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Optimization of Carbopol 940 Coriander Leaf Extract Gel (Coriandrum sativum L): Analysis of Physical Properties : EFFECT OF CARBOPOL 940 CONCENTRATION ON PHYSICAL PROPERTIES OF CORIANDER LEAF EXTRACT GEL (CORIANDRUM SATIVUM L.) Nugraha, Davit; Rahmah KR, Siti; Wahlanto, Panji; Fawziah, Cindyvia; Yusuf, Anna
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1883

Topical gels are widely used because they are convenient to apply, easily absorbed, and have good stability. Carbopol 940 is one of the thickening agents often used in gel formulations because it can produce high viscosity at low concentrations and is compatible with various active ingredients. In gel formulation, the selection of Carbopol 940 concentration is very important to determine physical properties such as viscosity, pH, spreadability, and stability. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. This study aims to examine the effect of Carbopol 940 concentration on the physical properties of gel containing coriander leaf extract by experimental method with variation of Carbopol 940 concentration in coriander leaf extract gel formulation. The physical properties of the gel, such as viscosity, pH, spreadability, and stability, were tested using physicochemical parameters to evaluate the effect of Carbopol concentration on the quality of the preparation. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. The results showed that the concentration of Carbopol 940 significantly affected the physical properties of the gel, including viscosity, spreadability, and pH. The conclusion shows that the optimal formulation of Carbopol 940 can produce coriander leaf extract gel with physical properties that meet the requirements of topical drugs. Keywords: Gel, Coriander Leaf Extract, Formulation, Physical Properties Test

FORMULASI KRIM WAJAH EKSTRAK PELEPAH POHON AREN (Arenga pinnata Merr.) SEBAGAI ANTI ACNE Fauzi, Rizky Mohammad; Nugraha, Davit; Wahlanto, Panji
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p26-31

Aren (Arenga pinnata Merr.) is a biological resource believed to have antioxidant abilities and is easily found throughout Indonesia. It is widely used by the populace, for example in midrib flour as a traditional medicine to relieve itching and scars on the skin. The purpose of this study was to determine whether the palm leaf extract (Arenga pinnata Merr.) could be formulated into cream preparations and was of good quality. The research method used is experimental by formulating the extract into three formulations, namely the extract concentration of 1%, 3%, 5%. Data analysis was performed using qualitative analysis including organoleptic test, homogeneity test, and quantitative analysis including pH test, dispersion test, adhesion test, viscosity and using one-way ANOVA statistics. The results of the analysis showed that there was no significant difference in the concentration of palm midrib cream in pH with a sig value of 0.542 (sig. > 0.05), a dispersion of 0.504 (sig. > 0.05) and a Adhesion of 0.717 (sig. > 0.05) gave > 0.05) and the viscosity meets the standard of good cream viscosity which is between (2000 - 50000 cps). Data analysis of the results showed that the three variations of extracts could be formulated into cream preparations and had quality standards for cream preparations that met the requirements, there was no effect of variations in the concentration of arene (Arenga pinnata Merr.) on the physical quality of cream preparations. The best wording is found in F2 (3%). Further research is expected to modify the formula for preservatives and fragrance additives, create new dosage forms such as lotions.

Study of Taurine Content in Energy Drink Powders: UV-Vis Spectrophotometric Method Ramdan, Siti Rahmah Kurnia; Athollah, Rifqi Nabil; Yusuf, Anna L; Nugraha, Davit; Wahlanto, Panji
INDOGENIUS Vol 4 No 2 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i2.593

Background and Objective: Energy drinks are commonly consumed as a fast and affordable solution to fatigue, especially among adolescents and young adults. However, public knowledge about their appropriate use and the health risks of excessive intake remains limited. Taurine (2-aminoethanesulfonic acid), a conditionally essential amino acid found in many energy drinks, contributes to several physiological functions. Excessive intake of taurine may adversely affect kidney function. Method: The method of this study using UV-Vis spectrophotometry. A 0.1% ninhydrin solution was used for qualitative testing, while UV-Vis spectrophotometry was employed for quantitative measurement. Proteins were precipitated using Carrez I and Carrez II reagents before analysis. Results: A purplish-blue color change in the qualitative test confirmed the presence of taurine. Quantitative analysis revealed taurine concentrations of 0.025% and 0.012% in the two samples. Conclusion: The results validate UV-Vis spectrophotometry as a practical and dependable technique for analyzing taurine, highlighting the importance of educating the public on the associated health risks of excessive consumption.

