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TESTING THE RESPONSIBILITY OF EGGPLANT THORN (SOLANUM CAROLINENSE) ETHANOL EXTRACT ON THE GROWTH OF BACTERIA (STREPTOCOCCUS MUTANS) IN VITRO Miranti, Indira Pipit; Silviyani, Silviyani
International Journal of Multidisciplinary Research and Literature Vol. 1 No. 3 (2022): INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND LITERATURE
Publisher : Yayasan Education and Social Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (151.003 KB) | DOI: 10.53067/ijomral.v1i3.35

Abstract

Streptococcus mutans is the main pathogenic bacteria causing caries and tooth enamel damage. Eggplant spines (Solanum carolinense) contains active substances that can inhibit the growth of Streptococcus mutans bacteria on teeth. The purpose of this study was to determine the inhibitory effect of the antibacterial activity of ethanol extract of thorn eggplant on the growth of Streptococcus mutans bacteria and to determine the optimal concentration of thorn eggplant extract on the growth of Streptococcus mutans bacteria in vitro. The type of method used in this study is an experimental study, with the dependent variable being the zone of inhibition of the growth of Streptococcus mutans, the independent variable being differences in the concentration of ethanol extract of thorn eggplant (Solanum carolinense) at concentrations of 20%, 40%, 60%, 80% and 96 ethanol. % as negative control and chloramphenicol as positive control, control variables for the presence of other microbial contamination, media thickness, turbidity of bacterial suspension, incubation temperature, disc distance, incubation time, sterilization of equipment, media and room. The results of this study were the effect of the ethanol extract of thorn eggplant on Streptococcus mutans and the optimal concentration of the ethanolic extract of thorn eggplant was 80% with an inhibition zone diameter of 11 mm (strong) which was indicated by the appearance of the diameter of the bacterial inhibition zone at each treatment
ANALISIS KUALITATIF DAN KUANTITATIF KANDUNGAN EUGENOL DALAM JAMU EMPON-EMPON Dewi Iva Rinia; Indira Pipit Miranti; Anisa Annastasya
Jurnal Ilmiah JOPHUS : Journal Of Pharmacy UMUS Vol. 3 No. 02 (2022): Februari
Publisher : Program Studi Farmasi, Universitas Muhadi Setiabudi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46772/jophus.v3i02.648

Abstract

Keanekaragaman tanaman obat yang dimiliki Indonesia sangat banyak, serta penggunaannya dalam masyarakt juga beragama. Salah satu jamu yang sering digunakan sebagai obat yaitu eugenol. Dimana eugenol memiliki fungsi sebagai analgetik, animikroba, dan immunomodulator. Sehingga sangat penting untuk mengetahui kandungan eugenool dalam jamu empon-empon. Penelitian kualitatif dan kuantitaif dilakukan dengan metode KLT-densitometri dengan pelarut toluen: etil asetat: metanol rasio (65: 2,5: 32)v/v. Kurva baku dibuat dengan konsentrasi 10; 15; 20; 25; dan 30 µL/ml. dipeoleh hasil kandungan eugenol dalam sampel tersebut sebanyak 49,28 µl/ml.
JUNIOR HIGH SCHOOL STUDENTS’ CRITICAL THINKING SKILLS BASED ON SELF-RELIANCE LEARNING Gunawan Gunawan; Irfan Saeful Hidayat; Lukmanul Akhsani; Indira Pipit Miranti
Prima: Jurnal Pendidikan Matematika Vol 5, No 1 (2021): Prima: Jurnal Pendidikan Matematika
Publisher : FKIP Universitas Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31000/prima.v5i1.2735

Abstract

The study aims to describe the students ' critical thinking skills reviewed by self-reliance learning. The research methods used are qualitative descriptive. The research subject is a grade VIII A student of SMP Negeri 3 Kalibagor which amounted to 28 people. Sampling is performed using the purposive sampling technique. In one class, selected two students with the category of the self-reliance learned to be seen, three students with the category of the self-reliance began to develop, and two students with a category of self-reliance learning culture. Collection of data using polls, tests, interviews, and documentation. The data analysis techniques used include data reduction, data presentation, and drawing concluding. The validation test used is triangulation. The results showed that more than 80% of the students who had already filled in learning independence poll included categories began to develop. Students of self-reliance category learning culture have a better critical thinking ability compared to the students ' categories begin to look and start developing. However, students with these three learning self-reliance categories do not master the evaluation capability indicator.
Aplikasi Sari Akar Eceng Gondok Pada Media Murashige And Skoog (MS) Sebagai Media Multiplikasi Tanaman Krisan (Chrysanthemum morifolium Ramat, Varietan Puspita Nusantara) Secara In Vitro Indira Pipit Miranti; Vivin Andriani
Quagga : Jurnal Pendidikan dan Biologi Vol 14, No 2 (2022): QUAGGA : Jurnal Pendidikan dan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP Universitas Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25134/quagga.v14i2.4500

