Articles
<![CDATA[Antibacterial and Toxicity Activities of Indonesian Herbal Medicine Extracts Used for Postpartum Treatment ]]>
<![CDATA[Wiwit Denny Fitriana]]>;
<![CDATA[Sri Banun Titi Istiqomah]]>;
<![CDATA[Devi Anggraini Putri]]>;
<![CDATA[Taslim Ersam]]>;
<![CDATA[Adi Setyo Purnomo Purnomo]]>;
<![CDATA[Nurlatifah Nurlatifah]]>;
<![CDATA[Sri Fatmawati]]>
<![CDATA[ HAYATI Journal of Biosciences Vol. 28 No. 3 (2021): July 2021 ]]>
Publisher : <![CDATA[Bogor Agricultural University, Indonesia ]]>
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DOI: 10.4308/hjb.28.3.232
<![CDATA[Postpartum treatments have been used by local women in Indonesia for some time now. One commonly used postpartum treatment is the consumption of a traditional herbal medicine called PHM-1 during the first 40 days after childbirth. In addition, a second medicine known as PHM-2 is taken for days 41-80. However, sufficient scientific evidence about the benefits of this postpartum herbal medicine does not exist. In this study, the antibacterial abilities of PHM-1 and PHM-2 therefore was evaluated and showed positive potential for both. Low IC50 values were obtained against pathogenic bacteria such as Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Rhodopseudomonas palustris, Ralstonia pickettii, and Staphylococcus epidermidis and compared with chloramphenicol as a positive control. The antibacterial activity of both PHM-1 and PHM-2 against R. pickettii had the highest inhibitory activity as evidenced by the lowest IC50 values of 11.16 and 6.26 μg/ml, respectively. Furthermore, an in vivo acute toxicity test showed that PHM-1 produced a low LD50 value of 3.28 g/kg BW for both of male and female mice. These results support the use of both PHM-1 and PHM-2 as antibacterial treatments for postpartum women.]]>
<![CDATA[The Antioxidant Activities and Phenolic Content of Improved Soybean Seeds Varieties of Different Grain Sizes ]]>
<![CDATA[Muchdar Soedarjo]]>;
<![CDATA[Suhartina Suhartina]]>;
<![CDATA[Novita Nugrahaeni]]>;
<![CDATA[Andy Wijanarko]]>;
<![CDATA[Devi Anggraini Putri]]>;
<![CDATA[Sri Fatmawati]]>
<![CDATA[ IPTEK The Journal for Technology and Science Vol 31, No 1 (2020) ]]>
Publisher : <![CDATA[IPTEK, LPPM, Institut Teknologi Sepuluh Nopember ]]>
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DOI: 10.12962/j20882033.v31i1.5961
<![CDATA[Tempe and tofu are the main product of soybean commonly consumed as a daily food for the people of Indonesia. So far, soybean is well known to be a source of protein. Indeed, soybean contains secondary metabolites resulting in antioxidant activities. Antioxidants would nullify the negative effect of reactive oxygen and, as a result, could improve and maintain human health. Improvement of awareness of Indonesian people that soybean is good for human health promotion and maintenance could be a trigger to enlarge the soybean production area and increase national soybean production. The present study was undertaken to evaluate the total phenolic content and antioxidant activity of some improved soybean varieties. The observation was done in three replicates, and the standard deviation was made. The results of the present study showed that total phenolic content and antioxidant activity, as measured by ABTS and DPPH, varied among the soybean seeds tested. The variability of total phenolic content and antioxidant activity was not caused by different seed sizes but by the different genetic background encoding for other phenotypes than the seed size. In general, antioxidant activity is positively correlated to total phenolic content. Demas and Tanggamus showed significantly higher antioxidant activity compared to the rest, including imported soybean. Therefore, Demas and Tanggamus could be used as better food sources for human health.]]>
