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Perilaku dengan penggunaan asam formiat dan kejadian penyakit kulit pada pekerja bagian produksi pengolahan karet PT. X Fitriani, Dini Dwi; Nardi, Leo; Hanjaya, Hanjaya; Angie, Evelyn; Fransisca, Silvia; Leslie, William; Yani, Herlina
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.633 KB)

Keluhan penyakit kulit yang dialami oleh pekerja di tempat kerja biasanyan disebabkan oleh bahan kimia dan bahan lain. Salah satu perusahaan yang menggunakan bahan kimia dalam proses reproduksinya adalah perusahan pengolahan karet. PT.X adalah salah perusahaan yang bergerak dalam proses pengolahan karet dengan menggunakan bahan kimia asam formiat dalam oengolahan nya. Diketahui bahwa dari survey awal yang dilakukan bahwa dari 7 orang yang di wawancarai 4 di antaranya mengalami keluhan gangguan kulit .Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan, sikap, dan tindakan dengan penggunaan asam formiat terhadap kejadian penyakit kulit di bagian produksi Pabrik Pengolahan Karet PT.X. Penelitian ini bersifat deskriptif analitik, dengan rancangan penelitian cross-sectional. Populasi dalam penelitian ini adalah seluruh pekerja yang bekerja di PT X. Sampel dalam penelitian ini adalah seluruh karyawan yang bekerja di bagian produksi sebanyak 42 karyawan, dengan teknik pengambilan sample secara purposive sampling. Teknik pengumpulan data dengan cara observasi dan kuesioner. Analisis data yang digunakan dalam penelitian ini adalah uji Chi-Square dengan derajat kepercayaan 95%. Berdasarkan hasil uji Chi-Square didapatkan hasil bahwa ada hubungan pengetahuan (0,014), sikap (0,006), dan tindakan (0,000) dengan penggunaan asam formiat terhadap kejadian penyakit kulit.

Gambaran klinis dan penatalaksanaan gagal ginjal kronik pada pasien rawat inap Angie, Evelyn; Amir, Widya Pasca; Janice, Janice; Nasution, Syamsul Arifin
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Gagal ginjal merupakan keadaan klinis yang ditandai dengan penurunan fungsi ginjal yang ireversibel pada suatu saat yang memerlukan terapi pengganti ginjal yang tetap seperti dialisis atau transplantasi ginjal. Penelitian ini bertujuan mengetahui gambaran kasus gagal ginjal kronik di RSU Royal Prima. Penelitian ini merupakan penelitian deskriptif retrospektif dengan desain studi kasus. Populasi seluruh data rekam medis pasien gagal ginjal kronik yang berjumlah 100. Besar sampel yang dibutuhkan diambil secara purposif. Hasil penelitian menunjukkan umur termuda 17 tahun dan tertua 78 tahun, dan kelompok umur terbanyak >60 tahun 30%. Keluhan utama terbanyak mual 28% dan penatalaksanaan terbanyak adalah hemodialisis 91%.

Test of the Effectiveness of Giving Salmon DNA Serum with Virgin Coconut Oil Extract on the Growth of Skin Tissue from Cut Scars on the Skin of Female Wistar Rats (Rattus Norvegicus) Apriani, Silvi; Angie, Evelyn; Nasution, Syamsul Arifin
Journal La Medihealtico Vol. 5 No. 1 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i1.1093

Various treatments can cure pockmarks. First, you have to know the cause of the pockmarks and the strength of the pockmarked skin, making it easier to choose the treatment, one of which is dermapen, which uses plasma from platelets. Test and compare the effectiveness of the derma pen action using platelet plasma with the derma pen action on the pockmarked skin surface of female Wistar rats (Rattus novergicus). This research is a laboratory experiment to compare the effectiveness of the dermapen action using plasma from platelets with the dermapen action on the pockmarked skin surface of female Wistar rats (Rattus novergicus) using a post-test with control group design or control samples based on treatment groups to analyze the dermapen action using plasma from platelets with dermapenic action on the surface of rat skin pockmarks. The results showed that the dermapen treatment group with plasma from platelets at a dose of 10% was more effective in healing cut wounds in white mice than the dermapen treatment group using plasma from platelets at doses of 2.5% and 5%. This is because, at a concentration of 10%, blood plasma metabolite compounds from platelets that are applied to wounds already affect the wound. The effect only inhibits microorganisms at small doses, making it less effective in healing wounds. It is recommended that the minimum dose be 10% so that the metabolite compounds in the plasma from platelets have a healing effect on wounds.

