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All Journal HAYATI Journal of Biosciences MEDISAINS Majalah Obat Tradisional Science and Technology Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Pendidikan Kimia (JPKim) Jurnal Aisyah : Jurnal Ilmu Kesehatan COMMUNITY : Jurnal Pengabdian Kepada Masyarakat JIFI (Jurnal Ilmiah Farmasi Imelda) Nurse and Holistic Care JKKI : Jurnal Kedokteran dan Kesehatan Indonesia International Journal of Health and Pharmaceutical (IJHP) Jurnal Natural
IKHTIARI, REFI
Department Of Biomedical Sciences, Faculty Of Medicine, Universitas Prima Indonesia, Medan, 20118, Indonesia
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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THE ROLE OF SOCIAL SUPPORT AND EDUCATION LEVEL IN ADHERENCE TO ANTI-RETROVIRAL (ARV) DRUGS IN HIV/AIDS PATIENTS: NARATIVE REVIEW Girsang, Jakasmir; Nababan, Tiarnida; Ikhtiari, Refi
Nurse and Holistic Care Vol. 5 No. 2 (2025): Nurse and Holistic Care
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/nhc.v5i2.7601

Abstract

Background: Adherence to antiretroviral (ARV) therapy is essential for effective HIV/AIDS management. Social support and patients’ education levels have been shown to influence treatment adherence. Objective: To review the role of social support and education in adherence to ARV medication among people living with HIV/AIDS (PLWHA). Methods: This study is a narrative literature review. Articles were retrieved from Google Scholar using predefined inclusion and exclusion criteria. The quality of the selected studies was assessed using the JBI Critical Appraisal Checklist, and findings were synthesized thematically. Results: Ten articles met the inclusion criteria (n = 10). Most studies reported that family support and higher education levels were positively associated with better adherence to ARV therapy. Conclusion: Social support and education are key determinants of ARV adherence. Interventions that emphasize patient education and family involvement are recommended to improve treatment outcomes in PLWHA.
Linking MDA Levels and Blood Glucose in Streptozotocin-Induced Rat Diabetes: Implications for Diabetic Complications and Therapeutic Strategies Angie, Evelyn; Girsang, Ermi; Ikhtiari, Refi
Jurnal Penelitian Pendidikan IPA Vol 10 No 6 (2024): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i6.7220

Abstract

Diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels resulting from insulin deficiency or resistance. Streptozotocin, a potent diabetogenic agent, is commonly employed to induce experimental diabetes by selectively damaging pancreatic beta cells, resulting in insulin deficiency and hyperglycemia. Elevated Malondialdehyde (MDA) levels, indicative of oxidative stress and lipid peroxidation, are closely linked to diabetic complications. This study aimed to investigate the association between MDA levels and blood glucose in Streptozotocin-induced rat diabetes, shedding light on potential therapeutic strategies. Spectrophotometric analysis was utilized to quantify MDA levels in rat tissues, providing insights into the extent of oxidative damage. The results revealed a significant correlation between MDA levels and blood glucose, highlighting the role of oxidative stress in diabetic pathogenesis. These findings underscore the importance of targeting oxidative stress in diabetes management to prevent complications. In conclusion, the study emphasizes the relevance of monitoring MDA levels as a biomarker for assessing oxidative stress in diabetic conditions and guiding therapeutic interventions.
Acute Toxicity Test of Lancing Leaf Extract (Solanum Mauritianum Scop.) as Well as Determination of Ld50 Values and Histopathology in Male Mice (Wistar Rat) Afifah Ikhwan; Erny Tandanu; Ali Napiah Nasution; Refi Ikhtiari
Jurnal Penelitian Pendidikan IPA Vol 11 No 6 (2025): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i6.10776

Abstract

The purpose of this study is to find out about the acute toxicity test and analysis of its activity on lancing leaves. This research method is an experimental method including sampling and sample processing, extract making, acute toxicity tests, research on toxic symptoms in animals, organ harvesting, organ weighing, organ histopathology examination and data analysis with Statistical Program Service Solution (SPSS).  The research was conducted at the Integrated Development and Research Laboratory of Andalas University from September 2024 to December 2024. The tools used in this study are Rotary evaporator (Buchi R-210 Rotavapor), separation funnel, oven (Memmert), furnace, analytical scale (SF-400), decigator, mortar and pestle, porcelain cruce, Moisture Analyzer, Hot plate, Uv-Visible lamp (Camag), dark bottle, funnel, infusion bottle (500 ml and 100 ml), glass beaker (Pyrex), drip plate, rack and test tube, measuring cup (Pyrex), measuring flask,  spatels, stirring rods, droppers, ointment pots, object glass, KLT chambers, capillary pipes, syringes, sondes, animal cages, animal feeding and drinking places. The animals that will be used in this study are healthy male white rats aged 2-3 months with a body weight of 200-300 g and have never been used for experiments as many as 25 animalsAn LD50 value was obtained with a mild toxic value (>2000 mg/KgBB – 5000 mg/KgBB) against the acute toxicity test of lancing leaf extract (Solanum Mauritianum Scop.) in male rats. There was no significant difference between groups (p>0.05) in the body and BOR of male rats compared to the control group after administration of lancing leaf extract (Solanum Mauritianum Scop.).
AKSI TIGA PILAR: LOGISTIK CEPAT, GIZI TEPAT, DAN PEMBERIAN LAYANAN TRAUMA UNTUK TANGGAP BENCANA DI LANGKAT (SUMATERA UTARA) Purba, Windania; Ikhtiari, Refi; Ginting, Rapael
COMMUNITY : Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 1 (2026)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/community.v6i1.9416

