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All Journal Quagga Prima: Jurnal Pendidikan Matematika Jurnal Ilmiah Jophus: Journal of Pharmacy UMUS Medfarm: Jurnal Farmasi dan Kesehatan Enggang: Jurnal Pendidikan, Bahasa, Sastra, Seni, dan Budaya Jurnal EduHealth Stigma : Jurnal Matematika dan Ilmu Pengetahuan Alam Unipa International Journal of Multidisciplinary Research and Literature (IJOMRAL) Jurnal Farmasetis Jurnal Mahasiswa Ilmu Kesehatan Jurnal Abdimas Indonesia Quagga: Jurnal Pendidikan dan Biologi Jurnal Penelitian Sains dan Kesehatan Avicenna International Journal Of Health And Social Behavior
Miranti, Indira Pipit
STIKES Ibnu Sina Ajibarang
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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EFFECT OF INFUSION OF A COMBINATION OF TEMU IRENG, TEMULAWAK, KENCUR, GINGER ON ERYTHROCYTE COUNT AND HEMATOCRIT LEVELS IN ANEMIA WHITE RATS Miranti, Indira Pipit; Khumaeni, Eko Hidayaturrohman; Maghfira, Windy Risa; Gunawan, Gunawan; Kusuma, Jaka Wijaya
International Journal of Multidisciplinary Research and Literature Vol. 4 No. 1 (2025): INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH AND LITERATURE
Publisher : Yayasan Education and Social Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53067/ijomral.v4i1.288

Abstract

Anemia is a condition in which the body experiences a decrease in hemoglobin levels, erythrocyte count, and hematocrit levels. The rhizomes of temu black, temulawak, kencur and ginger, contain compounds that have antioxidant and anti-inflammatory activities that can prevent and repair damage from oxidative stress in the body that causes anemia. This study aims to determine the effect and optimal frequency of infusion administration of a combination of temu ireng, temulawak, kencur, and ginger on erythrocyte count and hematocrit levels in white rats of the wistar strain anemia. The method used is experimental research with a pre-post-test control design. The four rhizomes used in this study contribute to the treatment of anemia. The isoflavone content in black temu and curcumin in curcumin in curcumin can prevent damage to erythrocytes due to oxidative stress of sodium nitrite exposure. Other ingredients such as Ethyl p-methoxycinnamate in ginger act as an anti-inflammatory by reducing the production of cytokines IL-1 and TNF-ɑ. Then the content of 6-gingerol in ginger can stop the formation of hepcidin which inhibits the absorption of iron, so that the process of forming red blood cells can continue in the bone marrow. It can be concluded that the combination of infusion of temu black, temulawak, kencur and ginger can increase the number of erythrocytes and hematocrit levels in anemia white rats. Meanwhile, the optimal frequency in increasing the number of erythrocytes and hematocrit levels occurred in the P2 group with a frequency of administration 2 times a day.
Studi Etnobotani Tanaman Berkhasiat Obat untuk Pengobatan Tradisional Anti, Sri; Dewi, Iva Rinia; Supriani, Supriani; Kholid, Rofik; Miranti, Indira Pipit; Ramadhan, Muhamad Fauzi
Jurnal Farmasetis Vol 13 No 4 (2024): Jurnal Farmasetis: November 2024
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/far.v13i4.2343

