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All Journal Jurnal Biologi Tropis TRANSFORMASI : JURNAL PENGABDIAN PADA MASYARAKAT Jurnal Keperawatan dan Kesehatan (JKK)
Ramanda, Galih Dwiki
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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DIVERSITY AND POTENCY MARINE BACTERIA AS SOURCE OF ANTIBIOTIC COMPOUNDS TOWRDS BACTERIA PATHOGEN Khairillah, Yuyun Nisaul; Pratama, Kharisma; Fitriagustiani, Fitriagustiani; Ramanda, Galih Dwiki; Khoirillah, Fanni; Jagad, Nur Jati; Jais, Suriadi
Jurnal Keperawatan dan Kesehatan Vol 14 No 1 (2023): Jurnal Keperawatan dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54630/jk2.v14i1.354

Abstract

Antibiotic resistance is a global problem in the health sector, which can be caused by the ease with which people can get antibiotics on the market, lack of supervision by the government regarding antibiotic consumption, inappropriate use of antibiotics, and excessive consumption of antibiotics in inappropriate communities. There is the potential for marine bacteria to produce secondary metabolite compounds, especially antibiotics, which generally come from various sources and substrates that associate with each other to produce secondary metabolites. The main substrate source for marine bacteria, known to produce secondary metabolite compounds as antibiotics, can come from sediments, sponges and seaweed. Several types of diversity of marine bacteria associated with sediment that have been identified include Aeromonas veronii, Arthrobacter sp, Bacillus sp, Chryseobacterium sp, Citrobacter freundii, Enterobacter cloacea, Flavobacterium sp, Microbacterium sp, Streptomyces tunisiensis, Streptomyces sp, Streptomyces microflavus, Stenotrophomonas sp, Pristia flexa, and Pseudomonas sp. This type of bacteria, Streptomyces sp, has the most potential activity as a new type of antibiotic. Data shows that the diversity of deep-sea bacteria producing active compounds from various substrate sources can be used as candidates for new types of antibiotics to overcome the existing level of antibiotic resistance.
Community Education: Raising Awareness and Knowledge About Japanese Encephalitis Vaccination in Community Health Center Areas Nuruniyah, Nuruniyah; Meilantika, Ayu Diana; Khairillah, Yuyun Nisaul; Ramanda, Galih Dwiki; Hastuti, Lidia
TRANSFORMASI : JURNAL PENGABDIAN PADA MASYARAKAT Vol 4, No 3 (2024): Desember
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/transformasi.v4i3.27190

Abstract

The JE virus can be transmitted from animals to humans through a vector in the form of the Culex tritaeniorhynchus mosquito. JE virus infection attacks parts of the brain and can occur because the body does not have JE-specific antibodies. Vaccination has been shown to be an effective method in preventing JE disease and is given to children aged 9 months to 15 years Metode dalam pengabdian ini yaitu dengan memberikan edukasi mengenai vaksinasi JE, dengan melakukan persiapan dan pelaksanaan yang telah disetujui oleh mitra. Adapun hasil dari setelah masyarakat diberikan edukasi tentang vaksinasi JE terjadi peningkatan pengetahuan yang dapat dilihat dari hasil kuisioner pre test pengetahuan sebesar 45% dan meningkat setelah diberikan pengetahuan sebesar 84,45%. The successful Community Service Program can be seen from the results of the level of community knowledge. The suggestion in the next service is that it can be continued with JE immunization monitoring which can be seen from the maternal and child health book, so that it can be seen whether the coverage of JE vaccination has increased from the vaccine target of the Tambelan Sampit health center.
Isolation Endophyte Bacteria from Keladi Merah (Caladium bicolor L.) as Activity Potential Antimicroba Utami, Anggraini Putri; Khairillah, Yuyun Nisaul; Jagad, Nur Jati; Ramanda, Galih Dwiki
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8814

Abstract

Since endophytic bacteria are known to generate bioactive substances with possible antibacterial qualities, they present a viable substitute for antibiotics in the fight against antibiotic resistance, especially in harmful bacteria like Staphylococcus aureus. This study aimed to isolate and identify potential endophytic bacteria from red caladium plants (Caladium bicolor L.) and evaluate their antimicrobial activity against S. aureus, a Gram-positive bacterium notorious for its antibiotic resistance. The research was conducted using the disc diffusion method to assess the inhibitory effects of endophytic bacterial isolates on S. aureus growth. The results revealed varying levels of antimicrobial activity among the isolates, with isolate CLB242 demonstrating an average inhibition zone of 16.33 mm, isolate CLB244 showing an average of 17.6 mm, and isolate CLB245 showed an inhibition zone of 4 mm. Meanwhile, other isolates did not produce any inhibition zones, suggesting possible resistance or undetectable active compounds. Certain endophytic bacterial isolates from Caladium bicolor L. exhibit promising antimicrobial activity against S. aureus, highlighting their potential as sources of novel antimicrobial agents. Further research is recommended to identification of the active isolates molecular profiles and characterization of their bioactive compounds responsible for the observed antimicrobial effects, as well as to explore their mechanisms of action and potential applications in pharmaceutical development.
Co-Authors Ayu Diana Meilantika Djaswadi Dasuki Fitriagustiani, Fitriagustiani Jagad, Nur Jati Khairillah, Yuyun Nisaul Khoirillah, Fanni Nuruniyah, Nuruniyah Pratama, Kharisma Suriadi Jais Utami, Anggraini Putri