Abstract

The flood disaster that struck the Tanjung Pura area of ​​Langkat Regency, North Sumatra, had a significant impact on the social, economic, health, and psychological well-being of the community. Limited access to basic necessities, decreased nutritional quality, and the emergence of psychological trauma, particularly among vulnerable groups such as children, the elderly, and pregnant women, are key issues requiring rapid and integrated response. This community service activity aims to provide a disaster response through a Three-Pillar Action approach: Rapid Logistics, Appropriate Nutrition, and Trauma Services. The implementation method was participatory, encompassing preparation and coordination with local partners, core activities such as the distribution of logistical assistance and nutritious food, and trauma healing services. The program concluded with monitoring and evaluation. The aid distributed included basic food packages, hygiene kits, clothing, and psychosocial support for the affected community. Results from the activity indicate that this program was able to meet the community's basic needs quickly and effectively, improve nutritional intake, especially for vulnerable groups, and help reduce stress and trauma caused by the disaster. Thus, the Three Pillars Action approach has proven effective as a holistic and sustainable disaster response model in supporting the physical and psychological recovery of affected communities. ABSTRAK Bencana banjir yang melanda wilayah Tanjung Pura, Kabupaten Langkat, Sumatera Utara, menimbulkan dampak signifikan terhadap kehidupan sosial, ekonomi, kesehatan, dan kondisi psikologis masyarakat. Terbatasnya akses terhadap kebutuhan dasar, menurunnya kualitas asupan gizi, serta munculnya trauma psikologis, khususnya pada kelompok rentan seperti anak-anak, lansia, dan ibu hamil, menjadi permasalahan utama yang memerlukan penanganan cepat dan terintegrasi. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan respons tanggap bencana melalui pendekatan Aksi Tiga Pilar, yaitu Logistik Cepat, Gizi Tepat, dan Pemberian Layanan Trauma. Metode pelaksanaan dilakukan secara partisipatif melalui tahapan persiapan dan koordinasi dengan mitra setempat, pelaksanaan kegiatan inti berupa distribusi bantuan logistik dan pangan bergizi, serta layanan trauma healing, dan diakhiri dengan monitoring serta evaluasi kegiatan. Produk bantuan yang disalurkan meliputi paket sembako, perlengkapan kebersihan, kebutuhan sandang, serta dukungan psikososial bagi masyarakat terdampak. Hasil kegiatan menunjukkan bahwa program ini mampu memenuhi kebutuhan dasar masyarakat secara cepat dan tepat sasaran, meningkatkan pemenuhan gizi terutama bagi kelompok rentan, serta membantu mengurangi tingkat stres dan trauma akibat bencana. Dengan demikian, pendekatan Aksi Tiga Pilar terbukti efektif sebagai model penanganan tanggap bencana yang holistik dan berkelanjutan dalam mendukung pemulihan fisik dan psikologis masyarakat terdampak.
PENGARUH JENIS PELARUT TERHADAP AKTIVITAS ANTIOKSIDAN EKSTRAK KULIT KAYU RARU (Cotylelobium melanoxylon (Hook.f) Pierre) MELALUI UJI DPPH Sibagariang, Nurhadijah; Bangar, Roy Indrianto; Ikhtiari, Refi
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 9 No. 2 (2026): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v9i2.2181

Abstract

Co-Authors Afifah Ikhwan AHMAD RAIF Ali Napiah Nasution Ananda Putra Angie, Evelyn ARFANI ARFANI Bangar, Roy Indrianto Chrismis Novalinda Ginting Chrismis Novalinda Ginting Chrismis Novalinda Ginting Claudia Malau, Reghita Djamin Kartarino Erny Tandanu Erny Tandanu Erny Tandanu Evelyn Angie Fioni Chandra Fiska Maya Wardhani Ginting, Chrismis Novalinda Girsang, Ermi Girsang, Jakasmir Hairus Abdullah Handoko, Erwin Harahap, Viora Rezky Heryani, Dyah Wijiana Juita, Anggun Lister, I Nyoman Ehrich Martinus Ahmad Raif Maya Wardhani, Fiska Nardi, Leo Nasution, Ali Napiah Nazimuddin Putri, Nadya Purba, Windania Raif, Martinus Ahmad Rapael Ginting Sahna Ferdinand Ginting Sahna Ferdinand Ginting Sari, Laura Kartika Sibagariang, Nurhadijah Silvia Fransisca Stephanie Renata Yosefa Tandanu, Erny Tiarnida Nababan Timotius Agung Soripada Tri Lestari Simangunsong Viora Rezky Harahap William Leslie Yensuari, Yensuari