Abstract

Etnobotani merupakan ilmu yang mempelajari tentang tanaman dan interaksi   antara manusia dan  sumber daya tanaman yang digunakan oleh manusia. Tanaman berkhasiat obat merupakan tanaman yang digunakan untuk obat, baik yang ditanam secara langsung maupun secara liar berdasarkan pengalaman dengan bagian-bagian tanaman yang dapat digunakan antara lain akar, batang, biji, buah, bunga, daun, kulit, rimpang, seluruh bagian, dan umbi. Penelitian ini bertujuan untuk mengetahui jenis, khasiat, dan cara pengolahan tanaman berkhasiat obat oleh masyarakat Desa Pekuncen. Penelitian dilakukan di Desa Pekuncen Kecamatan Jatilawang Kabupaten Banyumas. Jenis penelitian Deskriptif Kualitatif. Metode yang digunakan adalah metode observasi dan wawancara dengan mendiskripsikan hasil pengamatan tentang pemanfaatan tanaman berkhasiat obat. Sampel yang digunakan sebanyak 95 orang responden dari masyarakat Desa Pekuncen Kecamatan Jatilawang, Kabupaten Banyumas dengan teknik purposive sampling. Responden terdiri dari terdiri dari dukun bayi, dukun pijat, orang yang dituakan atau sesepuh desa, penjual jamu, dan masyarakat umum. Berdasarkan wawancara yang dilakukan, terdapat 101 jenis tanaman berkhasiat obat yang digunakan oleh masyarakat. Jenis tanaman yang sering digunakan adalah kunyit 9,51%. Jenis penyakit banyak dijumpai oleh masyarakat diantaranya batuk, maag, demam, diare, pegal-pegal, hipertensi dan asam urat. Pengolahan tanaman yang sering dilakukan adalah direbus 56,64%.
FORMULASI SEDIAAN PACTH ANTIPIRETIK EKSTRAK ETANOL RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb.) cahyani, arinda Nur; Miranti, Indira Pipit; Dewi, Iva Rinia; Susanto, Adi; ., Ma'rifah
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 13 No 2 (2024): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v13i2.417

Abstract

Demam adalah suatu keadaan dimana terjadi peningkatan suhu tubuh diatas normal, dikatakan demam jika suhu tubuh berada >37,5 OC. Temulawak (Curcuma xanthorrhiza Roxb.) mempunyai kandungan senyawa flavanoid yang telah dikenal memiliki efek antipiretik yang bekerja sebagai inhibitor enzim cyclooxygenase (COX) yang berperan dalam pembentukan prostaglandin. Penelitian ini bertujuan untuk memformulasikan sediaan patch ekstrak rimpang dan menguji efektivitasnya sebagai antipiretik. Jenis penelitian ini adalah ekperimental dengan metode variasi konsentrasi ekstrak rimpang temulawak (F1=0,45 gram; F2= 0,75 gram) serta pengujian efek antipiretik yang dilakukan dalam penelitian ini adalah induksi pepton sebanyak 1 ml secara intraperitoneal pada tikus. Hasil penelitian menunjukan kedua formulasi F1 dan F2 untuk uji organoleptik memiliki warna, bau, dan bentuk yang sama (warna keorange an, bentuk transdermal, dan bau khas temulawak); untuk uji homogenitas, susut pengeringan, ketebalan patch dan uji efektivitas antipiretik patch memenuhi persyaratan. Namun pada uji ketahanan lipatan patch belum memenuhi persyaratan yaitu >200 kali lipatan. Berdasarkan hasil tersebut patch rimpang temulawak belum memenuhi syarat dibuatnya sediaan patch, dikarenakan patch belum memenuhi syarat uji ketahanan lipatan. Uji efektivitas antipiretik diperoleh pada konsentrasi F1 = 0,45 gram ekstrak rimpang temulawak memiliki efektivitas antipiretik sebesar 36,1±0,3 OC dengan presentase penurunan demam sebesar 0,28% pada menit ke-60.
Optimization of Mannitol-Sucrose Mixture in Lozenges Containing Temu Ireng, Curcuma, Sand Ginger, and Ginger Using the SLD Method Arinda Nur Cahyani; Eko Hidayahturrohman Khumaeni; Indira Pipit Miranti; Iva Rinia Dewi; Yosi Soraya
International Journal of Health and Social Behavior Vol. 1 No. 4 (2024): November : International Journal of Health and Social Behavior
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhsb.v1i4.462

