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Perilaku dengan penggunaan asam formiat dan kejadian penyakit kulit pada pekerja bagian produksi pengolahan karet PT. X Fitriani, Dini Dwi; Nardi, Leo; Hanjaya, Hanjaya; Angie, Evelyn; Fransisca, Silvia; Leslie, William; Yani, Herlina
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.633 KB)

Keluhan penyakit kulit yang dialami oleh pekerja di tempat kerja biasanyan disebabkan oleh bahan kimia dan bahan lain. Salah satu perusahaan yang menggunakan bahan kimia dalam proses reproduksinya adalah perusahan pengolahan karet. PT.X adalah salah perusahaan yang bergerak dalam proses pengolahan karet dengan menggunakan bahan kimia asam formiat dalam oengolahan nya. Diketahui bahwa dari survey awal yang dilakukan bahwa dari 7 orang yang di wawancarai 4 di antaranya mengalami keluhan gangguan kulit .Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan, sikap, dan tindakan dengan penggunaan asam formiat terhadap kejadian penyakit kulit di bagian produksi Pabrik Pengolahan Karet PT.X. Penelitian ini bersifat deskriptif analitik, dengan rancangan penelitian cross-sectional. Populasi dalam penelitian ini adalah seluruh pekerja yang bekerja di PT X. Sampel dalam penelitian ini adalah seluruh karyawan yang bekerja di bagian produksi sebanyak 42 karyawan, dengan teknik pengambilan sample secara purposive sampling. Teknik pengumpulan data dengan cara observasi dan kuesioner. Analisis data yang digunakan dalam penelitian ini adalah uji Chi-Square dengan derajat kepercayaan 95%. Berdasarkan hasil uji Chi-Square didapatkan hasil bahwa ada hubungan pengetahuan (0,014), sikap (0,006), dan tindakan (0,000) dengan penggunaan asam formiat terhadap kejadian penyakit kulit.

Gambaran klinis dan penatalaksanaan gagal ginjal kronik pada pasien rawat inap Angie, Evelyn; Amir, Widya Pasca; Janice, Janice; Nasution, Syamsul Arifin
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Gagal ginjal merupakan keadaan klinis yang ditandai dengan penurunan fungsi ginjal yang ireversibel pada suatu saat yang memerlukan terapi pengganti ginjal yang tetap seperti dialisis atau transplantasi ginjal. Penelitian ini bertujuan mengetahui gambaran kasus gagal ginjal kronik di RSU Royal Prima. Penelitian ini merupakan penelitian deskriptif retrospektif dengan desain studi kasus. Populasi seluruh data rekam medis pasien gagal ginjal kronik yang berjumlah 100. Besar sampel yang dibutuhkan diambil secara purposif. Hasil penelitian menunjukkan umur termuda 17 tahun dan tertua 78 tahun, dan kelompok umur terbanyak >60 tahun 30%. Keluhan utama terbanyak mual 28% dan penatalaksanaan terbanyak adalah hemodialisis 91%.

Test of the Effectiveness of Giving Salmon DNA Serum with Virgin Coconut Oil Extract on the Growth of Skin Tissue from Cut Scars on the Skin of Female Wistar Rats (Rattus Norvegicus) Apriani, Silvi; Angie, Evelyn; Nasution, Syamsul Arifin
Journal La Medihealtico Vol. 5 No. 1 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i1.1093

Various treatments can cure pockmarks. First, you have to know the cause of the pockmarks and the strength of the pockmarked skin, making it easier to choose the treatment, one of which is dermapen, which uses plasma from platelets. Test and compare the effectiveness of the derma pen action using platelet plasma with the derma pen action on the pockmarked skin surface of female Wistar rats (Rattus novergicus). This research is a laboratory experiment to compare the effectiveness of the dermapen action using plasma from platelets with the dermapen action on the pockmarked skin surface of female Wistar rats (Rattus novergicus) using a post-test with control group design or control samples based on treatment groups to analyze the dermapen action using plasma from platelets with dermapenic action on the surface of rat skin pockmarks. The results showed that the dermapen treatment group with plasma from platelets at a dose of 10% was more effective in healing cut wounds in white mice than the dermapen treatment group using plasma from platelets at doses of 2.5% and 5%. This is because, at a concentration of 10%, blood plasma metabolite compounds from platelets that are applied to wounds already affect the wound. The effect only inhibits microorganisms at small doses, making it less effective in healing wounds. It is recommended that the minimum dose be 10% so that the metabolite compounds in the plasma from platelets have a healing effect on wounds.

