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Histology and Histomorphometry of The Skin of Gallus gallus domesticus, Anas platyrhynchos and Columba livia on The Caudal Region Masyitha, Dian; Zainuddin, Zainuddin; Iskandar, Cut Dahlia; Rahmi, Erdiansyah; Sayuti, Arman; Nursalim, M; Ningrum, Aulia Putri Wahyu
Serambi Saintia : Jurnal Sains dan Aplikasi Vol 11, No 2 (2023): Serambi Saintia
Publisher : Universitas Serambi Mekkah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/jss.v11i2.7177

Abstract

The skin is an organ that functions to coat, protect and wrap the surface of the body and can maintain the balance of fluids in the body, including in birds. Aves skin can also provide a thermal insulation function. In general, the skin layers of aves consist of the epidermis, dermis and hypodermis. This study aimed to describe the histological structure and histomorphometric skin of native chickens (Gallus gallus domesticus), ducks (Anas platyrhynchos) and pigeons (Columba livia) in the caudal region. The samples used were six individuals each of. The skin of the caudal region of the sample is then processed, started from preparation to a histological preparation with a thickness of 5 m, followed by Haematoxylin-Eosin (HE) staining. The results showed that the histological structure of the skin of the three types of aves consisted of the epidermis, dermis and hypodermis with a thinner thickness than the skin of mammals. The measured histomorphometric data showed that the epidermal layer thickness of the skin of the caudal region of native chickens, ducks and pigeons was not significantly different (P0.05), there was a significant difference (P0.05) in the thickness of the dermis and hypodermis layers. It was concluded there was no difference in the histological structure of the skin of native chickens, ducks and pigeons, the skin histomorphometry of the caudal region of native chickens, the dermis and hypodermis were thicker than those of ducks and pigeons.Keywords: Skin, aves, caudal, histology, histomorphometry.
Effectiveness of Kersen Leaf Extract Cream (Muntingia calabura L.) on The 3rd Day of Incision Healing Process on The Skin of Streptozotocin Induced White Rats (Rattus norvegicus) Salim, M. Nur; Azhar, Nurul Sakinah; Masyitha, Dian; Vanda, Henni; Rosmaidar, Rosmaidar; Zainuddin, Zainuddin
Jurnal Medika Veterinaria Vol 18, No 2 (2024): J. Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v18i2.40208

Abstract

A wound is a break in the continuity of tissue, which physiologically undergoes several phases of healing: hemostasis, inflammation, proliferation, and maturation. The wound healing phase can be prolonged if one experiences metabolic disorders such as diabetes mellitus (DM). Treatment is necessary to prevent the prolongation of the wound healing phase in DM patients, one of which involves using traditional medicine, specifically cherry plants. This study aimed to determine the effectiveness of cherry leaf extract cream in the healing process of incision wounds on day 3 on the skin of white rats induced by streptozotocin. The samples used were 12 white rats, aged approximately 3 months, with a body weight of 179.25 12.64 g. The rats were injected intraperitoneally with streptozotocin at a dose of 45 mg/kg BW. After 72 hours, an incision was made in the paravertebral section with a length of 2 cm and a depth reaching the subcutaneous layer. Therapy was administered for 3 days in several groups. Group KI served as the negative control (cream base), KII as the positive control (metformin 4.5 mg/kg BW and silver sulfadiazine 0.1% cream), KIII (2 ml cherry leaf extract and topical therapy with 5% cherry leaf extract cream), and KIV (2 ml cherry leaf extract and 15% cherry leaf extract cream). The results of the average number of inflammatory cells in KI, KII, KIII, and KIV were 117.403.17; 87.878.97; 104.405.97; and 91.405.39, respectively, with P0.05. The average number of new blood vessels in KI, KII, KIII, and KIV were 1.070.64; 4.870.64; 5.800.80; and 6.001.31, respectively, with P0.05. The conclusion of this study is that the administration of cherry leaf extract and 15% cherry leaf extract cream can reduce inflammatory cell infiltration and accelerate the growth of new blood vessels
The Effectivity of Muntingia calabura L. Leaf Extract Cream on Skin Incision Wound Healing Day 7 on White Rat (Rattus Norvegicus) with Diabetes Mellitus Salim, M Nur; Masyitha, Dian; Hennivanda, Hennivanda; Aisyah, Siti; Daud, Razali; Sabri, Mustafa; Fitria, Dinda
Jurnal Medika Veterinaria Vol 17, No 2 (2023): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v17i2.36274