Abstract

Chrysanthemum is an ornamental plant commodity that is in great demand by many people, every year the demand for chrysanthemum is increasing so that it requires the availability of good quality seeds in a sustainable manner. The use of in vitro culture techniques is one alternative that can be done. The manufacture of in vitro culture media was modified by the addition of complex organic compounds in accordance with the purpose of propagation. This study aims to determine the concentration of water hyacinth extract which effective in chrysanthemum propagation. The explants used were chrysanthemum nodes. Chrysanthemum multiplication was measured based on two parameters, total of leaves and and the length of the chrysanthemum roots. This research is a randomized complete experimental design with four different concentrations of water hyacinth root extract, concentrations SA (0%, 10%, 20%, 30%). The results showed that water hyacinth root extract had a good effect on the number of leaves and root length. On the parameter of the number of leaves, the addition of 20% water hyacinth root extract to MS medium gave the best results on the parameter of the number of leaves with an average of 13.33, while the root length parameter of MS medium as a control medium without giving water hyacinth root extract gave the highest root length results. with an average of 15.7.
Anti-inflammatory Activity of Taro Stem Ethanol Extract (Colocasia esculenta (L.) Schott) In Vitro Arinda Nur Cahyani; Adi Susanto; Eko Hidayaturrohman Khumaeni; Indira Pipit Miranti; Febia Citraeni; Ratih Widiyanti
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.391 KB)

Abstract

Inflammation is a complex response of vascular tissue to hazards such as pathogens, irritants, and damaged cells/tissues. Inflammation is caused by the release of chemical mediators from damaged tissue and cell migration. The purpose of this study was to determine the efficacy of ethanol extract of taro stem (Colocasia esculenta (L.) Schott) which is used as an anti-inflammatory agent and to determine the concentration of ethanol extract of taro stem (Colocasia esculenta (L.) Schott) which can provide anti-inflammatory activity. The method used in this research is the stability of the red blood cell membrane. The concentrations used were 0 ppm, 25 ppm, 75 ppm, 150 ppm and 100 ppm. The results of the percentage inhibition of hemolysis stability of the red blood cell membrane of taro stem extract concentrations of 0 ppm (00.00%), 25 ppm (82.58%), 75 ppm (83.47%), 150 ppm (47.17%), 100 ppm (24.23%). Testing the anti-inflammatory activity of the ethanol extract of taro stem (Colocasia esculenta (L.) Schott) using the red blood cell membrane stability method has efficacy as an anti-inflammatory agent. The concentration of 25 ppm (82.58%) has the highest anti-inflammatory activity and with a small concentration of extract can produce great anti-inflammatory activity, compared to 100 ppm aspirin as a positive control of 24.23%. Testing the anti-inflammatory activity of the ethanol extract of taro stem (Colocasia esculenta (L.) Schott) using the red blood cell membrane stability method has efficacy as an anti-inflammatory agent. The concentration of 25 ppm (82.58%) has the highest anti-inflammatory activity and with a small concentration of extract can produce great anti-inflammatory activity, compared to 100 ppm aspirin as a positive control of 24.23%. Testing the anti-inflammatory activity of the ethanol extract of taro stem (Colocasia esculenta (L.) Schott) using the red blood cell membrane stability method has efficacy as an anti-inflammatory agent. The concentration of 25 ppm (82.58%) has the highest anti-inflammatory activity and with a small concentration of extract can produce great anti-inflammatory activity, compared to 100 ppm aspirin as a positive control of 24.23%.
Edukasi Parenting dan Pola Makan Anak Sehat Bagi Guru dan Orang Tua TK dan PAUD Desa Jatisaba Cilongok Indira Pipit Miranti; Arinda Nur Cahyani; Rini Dwi Yuliana
jurnal ABDIMAS Indonesia Vol. 1 No. 1 (2023): Maret: Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jai.v1i1.17

