrastructure, digital literacy, and supportive regulatory frameworks are needed to maximize the benefits of telemedicine within the healthcare system.

PENYULUHAN KESEHATAN SEBAGAI UPAYA MENINGKATKAN KUALITAS HIDUP LANSIA DI POSYANDU BERINGIN III, BEKASI Digambiro, Reza Aditya; Ilona, Florinda; Chendrasari, Julian; Lestari, Indah Widya; Setianingrum, Dyah Ayu Woro
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 3 No 03 (2025): JUNI 2025
Publisher : Media Inovasi Pendidikan dan Publikasi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Lansia merupakan kelompok masyarakat yang memiliki risiko tinggi terhadap berbagai penyakit degeneratif, terutama akibat perubahan fisiologis seiring bertambahnya usia. Kondisi ini diperparah oleh rendahnya tingkat pendidikan, kurangnya akses terhadap informasi kesehatan, dan minimnya aktivitas fisik di kalangan lansia. Penyuluhan kesehatan berbasis komunitas menjadi salah satu upaya strategis untuk meningkatkan kualitas hidup lansia. Kegiatan ini dilaksanakan di Posyandu Beringin III, Jaticempaka, Bekasi, dengan metode seminar edukatif dan simulasi praktik langsung untuk meningkatkan pemahaman lansia tentang pola hidup sehat, deteksi dini penyakit degeneratif, serta pentingnya menjaga kesehatan mental dan sosial. Kegiatan ini melibatkan 30 peserta lansia dan dipandu oleh tim dari Fakultas Kedokteran Universitas Trisakti. Evaluasi kegiatan menunjukkan adanya peningkatan signifikan dalam pengetahuan dan kesadaran peserta terhadap pentingnya perilaku hidup sehat. Melalui program ini, diharapkan lansia dapat lebih mandiri dalam menjaga kesehatannya dan tetap produktif dalam kehidupan sehari-hari.

Umbilical Cord MSC-Secretome Therapy Enhances Erectile Function in Elderly Men Digambiro, Reza Aditya; Fiji, Wijaya Taufik; Ilona, florinda; Chendrasari, Julian
UMI Medical Journal Vol 10 No 1 (2025): UMI Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v10i1.348

Background: Reduced erectile capacity often appears as part of physiological shifts during aging potentially implicating broader physiological or social realms. These declines originate from intricate underlying conditions: endothelial dysfunction, unstable hormonal patterns, compromised vascular structures, oxidative stress escalations, and inflammatory cascades. Recently, attention has drifted towards secretome derived from umbilical cord mesenchymal stem cells (UCMSC)—an eclectic blend of cytokines, extracellular vesicles, and growth factors—suggesting foundational regenerative qualities surpassing conventional symptomatic therapies, like phosphodiesterase-5 inhibitors (PDE-5i). Methods: In this study, ederly male participants (n=64, aged ≥60) diagnosed with erectile dysfunction (ED) received intracavernosal UCMSC-secretome injections every two weeks for three sessions. No control group was included; efficacy was tracked through pre- and post-intervention evaluations using the International Index of Erectile Function (IIEF-5). Results: A statistically notable improvement emerged—average IIEF-5 scores increasing by about 5.49 points (p<0.001; Cohen’s d=1.99). With the satisfaction averaging approximately 8.03/10. Conclusion: Extensive, randomized controlled trials could more conclusively elucidate the genuine potential of secretome interventions.

Cervical cancer screening before hysterectomy in pelvic organ prolapse patients: Is it essential? A case series Aryasatiani, Ekarini; Surya, Raymond; Harjanti, Dyonesia Ary; Ilona, Florinda; Kartika, Chandra Dewi; Cantika, Catalya Christina; Tenka, Lisda
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.173-179

HIGHLIGHTS More advanced cervical precancerous histopathological findings compared with cervical cytology are observed in POP patients undergoing vaginal hysterectomy. Routine use of preoperative biopsy or ultrasound in POP patients undergoing vaginal hysterectomy cannot be recommended. ABSTRACT Objective: Pelvic organ prolapse (POP) results from weakening of the pelvic floor musculature. The reported prevalence of unexpected premalignant and malignant pathologies following hysterectomy ranges from 0.2 to 0.8%. This study aims to present a case series of patients with POP who underwent vaginal hysterectomy (VH) after preoperative evaluation for abnormal cervical cytology, which subsequently demonstrated more advanced histopathological findings. Case Series: Case 1: A 55-year-old woman, P3A0, was diagnosed with third-degree uterine prolapse and cystocele. Pap smear revealed atypical glandular cells of undetermined significance (AGUS). Histopathological examination after VH demonstrated vaginitis and metaplastic chronic cervicitis with atypia progressing to mild dysplasia of endocervical epithelial cells/low-grade squamous intraepithelial lesion (LSIL). Case 2: A 62-year-old woman, P5A0, was diagnosed with third-degree uterine prolapse. Pap smear revealed atypical squamous cells of undetermined significance (ASCH). Histopathological evaluation after VH demonstrated high-grade squamous intraepithelial lesion (HSIL) up to carcinoma in situ with microinvasive glandular involvement and focal extension. Conclusion: Given that cervical cancer remains the second leading cause of mortality among women in Indonesia, preoperative screening for precancerous gynecological lesions and malignancy is strongly recommended.

The Impact of High Dose Ozone Therapy on Hematological and Biochemical Profiles : An Observational Study Digambiro, Reza Aditya; Parwanto, Edy; Lestari, Indah Widya; Chendrasari, Julian; Setyaningrum, Dyah Ayu Woro; Ilona, Florinda
The Avicenna Medical Journal Vol. 5 No. 1 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i1.34859

Background: Ozone therapy, namely High Dose Ozone Therapy (HDO), has become a versatile medical treatment in several clinical settings. Although it is becoming more well acknowledged, there is still a lack of extensive evidence about the impact of this on hematological and biochemical indicators. This study seeks to address this void by examining the consequences of this phenomenon in a clinical environment.Method: An observational study was done, which followed a structured approach, comprising a total of 100 patients who were selected from the SMC Clinic. Hematological and biochemical indices were evaluated before and after ozone therapy sessions to analyze blood parameters. Two blood samples were obtained at two specific time points: prior to the commencement of the ozone therapy (T0) and after the therapy was finished (T1).Results: Substantial alterations were noted in both hematological and biochemical parameters after the therapy. The hematological changes observed in this study showed a substantial rise in the red blood cell count (p=0.009), hemoglobin levels (p=0.004), and hematocrit (p=0.039), along with a decrease in erythrocyte sedimentation rate (ESR) (p=0.020). Notable biochemical changes were observed, including significant modifications in total plasma protein (TPP) (p=0.008) and lactate levels (p=0.001). Furthermore, there was a noteworthy decrease (p<0.05) in the levels of malondialdehyde (MDA), which is a marker for oxidative stress.Conclusion: HDO exerts a regulatory influence on crucial hematological, biochemical, and oxidative stress factors. These findings indicate that HDO may have therapeutic benefits for treating chronic disorders and cancer. It can improve blood parameters and reduce oxidative stress. The decrease in markers of oxidative stress, such as MDA, suggests a potential reduction in the likelihood of problems associated with oxidative damage in chronic diseases. Nevertheless, additional research is required to validate these findings, investigate their wider therapeutic implications, and comprehend the long-term consequences and safety of HDO therapy.

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