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All Journal Jurnal Abdimas Ilmiah Citra Bakti (JAICB) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia
Putri, Athika Darumas
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Physics Social Sciences

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THE IN VITRO AND IN VIVO EFFECTS OF Persea Americana ETHANOL EXTRACT AS AN ANTIHYPERTENSIVE AND ANTIOXIDANT IN PREDNISONE-INDUCED RATS Elisa, Novi; Dian Advistasari, Yustisia; Sari, Wulan Kartika; Pratiwi, Mustika Endah; Tobi, Claudius Hendraman Boli; Murti, Bayu Tri; Putri, Athika Darumas
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.6583

Abstract

Hypertension impacts the quantity of free radicals within the body. This study aimed to investigate the effect of antihypertension based on free radical levels in the predni-sone-induced rats, focusing on evaluating specific anti-hypertensive fraction of avoca-do leaves. The study's methods conducting GC-MS, anti-hypertensive, and assessing malondialdehyde levels and catalase enzyme. Systolic blood pressure measurements indicated that the positive control (131 ± 3 mmHg) and ethyl acetate fraction (136 ± 4 mmHg) were statistically similar, significantly different from the negative control group. Diastolic blood pressure measurements showed a blood pressure decreasing in posi-tive control (105 ± 7) that similar statistically with ethyl acetate fraction (104 ± 6), and significantly difference with negative control group. Malondialdehyde levels were nota-bly elevated in both the positive control (37.79 ± 5.47) and ethyl acetate fraction (38.01 ± 5.47) compared to the negative control (-9.07 ± 10.10), indicating increased free rad-ical. Catalase activity demonstrated significant differences, with the positive control (44.06 ± 5.44) and ethyl acetate fraction (44.05 ± 5.45) showing similar levels, both substantially higher than the negative control (13.90 ± 21.50). In summary, this study indentificates several flavonoid compounds that promising anti-hypertension effect from ethyl acetate fraction of avocado leaves extract.
EDUKASI DAN PELATIHAN BISKUIT MPASI BERBASIS KACANG MERAH UNTUK MENDUKUNG PENCEGAHAN STUNTING DI DESA DLIMOYO, TEMANGGUNG, JAWA TENGAH Putri, Athika Darumas; Anggoro, Aloysius Barry; Indriyanti, Erwin; Syukur, Mighfar; Setyowatiningsih, Endang; Pancasona, Putri Yuliana; Nafasya, Meyra Wahyu
Jurnal Abdimas Ilmiah Citra Bakti Vol. 6 No. 3 (2025)
Publisher : STKIP Citra Bakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38048/jailcb.v6i3.5470

Abstract

Permasalahan utama di Desa Dlimoyo, Kecamatan Ngadirejo, Kabupaten Temanggung, adalah rendahnya pemanfaatan kacang merah sebagai bahan pangan bergizi serta kurangnya pengetahuan masyarakat mengenai pencegahan stunting melalui pemberian Makanan Pendamping ASI (MPASI) yang tepat. Kondisi ini berkontribusi terhadap tingginya prevalensi stunting di desa tersebut. Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan gizi masyarakat sekaligus keterampilan praktis dalam mengolah kacang merah menjadi biskuit MPASI bergizi. Mitra kegiatan adalah kelompok ibu PKK dan kader posyandu Desa Dlimoyo sebanyak 40 peserta yang memiliki peran strategis dalam pemberian MPASI di tingkat rumah tangga. Metode pelaksanaan meliputi survei awal, ceramah edukatif mengenai stunting dan gizi kacang merah, demonstrasi pembuatan biskuit MPASI, diskusi interaktif, serta evaluasi melalui pre-test dan post-test untuk mengukur peningkatan pengetahuan dan keterampilan. Hasil kegiatan menunjukkan peningkatan pengetahuan peserta sebesar 80%, keterampilan dalam pembuatan biskuit MPASI sesuai standar keamanan pangan, dan munculnya inisiatif untuk mengembangkan produk sebagai usaha rumah tangga berbasis pangan lokal. Kesimpulan dari kegiatan ini adalah bahwa edukasi gizi berbasis potensi lokal yang dipadukan dengan praktik langsung efektif meningkatkan literasi gizi, keterampilan pengolahan pangan, serta mendukung pencegahan stunting secara berkelanjutan di masyarakat.
THE IN VITRO AND IN VIVO EFFECTS OF Persea Americana ETHANOL EXTRACT AS AN ANTIHYPERTENSIVE AND ANTIOXIDANT IN PREDNISONE-INDUCED RATS Elisa, Novi; Dian Advistasari, Yustisia; Sari, Wulan Kartika; Pratiwi, Mustika Endah; Tobi, Claudius Hendraman Boli; Murti, Bayu Tri; Putri, Athika Darumas
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.6583

Abstract

Hypertension impacts the quantity of free radicals within the body. This study aimed to investigate the effect of antihypertension based on free radical levels in the predni-sone-induced rats, focusing on evaluating specific anti-hypertensive fraction of avoca-do leaves. The study's methods conducting GC-MS, anti-hypertensive, and assessing malondialdehyde levels and catalase enzyme. Systolic blood pressure measurements indicated that the positive control (131 ± 3 mmHg) and ethyl acetate fraction (136 ± 4 mmHg) were statistically similar, significantly different from the negative control group. Diastolic blood pressure measurements showed a blood pressure decreasing in posi-tive control (105 ± 7) that similar statistically with ethyl acetate fraction (104 ± 6), and significantly difference with negative control group. Malondialdehyde levels were nota-bly elevated in both the positive control (37.79 ± 5.47) and ethyl acetate fraction (38.01 ± 5.47) compared to the negative control (-9.07 ± 10.10), indicating increased free rad-ical. Catalase activity demonstrated significant differences, with the positive control (44.06 ± 5.44) and ethyl acetate fraction (44.05 ± 5.45) showing similar levels, both substantially higher than the negative control (13.90 ± 21.50). In summary, this study indentificates several flavonoid compounds that promising anti-hypertension effect from ethyl acetate fraction of avocado leaves extract.
Co-Authors Anggoro, Aloysius Barry Claudius Hendraman B. Tobi Dian Advistasari, Yustisia Elisa, Novi Indriyanti, Erwin Murti, Bayu Tri Mustika Endah Pratiwi Nafasya, Meyra Wahyu Pancasona, Putri Yuliana Sari, Wulan Kartika Setyowatiningsih, Endang Syukur, Mighfar Wulan Kartika Sari