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Anemia in Pregnant Women and Its Determinants: A Cross-Sectional Study at Ummu Hani Mother and Children's Hospital, Purbalingga Regency Fitriyani, Novita Endang; Amalia, Ary Nahdiyani; Jayanti, Rosita Dwi; Febriyanti, Rizka; Maryati, Leni
Kesmas Indonesia Vol 16 No 1 (2024): Jurnal Kesmas Indonesia
Publisher : Jurusan Kesehatan Masyarakat dan Fakultas Ilmu-Ilmu Kesehatan Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.ki.2024.16.1.11311

Abstract

Anemia in pregnant women is still a global problem, almost half of all pregnant women throughout the world experience anemia. Ummi Hani Mother and Children Hospital is one of the referral hospitals for mothers and children in Purbalingga that provides the antenatal care service. This research aimed to identify the determinants of anemia in pregnant women at Ummi Hani Mother and Children Hospital, Purbalingga. This research was an analytical observational study with a cross-sectional design. The total sample was 100 pregnant women. Data sources were obtained from medical records, parturition registers, and cohorts of pregnant women at Ummi Hani Mother and Children Hospital. Primary data collection used a structured questionnaire. Bivariate analysis used chi square and/or Fisher exact, and multivariate analysis used logistic regression. This research found that 51% of pregnant women suffered from anemia. The results of multivariate analysis showed that educational level (p value=0.002; OR=5.07; 95% CI=1.79-14.37) and employment status (p value=0.045; OR=2.73; 95% CI=1.02-7.29) were determinants of anemia in pregnant women. This research highlights importance of improving health promotion regarding dangers of anemia and prevention measures such as consuming nutritious and varied foods at affordable prices which is focused on groups of low-educated and unemployed pregnant women.
Uji Efektifitas Antidiabetes Ekstrak Daun Teh-Tehan (Acalypha Siamensis) Pada Tikus Putih Wistar Jantan Yang Diinduksi Aloksan Ikha Maulana Dewi; Amalia, Ary Nahdiyani; Indira Pipit Miranti
Jurnal Mahasiswa Ilmu Kesehatan Vol. 2 No. 1 (2024): Januari : Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v2i1.938

Abstract

Diabetes Melitus (DM) adalah suatu kelompok penyakit kronis kelainan metabolik yang ditandai dengan meningkatnya kadar glukosa darah melebihi batas normal (hiperglikemia) yang terjadi karena kelainan sekresi insulin, atau resistensi hormon insulin maupun kedua-duanya. Daun teh-tehan (Acalypha siamensis) mengandung flavonoid yang berfungsi sebagai antioksidan dan antidiabetes. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun teh-tehan (Acalypha siamensis) terhadap kadar glukosa darah tikus putih yang diinduksi aloksan. Penelitian ini dilaksanakan di Laboratorium Farmakologi dan Farmakognosi Stikes Ibnu Sina Ajibarang. Metode penelitian ini menggunakan posttes with control design dengan menggunakan subjek penelitian tikus jantan sebanyak 15 ekor yang dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (Aquadest), kelompok kontrol positif (Glibenklamid), dosis 100 mgkgBB, dosis 200 mg/kgBB, dan dosis 300 mg/kgBB. Pengujian efek antihiperglikemik ini menggunakan metode induksi aloksan 120 mg/kg yang dilakukan dengan cara merusak sel beta pankreas pada hewan uji. Parameter yang diamati berupa penurunan kadar glukosa darah pada hari ke-7 dan ke-10. Hasil uji yang diperoleh kemudian di analisis menggunakan software spss secara one-way ANOVA dengan nilai siginifakn p = 0,000 < 0,05 kemudian dilakukan uji lanjut LSD (Least Significant Differens). Kesimpulan dari penelitian ini menunjukan bahwa ekstrak daun teh-tehan berpengaruh terhadap penurunkan kadar glukosa darah pada tikus diabetes akibat induksi aloksan.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN MINUM OBAT ANTIHIPERTENSI PADA PASIEN PROLANIS LANSIA DI WILAYAH KERJA PUSKESMAS TAMBAK KABUPATEN BANYUMAS Amalia, Ary Nahdiyani; Fitriyani, Novita Endang; Arfani, Anun
Medical and Health Journal Vol 4 No 1 (2024): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2024.4.1.12172