<![CDATA[Free Radical Scavenging Activity of Chromolaena odorata L. Leaves ]]>
<![CDATA[Putri Anni Maulida]]>;
<![CDATA[Devi Anggraini Putri]]>;
<![CDATA[Sri Fatmawati]]>
<![CDATA[ IPTEK The Journal for Technology and Science Vol 30, No 3 (2019) ]]>
Publisher : <![CDATA[IPTEK, LPPM, Institut Teknologi Sepuluh Nopember ]]>
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DOI: 10.12962/j20882033.v30i3.5409
<![CDATA[Chromolaena odorata is one of the plants used by the community as traditional medicine. Some of community in Ambon, Indonesia used C. odorata leaves as wound medicine. This study aims to evaluate free radical scavenging activity from fraction of methanol extract of C. odorata. Methanol extract of C. odorata leaves is known have good free radical scavenging activity. The fractionation from methanol extract of the C. odorata leaves obtained A-E fraction, where fractions C, D and E showed inhibitory activity against DPPH radicals (2,2-difenill-1-pikrilhidrazil) with IC50 values 63,95; 64.38 and 202.15 μg/mL. Positive control, which is gallic acid, has an IC50 value of 5.29 μg/mL.]]>
<![CDATA[ANALISIS KADAR HDL PADA PEROKOK AKTIF USIA 31-35 TAHUN DI KELURAHAN KEMAYORAN BANGKALAN ]]>
<![CDATA[Yogi Khoirul Abror]]>;
<![CDATA[Devi Anggraini Putri]]>
<![CDATA[ NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 12 No 2 (2021): SPECIAL EDITION (MARET 2021) ]]>
Publisher : <![CDATA[NHM PRESS ]]>
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DOI: 10.36089/nu.v12i2.331
<![CDATA[Smoking is one of the health problems that is difficult to solve even has become a national and international problem. One of the negative effects of smoking is a decrease in HDL levels in the body. The purpose of this study was to determine the description of HDL levels in active adult smokers aged 31-35 years in RT.04 / RW.01 Mlajah Bangkalan Village. This research is a descriptive study, with a research design using cross sectional design. The variable of this study is the level of HDL in active smokers with a population of 15 respondents selected as samples using total sampling. The data collection method uses a photometer, the data obtained are then presented in a frequency distribution table. The results of research on HDL levels of active smokers mostly low HDL levels less than 60 mg / dl with 11 respondents (73.33%) .This happens because the nicotine contained in cigarette smoke will stimulate the hormone adrenaline which will consequently interfere with fat metabolism which causes HDL levels in the body decrease.]]>
<![CDATA[Antioxidant activity of Momordica charantia extracts ]]>
<![CDATA[Devi Anggraini Putri]]>;
<![CDATA[Sri Fatmawati]]>
<![CDATA[ NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 12 No 3 (2021): SEPTEMBER ]]>
Publisher : <![CDATA[NHM PRESS ]]>
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DOI: 10.36089/nu.v12i3.488
<![CDATA[Momordica charantia is one of the herbaceous plants which widely distributed at tropical and subtropical regions. M. charantia, as known as pare, has been used as Indonesian traditional medicine for the treatment of bitter stomachic, laxative, and anthelmintic. This study aims to investigate the antioxidant activity of M. charantia leaves extracts (the n-hexane, dichloromethane, ethyl acetate, and methanol extracts) by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. The result showed that the ethyl acetate extract has the highest DPPH scavenging activity with IC50 value of 233.39 μg/mL. Therefore, this study concluded that ethyl acetate extract of M. charantia leaves is recommended as an antioxidant agent.]]>
<![CDATA[Increasing students' interest and knowledge about herbs in elementary school ]]>
<![CDATA[Devi Anggraini Putri]]>;
<![CDATA[Riyadatus Solihah]]>;
<![CDATA[Rizka Efi Mawli]]>
<![CDATA[ Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol 7, No 4 (2022): November 2022 ]]>
