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All Journal HAYATI Journal of Biosciences Sistemasi: Jurnal Sistem Informasi Jurnal Farmasi Tinctura Jurnal AFAMEDIS Jurnal Manuhara: Pusat Penelitian Ilmu Manajemen Dan Bisnis Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Fita Sari
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Agriculture, Biological Sciences & Forestry Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Electrical & Electronics Engineering Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Uji Aktivitas Tonikum Ekstrak Etanol Daun Seledri (Apium graveolens L.) Metode Natatory Exhaustion Rosa J. Hesturini; Fita Sari; Aqvila Putri Vadia
Tinctura Vol 4 No 1 (2022): Jurnal Farmasi Tinctura
Publisher : Program Studi S1 Farmasi Fakultas Ilmu Kesehatan Universitas Ibrahimy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35316/tinctura.v4i1.2344

Abstract

Fatigue syndrome menunjukkan karakter kelelahan yang intens dengan durasi lebih dari enam bulan dan berhubungan dengan berbagai gejala pada pasien. Kelelahan ini tidak pulih setelah tidur malam dan dapat mengganggu aktivitas sehari-hari sebanyak 50% (Fernández et al., 2009). Penggunaan tonikum untuk mengurangi gejala sindrom ini menjadi salah satu pilihan masyarakat. Tujuan penelitian ini adalah untuk mengetahui adanya aktivitas tonikum beserta dosis optimum ekstrak etanol Daun Seledri (Apium graveolens L.) secara in vivo. Metode penelitian yaitu dengan mengujikan ekstrak etanol 96% pada 25 ekor mencit yang terbagi dalam 5 kelompok. Kelompok kontrol negatif CMC Na 0,5%, kontrol positif kafein 100 mg/KgBB, kelompok ekstrak daun seledri 100 mg/KgBB, 200 mg/KgBB dan 400 mg/KgBB diberikan secara peroral. Pengujian dilakukan dengan metode natatory exhaustion. Analisis data dilakukan dengan cara membandingkan waktu berenang sebelum dan sesudah perlakuan dan disajikan dalam presentase. Hasil penelitian menunjukkan ekstrak etanol daun seledri dosis 400 mg/KgBB memiliki aktivitas tonikum paling tinggi sebesar 30,35% sedangkan kontrol positif kafein menunjukkan aktivitas tonikum sebesar 23,44%. Hal ini diduga kerena adanya berbagai senyawa yang dapat bersinergi meningkatkan aktivitas tonikum.
Faktor Yang Mempengaruhi Tingkat Kepatuhan Pasien Terhadap Penggunaan Obat Antihipertensi Di Puskesmas Tarik Periode Maret-April 2023 fita sari; Eko Yudha Prasetyo
Jurnal Farmasi Indonesia AFAMEDIS Vol. 4 No. 2 (2023): AFAMEDIS || JURNAL FARMASI INDONESIA
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hypertension or high blood pressure is an increase systolic blood pressure of more than 140 mmHg and diatolic blood pressure of more 90 mmHg on two measurement with an interval od five minutes in a state of sufficient rest. The succes of treatment in hypertension patient is influenced bye several factors, one of which is adherence to medication. Factors that influence the level of patient compliance include knowledge, motivation for treatment, and family support. The design of this study used a descriptive analytic with a cross sectional study approach, data collection was carried out by giving questionaires and conducting interviews to patient who met the criteria. The result showed that the factor that influenced the level of patient compliance were education, employment status, duration of suffering from hypertension, participation of health inscurance, level of knowledge, affordability of acces to health service, family support, and the role of health workers and motivation for treatment.
Antioxidant, Antidiabetic, and Antibacterial Activities of Terminalia bellerica Seed Extracts in Various Solvent Polarities Atmira Sariwati; Fita Sari; Venty Suryanti; Desi Suci Handayani; Ichiro Kamei; Ninis Yuliati
HAYATI Journal of Biosciences Vol. 31 No. 5 (2024): September 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.5.854-866

