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All Journal Jurnal Wiyata : Penelitian Sains dan Kesehatan Meditory : The Journal of Medical Laboratory JFL : Jurnal Farmasi Lampung Jurnal Kesehatan: Jurnal Ilmu- Ilmu Keperawatan, Kebidanan, Farmasi dan Analis Kesehatan Jurnal Farmasi dan Sains Indonesia (JFSI) Medical Sains : Jurnal Ilmiah Kefarmasian INDOGENIUS Pharmacy Genius Ad-dawaa: Journal Of Pharmacy Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian
panji wahlanto
STIKes Muhammadiyah Ciamis
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Activity Test of Combination of Binahong Leaf Extract (Anredera Cordifolia) and Lemongrass Extract (Cymbopogon citratus) as Antifungal Againt Pityrosporum ovale Panji Wahlanto; M. Fadil Ramadhan
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.221

Abstract

Pityrosporum ovale is a microorganism thought to be the main cause of dandruff. Binahong and lemongrass are herbal plants that can cure various diseases. Based on usage empirical leaf binahong and lemongrass kitchen nutritious for remove dandruff, hair loss, diabetes mellitus, anti- cancer and treatment on infection skin caused by bacteria nor mushrooms. Binahong leaf extract and extract lemongrass contain metabolites secondary wrong only flavonoids. Flavonoids are effective as antimicrobials. Destination from study this The purpose of this study was to determine the antifungal activity of the combination of binahong leaf extract (Anredera cordifolia) and lemongrass extract (Cymbopogon citratus) against Pityrosporum ovale . This study used 5 test groups, which consisted of a combination group of binahong leaf extract and lemongrass F1 = concentration 50%:50%, F2 = concentration 37,5%:12,5%, F3 = concentration 25%:25% and F4 = concentration 12,5%:37,5%, and the control group was positive (ketoconazole 2%) and negative ( aquadest), with 3 repetitions. The materials used in this study were binahong leaf simplicia and kitchen lemongrass simplicia macerated using 70% ethanol solvent, resulting in a thick extract which was then tested for antifungal activity against Pityrosporum ovale by the method diffusion paper disc on Sabouraud Dextrose Agar medium . The parameter observed was the diameter of the growth inhibition zone of the fungus Pityrosporum ovale . Analysis using ANOVA (Analysis of Variance). The results of this study were binahong leaf extract and kitchen lemongrass extract positive containing flavonoid compounds. The combination of binahong leaf extract and citronella extract has the ability to inhibit the growth of the fungus Pityrosporum ovale with visible inhibition zones formed. The most effective concentration to inhibit the growth of the fungus Pityrosporum ovale was at a concentration of F1 = 50%:50% of 17.40 mm with a strong category.
Formulation and Evaluation of Moringa Leaves Extract (Moringa oleifera L. ) Lotion with Variation Concentration of Triethanolamin Marlina Indriastuti; Panji Wahlanto; Ditha Septya Utami
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.222

Abstract

The Indonesian people know the moringa plant as a plant for consumption as a vegetable, a fetid decoction as well as animal feed. However, the Moringa plant, especially in the leaves, has another benefit , namely as an antioxidant. Antioxidants in Moringa leaves contain tannins, flavonoids, saponins, alkaloids, steroids and terpenoids. The purpose of this study was to determine a good formulation for the preparation of moringa leaf extract lotion with variations in the concentration of triethanolamine. The research method used is the experimental method. Data analysis was performed using the One Way Anova and Kruskal Wallis Test statistical methods . The results showed that the organoleptic test of slightly thick texture preparations for formula I, thick texture for formulas II and III; typical preparation odor of Moringa leaf extract; the color of the preparation is yellow. Homogeneity test of formula I was not homogeneous, formula II was not homogeneous in the third replication, formula III was homogeneous. The average viscosity test for formula I was 1,800 c.Ps, formula II was 8,300 c.Ps, formula III was 1,666 c.Ps. The average pH test for formula I was 6, formula II was 7, formula III was 8. The average adhesion test for formula I was 02.76 seconds, formula II was 02.02 seconds, formula III was 01.37 seconds. The average spreadability test for formula I was 3.9 cm, formula II was 6.6 cm, formula III was 6.9 cm. Based on the evaluation results obtained, it can be concluded that the triethanolamine concentration of 2.5% produces a good formulation for lotion preparations.
Phytochemical Analysis of Flavonoids and Tannins from Ethanol Extract of Keji Beling (Strobilanthes crispus) Using UV-Vis Spectrophotometry Method Ayu Safitri; Panji Wahlanto
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 2 (2023): Ad-Dawaa: Journal of Pharmacy (November 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i2.413

