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All Journal Jurnal Kedokteran Syiah Kuala Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Ilmu Kefarmasian Indonesia Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Farmagazine Jurnal Ekonomi Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Yusi Anggriani
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Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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Analysis Of Risk Factors For Acute Kidney Injury (AKI) With The Use Of Favipiravir And Remdesivir In Covid-19 Patients At Fatmawati Central General Hospital Nurlela Nurlela; Hesty Utami Ramadaniati; Yusi Anggriani; Ahmad Subhan
Jurnal Ekonomi Vol. 13 No. 02 (2024): Jurnal Ekonomi, Edition April - June 2024
Publisher : SEAN Institute

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Abstract

COVID-19 patients are very vulnerable to complications of Acute Kidney Injury (AKI), there are many factors causing complications one of which is kidney toxic therapy, antiviral therapy is considered potentially toxic to the kidneys because most of it is excreted through the kidneys. This study was conducted to examine the risk factor profile of AKI in COVID-19 patients taking antivirals Remdesivir and Favipiravir. This study is an observational study with a cross-sectional design at Fatmawati Hospital. The sampling method uses total sampling during the period August 2020-July 2021. The data used is medical record. Bivariate analysis uses Chi-square, and multivariate analysis uses logistic regression. a sample of 208 patients who met the inclusion criteria in the period August 2020-July 2021 in the COVID-19 isolation room of Fatmawati Hospital. 135 patients using Favipiravir, 37 identified as having an AKI event and 73 patients using Remdesivir, 19 were identified as having an AKI event. Multivariate analysis with logistic regression showed that male sex and severity of severe to critical severity significantly influenced the incidence of AKI. The use of Favipiravir and Remdesivir in COVID-19 patients is not a risk factor for AKI.
Co-Authors Ahmad Subhan Astrid Kartika Sari Chandra Widianti Desweri Muhareni Dian Ratih Laksmitawati Edwina Dharmawati Elisabeth Ninung Yuliarti Fredrick D. Purba Fredrick Dermawan Purba Herty Nur Tanty M. Kenli Kendi Tampoliu Mawaddati Rahmi MGS. Aritonang Muhammad Reza Nurlela Nurlela Okpri Meila Prasasta Sutedjo Ramadaniati, Hesty Utami Reise Manninda Sahat Saragi Tarsinah Tarsinah Tri Kusumaeni Trisna Lestari