The role of family planning field extension workers (PFEW) in fertile age couples in choosing long-term contraception methods at Sekerak District Health Center Halim, Yeni; Saputri, Novia; Yuliana, Yuliana; Lubis, Ika Syani Putri; Suwarno, Suwarno; Sulistijanto, Eddy; Alexander, Rico; Fresia, Ana; Henny, Henny; Putri, Eka; Angie, Evelyn
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7451

The lack of socialization carried out by Family Planning Field Extension Workers (FPFE) leads to fear among the community, especially among Couples of Reproductive Age (CRA), in choosing Long-Term Contraception Methods (LTCM). Couples of reproductive age require health education or counseling to help them determine which contraceptive method to use. This study aims to determine the role of PLKB for couples of reproductive age (PUS) in choosing LTCM at Sekerak District Health Center, Aceh Tamiang Regency in 2022. This study is a quantitative research with a cross-sectional design. The population in this study was all couples of reproductive age in Sekerak Kanan Village, Sekerak District, Aceh Tamiang Regency, and the research sample consisted of 126 people. Data collection was done directly by distributing questionnaires to couples of reproductive age. Then, it was followed by the process of data analysis using the Chi-Square test and logistic regression. The results showed that there is a relationship between counseling quality in choosing LTCM with a value of (p=0.001; PR=3.4; 95% CI 2.201-5.294), there is a relationship between PLKB barriers in choosing LTCM with a value of (p=0.001; PR=2.2; 95% CI 1.724-3.007), and there is a relationship between FPFE capacity in choosing long-term contraceptive methods with a value of (p=0.001; PR=2.4; 95% CI 1.704-3.472). Furthermore, the dominant factor related to the selection of LTCM is counseling quality with a value of (p=0.000; PR=10.766 95% CI 3.491-33.204). Couples of reproductive age are expected to increase their knowledge, especially about long-term contraceptive methods, and it is hoped that men will not be ashamed to participate in family planning programs.

Uji Efektivitas Ekstrak Umbi Bit (Beta vulgaris) Terhadap Kontrol Gula Darah dan Gambaran Histopatologi Pankreas Pada Tikus Diabetes Yang Diinduksi Aloksan Brahmana, Lisa Charolin Br; Angie, Evelyn; Lister, Gilbert
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 9 (2025): : JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i9.4886

Diabetes mellitus is a metabolic disease characterized by increased blood sugar levels due to the body's inability to process insulin. The disease can affect a variety of organs, including the eyes, kidneys, heart, and nervous system. This study aims to evaluate the effect of ethanol extract of beet tubers on the decrease in blood sugar levels and changes in the histopathology of the pancreas. Through a true experiment design with the pretest-postest group in aloxan-induced wistar rats, the animals were divided into six groups: the normal, negative control, positive control (metformin) groups, and three treatment groups with beet tuber extract at doses of 22.5 mg/kgBB, 45 mg/kgBB, and 90 mg/kgBB. Blood glucose levels were measured on days 0, 3, 6, 9, 12, and 14. Results showed a significant difference between day-0 and day-14 (P <0.05), but there was no significant difference between the positive control group and all treatment groups (P > 0.05). Histopathology shows beet tuber extract and metformin do not provide a significant difference to the pancreas. Beet tuber extract is effective as an antidiabetic in lowering blood sugar levels in aloxan-induced rats.