Abstract

Desa Jatisaba memiliki geografis berupa pegunungan dan termasuk Desa yang memiliki lahan hutan yang cukup luas. Wilayah yang termasuk ke dataran tinggi ini sebenarnya memiliki potensial yang tinggi sebagai tempat wisata reiligi tetapi pada dasarnya kualitas promosi dari Desa Jatisaba masih kurang gencar sehingga hal tersebut belum terealisasikan. Hal ini membuktikan bahwa sampai pada saat ini belum ada perkembangan terkait dengan pembangunan tempat wisata religi karena kurangnya sosialisasi. Selain itu potensi yang dimiliki Desa Jatisaba yaitu adanya usaha UMKM berupa Home Made keripik pisang kelompok masyarakat. Kelompok masyarakat yang ada di Desa Jatisaba memiliki peranan yang sangat penting dalam membantu berjalannya proses pemanfaatan dan pembuatan baik keripik pisang. Sehingga mampu mengubah atau membentuk wawasan, pengertian, pemikiran minat, tekad dan kemampuan perilaku berinovasi menjadikan sistem usaha yang maju. Pemilihan desa ditentukan karena adanya permintaan dari perwakilan guru-guru TK dan Paud untuk penyuluhan tentang permasalahan yang belum terselesaikan.
THE EFFECT OF APTITUDE TREATMENT INTERACTION LEARNING MODEL ON MATHEMATICAL CREATIVE THINKING SKILLS Yusak Wijaya Y; Gunawan Gunawan; Eka Setyaningsih; Jaka Wijaya Kusuma; Indira Pipit Miranti
International Journal of Multidisciplinary Research and Literature Vol. 2 No. 4 (2023): INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND LITERATURE
Publisher : Yayasan Education and Social Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53067/ijomral.v2i4.142

Abstract

The study aimed to determine the effect of the implementation of the Aptitude Treatment Interaction learning model and its effectiveness on the mathematical thinking skills of SMPN 1 Ajibarang students on the topic of Opportunity, between the ATI (Aptitude Treatment Interaction) experimental class and the control class with the cooperative learning model. This type of research was a quasi-experimental design with two control experiment groups, a pre- test and a post-test design. The results showed differences in student learning outcomes between the two classes, as evidenced by the results of the t-test (2 parties), where the significance value was 0.009 0.025. Thus, there was an average difference between the experimental and the control classes. So, the application of the ATI (Aptitude Treatment Interaction) learning model in the experimental class affects the creative thinking ability of SMP for eighth grader students on the subject of opportunity compared to the control class
Antibacterial Effectiveness Test of Ethanol Extract of Gadung Mango Leaves Against Staphylococcus aureus and Escherichia coli Bacteria Indira Pipit Miranti; Vivin Andriani
Quagga: Jurnal Pendidikan dan Biologi Vol 16 No 1 (2024): QUAGGA : Jurnal Pendidikan dan Biologi
Publisher : Program Studi Pendidikan Biologi, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25134/quagga.v16i1.74

Abstract

Infection is a disease that often occurs in Indonesia. This disease is caused by pathogenic microbes, one of which is bacteria. Staphylococcus aureus and Escherichia coli are bacteria that cause infection. Pharmacological therapy for bacterial infections used to use antibiotics, currently tends to use drugs that come from nature. One of the plants that has the potential as an antibacterial is gadung mango leaves. This study aims to determine the effectiveness of mango leaf ethanol extract against S.aureus and E.coli bacteria. The method used was well diffusion with concentrations of ethanol extract of mango leaves 0.5% (S1), 0.75% (S2), 1% (S3), streptomycin (K+), and ethanol (K-), respectively treatment was repeated 5 times. Data that can be analyzed using One Way ANOVA with a significant level of 0.05. Based on the results of the antibacterial extract of ethanol extract of mango gadung leaves, it has the potential to be better on E. coli bacteria, namely at a concentration of 1% (S3) of 16.05 mm, whereas on S.aureus K+ bacteria (Streptomycin) it is better on control + of 15.9 mm.
Formulasi Krim Antibaktri Ekstrak Etanol Bunga Kecombrang (Etlingera elatior (Jack) R.M.Sm.) Terhadap Propionibacterium acnes Iva Rinia Dewi; Indira Pipit Miranti; Amalia Difa Lestari
Jurnal Penelitian Sains dan Kesehatan Avicenna Vol 2 No 3 (2023): Jurnal Penelitian Sains dan Kesehatan Avicenna
Publisher : Lembaga Penelitian Dan Pengabdian Kepada Masyarakat (LPPM), Institut Teknologi Dan Kesehatan (ITK) Avicenna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69677/avicenna.v2i3.59