Abstract

Terminalia bellerica is well-known for producing edible fruits with pharmacotherapeutic properties. Traditional healers use these species to treat and control diabetes mellitus, its side effects, and other illnesses. Involved in this disease's pathophysiological process, extensive research has been conducted to validate and comprehend these bioactive claims scientifically. This research aims to ascertain the bioactive metabolite contents of different solvent polarities, including ethyl acetate, hexane, distilled water, and methanol. The phenol concentration was determined using the Follin-Ciocalteu procedure to be between 23.45 and 160.41 mg GAE/g. The aluminum chloride colorimetric technique measured flavonoid concentration from 88.52 to 7.12 mg QE/g. The quantitative values of tannic acid, which spanned from 0.78 to 5.32 mg TAE/g, were determined by spectrophotometry UV-VIS. The extracts' capacity to reduce free radical damage ABTS (2, 2' azinobis (3-ethylbenzene-thiazoline-6-sulfonic-acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl) was examined. The extract ethyl acetate exhibited the most significant level of antioxidant activity, with IC50 values for DPPH and ABTS of 28.17 and 22.22 g/ml, respectively. Staphylococcus aureus (23 mm) and were tested for antibacterial and antifungal activity in a methanol extract (21 mm). In vitro, antidiabetic activities were assessed using α-glucoside and α-amylase inhibition. The ethyl acetate extract has α-glucoside inhibition IC50 of 23.04 g/ml and α-amylase inhibition IC50 of 25.35 g/ml. T. bellerica seed includes secondary metabolites that show promise as lead chemicals in creating potent medications.
People Counting for Train Temperature Control using You Only Look Once v5 Method Fita Sari; Wahyu Pribadi; Adiratna Ciptaningrum
Sistemasi: Jurnal Sistem Informasi Vol 13, No 4 (2024): Sistemasi: Jurnal Sistem Informasi
Publisher : Program Studi Sistem Informasi Fakultas Teknik dan Ilmu Komputer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32520/stmsi.v13i4.3248

Abstract

AC (Air Conditioner) is an air conditioning system that is used anywhere, one of them on the train. Air conditioning is also a major factor in the comfort level of train passengers. However, train air conditioning currently can only be controlled manually from the driver's cabin so that the number of passengers does not affect the air conditioning temperature. What's more, the air conditioner absorbs 30% of the total power in the train. Therefore, this research was compiled with the aim of being able to calculate the number of passengers through the concept of people counting using the You Only Look Once (YOLO) method for the train's temperature control system. This research was built using 1 object class, namely person and the YOLOv5 algorithm, where this method is an object detection method with a high degree of accuracy. This research was designed using the Python programming language with the Google Colaboratory platform and MQTT for the data storage protocol for passenger detection results. The dataset used is passengers in the train as many as 1300 images. The training and validation results model obtained a 99.63% mAP, 95% precision, 100% recall, 97.5% F1 score, and 79.96% average IoU. Then, the model was tested and obtained 99.35% mAP, 95% precision, 99% recall, and 97% F1 score. This research resulted in a fairly good system performance in detecting and counting passengers on trains.
UJI STABILITAS DAN UJI HEDONIK MASKER GEL PEEL-OFF EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) DENGAN VARIAN KONSENTRASI POLIVINIL ALKOHOL (PVA) SEBAGAI FILMING AGENT Tri Puji Lestari; Anisa Riana Putri; Ida Kristianingsih; Evi kurniawati; Fita Sari
Jurnal Ilmiah Manuntung Vol 8 No 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.639

Abstract

Research on the Formulation Physical Stability Test and hedonic test of the peel-off gel mask of binahong Leaf Extract has been conducted. This study aims to determine the best formula of the binahong Leaf Extract peel-off gel mask preparation with PVA as a filming agent. The steps of the procedure in this research include plant determination, sample preparation, making binahong leaves simplicia, making binahong leaves extract, formulation of peel off gel mask evaluation of physical properties, stability test, irritation test and hedonic test. Formulation of binahong Leaf Extract peel-off gel mask were carried out in three formulas with various variations of PVA concentrations of 5%, 5,5%, and 6%. The results of the physical properties test shows that peel-off extract masks of binahong leaves with different concentration variations differ in organoleptic, ph test, and drying time test a statistical data analysis. Based on the results of the stability test using the cycling test method with temperature ± 4̊ C and ± 40̊ C over the course of six cycles. he most stable results of existing tests are F2 and F3 showed no significant differences in each evaluation. Test irritation suggests that the gel peel-off mask was not irritating. From the hedonic test results, panelists prefer F3 compared to other formulas.
AKTIVITAS ANTIBAKTERI DARI SEDIAAN GEL EKSTRAK TERPURIFIKASI KELOPAK ROSELLA TERHADAP BAKTERI Escherichia coli Fita Sari; Ida Kristianingsih; Tri Puji Lestari; Fathul Hidayatul; Yuyun Wulandari
Jurnal Ilmiah Manuntung Vol 9 No 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.674

