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All Journal Majalah Obstetri dan Ginekologi Hearty : Jurnal Kesehatan Masyarakat Jurnal Biomedika dan Kesehatan UMI Medical Journal Jurnal ABDINUS : Jurnal Pengabdian Nusantara Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran The Avicenna Medical Journal Hang Tuah Medical Journal The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Pengabdian Masyarakat Bangsa GEMBIRA (Pengabdian Kepada Masyarakat) Jurnal Kedokteran Meditek Sanus Medical Journal Jurnal Pengabdian Masyarakat Mandira Cendikia (JPKM-MC) Cermin Dunia Kedokteran
Ilona, Florinda
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D-dimer sebagai Biomarker Diagnostik Tuberkulosis Paru pada Efusi Pleura: Tinjauan Pustaka Digambiro, Reza Aditya; Ilona, Florinda; Chendrasari, Julian; Lestari, Indah Widya; Parwanto, Edy
Cermin Dunia Kedokteran Vol 52 No 2 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i2.1242

Abstract

Background: Tuberculosis (TB) remains a major health threat, especially in developing countries. Although the lungs are the most affected organ, systemic manifestations are quite significant. D-dimer, as one of the fibrin degradation products and also an indicator of coagulation activity, has been extensively researched for its predictive and diagnostic value in various diseases. This study aims to assess the effectiveness of D-dimer as a diagnostic biomarker for pulmonary tuberculosis (TB) in patients with pleural effusion compared to those with non-TB pleural effusion. Methods: The study was conducted as an observational case-control on 64 patients with pulmonary TB with pleural effusion were compared to 64 non-TB subjects with pleural effusion. Result: In the TB patient group, 62.5% of patients were smokers, 46.9% of patients had been exposed to TB. Patients were assessed based on the TB symptom scale and with radiological lung examinations, either x-rays or CT scans. D-dimer levels were correlated with the TB severity. D-dimer levels above the threshold value were significantly higher in patients with severe TB symptoms. Conclusion: A direct correlation was observed between the size of radiological lung lesions and D-dimer levels. The average D-dimer level in the control group was 220 ± 60 ng/mL, which increased to 450 ± 90 ng/mL in TB patients with severe lesions.
Edukasi Pencegahan Kanker Serviks Bagi Ibu PKK Jakarta Utara: Menyambut Bulan Kesadaran Kesehatan Reproduksi Digambiro, Reza Aditya; Parwanto, Edy; Setyaningrum, Dyah Ayu Woro; Chendrasari, Julian; Ilona, Florinda; Lestari, Indah Widya; Hastuty , Dewi
Jurnal Pengabdian Masyarakat Mandira Cendikia Vol. 3 No. 9 (2024)
Publisher : YAYASAN PENDIDIKAN MANDIRA CENDIKIA

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Abstract

Kanker serviks merupakan masalah kesehatan yang signifikan di Indonesia dengan prevalensi tinggi. Edukasi pencegahan kanker serviks melalui deteksi dini dan vaksinasi HPV penting untuk menurunkan angka kejadian dan kematian akibat kanker ini. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan dan kesadaran Ibu-Ibu PKK di Jakarta Utara mengenai pencegahan kanker serviks. Mitra pengabdian adalah Pemerintah Kotamadya Jakarta Utara dan Klinik SMC. Metode yang digunakan adalah presentasi interaktif dan simulasi, diikuti dengan diskusi dan evaluasi pre-test serta post-test untuk mengukur perubahan pengetahuan dan sikap. Hasil menunjukkan peningkatan signifikan pada pemahaman peserta, di mana 70% peserta siap melakukan Pap smear dan 55% siap untuk vaksinasi HPV. Hambatan yang ditemukan adalah waktu pelaksanaan yang terbatas dan masih adanya resistensi terhadap vaksinasi. Edukasi berkelanjutan dan peningkatan akses layanan kesehatan disarankan untuk meningkatkan keberhasilan program di masa mendatang
Hubungan antara Tingkat Pengetahuan tentang Kanker Serviks dan Hasil Pap Smear pada Wanita Dewasa DIGAMBIRO, REZA ADITYA; ILONA, FLORINDA; CHENDRASARI, JULIAN; SETYANINGRUM, DYAH AYU WORO; LESTARI, INDAH WIDYA
Hang Tuah Medical Journal Vol 23 No 1 (2025): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v23i1.809