Publisher : <![CDATA[University of Merdeka Malang ]]>
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DOI: 10.26905/abdimas.v7i4.8193
<![CDATA[Herbs is not only a potent Indonesian herbal medicine but also the ancestor tried to keep the preservation of herbs. Therefore, knowledge about herbs is important to be preserved from an early age. However, currently, the interest of Indonesian children in consuming herbs tends to decrease. The stigma that herbs is bitter is the reason why herbs is unlikeable. Based on the analysis of the demographic condition in Bangkalan, the quality of education is still low, interest and knowledge about herbs is also low. The purpose of this program is to increase students' interest and knowledge about herbs at SDN Demangan 3 Bangkalan. The methods are socializing, implementing educational games about herbs, and drinking herbs together. Furthermore, students' interest in herbs was evaluated by using a questionnaire. Meanwhile, students' knowledge about herbs was analyzed and evaluated based on the results of the pre-test and post-test. The results of the program showed that students’ interest in herbs increased by 83% after a learning media namely herbs snake ladder game was applied. In addition, students' knowledge about herbs also increased by 76% from 24 respondents. Thus, this program is recommended to increase the interest and knowledge of elementary school students about herbs.]]>
<![CDATA[Metabolit sekunder dari Muntingia calabura dan bioaktivitasnya ]]>
<![CDATA[Devi Anggraini Putri]]>;
<![CDATA[Sri Fatmawati]]>
<![CDATA[ ALCHEMY Jurnal Penelitian Kimia Vol 15, No 1 (2019): March ]]>
Publisher : <![CDATA[UNIVERSITAS SEBELAS MARET (UNS) ]]>
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DOI: 10.20961/alchemy.15.1.23362.57-78
<![CDATA[Muntingia calabura (Muntingiaceae) merupakan Jamaican cherry yang dikenal di Indonesia sebagai Kersen atau Talok. Metabolit sekunder sebagai konstituen kimia telah diisolasi dari daun, batang dan akar M. calabura. Flavonoid merupakan konstituen utama penyusun metabolit sekunder dari tanaman ini. Kelompok flavonoid telah dilaporkan memiliki efek farmakologi yang baik. Beberapa literatur melaporkan bioaktivitas M. calabura sebagai antioksidan, antidiabetes, antimikroba, antikanker, anti-inflamasi dan lain-lain. Review ini bertujuan memberikan fakta ilmiah terkait sinergitas metabolit sekunder dan bioaktivitas M. calabura yang diperlukan untuk penelitian kimia bahan alam lebih lanjut.The secondary metabolites of Muntingia calabura and its bioactivity. Muntingia calabura (Mutingiaceae) was recognized as Jamaican cherry called as Kersen or Talok in Indonesia. The chemical constituents have been isolated from leave, stem and root of M. calabura. The main chemical constituent of the secondary metabolite is flavonoid. The flavonoid group has been reported as a good source in pharmacological aspect. Most of literatures reported that M. calabura has a good bioactivity as an antioxidant, antidiabetic, antimicrobial, anticancer, anti-inflammatory and others. This review aims to provide the scientific evidences related to the synergism of secondary metabolites and the bioactivities of M. calabura for further research on natural products.]]>
<![CDATA[THE EFFECT OF Cosmos caudatus LEAVES EXTRACT ON MORTALITY OF THE BLACK CUTWORM PESTS (Agrotis ipsilon) ]]>
<![CDATA[Rizka Efi Mawli]]>;
<![CDATA[Devi Anggraini Putri]]>
<![CDATA[ BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol. 10 No. 1 (2023): August ]]>
Publisher : <![CDATA[Universitas Medan Area ]]>
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DOI: 10.31289/biolink.v10i1.9870
