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All Journal Jurnal Wiyata : Penelitian Sains dan Kesehatan Meditory : The Journal of Medical Laboratory JFL : Jurnal Farmasi Lampung Jurnal Kesehatan: Jurnal Ilmu- Ilmu Keperawatan, Kebidanan, Farmasi dan Analis Kesehatan Jurnal Farmasi dan Sains Indonesia (JFSI) Medical Sains : Jurnal Ilmiah Kefarmasian INDOGENIUS Pharmacy Genius Ad-dawaa: Journal Of Pharmacy Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian
panji wahlanto
STIKes Muhammadiyah Ciamis
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Optimization of Carbopol 940 Coriander Leaf Extract Gel (Coriandrum sativum L): Analysis of Physical Properties : EFFECT OF CARBOPOL 940 CONCENTRATION ON PHYSICAL PROPERTIES OF CORIANDER LEAF EXTRACT GEL (CORIANDRUM SATIVUM L.) Nugraha, Davit; Rahmah KR, Siti; Wahlanto, Panji; Fawziah, Cindyvia; Yusuf, Anna
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1883

Abstract

Topical gels are widely used because they are convenient to apply, easily absorbed, and have good stability. Carbopol 940 is one of the thickening agents often used in gel formulations because it can produce high viscosity at low concentrations and is compatible with various active ingredients. In gel formulation, the selection of Carbopol 940 concentration is very important to determine physical properties such as viscosity, pH, spreadability, and stability. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. This study aims to examine the effect of Carbopol 940 concentration on the physical properties of gel containing coriander leaf extract by experimental method with variation of Carbopol 940 concentration in coriander leaf extract gel formulation. The physical properties of the gel, such as viscosity, pH, spreadability, and stability, were tested using physicochemical parameters to evaluate the effect of Carbopol concentration on the quality of the preparation. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. The results showed that the concentration of Carbopol 940 significantly affected the physical properties of the gel, including viscosity, spreadability, and pH. The conclusion shows that the optimal formulation of Carbopol 940 can produce coriander leaf extract gel with physical properties that meet the requirements of topical drugs. Keywords:  Gel, Coriander Leaf Extract, Formulation, Physical Properties Test
FORMULASI KRIM WAJAH EKSTRAK PELEPAH POHON AREN (Arenga pinnata Merr.) SEBAGAI ANTI ACNE Fauzi, Rizky Mohammad; Nugraha, Davit; Wahlanto, Panji
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p26-31

Abstract

Aren (Arenga pinnata Merr.) is a biological resource believed to have antioxidant abilities and is easily found throughout Indonesia. It is widely used by the populace, for example in midrib flour as a traditional medicine to relieve itching and scars on the skin. The purpose of this study was to determine whether the palm leaf extract (Arenga pinnata Merr.) could be formulated into cream preparations and was of good quality. The research method used is experimental by formulating the extract into three formulations, namely the extract concentration of 1%, 3%, 5%. Data analysis was performed using qualitative analysis including organoleptic test, homogeneity test, and quantitative analysis including pH test, dispersion test, adhesion test, viscosity and using one-way ANOVA statistics. The results of the analysis showed that there was no significant difference in the concentration of palm midrib cream in pH with a sig value of 0.542 (sig. > 0.05), a dispersion of 0.504 (sig. > 0.05) and a Adhesion of 0.717 (sig. > 0.05) gave > 0.05) and the viscosity meets the standard of good cream viscosity which is between (2000 - 50000 cps). Data analysis of the results showed that the three variations of extracts could be formulated into cream preparations and had quality standards for cream preparations that met the requirements, there was no effect of variations in the concentration of arene (Arenga pinnata Merr.) on the physical quality of cream preparations. The best wording is found in F2 (3%). Further research is expected to modify the formula for preservatives and fragrance additives, create new dosage forms such as lotions.
Study of Taurine Content in Energy Drink Powders: UV-Vis Spectrophotometric Method Ramdan, Siti Rahmah Kurnia; Athollah, Rifqi Nabil; Yusuf, Anna L; Nugraha, Davit; Wahlanto, Panji
INDOGENIUS Vol 4 No 2 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i2.593

Abstract

Background and Objective: Energy drinks are commonly consumed as a fast and affordable solution to fatigue, especially among adolescents and young adults. However, public knowledge about their appropriate use and the health risks of excessive intake remains limited. Taurine (2-aminoethanesulfonic acid), a conditionally essential amino acid found in many energy drinks, contributes to several physiological functions. Excessive intake of taurine may adversely affect kidney function. Method: The method of this study using UV-Vis spectrophotometry. A 0.1% ninhydrin solution was used for qualitative testing, while UV-Vis spectrophotometry was employed for quantitative measurement. Proteins were precipitated using Carrez I and Carrez II reagents before analysis. Results: A purplish-blue color change in the qualitative test confirmed the presence of taurine. Quantitative analysis revealed taurine concentrations of 0.025% and 0.012% in the two samples.  Conclusion: The results validate UV-Vis spectrophotometry as a practical and dependable technique for analyzing taurine, highlighting the importance of educating the public on the associated health risks of excessive consumption.
Analysis of Antihypertensive Drug Prescription Patterns in Outpatients at the DTP Cihaurbeuti Health Center Health Service Unit Nugraha, Tuti Setia; Wahlanto, Panji; Novianty, Elisa
Ad-Dawaa : Journal of Pharmacy Vol. 3 No. 1 (2025): Ad-Dawaa: Journal of Pharmacy (May 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v3i1.870