Abstract

Family is a factor that has a big impact on compliance because it will motivate sufferers to be more confident when dealing with the health problems they are experiencing. This study aims to determine the relationship between support provided by the family and compliance with hypertension treatment in elderly prolanis patients at Tambak 1 and 2 Community Health Centers. The study design used was cross-sectional analytical observation. The research began in April-May 2023 at Tambak 1 and 2 Community Health Centers and was conducted on 92 patients. Data were collected using a questionnaire and Spearman's Rho testing was carried out. The results of the study showed a value of p = 0.002 (p < 0.05), which means that there is a significant relationship between family support and compliance with taking medication for elderly prolanis patients at Tambak 1 and 2 Community Health Centers. The correlation coefficient (r) was obtained at 0.321 and the direction of the relationship obtained a positive r value, meaning that the more the family supports the sufferer, the higher the degree of compliance with treatment. The conclusion that can be drawn is that compliance with hypertension treatment is closely related to the support provided by family members of elderly prolanis patients at Tambak 1 and 2 Community Health Centers. The Community Health Center can provide information, education or health counseling to hypertension prolanis participants about the importance of hypertension treatment compliance and the role of the family. in providing support to maintain stable blood pressure in prolanis patients.
Pemanfaatan Leaflet dan Poster sebagai Media Pendukung Penyuluhan PJK (Penyakit Jantung Koroner) Fadlilah, Synta Haqqul; De Silva, Ghea; Muntafiah, Alfi; Amalia, Ary Nahdiyani; Inayati, Nor Sri; Besari, Arwise Rahman; Untari, Athaya Helia; Aqila, Raghda Aisy
Linggamas: Jurnal Pengabdian Masyarakat Vol 2 No 2 (2025): Linggamas: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.linggamas.2025.2.2.13872

Abstract

Penyakit Jantung Koroner (PJK) merupakan salah satu penyebab utama kematian di dunia, termasuk di Indonesia. Faktor risiko seperti hipertensi, dislipidemia, dan gaya hidup tidak sehat menjadi kontributor utama peningkatan prevalensi PJK. Kegiatan pengabdian ini bertujuan untuk meningkatkan pengetahuan masyarakat mengenai PJK melalui penyuluhan kesehatan yang menggunakan leaflet dan poster sebagai media pendukung. Kegiatan dilakukan di Desa Ledug, Kecamatan Kembaran, Kabupaten Banyumas, dengan melibatkan 34 peserta yang berusia ≥45 tahun dan memiliki riwayat tekanan darah tinggi, kolesterol tinggi, gula darah tinggi, atau obesitas. Metode yang digunakan mencakup pre-test dan post-test untuk mengevaluasi perubahan pengetahuan peserta sebelum dan sesudah edukasi. Penyuluhan dilakukan melalui ceramah oleh dokter spesialis penyakit dalam, didukung distribusi leaflet dan pemasangan poster di lokasi strategis. Hasil menunjukkan peningkatan signifikan rata-rata pengetahuan dari nilai pre-test (59,12) ke post-test (68,82) dengan p=0,000. Hal ini menunjukkan bahwa kombinasi leaflet dan poster sebagai media edukasi efektif dalam meningkatkan pengetahuan peserta mengenai faktor risiko dan pencegahan PJK.
Phytochemical Characterization of the Chloroform Extract of Foeniculum vulgare Mill. Leaves with Implications for Antiparasitic Agent Development Ihtiaringtyas, Suci; Sari, Octavia Permata; Susiawan, Lieza Dwianasari; Firinda, Rizma Haidif; Amalia, Ary Nahdiyani; Fuady, Rhovee Ilmiawan
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19358