Abstract

Reduced appetite, diarrhea, cough, and joint pain are common health issues. Traditional medicinal plants such as Temu Ireng, Curcuma, Sand Ginger, and Ginger have been used to treat these conditions. This study aims to optimize the formulation of lozenges containing these plants using a combination of mannitol and sucrose as excipients through the SLD (Simple Lattice Design) method. Five formulations with varying ratios of mannitol and sucrose (FI = 75:25, FII = 25:75, FIII = 100:0, FIV = 0:100, FV = 50:50) were prepared using wet granulation. Granule physical properties were evaluated, and the optimum formulation was identified using statistical analysis including normality tests and one-sample t-tests. The results indicated that FI (mannitol 75%, sucrose 25%) provided the most desirable characteristics, with excellent granule flow, compressibility, and uniformity in lozenge quality. This research contributes to the development of herbal lozenges with optimized excipient combinations, enhancing the efficacy and quality of traditional medicine products.
EFEK PEMBERIAN INFUSA KOMBINASI TEMU IRENG, TEMULAWAK, KENCUR DAN JAHE TERHADAP BERAT MENCIT GALUR SWISS-WEBSTER Indira Pipit Miranti; Arinda Nur Cahyani; Eko Hidayaturohman; Ninstar Fathina Rifa
STIGMA: Jurnal Matematika dan Ilmu Pengetahuan Alam Unipa Vol 18 No 01 (2025)
Publisher : Universitas PGRI Adi Buana Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/stigma.8.01.10354.%p

Abstract

Signs that children have difficulty eating and will then trigger malnutrition are very limited nutritional intake and a reduced appetite. Temu ireng, curcuma, sand ginger and ginger rhizomes contain essential oils, curcumin, xanthorizol, gingerol and flavonoids in each plant which can increase body weight and appetite. The purpose of this study was to determine the effect and optimal frequency of infusion combination on body weight and feed consumption of mice. The research was conducted in the Pharmacology Laboratory of STIKes Ibnu Sina Ajibarang. This type of research is true experimental with pre-post-test control design method. 28 male mice were divided into four groups. Group P0 (aquadest), group P1 (½ x dose), group P2 (1x dose) and group P3 (1 ½ x dose). All treatment groups were acclimatized for 7 days, then treated according to the predetermined dose, then observed body weight gain and feed consumption for 28 days. Data analysis was conducted using paired t-test, One Way ANOVA test, and Post-hoc LSD test. The results showed that there was a significant effect on body weight gain in group P2 (p=0.000) and feed consumption in all groups in the first, third and fourth weeks. (p<0,05).   Keywords; Effect, Body Weight, Infusa, Rhizome.
Penyusunan Kamus Elektrik Leksikon Jenis Tuturan “Rasa Sakit” Dalam Konteks Etnolinguistik Dialek Banyumasan Sebagai Bahan Pembelajaran Etnofarmakologi Wilda Putri Festiyanti; Indira Pipit Miranti
ENGGANG: Jurnal Pendidikan, Bahasa, Sastra, Seni, dan Budaya Vol. 1 No. 2 (2021): Juni: Jurnal Pendidikan, Bahasa, Sastra, Seni, dan Budaya
Publisher : FKIP, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/enggang.v2i2.8928

Abstract

"The preparation of an electric lexicon dictionary of the speech type 'pain' in the ethnolinguistic context of the Banyumasan dialect as EthnoPharmacological Learning material" is scheduled to be carried out in several stages of research, because it is not possible to do it in one complete study. The main objective of this first research in a series of studies that produced the final result in the form of an electric dictionary was to begin with collecting/recording lexicons of types of pain speech using a combined method of observation, interviews and documentation. The researcher goes directly into the community so that he can see and observe naturally how the lexicons of the speech type 'pain' are pronounced in society. The target of interviews and observations was the community in the Banyumas residency area which was limited to only Banyumas, Purbalingga and Cilacap as respondents for this first study. Using the full sampling data collection technique, 103 lexicons of the type of 'pain' speech were obtained according to the part of the body that feels the pain. Then, each of these lexicons is translated into Indonesian and there is a pain lexicon that cannot be translated directly into Indonesian. This proves that the Banyumasan Javanese dialect has a more detailed and complete lexicon/vocabulary than Indonesian and deserves to be preserved as one of the regional languages ​​with a large number of speakers on the island of Java
Implementasi Program Kuliah Kerja Nyata (KKN) INSANI dalam Meningkatkan Potensi Masyarakat Desa Papringan, Banyumas Pipit Miranti, Indira; Melati, Putri; Saputra, Aji; Fajriatul, Ficki; Diyanatur, Asa; Setyawati, Muji; Latifah, Umi; fatkhurrokhman; suripno
jurnal ABDIMAS Indonesia Vol. 3 No. 3 (2025): Jurnal ABDIMAS Indonesia
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jai.v3i3.3396