Analysis of Antihypertensive Drug Prescription Patterns in Outpatients at the DTP Cihaurbeuti Health Center Health Service Unit Nugraha, Tuti Setia; Wahlanto, Panji; Novianty, Elisa
Ad-Dawaa : Journal of Pharmacy Vol. 3 No. 1 (2025): Ad-Dawaa: Journal of Pharmacy (May 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v3i1.870

Hypertension is a condition in which a person experiences an increase in blood pressure above normal, specifically systolic blood pressure 140 mmHg and/or diastolic blood pressure 90 mmHg. Hypertension is a silent killer, known as a prevalent cardiovascular disease. Hypertension is one of the main factors causing the number one death in the world. The aim of this study was to analyze the pattern of prescribing antihypertensive drugs in UPTD Health of DTP Cihaurbeuti Health Center in the period January-March 2020. The aim of this study was to analyze the pattern of prescribing antihypertensive drugs in UPTD Health of DTP Cihaurbeuti Health Center in the period January-March 2020. With the preparation stage method, study stage, data processing, and analysis. Based on the results obtained in the study, namely the Prescription of antihypertensive drugs at the UPTD DTP Cihaurbeuti Health Center for the period January-March 2020, most of the patients were female (78.37%), aged 56-65 years (45.51%), and suffered from grade 2 hypertension (52.24%). ACEI class drugs (captopril) as much as 1.61%, CCB class (amlodipine) as much as 95.97% and diuretic class (furosemide) as much as 0.85%. Based on the drug class criteria of 100%. Drug type criteria of 100%.

The Potency of Moringa Leaf Extract (Moringa oleifera L.) In a Facial Treatment Mist Formulation Over Acne and Bacteria Indriastuti, Marlina; Listyani, Tia; Wahlanto, Panji; Setiawan, Doni; Harun, Nurhidayati; Kurniasih, Nia; Riski, Radhia
JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS Vol. 12 No. 2 (2025): Jurnal Kesehatan (Oktober 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/jurkes.v12i2.864

Background: It is often known that moringa leaves (Moringa oleifera L.) are a natural substance with many advantages, especially for their antibacterial qualities that prevent the growth of bacteria. Objectives: The main objective of this study was to evaluate the efficacy of particular face mist preparation made from Moringa leaf extract in inhibiting the growth of Propionibacterium acnes, the bacteria that causes facial acne. Methods: A facial mist containing moringa extract was created, and its antibacterial qualities were assessed using the Kirby-Bauer technique in conjuction with the agar duffision method. Results: The face mist preparation effectively satiated the homogeneity, pH, viscosity, and spray pattern physical assesment criteria in the organoleptic test. Conclusions: Strong anti-acne and antibacterial properties were present in the face mist preparation made from moringa leaf extract, especially at a concentration of 45% that sucesfully stopped the growth of all test.

Isolasi dan Identifikasi Kurkumin Ekstrak Etanol Temulawak (Curcuma xanthorriza Roxb.) dengan Metode Kromatografi Kolom Ramdan, Siti Rahmah Kurnia; Asih, Aas Catia; Yusuf, Anna L; Nugraha, Davit; Indriastuti, Marlina; Wahlanto, Panji
Pharmacogenius Journal Vol 3 No 3 (2024): Pharmacy Genius
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/pharmgen.v3i3.427

Pendahuluan: Temulawak telah banyak digunakan oleh masyarakat dalam pengobatan tradisional dengan berbagai manfaat. Rimpang temulawak mengandung kurkumin, serat, pati, kalium oksalat, minyak atsiri, flavonoid dan zat-zat tersebut berfungsi sebagai antimikroba, mencegah penggumpalan darah, immunostimulan, anti peradangan, melancarkan metabolisme dan fungsi organ tubuh. Tujuan: Tujuan dari penelitian ini untuk melakukan isolasi kurkumin dari ekstrak etanol 95% temulawak dengan menggunakan kromatografi kolom, kemudian diidentifikasi spektrofotometri UV-Vis pada panjang gelombang 400-800 nm. Metode: Metode penelitian yaitu isolasi kurkumin dengan kromatografi kolom terhadap ekstrak etanol 95% temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1), selanjutnya dilakukan identifikasi dengan spektrofotometri UV-Vis pada panjang gelombang 400nm-800nm. Hasil: Hasil isolasi senyawa kurkumin dari ekstrak temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1) diperoleh dengan menggunakan kromatografi kolom berupa cairan berwarna kuning pekat, kemudian identifikasi dengan spektrofotometri UV Vis dan diperoleh nilai absorbansi tertinggi pada panjang gelombang maksimum 425 nm. Kesimpulan: Dari data tersebut dapat disimpulkan bahwa kurkumin dapat diisolasi dari ekstrak temulawak dengan metode kromatografi kolom dan diidentifikasi dengan Spektrofotometri Uv Vis.