Abstract

Wounds are damage to tissue integrity and function that occurs in the body. High blood glucose levels in diabetes mellitus can inhibit wound healing. This study aimed to determine the effectiveness of kersen leaf extract cream (Muntingia calabura L.) on the healing process of incision wounds on the skin of white rats (Rattus norvegicus) with diabetes mellitus on day 7. The experimental animal used were 12 male white rats weighing 150-200 g, aged 2-3 months old which were induced by streptozotocin 45 mg/kg BW intraperitonially. This research method used a completely randomized design (CRD) consisting of K1 as a negative control given a cream base and distilled water, K2 as a positive control given 0,1% silver sulfadiazine cream and metformin 4.5 mg/kg BW, K3 and K4 given 5% and 15% kersen leaf extract cream and 450 mg/kg BW kersen leaf extract orally. Incision wounds were made in the paravetebral area along 2 cm with a depth of 2 mm. Wound care was performed twice a day for 7 days. ANOVA test result showed that the administration of cream and kersen leaf extract significantly affected the number of fibroblast cells, collagen, and angiogenesis. The results showed that K1 was significantly different (P0,05) from K2, K3 and K4. K3 and K4 groups had higher average numbers of fibroblast cells, collagen, and angiogenesis. The application of kersen leaf extract cream was able to increase the number of fibroblast cells, collagen, and angiogenesis so that it could accelerate the healing of incision wound on day 7 in white rats with diabetes mellitus.
The Effects of Sulphaquinoxalin in Broiler Chicken: Clinical Symptom and Anatomical Pathology Salim, M. Nur; Masyitha, Dian
Jurnal Kedokteran Hewan Vol 4, No 2 (2010): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v4i2.9805

Abstract

The clinical symptom and anatomical pathology effect of sulphaquinoxalin administration were studied in 12 male -seven days-old Hubbard broiler chickens with the weight of 85.57.83 g. The chickens were randomly dividedinto 2 groups of 6 each. The P0 group as control group just orally received aquadest and the P groups were treated 1 orally with 0.1% sulphaquinoxalin which dissolved in drinking water. The sulphaquinoxalin was administrated forseven days. At the end of experiment all chickens were sacrificed for necropsy. The results indicated that less appetite and drinking water as well as decrease of body weight (P0.01). Ptechial haemorrhagic was seen in thorax andfemur muscle, mucosa of duodenum, liver, kidney, heart, lung, and spleen. The liver, kidney, heart, and spleen were swollen.
Histology and histomorphometry of the skin in the ventral abdominal region of domestic fowl (Gallus gallus domesticus), duck (Anas platyrhynchos), and doves (Columba livia) Zainuddin, Zainuddin; Rahmi, Erdiansyah; Akmal, Muslim; Masyitha, Dian; Ismail, Ismail; Hamny, Hamny; Pratiwi, Siska; Zulkifli, Baidillah
The International Journal of Tropical Veterinary and Biomedical Research Vol 9, No 1 (2024): Vol. 9 (1) May 2024
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v9i1.40134

Abstract

This study aims to determine the histological and histomorphometric characteristics of the skin of domestic fowl (Gallus gallus domesticus), ducks (Anas platyrhynchos), and doves (Columba livia) in the ventral abdominal region. Each study sample consisted of six individuals. The samples were processed into histological preparations with a thickness of 5 m and then stained using Haematoxylin-Eosin (HE). The results showed that the histological structure of the skin of domestic fowl, ducks, and doves is relatively thin compared to the structure of mammalian skin and consists of the epidermis, dermis, and hypodermis (subcutis). The histomorphometric data analysis showed that the thickness of the epidermal layer of the skin in the ventral abdominal region of domestic fowl, ducks, and doves was not significantly different (P0.05), but there were significant differences (P0.05) in the thickness of the dermis and hypodermis. It can be concluded that a similarity exists in the histological structure of the skin of domestic fowl, ducks, and doves, but differences are observed in the histomorphometric properties of the skin in the ventral abdominal region of these birds.