Abstract

Kegiatan Kuliah Kerja Nyata (KKN) merupakan salah satu implementasi Tri Dharma Perguruan Tinggi yang berorientasi pada pemberdayaan masyarakat. Penelitian ini bertujuan untuk mengevaluasi pelaksanaan program KKN INSANI (Inovasi dan Solusi untuk Pembangunan Masyarakat) di Desa Papringan, Banyumas. Program difokuskan pada empat bidang utama, yaitu sosial, ekonomi, kesehatan, dan teknologi informasi. Metode yang digunakan mencakup observasi lapangan, diskusi bersama komunitas, pelaksanaan program, serta evaluasi hasil kegiatan. Hasil penelitian menunjukkan adanya peningkatan keterampilan masyarakat dan penguatan kapasitas sumber daya manusia, terutama dalam mengoptimalkan potensi desa melalui kegiatan edukasi, pelatihan, dan inovasi berbasis lokal. Temuan ini menegaskan bahwa program KKN INSANI tidak hanya memberikan manfaat langsung bagi masyarakat, tetapi juga menjadi media pembelajaran kolaboratif bagi mahasiswa dalam mengasah kemampuan komunikasi, problem solving, dan kepemimpinan sosial. Dengan demikian, program ini berkontribusi terhadap pengembangan desa yang berkelanjutan sekaligus memperkuat peran perguruan tinggi dalam pembangunan masyarakat.
Antibacterial Effectiveness Test of Ethanol Extract of Gadung Mango Leaves Against Staphylococcus aureus and Escherichia coli Bacteria Indira Pipit Miranti; Vivin Andriani
Quagga: Jurnal Pendidikan dan Biologi Vol 16 No 1 (2024): QUAGGA : Jurnal Pendidikan dan Biologi
Publisher : Program Studi Pendidikan Biologi, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25134/quagga.v16i1.74

Abstract

Infection is a disease that often occurs in Indonesia. This disease is caused by pathogenic microbes, one of which is bacteria. Staphylococcus aureus and Escherichia coli are bacteria that cause infection. Pharmacological therapy for bacterial infections used to use antibiotics, currently tends to use drugs that come from nature. One of the plants that has the potential as an antibacterial is gadung mango leaves. This study aims to determine the effectiveness of mango leaf ethanol extract against S.aureus and E.coli bacteria. The method used was well diffusion with concentrations of ethanol extract of mango leaves 0.5% (S1), 0.75% (S2), 1% (S3), streptomycin (K+), and ethanol (K-), respectively treatment was repeated 5 times. Data that can be analyzed using One Way ANOVA with a significant level of 0.05. Based on the results of the antibacterial extract of ethanol extract of mango gadung leaves, it has the potential to be better on E. coli bacteria, namely at a concentration of 1% (S3) of 16.05 mm, whereas on S.aureus K+ bacteria (Streptomycin) it is better on control + of 15.9 mm.
Co-Authors ., Ma'rifah Adi Susanto Adi Susanto Aji Saputra, Aji Amalia Difa Lestari Amalia, Ary Nahdiyani Andika Adi Prasetya Anisa Annastasya Anti, Sri Arinda Nur Cahyani Dewi, Iva Rinia Diyanatur, Asa Eka Setyaningsih Eko Hidayahturrohman Khumaeni Eko Hidayaturohman Eko Hidayaturrohman Khumaeni Fajriatul, Ficki fatkhurrokhman Febia Citraeni Gunawan Gunawan Gunawan Gunawan Ikha Maulana Dewi Irfan Saeful Hidayat Iva Rinia Dewi Jaka Wijaya Kusuma Kholid, Rofik Khumaeni, Eko Hidayaturrohman lfha Tanesha Fitri Lina Nur Halisa Lukmanul Akhsani Maghfira, Windy Risa Melati, Putri Najiyah Nur Adilah Nanda Yayu Nur Fajri Ninstar Fathina Rifa Novita Lia Kartini Qonita Nawal Ifada Ramadhan, Muhamad Fauzi Ratih Widiyanti Rini Dwi Yuliana Sekar Mufathul Azrifah Setyawati, Muji Shabrina Tsabbatani Silviyani, Silviyani Supriani, Supriani Suripno Umi Latifah Vivin Andriani Wilda Putri Festiyanti Yosi Soraya Yusak Wijaya Y