Perilaku dengan penggunaan asam formiat dan kejadian penyakit kulit pada pekerja bagian produksi pengolahan karet PT. X Fitriani, Dini Dwi; Nardi, Leo; Hanjaya, Hanjaya; Angie, Evelyn; Fransisca, Silvia; Leslie, William; Yani, Herlina
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Keluhan penyakit kulit yang dialami oleh pekerja di tempat kerja biasanyan disebabkan oleh bahan kimia dan bahan lain. Salah satu perusahaan yang menggunakan bahan kimia dalam proses reproduksinya adalah perusahan pengolahan karet. PT.X adalah salah perusahaan yang bergerak dalam proses pengolahan karet dengan menggunakan bahan kimia asam formiat dalam oengolahan nya. Diketahui bahwa dari survey awal yang dilakukan bahwa dari 7 orang yang di wawancarai 4 di antaranya mengalami keluhan gangguan kulit .Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan, sikap, dan tindakan dengan penggunaan asam formiat terhadap kejadian penyakit kulit di bagian produksi Pabrik Pengolahan Karet PT.X. Penelitian ini bersifat deskriptif analitik, dengan rancangan penelitian cross-sectional. Populasi dalam penelitian ini adalah seluruh pekerja yang bekerja di PT X. Sampel dalam penelitian ini adalah seluruh karyawan yang bekerja di bagian produksi sebanyak 42 karyawan, dengan teknik pengambilan sample secara purposive sampling. Teknik pengumpulan data dengan cara observasi dan kuesioner. Analisis data yang digunakan dalam penelitian ini adalah uji Chi-Square dengan derajat kepercayaan 95%. Berdasarkan hasil uji Chi-Square didapatkan hasil bahwa ada hubungan pengetahuan (0,014), sikap (0,006), dan tindakan (0,000) dengan penggunaan asam formiat terhadap kejadian penyakit kulit.

Gambaran klinis dan penatalaksanaan gagal ginjal kronik pada pasien rawat inap Angie, Evelyn; Amir, Widya Pasca; Janice, Janice; Nasution, Syamsul Arifin
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v1i1.2621

Gagal ginjal merupakan keadaan klinis yang ditandai dengan penurunan fungsi ginjal yang ireversibel pada suatu saat yang memerlukan terapi pengganti ginjal yang tetap seperti dialisis atau transplantasi ginjal. Penelitian ini bertujuan mengetahui gambaran kasus gagal ginjal kronik di RSU Royal Prima. Penelitian ini merupakan penelitian deskriptif retrospektif dengan desain studi kasus. Populasi seluruh data rekam medis pasien gagal ginjal kronik yang berjumlah 100. Besar sampel yang dibutuhkan diambil secara purposif. Hasil penelitian menunjukkan umur termuda 17 tahun dan tertua 78 tahun, dan kelompok umur terbanyak >60 tahun 30%. Keluhan utama terbanyak mual 28% dan penatalaksanaan terbanyak adalah hemodialisis 91%.

The role of family planning field extension workers (PFEW) in fertile age couples in choosing long-term contraception methods at Sekerak District Health Center Halim, Yeni; Saputri, Novia; Yuliana, Yuliana; Lubis, Ika Syani Putri; Suwarno, Suwarno; Sulistijanto, Eddy; Alexander, Rico; Fresia, Ana; Henny, Henny; Putri, Eka; Angie, Evelyn
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7451

The lack of socialization carried out by Family Planning Field Extension Workers (FPFE) leads to fear among the community, especially among Couples of Reproductive Age (CRA), in choosing Long-Term Contraception Methods (LTCM). Couples of reproductive age require health education or counseling to help them determine which contraceptive method to use. This study aims to determine the role of PLKB for couples of reproductive age (PUS) in choosing LTCM at Sekerak District Health Center, Aceh Tamiang Regency in 2022. This study is a quantitative research with a cross-sectional design. The population in this study was all couples of reproductive age in Sekerak Kanan Village, Sekerak District, Aceh Tamiang Regency, and the research sample consisted of 126 people. Data collection was done directly by distributing questionnaires to couples of reproductive age. Then, it was followed by the process of data analysis using the Chi-Square test and logistic regression. The results showed that there is a relationship between counseling quality in choosing LTCM with a value of (p=0.001; PR=3.4; 95% CI 2.201-5.294), there is a relationship between PLKB barriers in choosing LTCM with a value of (p=0.001; PR=2.2; 95% CI 1.724-3.007), and there is a relationship between FPFE capacity in choosing long-term contraceptive methods with a value of (p=0.001; PR=2.4; 95% CI 1.704-3.472). Furthermore, the dominant factor related to the selection of LTCM is counseling quality with a value of (p=0.000; PR=10.766 95% CI 3.491-33.204). Couples of reproductive age are expected to increase their knowledge, especially about long-term contraceptive methods, and it is hoped that men will not be ashamed to participate in family planning programs.

