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The Important Role of Iron, Protein and Vitamin C With the Incident of Anemia Dilantika, Charisma; Sitorus, Nova; Saebah, Nur
Journal of Indonesian Specialized Nutrition Vol. 2 No. 1 (2024): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jisn.v1i3.17

Anemia is a condition where there is a lack of healthy red blood cells. Anemia can be caused by various factors, including deficiencies of iron and vitamin C. The aim of this research is to explore the important role of iron and vitamin C in preventing and treating anemia. This research adopts a qualitative approach in its research methodology. The data collection technique used is literature study. After the data is collected, analysis is carried out in three stages, namely data reduction to identify important information, data presentation to organize relevant information, and conclusion drawing to summarize the findings and their implications. The results showed that iron, protein and vitamin C have important roles in the prevention and treatment of anemia. There is a close relationship between these three components in preventing and treating anemia. Iron deficiency is the root cause of anemia, while vitamin C and protein play a role in increasing iron absorption, thus playing an important role in preventing or treating anemia. Iron is an indispensable mineral for the body to form hemoglobin and myoglobin, which are major components in the transport of oxygen and carbon dioxide. Vitamin C as an antioxidan has a positive effect on immune function and also helps the body absorb iron more easily. So to reduce the risk of anemia, by fulfilling daily protein and then eating foods rich in vitamin C and combining them with iron sources.

Iron Absorption and its Influencing Factors to Prevent Iron Deficiency Dilantika, Charisma
Journal of Indonesian Specialized Nutrition Vol. 1 No. 1 (2023): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jisn.v1i1.2

Iron is an important nutrient, required to support tissue oxygen delivery, cell growth and differentiation regulation, and energy metabolism. Body iron levels are mainly controlled by regulation of iron absorption in duodenum and proximal jejunum, allowing absorption to be accurately matched to unregulated losses. Since iron bioavailability often reduced, dietary iron absorption is controlled by cellular and systemic factors to ensure that overall body iron levels are maintained at adequate levels. A better understanding of the mechanism for iron absorption and factors influencing its absorption and bioavailability is important to avoid iron deficiency or iron overload. There are complex regulatory frameworks managing iron absorption, transportation, storage, and recycling. It is able to provide enough iron for critical body functions and react relatively quickly as iron demands increase, but mechanisms must also be in place to restrict iron absorption once the body is overwhelmed with iron. Several factors promote and impede iron absorption, such as phytate and ascorbic acid, respectively. The danger of iron deficiency for the world's population is of great significance, it is important to introduce effective strategies to tackle this issue through nutrition programs; food iron supplements; iron medication supplements; and probiotic, prebiotic, and symbiotic approaches.

Nutrition management for preterm infants to avoid growth faltering in later days Dilantika, Charisma; Wasito, Erika; Fathiya, Dina Nurul
Journal of Indonesian Specialized Nutrition Vol. 2 No. 4 (2024): Journal of Indonesian Specialized Nutrition
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jisn.v2i4.33

Premature babies have a high risk of experiencing growth retardation due to the inability of their organs to function optimally, including in absorbing nutrients. The early period of life is a critical period that requires proper nutritional management to support optimal growth and development. This study aims to provide recommendations for optimal steps for nutritional management in premature babies so that growth retardation can be avoided. The results showed that the basic principles of preterm infant nutrition management involve strategic steps to optimally meet nutritional needs. The first step is exclusive breastfeeding, which is the best source of nutrition. If breast milk is insufficient, specialized formula milk is an important alternative. Other nutritional management includes enteral and parenteral nutrition, tailored to the infant's condition. Monitoring growth and development, food tolerance and body composition are key elements to ensure the success of the intervention. Collaboration between the healthcare team, including doctors, nurses, nutritionists and parents, is essential in this process. With a careful approach and monitoring, nutritional management can address the challenges of premature infants, providing a better chance of achieving optimal health and development in the future.