Abstract

Latar belakang: Pengobatan jerawat dapat dilakukan dengan menurunkan jumlah koloni Propionibacterium acnes menggunakan antibiotik. Bunga kecombrang mengandung senyawa yang bersifat antibakteri seperti flavonoid, tanin, saponin, terpenoid dan minyak atsiri. Tujuan: PeneIitian ini adalah untuk mengetahui sediaan krim ekstrak etanol bunga kecombrang (Etlingera elatior (Jack) R.M.Sm.) mempunyai aktivitas antibakteri terhadap Propionibacterium acnes. Metode: Jenis penelitian ini yaitu eksperimental menggunakan metode difusi sumuran dengan perbedaan konsentrasi. Konsentrasi ekstrak yang digunakan yaitu F1 = 5%; F2 = 10%; dan F3 = 15% dengan pembanding kontrol negatif = F0 dan kontrol positif = krim klindamisin. EvaIuasi fisik sediaan krim ekstrak etanoI bunga kecombrang terdiri dari uji organoIeptik, uji homogenitas, uji pH, uji daya sebar, uji daya lekat, uji tipe krim, dan uji stabilitas (centrifugal test). Hasil: Hasil dari penelitian ini menunjukkan pada evaluasi fisik sediaan krim ekstrak etanol bunga kecombrang menunjukkan adanya ketidakstabilan krim pada uji centrifugal test dimana terjadi pemisahan fase dan daya sebar krim yang kurang baik. Selanjutnya pada pengujian aktivitas antibakteri sediaan krim ekstrak etanol bunga kecombrang (F1; F2; dan F3) memiliki zona hambat sedang terhadap bakteri Propionibacterium acnes dengan rata-rata zona hambat terbesar yaitu F3 = 9,34 mm. Kesimpulan: sediaan krim ekstrak etanol bunga kecombrang (Etlingera elatior (Jack)R.M.Sm.) mempunyai aktivitas antibakteri terhadap Propionibacterium acnes. Formulasi krim yang paling baik adalah 5%.
Uji Efektifitas Antidiabetes Ekstrak Daun Teh-Tehan (Acalypha Siamensis) Pada Tikus Putih Wistar Jantan Yang Diinduksi Aloksan Ikha Maulana Dewi; Amalia, Ary Nahdiyani; Indira Pipit Miranti
Jurnal Mahasiswa Ilmu Kesehatan Vol. 2 No. 1 (2024): Januari : Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v2i1.938

Abstract

Diabetes Melitus (DM) adalah suatu kelompok penyakit kronis kelainan metabolik yang ditandai dengan meningkatnya kadar glukosa darah melebihi batas normal (hiperglikemia) yang terjadi karena kelainan sekresi insulin, atau resistensi hormon insulin maupun kedua-duanya. Daun teh-tehan (Acalypha siamensis) mengandung flavonoid yang berfungsi sebagai antioksidan dan antidiabetes. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun teh-tehan (Acalypha siamensis) terhadap kadar glukosa darah tikus putih yang diinduksi aloksan. Penelitian ini dilaksanakan di Laboratorium Farmakologi dan Farmakognosi Stikes Ibnu Sina Ajibarang. Metode penelitian ini menggunakan posttes with control design dengan menggunakan subjek penelitian tikus jantan sebanyak 15 ekor yang dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (Aquadest), kelompok kontrol positif (Glibenklamid), dosis 100 mgkgBB, dosis 200 mg/kgBB, dan dosis 300 mg/kgBB. Pengujian efek antihiperglikemik ini menggunakan metode induksi aloksan 120 mg/kg yang dilakukan dengan cara merusak sel beta pankreas pada hewan uji. Parameter yang diamati berupa penurunan kadar glukosa darah pada hari ke-7 dan ke-10. Hasil uji yang diperoleh kemudian di analisis menggunakan software spss secara one-way ANOVA dengan nilai siginifakn p = 0,000 < 0,05 kemudian dilakukan uji lanjut LSD (Least Significant Differens). Kesimpulan dari penelitian ini menunjukan bahwa ekstrak daun teh-tehan berpengaruh terhadap penurunkan kadar glukosa darah pada tikus diabetes akibat induksi aloksan.