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All Journal Medula Jurnal EduHealth Room of Civil Society Development Prosiding Dedikasi: Pengabdian Mahasiswa Kepada Masyarakat Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Room of Civil Social Development
Evi Kurniawati
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Arts Humanities Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Medula

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Perbedaan Penyembuhan Luka Bakar Derajat II antara Pemberian Topikal Ekstrak Sel Punca Mesenkimal Wharton’s Jelly Tali Pusat Manusia dan Moist Exposed Burn Oitment (MEBO) pada Tikus Putih Jantan (Rattus Norvegicus) Galur Sparague Dawley Eka Lestari; Evi Kurniawati; Fitria Saftarina
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.88

Abstract

Abstract Moist Exposed Burn Ointment (MEBO) is an ointment which can accelerate burn healing. Wharton's jelly mesenchymal stem cell (WJMSc) extract in human umbilical cord has the ability to potentially assist the burns healing process. This research was a laboratory experimental study with the use of 27 white rat induced with second degree burns and was divided into a control group (K1), Moist Exposed Burn Ointment (MEBO) group (P1) and WJMSc (P2) group. Observation of burn healing rate used healing time and burn diameter was conducted for 28 days. Data were analyzed using One way ANOVA and Kruskal wallis statistic test with 5% of α value. Average burn healing rate of K1 group: 26,78 days, P1: 24,56 days, P2: 19,67 days with the result of burn healing rate data analyzed test is p:0,005. Differences in burn diameter occurred on day 8, 12, 16, 20 and 24 on the ploriferation and remodeling stage with the result of burn diameter data analyzed test is p<0,05. Conclusion: There was a significant difference on the speed of burn healing and burn diameter between treatment group with p: 0,001. WJMSc is the fastest therapy and the largest diameter cutback.
Obstruksi Saluran Nafas Atas grade III ec Kassabach Merrit Syndrome + Bronchopneumonia+DIC Intanri Kurniati; Risti Graharti; Agustyas Tjiptaningrum; Evi Kurniawati
Medula Vol 12 No 3 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i3.346

Abstract

Upper airway obstruction is a blockage in the larynx caused by inflammation, foreign bodies, trauma, tumors so that ventilation is disrupted. One of the causes is hemangioma, which is the most common soft tissue tumor in newborns. In the state of hemangiomas, sometimes also found a syndrome in the form of Kasabach-Merritt Syndrome. As many as 20% of patients with KMS exhibit unusual symptoms compared to cutaneous hemangiomas. Clinical symptoms that can occur in upper respiratory tract obstruction include hoarseness, dysphony to aphony, shortness of breath (dyspnea), stridor (breath sounds) inspiration, suprasternal, epigastric, supraclavicular and intercostal retractions on inspiration. Kasabach-Merritt Syndrome is rare because the diagnosis is often delayed. KMS is more common in boys than girls. Ultrasound examination, Computer Tomography (CT) Scan, Magnetic Resonance Imaging (MRI) can help to determine the nature and extent of the lesion and identify the involvement of organs in the body. Extensive bleeding in KMS can cause consumptive coagulopathy that occurs due to excessive use of coagulation factors such as fibrinogen. Coagulopathy will progress to Disseminated Intravascular Coagulation (DIC) and even death. From this condition, the patient also experienced bronkopneumonia which is an acute infection of the lungs affecting the lung lobules starting from the lung parenchyma which can be caused by various etiologies such as bacteria, viruses, fungi and foreign bodies. This is because patients have a susceptibility to infection due to their condition.
Co-Authors Agustyas Tjiptaningrum Anisa Riana Putri Annisa Destiyawati Asih Imulda Hari Purwani Dicky Irawan Adinyoto Dwi Wahyuni Eka Lestari Esti Ambar Widyaningrum Fita Sari Fitria Saftarina Ida Kristianingsih Intanri Kurniati KRISNA KHARISMA PERTIWI Lestari, Tri Puji Nadia Pramasari Puji Lestari, Tri Risti Graharti Sandy Apriliza Tri Puji Lestari