Formula Isolat Protein Kedelai dan Serat Pangan untuk Anak dengan Alergi Protein Susu Sapi: Laporan Kasus: Isolate Soy Protein with Dietary Fiber Formula in Children with Cow’s Milk Protein Allergy: Case Report Fauziah, Mira; Dilantika, Charisma; Sundjaya, Tonny; Pratiwi, Dessy; Kinesya, Edwin; Ekasiwi, Firstya Diyah
Amerta Nutrition Vol. 9 No. 3 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i3.2025.533-537

Background: Cow's milk protein allergy (CMPA) represents the most frequently encountered food allergy in pediatric populations younger than three years. Clinical presentations vary widely, including gastrointestinal (GI), respiratory, and cutaneous manifestations. Objectives: The purpose of this case report is to determine the effectiveness of an isolated soy protein formula, enriched with dietary fibre, as a dietary alternative for a child afflicted with cow's milk protein allergy (CMPA). Methods: This study presents a case report concerning a 2-week-old infant who presented with gastrointestinal (GI) symptoms, specifically watery loose stools and vomiting. Given the family and socioeconomic circumstances, neither breast milk nor an amino acid or extensively hydrolyzed formula could be provided. Consequently, the infant received an isolated soy protein formula fortified with dietary fiber. This report further includes a review of the current literature on the utilization of dietary fiber in pediatric populations. Results: The use of isolate soy protein with dietary fibre formula may offer a well-tolerated and nutritionally adequate alternative for children with CMPA, providing paediatricians, nutritionists, and the broader healthcare community with an additional dietary option. Conclusions: The use of soy isolate protein formula with additional fibre suggests a beneficial effect to improve gut microbiota diversity and may improve stool consistency for both constipation and diarrhoea. However, further large-scale studies are needed to confirm its long-term effect, efficacy, and impact on growth and gut health.

Health Education to Improve Maternal Awareness on Soy-Based Infant Formula for Individuals with Cow’s Milk Allergy in Indonesia Setiabudiawan, Budi; Surapsari, Juwalita; Kartjito, Melissa Stephanie; Sitorus, Nova; Dilantika, Charisma; Basrowi, Ray Wagiu; Jo, Juandy
Unnes Journal of Public Health Vol. 14 No. 1 (2025)
Publisher : Universitas Negeri Semarang (UNNES) in cooperation with the Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ujph.v14i1.23239

Background: Cow’s milk allergy is relatively common among Indonesian infantswho are not exclusively breastfed. Despite extensive hydrolyzed formula and aminoacid-based formula are the recommended nutrition for infants with moderate-tosevere illness, not all parents could provide those specialized formulas, presumablydue to the high cost, low availability and poor palatability. In that case, soy-basedinfant formula could be an alternative nutrition. However, it was unknown whetherIndonesian mothers were aware on that alternative nutrition. Objective: We therefore assessed the knowledge levels of mothers who participated in an online platform of PrimaKu on the usefulness of soy-based infant formula to support growthand development of children with cow’s milk allergy. Methods: The study subjectsappeared to have sufficient levels of knowledge on the usefulness of soy-based infant formula for children with cow’s milk allergy. Results: In addition, by increasing their knowledge on iron and fiber fortification in soy-based infant formula, e.g.,through regular academic presentations, mothers could be more selective in choosing alternative nutrition for children with cow’s milk allergy. Conclusion: Our studysuggested that Indonesian mothers who were active in the online platform of Primaku had sufficient levels of knowledge on the usefulness of soy-based protein formanaging children with cow’s milk allergy.

Hubungan Status Anemia, Kualitas Tidur, dan Kemampuan Kognitif pada Remaja Putri Usia 12-24 Tahun di Indonesia (Analisis Data Indonesian Family Life Survey (IFLS) 5): Hubungan Status Anemia, Kualitas Tidur, dan Kemampuan Kognitif pada Wanita Muda Usia 15-24 Tahun di lndonesia (Analisis Data Indonesian Family Life Survey (IFLS) 5) Helmyati, Siti; Fauziah, Lutfi Afida; Kadibyan, Pinaes; Sitorus, Nova Lidia; Dilantika, Charisma
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.1-9