The Effect of Swimming Aerobic Physical Exercise On White Rats (Rattus Novergicus) Of the Wistar Strain That Are Obese Altamira, Vita; Angie, Evelyn; Kunardi, Sidharta
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 3 (2024): August 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.321

Women are more likely to be obese and at risk of hypertension and coronary heart disease than men. Genetic factors influence it. Physical exercise can reduce obesity, especially on endothelial factors such as ET-1 and NO. This research explores the effect of swimming physical training on the expression of endothelin-1 and receptor-A in obese mouse models. This type of research is a true experiment carried out on 12 adult female Wistar rats (Rattus norvegicus) as research samples. The research procedures were carried out by caring for test animals, raising rats until they were obese, not giving treatment (control), physical training in the form of swimming exercises, and finally, examination of ET-1, ET-A, blood sugar levels, and total cholesterol levels. The data obtained was analyzed using SPSS. The research results of the normality test for the treatment group were more significant than 0.05 in the ET-1 examination of 0.315 and ET-A of 0.261. ET-1 levels were 92.5 pg/ml and ET-A levels were 62.5 pg/ml. Their blood sugar level was 167 mg/dL. The research concluded that in mouse tests, physical training was better for increasing ET-1 levels and reducing ET-A levels. Swimming and aerobics are better at lowering blood sugar levels.

Correlation Between Axial Length and Amplitude of Accommodation in Myopia Patients Angie, Evelyn; Amra, Aryani Atiyatul; Sari, Masitha Dewi
Journal of Public Health and Pharmacy Vol. 4 No. 3: NOVEMBER 2024
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v4i3.5576

Background: Myopia is the most common refractive disorder and is a global concern because it can cause more serious eye problems. Excessive prolonged axial growth of the eyeball can lead to myopia. The amplitude of accommodation is the strength of the eye accommodation during the minimum and maximum accommodation conditions. Based on the above data, the researchers wanted to assess the relationship between eyeball length and accommodation amplitude in myopia patients. Method: The research was conducted at the Hospital of Prof CPL University of North Sumatra from November 2023 to March 2024. Data analysis was done analytically and presented in the form of data tabulation. Result: This study included 54 myopia patients, 27 males and 27 females, who visited the eye clinic. The mean age of the subjects was (52%). The mean age of the subjects was 23 years old with the youngest being 22 years old and the oldest being 24 years old. The mean of axial length for mild myopia, moderate myopia and severe myopia were 24.51 cm, 25.75 cm and 28.38 cm respectively. The lowest NPA value was found in severe myopia (27.33 cm) and the highest in mild myopia (43 cm). The lowest NPC value was found in mild myopia (36.61 cm) and the highest in severe myopia (38.56 cm). There was a significant relationship between eyeball length and accommodation amplitude with a Spearman correlation value of -0.685 as well as after cycloplegic administration with a Spearman correlation value of 0.438. NPA values showed an increase when receiving spherical correction, whether accompanied by cycloplegics or not, and a decrease when not receiving spherical correction. NPC values showed a decrease in all treatments. Conclusion: There is a correlation between axial length and amplitude of accomodation values (NPA and NPC) in patients with myopia.