Abstract

Keji Beling (Strobilanthes crispus BI.) is a plant that has been used by the community as a traditional medicine for kidney stones, diabetes mellitus, ulcers and as a laxative. Keji beling contains many beneficial substances such as flafonoids and tannins. This research aims to determine the content of flavonoid and tannin phytochemical compounds and to determine length Maximum waves in flavonoid and tannin compounds in keji beling leaf extract (Strobilanthes crispus BI.). Keji beling leaves were extracted using the maceration method with 70% ethanol solvent. Secondary metabolite content was identified qualitatively using a phytochemical screening test. Flavonoids were tested with concentrated MgSO4 and HCl reagents and tannins were tested with FeCl3 reagent. Qualitative analysis using the UV-Vis Spectrophotometry method. Results Research shows that the phytochemical screening test on keji beling leaf extract (Strobilanthes crispus BI.) is positive for containing flavonoids and tannins, indicated by a color change in the phytochemical screening test. Qualitative analysis results appear at a maximum wavelength  of 465 nm for flavonoids, and for tannin compounds at a maximum wavelength  of 765 nm.
Narrative Review: Optimation of Ethanol as a Solvent for Flavonoid Compounds in Papaya Leaf Extraction Davit Nugraha; Anna L Yusuf; Panji Wahlanto
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 2 (2023): Ad-Dawaa: Journal of Pharmacy (November 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i2.496

Abstract

Ethanol is widely used as a distiller of secondary metabolite compounds. Ethanol very well dissolves secondary metabolite compounds including flavonoids group compounds including for papaya (Carica papaya L.) leaf extraction. This review was conducted to examine solvent optimization that has been used in various original studies. The method of searching scientific journal article using PubMed and MDPI using keyword “extraction and ethanol and flavonoid and carica papaya leaf” with the inclusion criteria of 2018 – 2023 article, free full text and not review articles, the number of article obtained was 3 articles. The optimal concentration of ethanol as a flavonoid extract solven is 70 % ethanol at temperatures from 30 °C – 50°C with a time range of 10 – 48 hours of immersion.
Penyuluhan Tentang Pemanfaatan Sambiloto (Andrgraphis paniculata) Untuk Mencegah dan Mengobati Penyakit Hipertensi Siti Rahmah Kurnia Ramdan; Marlina Indriastuti; Anna L Yusuf; Davit Nugraha; Panji Wahlanto
Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 1 (2024): Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat (Januari-Juni 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/daipkm.v2i1.564

Abstract

Introduction: Hypertension is one of the factors causing cardiovascular disease and is the main cause of death in the world. Hypertension can be influenced by various factors, including genetic factors and an unhealthy lifestyle. Preventing and treating hypertension is very important in order to reduce risk factors for death. Prevention and treatment of hypertension with traditional medicine or herbal medicine is an alternative that is currently in great demand and attention because it has minimal side effects and is quite effective. Andrographis paniculata is a medicinal plant that has been widely studied and is effective in preventing and treating hypertension. The main content of this plant is andrographolidine which is a phytochemical substance which has many benefits, including antihypertension. Objective: The aim of this outreach activity is to provide understanding to the public about the use of bitter (Androghraphis paniculata) to prevent and treat hypertension. Method: Education to the public about the use of Androghraphis paniculata is carried out through the lecture method. The material presented is an explanation of hypertension, the benefits of bitter as a medicinal plant, the benefits of bitter in preventing and treating hypertension and how to process it on a household scale. Explanation of how to process bitter for treatment, namely using the infusion method. Giving pre-tests and post-tests to counseling participants is carried out to evaluate the level of community understanding. Result: By providing education about the use of bitter to prevent and treat hypertension, it can increase public knowledge about hypertension, the causal factors, as well as the benefits of bitter and how to use it as a medicinal plant. Knowledge before and after counseling increased by 36.65%. The community is very enthusiastic in following the outreach that we do. Conclusion: With the outreach, participants know more about hypertension and the use of bitter in preventing and treating hypertension and how to process it. Participants' knowledge increased by 36.65%.
AKTIVITAS ANTIBAKTERI AIR PERASAN BUAH PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus: ANTIBACTERIAL ACTIVITIES OF PEPAYA JUICE (Carica papaya L.) ON THE GROWTH OF Staphylococcus aureus BACTERIA Davit Nugraha; Anna L. Yusuf; Veri Nugraha; Panji Wahlanto; Marlina Indriastuti
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 4 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i4.470