Abstract

Natural materials had various types of primary and secondary metabolite compounds that were useful for treating a disease. Plant materials that contain high levels of secondary metabolites could be developed into raw materials for traditional medicines. An example of the development of natural medicine which was in high demand is making traditional medicinal raw materials which have antibacterial properties. These could add to the type of therapy for a disease with smaller side effects. The aim of this study was to determine the activity of the purified extract gel preparation of rosella petals as an antibacterial. The extract was obtained from the maceration method which was then followed by purification. The antibacterial activity test in this study used the well diffusion method. Detection of metabolites by Thin Layer Chromatography (TLC) includes the stationary phase of silica GF254 and the mobile phase Toluene: Acetic acid: Formic acid (6:6:1). The concentration of purified extract of rosella petals for the formulation was 5, 15 and 25%. Data analysis was carried out with the One Way Anova test with a 95% confidence level. The results of the research that the purified extract gel preparation of rosella petals has the potential to inhibit the growth of Escherichia coli bacteria in the sensitive category at a concentration of 25%. The results of a positive phytochemical screening for flavonoid compounds were indicated by the formation of a red-orange color in the test and identification using TLC produced an Rf of 0.85 which has similarities with previous studies. The conclusion of this study was that the ETKR gel preparation with a concentration of 25% was sensitive as an antibacterial
AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN BELUNTAS (Pluchea indica L.) ETANOL 70% DAN ETIL ASETAT MENGGUNAKAN DPPH Hari Purwani, Asih Imulda; Fita Sari; Muhammad Dhika Ramadhan; Herlinda Mawardika
Jurnal Ilmiah Manuntung Vol 10 No 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.740

Abstract

Pluchea indica L. is a herbaceous plant of the Asteraceae family that has been known to the public as fresh vegetables and traditional medicine since ancient times. This study aims to determine the antioxidant activity of beluntas leaves obtained from the extraction using 70% ethanol and ethyl acetate. The identification of phytochemical screening of beluntas leaves revealed the presence of flavonoids, tanninsand alkaloids. The test of antioxidant activity was performed using the DPPH method as free radical and vitamin C as a comparison. The average IC50 value beluntas leaves in 70% ethanol solvent is 94.06 ppm, in ethyl acetate is
Pengaruh Motivasi Kerja dan Pengembangan Karir terhadap Kinerja Pegawai pada Kantor Badan Penanggulangan Bencana Daerah Kota Bima Fita Sari; Mukhlis Mukhlis
Jurnal Manuhara : Pusat Penelitian Ilmu Manajemen dan Bisnis Vol. 1 No. 4 (2023): OKTOBER: Jurnal Manuhara: Pusat Penelitian Ilmu Manajemen dan Bisnis
Publisher : Asosiasi Riset Ilmu Manajemen Kewirausahaan dan Bisnis Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/manuhara.v1i4.168

Abstract

This study aims to examine the effect of: (1) To determine the Effect of Work Motivation on Employee Performance, (2) To determine the Effect of Career Development on Employee Performance, (3) To determine the Effect of Work Motivation and Career Development on Employee Performance at the Office of the Disaster Management Agency Bima city area. The type of research used in this research is associative. The population in the study were all employees at the Regional Disaster Management Agency Office, Kota Bima, totaling 62 people and a sample of 30 people using a purposive sampling technique. Data collection techniques used are observation, literature study and questionnaires. The data analysis technique used is validity test, reliability test, classic assumption test, multiple linear regression analysis, coefficient of determination, correlation coefficient, t test and f test. The results of the research based on the t test and f test show that: (1) Work Motivation has a positive and significant effect on employee performance (2) Career Development has a positive and insignificant effect on employee performance, (3) Work Motivation and Career Development have a simultaneous effect on employee performance at the Bima City Regional Disaster Management Agency office. x
Co-Authors Adiratna Ciptaningrum Anisa Riana Putri Aqvila Putri Vadia Asih Imulda Hari Purwani Atmira Sariwati Desi Suci Handayani Eko Yudha Prasetyo Evi Kurniawati fathul hidayatul Herlinda Mawardika Ichiro Kamei Ida Kristianingsih Muhammad Dhika Ramadhan Mukhlis Mukhlis Ninis Yuliati Rosa J. Hesturini Tri Puji Lestari Venty Suryanti Wahyu Pribadi Yuyun Wulandari