Abstract

Hypertension is a condition in which a person experiences an increase in blood pressure above normal, specifically systolic blood pressure  140 mmHg and/or diastolic blood pressure  90 mmHg. Hypertension is a silent killer, known as a prevalent cardiovascular disease. Hypertension is one of the main factors causing the number one death in the world. The aim of this study was to analyze the pattern of prescribing antihypertensive drugs in UPTD Health of DTP Cihaurbeuti Health Center in the period January-March 2020. The aim of this study was to analyze the pattern of prescribing antihypertensive drugs in UPTD Health of DTP Cihaurbeuti Health Center in the period January-March 2020. With the preparation stage method, study stage, data processing, and analysis. Based on the results obtained in the study, namely the Prescription of antihypertensive drugs at the UPTD DTP Cihaurbeuti Health Center for the period January-March 2020, most of the patients were female (78.37%), aged 56-65 years (45.51%), and suffered from grade 2 hypertension (52.24%). ACEI class drugs (captopril) as much as 1.61%, CCB class (amlodipine) as much as 95.97% and diuretic class (furosemide) as much as 0.85%. Based on the drug class criteria of 100%. Drug type criteria of 100%.
The Potency of Moringa Leaf Extract (Moringa oleifera L.) In a Facial Treatment Mist Formulation Over Acne and Bacteria Indriastuti, Marlina; Listyani, Tia; Wahlanto, Panji; Setiawan, Doni; Harun, Nurhidayati; Kurniasih, Nia; Riski, Radhia
JURNAL KESEHATAN STIKes MUHAMMADIYAH CIAMIS Vol. 12 No. 2 (2025): Jurnal Kesehatan (Oktober 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/jurkes.v12i2.864

Abstract

Background: It is often known that moringa leaves (Moringa oleifera L.) are a natural substance with many advantages, especially for their antibacterial qualities that prevent the growth of bacteria. Objectives: The main objective of this study was to evaluate the efficacy of particular face mist preparation made from Moringa leaf extract in inhibiting the growth of Propionibacterium acnes, the bacteria that causes facial acne. Methods: A facial mist containing moringa extract was created, and its antibacterial qualities were assessed using the Kirby-Bauer technique in conjuction with the agar duffision method. Results: The face mist preparation effectively satiated the homogeneity, pH, viscosity, and spray pattern physical assesment criteria in the organoleptic test. Conclusions: Strong anti-acne and antibacterial properties were present in the face mist preparation made from moringa leaf extract, especially at a concentration of 45% that sucesfully stopped the growth of all test.
Isolasi dan Identifikasi Kurkumin Ekstrak Etanol Temulawak (Curcuma xanthorriza Roxb.) dengan Metode Kromatografi Kolom Ramdan, Siti Rahmah Kurnia; Asih, Aas Catia; Yusuf, Anna L; Nugraha, Davit; Indriastuti, Marlina; Wahlanto, Panji
Pharmacogenius Journal Vol 3 No 3 (2024): Pharmacy Genius
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/pharmgen.v3i3.427

Abstract

Pendahuluan: Temulawak telah banyak digunakan oleh masyarakat dalam pengobatan tradisional dengan berbagai manfaat. Rimpang temulawak mengandung kurkumin, serat, pati, kalium oksalat, minyak atsiri, flavonoid dan zat-zat tersebut berfungsi sebagai antimikroba, mencegah penggumpalan darah, immunostimulan, anti peradangan, melancarkan metabolisme dan fungsi organ tubuh. Tujuan: Tujuan dari penelitian ini untuk melakukan isolasi kurkumin dari ekstrak etanol 95% temulawak dengan menggunakan kromatografi kolom, kemudian diidentifikasi spektrofotometri UV-Vis pada panjang gelombang 400-800 nm. Metode: Metode penelitian yaitu isolasi kurkumin dengan kromatografi kolom terhadap ekstrak etanol 95% temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1), selanjutnya dilakukan identifikasi dengan spektrofotometri UV-Vis pada panjang gelombang 400nm-800nm. Hasil: Hasil isolasi senyawa kurkumin dari ekstrak temulawak dengan eluen kloroform:etanol:asam asetat glasial (94:5:1) diperoleh dengan menggunakan kromatografi kolom berupa cairan berwarna kuning pekat, kemudian identifikasi dengan spektrofotometri UV Vis dan diperoleh nilai absorbansi tertinggi pada panjang gelombang maksimum 425 nm. Kesimpulan: Dari data tersebut dapat disimpulkan bahwa kurkumin dapat diisolasi dari ekstrak temulawak dengan metode kromatografi kolom dan diidentifikasi dengan Spektrofotometri Uv Vis.
Co-Authors Anna L Yusuf Arman, Siti Alisa Asih, Aas Catia Athollah, Rifqi Nabil Ayu Safitri Chela Tiara Dewi Davit Nugraha desi karningsih Dissya Alifia Ditha Septya Utami Doni Setiawan Farah A Himah Fauzi, Rizky Mohammad Fawziah, Cindyvia Firgiani, Gini Harun, Nurhidayati Indriastuti, Marlina Ismail, Rian Lestari, Nina Indri Lisna Listiana Listyani, Tia M. Fadil Ramadhan Muhammad Jafar Shodiq Nia Kurniasih nia kurniasih Nova Zahra Novianty, Elisa Nugraha, Tuti Setia Permana, Kusyana Ade R, Susan Sintia Radhia Riski Rahmah KR, Siti Ramadhan, M. Fadil Ramdan, Siti Rahmah Kurnia Rian Ismail Siti Rahmah KR Siti Rahmah Kurnia Ramdan Susan Sintia Ramadhani Syahidatu, Dila Utami, Ditha Septya Veri Nugraha Yunia Purwati Yusuf, Anna