Abstract

Bakteri Staphylococus aureus merupakan bakteri patogen dan dapat menyebabkan infeksi mulai dari infeksi kulit ringan sampai dengan infeksi sistemik. Sebagian besar pada awal mulanya Staphylococus aureus peka terhadap penisilin, namun setelah meluasnya penggunaan penisilin ditemukan 65% sampai 85% Staphylococus aureus menghasilkan beta laktamase sehingga menjadi resisten terhadap penisilin G.  Hal tersebut diatas mendorong pengobatan alternatif yang aman dan tidak menimbulkan resistensi untuk menanggulangi infeksi bakteri Staphylococus aureus.  Perasan buah pepaya sering terdengar penggunaan dimasyarakat untuk pengobatan jerawat secara turun temurun, ini dimungkinkan perasan buah pepaya mempunyai efek anti bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui kemampuan daya hambat air perasan buah papaya (Carica Papaya L) terhadap bakteri Staphylococcus aureus. Metode pengujian daya hambat pada air perasan buah papaya menggunakan metode difusi agar dengan konsentrasi 20%, 40%, 60% dan 80%. Air perasan buah pepaya pada penelitian ini mempunyai kemampuan daya hambat yang sedang terhadap pertumbuhan bakteri Staphylococcus aureus, serta konsentrasi yang paling efektif sebesar 60%.
Evaluation of Waiting Time for Recipe Services at Puskesmas Mangunjaya Based on Ministry of Health Regulation Permana, Kusyana Ade; Ismail, Rian; Wahlanto, Panji
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 1 (2024): Ad-Dawaa: Journal of Pharmacy (May 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i1.394

Abstract

Pharmaceutical services include resource management consisting of resources Humans, facilities, pharmaceutical preparations and health supplies as well as Administration and Pharmacy Services Clinical in efforts to achieve the stated goals. Prescription services are one of aspect clinical pharmacy services which include receiving prescriptions, assessment prescription administration, pharmaceutical suitability, drug compounding and packaging as well delivery of medication to patients. The aim of this research is to find out the waiting time for prescription services at the Mangunjaya Health Care Center (Puskesmas Mangunjaya) Pangandaran based on health minister regulations. The results of the research conducted from concoction recipes as many as 4 samples and no-concoction of 186 samples, waiting time Recipe and Non-concoction prescription services meet the standards, average Recipe Services concoction 14.86 minutes and average non -concoction recipe services 2.42 minutes. It can be concluded that prescription drugs are concoction and non The concoction at the Mangunjaya Health Center meets the minimum service standards in accordance with the Ministry of Health Regulation No.129/Menkes/SK/II/2008.
Antioxidant Activity Test of Ethanol Extract of Feather Plantain Fruit (Musa paradisiaca L) with the DPPH Method (1,1- Diphenyl-2-Picrylhydrazyl) Syahidatu, Dila; Firgiani, Gini; Ismail, Rian; Wahlanto, Panji
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 1 (2024): Ad-Dawaa: Journal of Pharmacy (May 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i1.414

Abstract

Antioxidants are compounds that can counteract or reduce the negative effects of free radicals. Antioxidants work by donating one electrons to compounds that are free radicals so that the activity of these compounds can be inhibited. This study aims to determine the activity and potential of antioxidants in the extract of banana feather fruit (Musa paradisiaca) which is taken from the village of Gunungcupu, Ciamis Regency. This feather plantain extract is obtained by maceration extraction using 70% ethanol. The antioxidant potential in this study was measured using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method by Uv-Vis spectrophotometry. The antioxidant activity of feather plantain extract and vitamin C were used as positive controls at concentrations of 10 ppm, 20 ppm, 30 ppm, 40 ppm, 50 ppm and 60 ppm. Absorbance measurements using Uv-Vis spectrophotometry at a maximum wavelength of 520 nm. The plantain feather extract has an IC50 value of 59.10 ppm. While vitamin C has an IC50 value of 73.20 ppm. Based on the classification of antioxidants strength, feather plantain extract and vitamin C have strong antioxidant activity.
The Influence of the Level of Public Knowledge on the Rationality of Self-Medicine for Diarrhea in Sukaratu Tasikmalaya Arman, Siti Alisa; Wahlanto, Panji
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 2 (2024): Ad-Dawaa: Journal of Pharmacy (November 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i2.733