The role of family planning field extension workers (PFEW) in fertile age couples in choosing long-term contraception methods at Sekerak District Health Center Halim, Yeni; Saputri, Novia; Yuliana, Yuliana; Lubis, Ika Syani Putri; Suwarno, Suwarno; Sulistijanto, Eddy; Alexander, Rico; Fresia, Ana; Henny, Henny; Putri, Eka; Angie, Evelyn
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7451

The lack of socialization carried out by Family Planning Field Extension Workers (FPFE) leads to fear among the community, especially among Couples of Reproductive Age (CRA), in choosing Long-Term Contraception Methods (LTCM). Couples of reproductive age require health education or counseling to help them determine which contraceptive method to use. This study aims to determine the role of PLKB for couples of reproductive age (PUS) in choosing LTCM at Sekerak District Health Center, Aceh Tamiang Regency in 2022. This study is a quantitative research with a cross-sectional design. The population in this study was all couples of reproductive age in Sekerak Kanan Village, Sekerak District, Aceh Tamiang Regency, and the research sample consisted of 126 people. Data collection was done directly by distributing questionnaires to couples of reproductive age. Then, it was followed by the process of data analysis using the Chi-Square test and logistic regression. The results showed that there is a relationship between counseling quality in choosing LTCM with a value of (p=0.001; PR=3.4; 95% CI 2.201-5.294), there is a relationship between PLKB barriers in choosing LTCM with a value of (p=0.001; PR=2.2; 95% CI 1.724-3.007), and there is a relationship between FPFE capacity in choosing long-term contraceptive methods with a value of (p=0.001; PR=2.4; 95% CI 1.704-3.472). Furthermore, the dominant factor related to the selection of LTCM is counseling quality with a value of (p=0.000; PR=10.766 95% CI 3.491-33.204). Couples of reproductive age are expected to increase their knowledge, especially about long-term contraceptive methods, and it is hoped that men will not be ashamed to participate in family planning programs.

Uji Efektivitas Ekstrak Umbi Bit (Beta vulgaris) Terhadap Kontrol Gula Darah dan Gambaran Histopatologi Pankreas Pada Tikus Diabetes Yang Diinduksi Aloksan Brahmana, Lisa Charolin Br; Angie, Evelyn; Lister, Gilbert
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 9 (2025): : JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i9.4886

Diabetes mellitus is a metabolic disease characterized by increased blood sugar levels due to the body's inability to process insulin. The disease can affect a variety of organs, including the eyes, kidneys, heart, and nervous system. This study aims to evaluate the effect of ethanol extract of beet tubers on the decrease in blood sugar levels and changes in the histopathology of the pancreas. Through a true experiment design with the pretest-postest group in aloxan-induced wistar rats, the animals were divided into six groups: the normal, negative control, positive control (metformin) groups, and three treatment groups with beet tuber extract at doses of 22.5 mg/kgBB, 45 mg/kgBB, and 90 mg/kgBB. Blood glucose levels were measured on days 0, 3, 6, 9, 12, and 14. Results showed a significant difference between day-0 and day-14 (P <0.05), but there was no significant difference between the positive control group and all treatment groups (P > 0.05). Histopathology shows beet tuber extract and metformin do not provide a significant difference to the pancreas. Beet tuber extract is effective as an antidiabetic in lowering blood sugar levels in aloxan-induced rats.

Test of Effectiveness of Beet Tuber Extract (Beta Vulgaris) Extract On Cholesterol Levels and Kidney Histopathology In Aloxan-Induced Diabetic Rats Jesika, Jesika; Angie, Evelyn; Gilbert Lister
Eduvest - Journal of Universal Studies Vol. 5 No. 9 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i9.52222