The Potency of Moringa Leaf Extract (Moringa oleifera L.) In a Facial Treatment Mist Formulation Over Acne and Bacteria Indriastuti, Marlina; Listyani, Tia; Wahlanto, Panji; Setiawan, Doni; Harun, Nurhidayati; Kurniasih, Nia; Riski, Radhia
JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS Vol. 12 No. 2 (2025): Jurnal Kesehatan (Oktober 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/jurkes.v12i2.864

Background: It is often known that moringa leaves (Moringa oleifera L.) are a natural substance with many advantages, especially for their antibacterial qualities that prevent the growth of bacteria. Objectives: The main objective of this study was to evaluate the efficacy of particular face mist preparation made from Moringa leaf extract in inhibiting the growth of Propionibacterium acnes, the bacteria that causes facial acne. Methods: A facial mist containing moringa extract was created, and its antibacterial qualities were assessed using the Kirby-Bauer technique in conjuction with the agar duffision method. Results: The face mist preparation effectively satiated the homogeneity, pH, viscosity, and spray pattern physical assesment criteria in the organoleptic test. Conclusions: Strong anti-acne and antibacterial properties were present in the face mist preparation made from moringa leaf extract, especially at a concentration of 45% that sucesfully stopped the growth of all test.

Relationship Between Personal Hygiene Behavior Bathing Behavior and Sleeping Behavior with the Incidence of Scabies Among Students at the Manhajul Ulum Islamic Boarding School Ciamis Regency Nurapandi, Adi; Nurlela, Intan Putri; Rahman, Irpan Ali; Asmarani, Sri Utami; MJW, Endrian; Wahlanto, Panji; Noviati, Elis; Lestari, Lusi
JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS Vol. 12 No. 2 (2025): Jurnal Kesehatan (Oktober 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/jurkes.v12i2.964

Scabies is a skin disease that is still common in Indonesia and remains a public health problem. According to the World Health Organization (WHO) the incidence of scabies in 2014 was 130 million people worldwide. According to data from the Ministry of Health of the Republic of Indonesia, the prevalence of scabies in 2017 is 6% of the total population of Indonesia, while scabies is still ranked 9 of the 10 largest diseases in West Java Province with a total of 38,854 cases in 2011. Based on outpatient reports of the Rajadesa Health Center the incidence of scabies in months In October 2020 there were around 39 cases, while in the Manhajul Ulum Islamic Boarding School, Ciamis Regency, data was obtained that as many as 60 students suffered from scabies in October 2020. To determine the relationship between personal hygiene behavior, bathing behavior and sleeping behavior with the incidence of scabies among students at the Manhajul Ulum Islamic Boarding School, Ciamis Regency. Quantitative research methods using a correlation design and retrospective research design. Total population of 90 students who suffer from scabies and who do not suffer from scabies in the Manhajul Ulum Islamic Boarding School, Ciamis Regency, and the sampling used the total sampling method, namely the entire population was used as a sample of 90 respondents. The results showed that there were 60 people (66.7%) who suffered from scabies, 34 people (37.8%) who suffered from scabies, 34 people (37.8%) who were in poor category and 36 people (40.0%) suffered from scabies. with the less category. The results of statistical tests showed that there was a relationship between personal hygiene behavior in bathing behavior and the incidence of scabies (p = 0.023 <0.05) and there was a relationship between personal hygiene behavior in sleep behavior and the incidence of scabies (p = 0.011 <0.05) at the Manhajul Ulum Islamic Boarding School. Ciamis Regency. The conclusion of this study states that there is a significant relationship between personal hygiene behavior, bathing behavior and sleep behavior with the incidence of scabies among students at the Manhajul Ulum Islamic Boarding School, Ciamis Regency.

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