Effectiveness of Mango Mistletoe on Lung Superoxide Dismutase in Hypertensive Rats Exposed to DOCA-Salt Darma, Surya; Angie, Evelyn; Lubis, Yuliani Mardiati; Muharraran, Firdha
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 4 (2024): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i4.3676

Vascular disease, caused by oxidative stress and endothelial cell inflammation during hypertension's development, produces substantial mortality and morbidity. Mango mistletoe was tested for its effect on pulmonary superoxide dismutase (SOD) in hypertensive rats exposed to DOCA-salt in a preventative model. This study involves experimental quantitative research. SPSS was used for one-way ANOVA and post-hoc LSD testing. The population used was male Wistar rats (Rattus norvegicus). The samples used were 25 male Wistar rats divided into five treatment groups because of the Shapiro-Wilk test for normality analysis. The treatment group included a negative control group, a positive control group, and a group given different doses of mango mistletoe methanol extract: P1 at 75 mg/kgBW, P2 and P3 at 150 mg/kgBW, and P3 at 250 mg/kgBW. The study indicated that 250 mg/kg BW mango mistletoe extract increased SOD levels in DOCA-Garam-exposed Wistar white rats (Rattus norvegicus). Enhanced superoxide dismutase, malondialdehyde (MDA), ureum, creatinine, and renal histology see this. The normality of study data in the complete group assessing SOD, MDA, ureum, and creatinine levels showed a significance value larger than 0.05. The significance probability and one-way ANOVA test values are more than 0.05. The study found that mango mistletoe extract contains saponins, tannins, flavonoids, and triterpenoids that increase SOD levels and repair kidney cells damaged by hypertension in Wistar white rats. The study examined how mango mistletoe extract affects mouse hypertension. However, its conclusions should not be applied to humans. Clinical trials are needed to determine mango mistletoe extract's safety and efficacy for humans.

GAMBARAN FUNGSI HATI PADA PASIEN DIABETES MELITUS TIPE 2 DI RSU ROYAL PRIMA MEDAN TAHUN 2022 Ginting, Dicky Owenta; Angie, Evelyn; Natali, Oliviti
Jurnal Kesehatan Tambusai Vol. 5 No. 1 (2024): MARET 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i1.23543

Diabetes Melitus merupakan penyakit dengan tingginya kadar glukosa darah, yang merupakan sumber energi utama untuk sel tubuh. Seringkali seseorang tidak menyadari apabila orang tersebut terkena diabetes, dan terlambat dalam menanganinya sehingga terjadi komplikasi. Glukosa yang menumpuk dalam darah dapat mencetuskan berbagai gangguan pada organ tubuh. Pada pasien Diabetes Melitus (DM) tipe II terjadi peningkatan enzim hati (AST/SGOT dan ALT/SGPT) yang disebabkan karena adanya kerusakan dinding sel hati. Nilai AST dan ALT dapat digunakan untuk membantu melihat kondisi kerusakan fungsi sel hati. Tujuan penelitian ini adalah untuk mengetahui gambaran fungsi hati pada pasien Diabetes Melitus (DM) tipe II di Rumah Sakit Umum Royal Prima medan tahun 2022. Penelitian ini menggunakan desain deskriptif observasional dengan menggunakan instrument penelitian data rekam medis pasien Diabetes Melitus (DM) tipe 2 Tahun 2022. Pengambilan sampel yang digunakan dalam penelitian ini menggunakan teknik purposive sampling dengan jumlah sampel sebanyak 29 orang. Kemudian dilakukan analisis data menggunakan analisis univariat dengan perhitungan proporsi karakteristik berdasarkan variabel dengan menggunakan SPSS. Hasil penelitian menyatakan bahwa dari total 29 pasien terdapat 13 orang (44,83%) memiliki derajat SGPT ringan, 6 orang (20,69%) memiliki derajat SGOT ringan, dan 1 orang (3,45%) memiliki derajat SGOT sedang. Kesimpulan dari penelitian ini adalah pada pasien Diabetes Melitus (DM) tipe II terdapat kenaikan kadar SGOT dan SGPT.

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