Background: Anemia is still one of the nutrition problems in Indonesia. Women of reproductive age, including the age group 15-24 years, is a group with higher risk of anemia. Iron deficiency anemia is a common cause of anemia. Iron is one of the micronutrients that important for the body, including brain. Some studies suggest that iron deficiency is associated with sleep quality and cognitive ability. Iron has a complex effect on the dopaminergic system by being a cofactor of tyrosine hydroxylase which is part of dopamine D2 receptor function. Neuromodulation by the dopaminergic system plays an important role in sleep regulation. It can also interfere with the brain's ability to spread nerve impulses that have potential to cause several disorders, one of which is motor and cognitive disorders. Objectives: This study aims to determine the relationship of anemia status with sleep quality and cognitive abilities in young women aged 15-24 years in Indonesia based on IFLS 5. Methods: This study used cross sectional design and secondary data from IFLS 5 with subjects totaling 2016 young women aged 15-24 years. This study used chi-square as statistical test with significance level p<0.05. Results: The prevalence of anemia in young women aged 15-24 years was 39.93%. It was found that there was no relationship between anemia status and sleep quality consisting of sleep disturbance (p=0.624) and sleep quality (p=0.693) and there was no relationship between anemia and cognitive ability (p=0.702). Conclusions: Anemia status has no significant relationship with sleep quality and cognitive ability.

Indikator Biokimia untuk Identifikasi Anemia Defisiensi Besi di Indonesia: Tinjauan Literatur: Indikator Biokimia untuk Identifikasi Anemia Defisiensi Zat Besi di Indonesia Helmyati, Siti; Hasanah, Fina Cahya; Putri, Febriani; Sundjaya, Tonny; Dilantika, Charisma
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.62-70

Background: The World Health Organization (WHO) states that adolescents are at risk of developing anemia. The initial step in identifying iron deficiency anemia (IDA) is through screening. In addition, the WHO framework aims to accelerate the reduction of anemia worldwide by achieving specific goals, including an increase in anemia screening. Objectives: This study aims to determine the use of biochemical indicators in screening for the identification of IDA status in Indonesia. Methods: Literature searches were conducted in the PubMed, Scopus, ScienceDirect, and Garuda databases following the PRISMA guidelines. Articles from journals indexed in Scopus Q1 to Q4 or Sinta 1 to Sinta 3 with an experimental or observational research design in Indonesia were reviewed. Discussion: Anemia screening was performed to determine IDA status, which was measured by the following parameters: hemoglobin (Hb), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). Hb is an indicator of IDA in populations with a high prevalence of IDA. MCV is calculated by dividing hematocrit by red blood cell count. MCH refers to the average absolute hemoglobin content of the red blood cells, while MCHC refers to the concentration of hemoglobin in the red blood cells. Serum ferritin (SF) is a highly reliable and sensitive indicator for assessing iron stores and clinical status in the field. In addition, serum transferrin receptor (STfR) is a more stable indicator than serum transferrin (ST). SF can differentiate between IDA caused by anemia or chronic diseases. Conclusions: Combining hemoglobin and SF improves sensitivity and specificity in detecting the severity of IDA. STfR can also be used as an indicator for IDA. The use of the STfR and SF indicators is the best biochemical approach to IDA.

Faktor Risiko Kejadian Stunting pada Anak Usia di bawah 2 Tahun: Studi Cross-Sectional di Pulau Jawa-Indonesia dengan menggunakan Data Studi Status Gizi Indonesia Tahun 2021: Faktor Risiko Stunting pada Baduta di Pulau Jawa: Studi Cross-Sectional Menggunakan Data Studi Status Gizi Indonesia Tahun 2021 Paramita, Muthia; Helmyati, Siti; Basrowi, Ray Wagiu; Dilantika, Charisma
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.20-29

Background: Stunting is a malnutrition problem that requires attention, with a prevalence of 24.4% in 2021. As the most populous island in Indonesia, Java Island has a significant impact on the incidence of stunting. Objectives: This study aims to determine the prevalence of stunting in infants and to identify factors associated with the incidence of stunting in each province of Java. Methods: This study used secondary data from the Indonesian Nutrition Status Study (INSS) conducted in 2021 with a cross-sectional design. A logistic regression test with weighting was conducted to determine the relationship between each variable and the incidence of stunting. Results: The prevalence of stunting in infants was measured in several regions of Indonesia, including DKI Jakarta (11.9%), West Java (16.3%), Central Java (13.2%), DI Yogyakarta (12.1%), East Java (15.9%), and Banten (14.6%). Risk factors for stunting were identified in DKI Jakarta, namely economic status in quintile 1 (p = 0.001), and in West Java, namely snack consumption (p = 0.002) and economic status in quintile 1 (p < 0.001). In Central Java, the risk factor was economic in quintile 1 (p = 0.048), while in the Special Region of Yogyakarta, it was age 12-23 months (p = 0.022). In East Java, infants aged 9-11 months (p = 0.013) and 12-23 months (p < 0.001) with low (p = 0.010) and middle (p = 0.017) mother's education level and economic status in quintile 1 (p = 0.005) were found to be at risk. In Banten were male infants (p = 0.011) in rural areas (p = 0.039) and with economic status in quintile 1 (p = 0.019) were found to be at risk. Conclusions: Economic status is a risk factor for stunting on Java Island. Interventions can be targeted towards improving economic status.