Abstract

Self-medication is one of the choices of Indonesian people in treating their illnesses, one of which is treating diarrhea. Diarrhea is a symptom of abnormality in frequent bowel movements, with liquid stool consistency. The frequency of bowel movements is said to be abnormal if it is more than three times a day. The purpose of this study was to determine the relationship between the level of knowledge and the rationality of self-medication for diarrhea in Sukaratu Tasikmalaya. This study is an observational study, with a research design with a cross-sectional approach. The number of research samples was 43 people from Batu Bulu Village, Linggajati Village, Sukaratu District, Tasikmalaya Regency. The sampling technique was carried out using purposive sampling. Research data were obtained from questionnaires. Analysis of research data using the Pearson Correlation test, to determine the relationship between the level of community knowledge and the rationality of self-medication for diarrhea. The results showed that out of 43 respondents, 36 respondents had a level of knowledge in the good category, 2 respondents were sufficient and 5 respondents had poor knowledge. The distribution of rationality for self-medication for diarrhea showed that 24 respondents had the right rationality and 19 respondents had the wrong rationality.
OPTIMIZATION OF GELATIN CONCENTRATION IN TABLET WITH AFRICAN LEAF EXTRACT (Vernonia Amygdalina) Wahlanto, Panji; Yusuf, Anna L; Nugraha, Davit; Siti Rahmah KR; Dissya Alifia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1614

Abstract

African plants, especially the leaves, are a type of medicinal plant used by the community. This African leaf contains active lavonoids that can be used to measure blood glucose levels. Tablet preparations have the advantage that they are easy to consume, so in this study African leaves (Vernonia Amygdalina) were made into tablets. The ratios of the binder used were 4%, 5%, and 6%. After obtaining the evaluation results, data analysis was performed using the Kruskal–Wallis SPSS statistical test with a confidence level of 95%. The evaluation results showed that the three formulations only fulfilled the respective requirements, namely for the angle of repose test between 16.6° - 21.3°, the granule thickening test of all formulations is below <20% and meets the requirements, the weight uniformity test has an average of 191-192 mg meeting the predetermined requirements, namely not more than 3 times with an average of 7.35 -7.36 mm and a thickness of mean +  SD 0,47  the disintegration time test of all formulations stated that they met the requirements that had been determined that is not more than 15 minutes, the friability test only on formulation III which met the requirements to get a result of 0.54% in formulations I and II did not meet the specified requirements, the hardness test of all formulations did not meet the specified test requirements.  Keywords: African leaf extract, gelatin, tablets.
Co-Authors Anna L Yusuf Arman, Siti Alisa Asih, Aas Catia Athollah, Rifqi Nabil Ayu Safitri Chela Tiara Dewi Davit Nugraha desi karningsih Dissya Alifia Ditha Septya Utami Doni Setiawan Farah A Himah Fauzi, Rizky Mohammad Fawziah, Cindyvia Firgiani, Gini Harun, Nurhidayati Indriastuti, Marlina Ismail, Rian Lestari, Nina Indri Lisna Listiana Listyani, Tia M. Fadil Ramadhan Muhammad Jafar Shodiq Nia Kurniasih nia kurniasih Nova Zahra Novianty, Elisa Nugraha, Tuti Setia Permana, Kusyana Ade R, Susan Sintia Radhia Riski Rahmah KR, Siti Ramadhan, M. Fadil Ramdan, Siti Rahmah Kurnia Rian Ismail Siti Rahmah KR Siti Rahmah Kurnia Ramdan Susan Sintia Ramadhani Syahidatu, Dila Utami, Ditha Septya Veri Nugraha Yunia Purwati Yusuf, Anna