<![CDATA[Cosmos caudatus (Asteraceae) is one of Indonesia biodiversity which is usually used as a refugia plant on several crop fields. In Indonesia, this plant is widely consumed as salad and herbal medicine as well. The aimed of this study is to see the effect of C. caudatus leaves extract on mortality of Agrotis ipsilon known as the black cutworm pests. C. caudatus leaves were collected on Surabaya East Java, Indonesia. The leaves were extracted by using maceration technique with ethanol 96% for 3x24 hours. After that, this research was conducted by observing the effect of ethanol extract from C. caudatus leaves with a concentration of 20; 15; and 10% on each group of A. ipsilon. The mortality assessment was made by determining the quantity of the death cutworms on 24, 48, and 72 hours. The result showed that the extract significantly reduced growth of A. ipsilon with LC50 value of 13.29% at 72 hours. Therefore, C. caudatus leaves extract is recommended as a biopesticide agent.]]>
<![CDATA[PERBEDAAN KADAR ASAM URAT PADA ORANG YANG GEMAR MENGKONSUMSI KOPI DAN MEROKOK DENGAN ORANG YANG HANYA GEMAR MENGKONSUMSI KOPI ]]>
<![CDATA[Fahmi, Norma Farizah]]>;
<![CDATA[Putri, Devi Anggraini]]>;
<![CDATA[Putri, Nivia]]>
<![CDATA[ JURNAL MEDICAL P-ISSN : 2685-7960 e-ISSN : 2685-7979 Vol 2 No 1 (2020): SEPTEMBER ]]>
Publisher : <![CDATA[NHM PRESS ]]>
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DOI: 10.36089/jm.v2i1.279
<![CDATA[Uric acid is a crystal formed from the metabolism of purines. In men, gout is dangerous if more than 7 mg / dl, whereas in women 6 mg / dl. In Indonesia 35% of gout occurs in men under the age of 35 years. The purpose of this study was to analyze the differences in uric acid levels in people who like to consume coffee and smoke with people who only like to consume coffee in Mlajah Bangkalan Village. The research design used is comparative analytic. The variables in this study were uric acid levels and people consuming coffee and smoking with people consuming coffee only. The population in this study was 2,775 households in Mlajah Bangkalan Urban Village. Respondents in this study were 9 people consuming coffee and smoking, and 9 people were consuming coffee. The instrument used was POCT (Point Of Care Testing) using capillary blood. Data were analyzed using Independent Sample t Test. The results of this study indicate normal uric acid levels of people drinking coffee and smoking with an average value = 5 and the average value of uric acid levels in people only drink coffee = 4.67. The p-value = 0.587 (> from the alpha value of 0.05) so that there is no difference in the levels of uric acid levels in people who like to consume coffee and smoke with people who only like to consume coffee.]]>
<![CDATA[Aktivitas Antioksidan Kombinasi Herbal Sebagai Terapi Ibu Pascapersalinan di Madura ]]>
<![CDATA[Putri, Devi Anggraini]]>;
<![CDATA[Efi Mawli, Rizka]]>;
<![CDATA[Solihah, Riyadatus]]>;
<![CDATA[Firdaus, Nailufar]]>;
<![CDATA[Denny Fitriana, Wiwit]]>;
<![CDATA[Fatmawati, Sri]]>
<![CDATA[ JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 16 No 1 (2024): MARET ]]>
Publisher : <![CDATA[NHM PRESS ]]>
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DOI: 10.36089/job.v16i1.1994
<![CDATA[Kombinasi herbal pascapersalinan atau yang biasa dikenal sebagai jamu bersalin merupakan salah satu jamu yang dipercaya sebagai perawatan Ibu pascapersalinan di Madura. Jamu ini terdiri dari beberapa kombinasi tanaman herbal yang memiliki bioaktivitas dan efek farmakologis yang baik. Penelitian ini bertujuan untuk mengevaluasi aktivitas antioksidan empat kombinasi herbal pascapersalinan dengan metode DPPH. Hasil penelitian menunjukkan keempat kombinasi herbal memiliki aktivitas antioksidan yang baik. Kombinasi B menunjukkan aktivitas penghambatan paling tinggi mencapai 95,93%±0,005 dengan asam galat sebagai standard. Dengan demikian, kombinasi herbal tersebut direkomendasikan sebagai terapi Ibu pascapersalinan.]]>