Abstract

Cervical cancer can arise from a persistent infection with Human Papillomavirus (HPV), which can be avoided through early detection by pap smear screening. Having adequate knowledge about cervical cancer is crucial for encouraging participation in pap smear tests, which can detect non-cancerous or precancerous changes before they progress. This cross-sectional descriptive-analytic study aimed to assess knowledge levels about cervical cancer and their correlation with pap smear results among women of reproductive age in Jakarta, Bogor, and Bekasi (23–50 years). A total of 133 participants underwent a structured questionnaire for assessing knowledge and a pap smear test for evaluating cervical health. The pap smear results showed that 80% were normal, 6% had atypical cells without malignancy, and 14% showed inflammatory lesions. A Chi-square test revealed a significant association between knowledge levels and pap smear outcomes. These findings provide valuable insights for healthcare stakeholders to develop effective health promotion strategies that increase pap smear coverage and encourage early detection of cervical cancer.
Penyuluhan dan Pelayanan Kesehatan Sebagai Upaya Memperbaiki Manajemen Hipertensi Pada Lansia Di Kelurahan Jembatan Lima Kecamatan Tambora Jakarta Sisca, Sisca; Hartanti, Monica Dwi; Setyaningrum, Dyah Ayu Woro; Lestari, Indah Widya; Ilona, Florinda; Chendrasari, Julian; Parwanto, ML Edy
Jurnal ABDINUS : Jurnal Pengabdian Nusantara Vol 4 No 1 (2020): Volume 4 Nomor 1 Tahun 2020
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/ja.v4i1.13977

Abstract

The incidence of hypertension increases with age. Alterations in function and structure in peripheral vascular system are thought to be the cause of high prevalence of hypertension in the elderly. Holistic, patient-centered management of hypertension is needed to prevent deaths from heart failure. This community service aimed to find out the level of knowledge about hypertension in residents of Jembatan Lima Sub-district, Tambora District, West Jakarta. Using a questionnaire, the level of knowledge was studied in 48 participants cross-sectionally. Blood pressure measurements were also carried out to describe the incidence of hypertension in that area. There was a low level of knowledge about hypertension among participants and this had an impact on increasing the risk of hypertension. Fifty-two percent of participants had normal blood pressure, whereas 48% participants were diagnosed as hypertension. Based on demographic data of participants obtained during the event, age, sex, education level and type of work were significantly increasing the risk of hypertension. Results from this community service conclude that the lack of knowledge of hypertension especially in the elderly can increase the risk of hypertension. In order to improve the quality of managing hypertension in the elderly in Jembatan Lima Village, Tambora District, West Jakarta, it is recommended that counseling and discussion groups to be held annually, especially among the elderly.
HIDUP SEHAT TANPA DIABETES : PENYULUHAN BERSAMA WARGA NAGRAK Digambiro, Reza Aditya; Chendrasari, Julian; Krismanuel, Hari; Nugroho, Didi; Ilona, Florinda
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 4 No 01 (2026): FEBRUARI 2026
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Diabetes melitus merupakan masalah kesehatan masyarakat yang terus meningkat, sementara literasi kesehatan dan akses skrining gula darah di wilayah Nagrak masih terbatas sehingga deteksi dini sering terlambat. Kegiatan pengabdian masyarakat ini bertujuan meningkatkan pengetahuan warga tentang faktor risiko, pencegahan, dan deteksi dini diabetes, sekaligus melakukan skrining gula darah sewaktu. Metode yang digunakan adalah penyuluhan luring interaktif dengan media presentasi dan leaflet, dilanjutkan edukasi gaya hidup sehat serta pemeriksaan gula darah sewaktu menggunakan glukometer portabel disertai konseling singkat hasil pemeriksaan. Evaluasi efektivitas dilakukan dengan desain one-group pretest–posttest menggunakan kuesioner pengetahuan. Sebanyak 30 peserta mengikuti kegiatan dan pemeriksaan, didominasi perempuan usia 30–60 tahun. Skor pengetahuan rata-rata meningkat dari 56±12 (pretest) menjadi 78±10 (posttest) atau naik 39% (p<0,001). Distribusi gula darah sewaktu menunjukkan 60,0% normal, 30,0% pradiabetes, dan 10,0% diabetes. Hasil ini menunjukkan penyuluhan berbasis komunitas yang disertai skrining sederhana efektif meningkatkan pengetahuan dan memberikan gambaran awal kebutuhan tindak lanjut di masyarakat. memuat uraian singkat mengenai masalah dan tujuan pengabdian, metode yang digunakan, dan hasil pengabdian.
EFFECT OF INTRAMUSCULAR SECRETOME ON TREATMENT RESPONSE IN TYPE 2 DIABETES MELLITUS PATIENTS DIGAMBIRO, REZA ADITYA; AMARENDRA, GERIE; HASTUTY, DEWI; ILONA, FLORINDA; CHENDRASARI, JULIAN
Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Vol. 9 No. 1 (2026): Al-Iqra Medical Journal: Jurnal Berkala Ilmiah Kedokteran
Publisher : Journal Medical Universitas muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/fgmtjc48