Abstract

The development of antiparasitic agents derived from natural products continues to receive considerable attention due to increasing resistance and limitations of conventional therapies. This study aimed to examine the phytochemical profile of the chloroform extract of fennel leaves (F. vulgare Mill.) as a basis for antiparasitic agent development. The extract was obtained using a maceration method and analyzed using thin layer chromatography. Qualitative analysis was conducted based on the observation of visible spots after spraying with appropriate visualization reagents, while supporting analysis was performed based on the calculation of retention factor values for the detected spots. The results revealed the presence of several major groups of secondary metabolites, including flavonoids, terpenoids, alkaloids, and phenolic compounds, as indicated by specific color changes and retention factor values. The diversity of these metabolites suggests the possible involvement of multiple biochemical pathways related to antiparasitic mechanisms. Overall, the phytochemical profile of the chloroform extract of fennel leaves provides important preliminary data to support further research on natural product–based antiparasitic agents.
Acute Toxicity Test of Tamarillo Fruit Ethanol Extract (Solanum betaceum Cav.) on the Levels of Liver Transaminase Enzymes in Male Wistar Rats Amalia, Ary Nahdiyani; Yulianti, Rini Dwi; Khumaeni, Eko Hidayaturrohman; Hardiningsih, Denok Tri
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19413

Abstract

Indonesians traditionally utilize tamarillo for its various health benefits. However, the lipophilic compounds it contains have the potential to cause hepatotoxicity and increase transaminase enzymes, namely SGPT and SGOT enzymes. The study aimed to test the toxicity of tamarillo ethanol extract acutely on SGPT and SGOT levels in male Wistar white rats. The study used a post-test only experimental design with a control group design. Fifteen rats were randomly divided into five treatment groups. Group K1 as a control was given distilled water, group K2 was given paracetamol 2.5 g/kgBW, while groups K3, K4, and K5 were each given tamarillo ethanol extract in single doses of 200, 400, and 600 mg/kgBW. After 24 hours, rat blood serum samples were taken through the orbital sinus to measure SGPT and SGOT levels using the UV test method. The results showed that the average SGPT levels increased in the K2 group by 295.34±13.31 U/L and K5 by 93.67±19.03 U/L. Meanwhile, the average SGOT levels increased in the K2 group by 874±25.06 U/L, K4 by 164.67±7.57 U/L and K5 by 213.34±13.50 U/L. The One-Way ANOVA test showed a significance value of p=0.000 in the K2 and K5 groups for SGPT, while SGOT in the K2, K4 and K5 groups. Administration of tamarillo ethanol extract can cause liver damage at doses of 400 mg/kgBW and 600 mg/kgBW.
Characteristics of Presbycusis Patients at RSUD Prof. Dr. Margono Soekarjo Purwokerto Abdurrohman, Mukhammad Ilham; Kusdaryanto, Wahyu Dwi; Amalia, Ary Nahdiyani; Darmawan, Anton Budi; Nur Hestiyani, Rani Afifah
Medical and Health Journal Vol 5 No 2 (2026): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2026.5.2.19511

Abstract

Presbycusis is a progressive sensorineural hearing loss commonly affecting the elderly and significantly reducing quality of life. RSUD Prof. Dr. Margono Soekarjo Purwokerto, as a referral hospital, treats a large number of elderly patients, making characterization of presbycusis patients essential. This study aimed to describe the characteristics of presbycusis patients based on age, sex, occupation, comorbidities, and degree of hearing loss. A descriptive quantitative study with a retrospective approach was conducted using total sampling of presbycusis patients at the ENT outpatient clinic from 2022 to 2024. A total of 81 patients met the inclusion criteria. Most patients were male and aged 61–74 years. The most common occupation was farmer, and hypertension was the most frequent comorbidity. Hearing loss was generally bilateral with moderate to moderately severe degree.