Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Jurnal Sain Veteriner Jurnal Medika Veterinaria
Hennivanda, Hennivanda
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Aktivitas Ekstrak Etanol Daun Bandotan Terhadap Pertumbuhan Bakteri Vibrio sp. Isolat Ikan Lele Dumbo (Clarias gariepinus) Admi, Masda; Fitri, Khairani; Hennivanda, Hennivanda; Jamin, Faisal; Rosmaidar, Rosmaidar; Syafruddin, Syafruddin; Winaruddin, Winaruddin; Azhari, Azhari
Jurnal Sain Veteriner Vol 43, No 2 (2025): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.96568

Abstract

     Daun bandotan merupakan salah satu tanaman obat yang banyak dimanfaatkan  dalam mengobati berbagai jenis penyakit karena mengandung senyawa fitokimia yang dapat menghambat pertumbuhan bakteri seperti alkaloid, flavonoid, tanin, saponin dan steroid. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak etanol daun bandotan terhadap pertumbuhan bakteri Vibrio sp. isolat ikan lele dumbo. Pelaksanaan penelitian ini menggunakan metode Kirby Bauer disk diffusion yang diawali dengan peremajaan stok isolat bakteri pada media Nutrient Broth, reidentifikasi dengan media Thiosulfate Citrate Bile Salt Sucrose Agar dan pewarnaan Gram. Selanjutnya dilakukan uji daya hambat menggunakan media Mueller Hinton Agar. Studi ini terdiri dari 5 perlakuan yaitu ekstrak etanol daun bandotan konsentrasi 25% (P1), 50% (P2), dan 75% (P3), siprofloksasin sebagai kontrol positif dan CMC 1% sebagai kontrol negatif. Hasil penelitian menunjukkan diameter zona hambat yang terbentuk pada kontrol positif (45,13 ± 0,04mm) dua kali lebih besar dibandingkan daya hambat yang terbentuk pada ekstrak daun bandotan konsentrasi 25% (23,30 ± 0,15mm), konsentrasi 50% (24,29 ± 0,17 mm), dan konsentrasi 75% (25,29 ± 0,16mm), kontrol negatif tidak menunjukkan terbentuknya zona hambat. Kesimpulan penelitian adalah ekstrak etanol daun bandotan berpotensi dapat menghambat pertumbuhan bakteri Vibrio sp. hasil isolat lele dumbo.      
The Effectivity of Muntingia calabura L. Leaf Extract Cream on Skin Incision Wound Healing Day 7 on White Rat (Rattus Norvegicus) with Diabetes Mellitus Salim, M Nur; Masyitha, Dian; Hennivanda, Hennivanda; Aisyah, Siti; Daud, Razali; Sabri, Mustafa; Fitria, Dinda
Jurnal Medika Veterinaria Vol 17, No 2 (2023): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v17i2.36274

Abstract

Wounds are damage to tissue integrity and function that occurs in the body. High blood glucose levels in diabetes mellitus can inhibit wound healing. This study aimed to determine the effectiveness of kersen leaf extract cream (Muntingia calabura L.) on the healing process of incision wounds on the skin of white rats (Rattus norvegicus) with diabetes mellitus on day 7. The experimental animal used were 12 male white rats weighing 150-200 g, aged 2-3 months old which were induced by streptozotocin 45 mg/kg BW intraperitonially. This research method used a completely randomized design (CRD) consisting of K1 as a negative control given a cream base and distilled water, K2 as a positive control given 0,1% silver sulfadiazine cream and metformin 4.5 mg/kg BW, K3 and K4 given 5% and 15% kersen leaf extract cream and 450 mg/kg BW kersen leaf extract orally. Incision wounds were made in the paravetebral area along 2 cm with a depth of 2 mm. Wound care was performed twice a day for 7 days. ANOVA test result showed that the administration of cream and kersen leaf extract significantly affected the number of fibroblast cells, collagen, and angiogenesis. The results showed that K1 was significantly different (P0,05) from K2, K3 and K4. K3 and K4 groups had higher average numbers of fibroblast cells, collagen, and angiogenesis. The application of kersen leaf extract cream was able to increase the number of fibroblast cells, collagen, and angiogenesis so that it could accelerate the healing of incision wound on day 7 in white rats with diabetes mellitus.
Co-Authors Azhari Azhari Dian Masyitha Faisal Jamin Faisal Mustafa Fitri, Khairani Fitria, Dinda M Nur Salim, M Nur Masda Admi Razali Daud Rosmaidar Rosmaidar, Rosmaidar Siti Aisyah Syafruddin Syafruddin Winaruddin Winaruddin