Abstract

Introduction: This study meant to evaluate the efficacy of intramuscular mesenchymal stem cell derived secretome therapy to improve the glycemic control among diabetic patients with Type 2 Diabetes Mellitus (T2DM) on stable insulin or oral hypoglycemic agents (OHO). n=30 per group (Insulin + Secretome; OHO + Secretome). Methods: Pre–post controlled design; biweekly 2 mL intramuscular secretome for 12 weeks; primary outcomes HbA1c, FBG, 2hPP; standard tests per normality. Participants were divided into two groups: Insulin + Secretome and OHO + Secretome. All subjects received intramuscular injections of mesenchymal stem cell (MSC)-derived secretome (2 mL) every two weeks over a 12-week period (six injections total). Primary outcomes included changes in HbA1c, fasting blood glucose (FBG), and two-hour postprandial glucose (2hPPBG). Statistical analyses used paired t-tests or Wilcoxon tests for within-group comparisons and independent t-tests or Mann-Whitney U tests for between-group comparisons. Results: At baseline, both groups had comparable HbA1c and glucose profiles. After 12 weeks, significant reductions were observed in both treatment arms. HbA1c decreased by -1.10 ± 0.45 (Insulin) and -1.33 ± 0.36 (OHO); between-group ΔHbA1c (p < 0.05). Both groups also showed clinically relevant reductions in FBG and 2hPPBG levels. No major adverse effects were reported. Conclusion: Intramuscular MSC-secretome improved glycemic control across background therapies; the benefit was modestly greater with OHO. No majoradverse events were observed
Colonic Leiomyoma Presenting as Sigmoid Volvulus in a Young Male Digambiro, Reza Aditya; Amarendra, Gerie; Ilona, Florinda; Chendrasari, Julian; Kehinde, Samuel Abiodun
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 27, No 1 (2026): VOLUME 27, NUMBER 1, April, 2026
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/271202695-100

Abstract

Colonic leiomyomas are rare tumors that originate from the smooth muscle layer of the colon and are infrequently observed in young individuals. This case report represents a 21-year-old male who presented with a 2-month history of progressive abdominal distension, persistent vomiting, early satiety, and bloating. Computed tomography (CT) of the abdomen suggested sigmoid volvulus with associated bowel obstruction. However, exploratory laparotomy revealed a well-defined, firm intramural mass in the sigmoid colon, leading to segmental resection and primary anastomosis. Histopathological analysis showed intersecting fascicles of bland spindle cells with eosinophilic cytoplasm and cigar-shaped nuclei without atypia or mitotic activity. Immunohistochemistry confirmed positivity for smooth muscle actin (SMA) and negativity for CD117, supporting a diagnosis of colonic leiomyoma and excluding gastrointestinal stromal tumor (GIST). The patient’s postoperative course was uneventful, with complete resolution of obstructive symptoms and restoration of normal bowel function. This case highlights the diagnostic challenge of differentiating colonic leiomyoma from other causes of bowel obstruction, particularly when presenting with features mimicking sigmoid volvulus. It also emphasizes the critical role of histopathology and immunohistochemistry in establishing a definitive diagnosis. Clinicians should consider rare benign tumors in the differential diagnosis of young patients with signs of bowel obstruction.
Co-Authors Aryasatiani, Ekarini Cantika, Catalya Christina Chendrasari, Julian Dewi Hastuty Digambiro, Reza Dyonesia Ary Harjanti Fadillah, Ibnu Haris Fiji, Wijaya Taufik Gerie Amarendra Hari Krismanuel Hastuty , Dewi Kartika, Chandra Dewi Kehinde, Samuel Abiodun Lestari, Indah Widya ML Edy Parwanto Monica Dwi Hartanti, Monica Dwi Nugroho, Didi Parwanto, Edy Raymond Surya Reza Aditya Digambiro Saroso, Ade Setianingrum, Dyah Ayu Woro Setyaningrum, Dyah Ayu Woro Sisca Sisca, Sisca Siti Helmyati Sutanto, Hans Tenka, Lisda