Kontribusi Program Pekarangan Pangan Lestari (P2L) terhadap Upaya Percepatan Penurunan Stunting di Kabupaten Sleman: Analisis Masa Pandemi COVID-19: Kontribusi Program Pekarangan Pangan Lestari (P2L) terhadap Upaya Percepatan Penurunan Stunting di Kabupaten Sleman selama Masa Pandemi Covid-19 Renita, Renita; Helmyati, Siti; Purwaningrum, Digna Niken; Sitorus, Nova Lidia; Dilantika, Charisma
Amerta Nutrition Vol. 7 No. 3SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i3SP.2023.30-40

Background: There are disparities in the level of household food security achievements between regions and getting worse with Covid-19 pandemic which has also inhibited nutritional improvement acceleration. The P2L is one of the priority programs in maintaining community food security. However, the implementation of this program is still vulnerable to sustainability. Objectives: This study aims to examine the contribution of P2L during Covid-19 pandemic in maintaining community food and nutrition security and its role to accelerate stunting reduction in Sleman Regency. Methods: This research was a descriptive qualitative with case study approach. Sample selection used a purposive maximum variation sampling method for parties actively involved in the P2L. Data collection methods were carried out using in-depth interviews, closed question types questionnaires, documentation, and participatory observation by directly involved in group activities. Results: The P2L acted as a living food barn that can provide food during Covid-19 pandemic. Vegetables were the main commodity that were able to fulfill household needs at 60% and 40% at the medium level. Meanwhile, other food commodities had not been developed optimally in the yard. However, the P2L not only had a positive impact on improving nutrition and the household economy of KWT members, but also for vulnerable communities in the surrounding area. To accelerate stunting reduction, the results from P2L were also used to support Integrated Healthcare Center activities such as providing PMT. Conclusions: The P2L program has a positive impact for the community, but it is necessary to innovate crop-livestock-fruit integration in each area and strengthen institutions in order to make the program sustainable.

Membangun Kekebalan Tubuh: Pengetahuan tentang Peran Prebiotik dan Probiotik dalam Kesehatan Anak: Crafting Paediatric Immunity: The Science of Prebiotic, Probiotic, and Synbiotic Roles in Child Health Sutanto, Luciana Budiati; Dilantika, Charisma; Pratiwi, Dessy; Latarissa, Irma Rahayu
Amerta Nutrition Vol. 9 No. 4 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i4.2025.747-766

Background: The gut microbiota affects Children's immune system, which interacts with the immune system to support a healthy body. Prebiotics and probiotics, alongside their combination in the form of synbiotics, have demonstrated significant potential for enhancing immune health in children. Objectives: This article aims to review the role of prebiotics, probiotics, and synbiotics in supporting pediatric immune health by discusses their mechanisms of action, clinical evidence of benefits, and their impact on infection risk reduction, gut health enhancement, and improved vaccine effectiveness. Methods: A comprehensive literature review was conducted by utilizing recent studies and clinical trials on the effects of prebiotics, probiotics, and synbiotics on paediatric immune health. Discussions: Prebiotics, probiotics, and synbiotics play a crucial role in supporting paediatric immune health by optimizing gut microbiota balance and facilitating the production of beneficial metabolites, such as short-chain fatty acids (SCFAs), which subsequently strengthen gut barrier function and modulate immune responses. Prebiotics provide essential nutrients for beneficial bacteria, probiotics directly interact with immune cells, and synbiotics synergistically combine these benefits, demonstrating effectiveness in reducing infections, enhancing vaccine responses, and preventing allergies. Clinical studies highlight their potential to improve gastrointestinal health, reduce inflammation, and strengthen immunity, emphasizing their importance as safe and effective interventions for children's health. Conclusions: Prebiotics, probiotics, and synbiotics demonstrate significant potential in supporting children's immune health through mechanisms that improve gut microbiota balance and enhance immune function. Despite encouraging findings, additional research is essential to determine optimal dosages, long-term safety, and individualized strategies for their clinical application.

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