Objective: To evaluate the effectiveness of beetroot extract on total cholesterol levels and kidney histopathology in alloxan-induced diabetic white rats (Rattus norvegicus).Methods: This experimental study used a post-test only control group design with 24 male rats divided into six groups: normal, negative control (alloxan + aquadest), positive control (alloxan + metformin), and three treatment groups receiving beetroot extract at doses of 22.5 mg/200 gBW, 45 mg/200 gBW, and 90 mg/200 gBW. Total cholesterol levels were measured before and after treatment, while kidney tissues were examined histopathologically using HE staining and damage scoring (0–3). Data analysis included Shapiro-Wilk, Kruskal-Wallis, and Spearman’s correlation tests.Results: Most groups showed an increase in cholesterol levels after treatment, except treatment group 2 (45 mg/200 gBW), which demonstrated a decrease from 96.40 mg/dL to 84.40 mg/dL. Kruskal-Wallis test revealed no statistically significant differences among groups (p = 0.306). Histopathological findings indicated that treatment group 2 exhibited lower kidney damage scores compared to the negative control, suggesting a protective effect. Spearman’s correlation analysis showed no significant relationship between day-14 blood glucose levels and total cholesterol (r = –0.130; p = 0.492). Conclusion: Beetroot extract at a dose of 45 mg/200 gBW demonstrated potential in lowering total cholesterol levels and providing nephroprotective effects, although the results were not statistically significant. These findings support the potential role of beetroot as an adjuvant therapy in diabetes mellitus with dyslipidemia and kidney complications.

Perilaku dengan penggunaan asam formiat dan kejadian penyakit kulit pada pekerja bagian produksi pengolahan karet PT. X Fitriani, Dini Dwi; Nardi, Leo; Hanjaya, Hanjaya; Angie, Evelyn; Fransisca, Silvia; Leslie, William; Yani, Herlina
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Keluhan penyakit kulit yang dialami oleh pekerja di tempat kerja biasanyan disebabkan oleh bahan kimia dan bahan lain. Salah satu perusahaan yang menggunakan bahan kimia dalam proses reproduksinya adalah perusahan pengolahan karet. PT.X adalah salah perusahaan yang bergerak dalam proses pengolahan karet dengan menggunakan bahan kimia asam formiat dalam oengolahan nya. Diketahui bahwa dari survey awal yang dilakukan bahwa dari 7 orang yang di wawancarai 4 di antaranya mengalami keluhan gangguan kulit .Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan, sikap, dan tindakan dengan penggunaan asam formiat terhadap kejadian penyakit kulit di bagian produksi Pabrik Pengolahan Karet PT.X. Penelitian ini bersifat deskriptif analitik, dengan rancangan penelitian cross-sectional. Populasi dalam penelitian ini adalah seluruh pekerja yang bekerja di PT X. Sampel dalam penelitian ini adalah seluruh karyawan yang bekerja di bagian produksi sebanyak 42 karyawan, dengan teknik pengambilan sample secara purposive sampling. Teknik pengumpulan data dengan cara observasi dan kuesioner. Analisis data yang digunakan dalam penelitian ini adalah uji Chi-Square dengan derajat kepercayaan 95%. Berdasarkan hasil uji Chi-Square didapatkan hasil bahwa ada hubungan pengetahuan (0,014), sikap (0,006), dan tindakan (0,000) dengan penggunaan asam formiat terhadap kejadian penyakit kulit.

Gambaran klinis dan penatalaksanaan gagal ginjal kronik pada pasien rawat inap Angie, Evelyn; Amir, Widya Pasca; Janice, Janice; Nasution, Syamsul Arifin
Buletin Kedokteran & Kesehatan Prima Vol. 1 No. 1 (2022): Maret
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v1i1.2621

Gagal ginjal merupakan keadaan klinis yang ditandai dengan penurunan fungsi ginjal yang ireversibel pada suatu saat yang memerlukan terapi pengganti ginjal yang tetap seperti dialisis atau transplantasi ginjal. Penelitian ini bertujuan mengetahui gambaran kasus gagal ginjal kronik di RSU Royal Prima. Penelitian ini merupakan penelitian deskriptif retrospektif dengan desain studi kasus. Populasi seluruh data rekam medis pasien gagal ginjal kronik yang berjumlah 100. Besar sampel yang dibutuhkan diambil secara purposif. Hasil penelitian menunjukkan umur termuda 17 tahun dan tertua 78 tahun, dan kelompok umur terbanyak >60 tahun 30%. Keluhan utama terbanyak mual 28% dan penatalaksanaan terbanyak adalah hemodialisis 91%.

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