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All Journal Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Sumatera Medical Journal AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Respiratory Science Jurnal Impresi Indonesia The Journal of Society Medicine (JSOCMED)
Tarigan, Setia Putra
Division Of Thoracic Oncology, Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Sumatera Utara/Haji Adam Malik General Hospital, Medan, Indonesia.
Religion Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : The Journal of Society Medicine (JSOCMED)

 1 
The Characteristics of The General Population in Medan Undergoing Lung Cancer Screening with NARU Febiyanti, Mica; Tarigan, Setia Putra; Soeroso, Noni Novisari; Eyanoer, Putri Chairani
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.165

Abstract

Introduction: Indonesia introduced the NARU lung cancer screening form to assess individual risk levels for lung cancer, classifying them as low, medium, or high risk. This study aimed to analyze the characteristics of low, medium and high risk groups in Medan city. Methods: A quantitative, descriptive cross-sectional design was used, involving 100 individuals from primary health care facilities across 11 areas, who were evaluated using the 9-question NARU form. Evaluation concluded the individuals into low, medium, and high risk of lung cancer. Results: The  majority of the responded high-risk group for lung cancer, the majority were males aged 45-65 years. They had no personal or family history of cancer but were active smokers, worked in carcinogenic environments, and did not live in homes or environments with carcinogenic risks. Additionally, they had a history of COPD and/or TB. In the moderate-risk group, both males and females aged 45-65 years were included, with no personal or family cancer history. They were passive smokers, did not work in carcinogenic environments, and did not live in homes or environments with carcinogenic risks. None had a history of COPD or TB. In the low-risk group, the majority were females under 45 years. They had no personal or family cancer history, were non-smokers, did not work in carcinogenic environments, and did not live in homes or environments with carcinogenic risks. They also had no history of COPD or TB. Conclusion: The study concluded that in Medan, 48% of the population fell into the moderate-risk group for lung cancer, while 31% were in the low-risk group, and 21% were classified as high risk.
Thoracic CT Scan Image in Transudate and Exudate Pleural Effusion Cases at Haji Adam Malik General Hospital Medan in January - September 2024 Lokman, Yovita Belva; Putra, Dedy Dwi; Tarigan, Setia Putra; Malisie, Ririe Fachrina
Journal of Society Medicine Vol. 3 No. 12 (2024): December
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v3i12.185

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Introduction: Pleural effusion is the most common pleural disease, typically diagnosed through thoracentesis. However, thoracentesis carries risks of complications. Chest CT scans offer a non-invasive alternative to assess pleural effusion and distinguish between exudate and transudate types. Methods: This retrospective cross-sectional study was conducted on patients with pleural effusion at Haji Adam Malik General Hospital, Medan. A total of 80 patients were included. Statistical analysis was performed to evaluate the correlation between demographic, clinical, and thoracic CT findings with the type of pleural effusion. The Mann-Whitney test determined the efficacy of attenuation values in differentiating exudate and transudate. Results: Of the 80 patients, 57 (71.3%) had exudative pleural effusion and 23 (28.7%) transudative. The sample comprised 43 males (53.8%) and 37 females (46.3%), with a mean age of 48.44 ± 18.532 years (range: 2–84 years). Significant correlations were found between the etiology of pleural effusion and pleural nodules with effusion type (p = 0.000 and p = 0.023, respectively). No significant correlations were observed between age, gender, or other CT findings with effusion type (p > 0.05). Attenuation values on CT scans effectively distinguished exudative from transudative effusion (p = 0.000). A cutoff attenuation value of 17.5 Hounsfield Units (HU) demonstrated an AUC of 0.887, with 84.2% sensitivity and 82.6% specificity. Conclusions: Thoracic CT scans are effective for differentiating exudative and transudative pleural effusion. Significant differences were identified in etiology, pleural nodules, and attenuation values, supporting the use of CT imaging as a non-invasive diagnostic method
Effectiveness of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) on Life Expectancy in Non-Small Cell Lung Cancer Patients in Medan City Harahap, Putri Wulandari; Tarigan, Setia Putra; Soeroso, Noni Novisari; Ashar, Taufik
Journal of Society Medicine Vol. 4 No. 2 (2025): February
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i2.193

Abstract

Introduction: Non-small cell lung cancer (NSCLC) is strongly linked to epidermal growth factor receptor (EGFR) mutations, with tyrosine kinase inhibitors (TKIs) serving as a primary treatment. While TKIs demonstrate substantial antitumor effects, resistance differs across generations. This study evaluates the impact of first- and second-generation EGFR TKIs on the survival outcomes of NSCLC patients in Medan. Method: A retrospective cross-sectional study was conducted on 67 EGFR-positive NSCLC patients treated with TKIs between 2017 and 2022. Medical records from four hospitals-Haji Adam Malik Hospital, Elisabeth Hospital, Prof. Dr. Chairuddin Panusunan Lubis USU Hospital, and Pirngadi Hospital-were analyzed. Patients aged >18 years with EGFR mutations (exon 18, 19, or 21) and complete records were included. Survival outcomes, including Progression-Free Survival (PFS), Median Survival Time (MST), and Overall Survival (OS), were compared using the Mann-Whitney test. Results: All 67 patients received either first- or second-generation TKIs. Statistical analysis revealed that patients treated with second-generation TKIs had significantly better PFS, MST, and OS than those receiving first-generation TKIs (p < 0.05). Conclusion: This retrospective study faced limitations due to incomplete data and did not assess adverse effects. However, findings indicate that second-generation EGFR TKIs provide superior survival benefits for NSCLC patients compared to first-generation TKIs. Further prospective studies are needed to validate these results and explore the impact of treatment-related toxicity.
Co-Authors Arieta, Lydia Azizah Ghanie Icksan Buana, Indra Darren Wan-Teck Lim Dedy Dwi Putra, Dedy Dwi Dian Chayadi Elisna Syahruddin Elisna Syahruddin Elizabeth Napitupulu Erna Mutiara Erna Mutiara Erna Mutiara Evlin Suzanna Febiyanti, Mica Fotarisman Zalukhu Harahap, Putri Wulandari Hendra Taufik Hidayat Hidayat Lokman, Yovita Belva Lucia Aktalina Malisie, Ririe Fachrina Muhammad Harbi Praditya Muhammad Harbi Praditya Muntasir Abdullah Netty Delvrita Lubis Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Novia Nurul Faizah Novita Margaretta Ambarita Nurul Ramadhani Pinem, Agung Haganta Putri Chairani Eyanoer, Putri Chairani R.A Henny Anggriani Rahmat Hidayat Ritonga, Adewita Rosidah Hanum Hasibuan Rosita Juwita Sembiring Stephen Johan Prasetyo Tarigan, Amira Permatasari Taufik Ashar Wan Betty Pratiwi Yahwardiah Siregar