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DEPRESI PADA LANSIA PENDERITA DIABETES MELITUS TIPE 2 DI RUMAH SAKIT UMUM DAERAH DR. TENGKU MANSYUR TANJUNGBALAI TAHUN 2015 Nur Astari; OK Yulizal; Armon Rahimi; Herlina yani; Anita Rosari; Wika Hanida; Yensuari -
PRIMER (Prima Medical Journal) Vol. 7 No. 1 (2022): Edisi April
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/pmj.v7i1.2788

Abstract

Hiperglikemik merupakan keadaan adanya defek pada sekresi atau kerja  insulin yang dapat berakibat diabetes melitus. Diabetes yang berlangsung lama memungkinkan pasien mengalami depresi  yang ditandai dengan mood tertekan, kehilangan kesenangan atau minat, perasaan bersalah atau harga diri rendah, gangguan makan atau tidur, kurang energi, dan konsentrasi yang rendah. Tujuan: Penelitian ini bertujuan untuk mengetahui ada atau tidaknya depresi pada penderita lansia dengan diabetes melitus tipe 2. Metode: Penelitian analitik dengan desain cross sectional study dan case control. Data diperoleh dengan menggunakan kuesioner yang dibagikan kepada lansia yang menderita DM dan non DM. Hasil: Subyek dalam penelitian ini berjumlah 176 orang lansia, terdiri dari 88 kelompok kasus (DM) dan 88 kelompok kontrol (non DM), didapatkan penderita DM yang paling banyak mengalami depresi berjenis kelamin laki-laki berjumlah 31 orang, non depresi terbanyak pada perempuan 22 orang. Mereka yang menderita DM 1,9 kali lebih beresiko untuk mengalami depresi dibanding non DM (OR = 1,9 (interval keyakinan 95%) 1,044 - 3,457, P = 0,036). Rerata lama penyakit pada subyek yang depresi antara DM dan non DM berbeda bermakna (5,51 ± 2,66 vs 3,54 ± 2,22, P = 0,000). Rerata KGD pada penderita DM yang depresi dibanding non depresi berbeda bermakna (310,31 ± 101,01 vs 262,89 ± 92,78, P = 0,029). Rerata lama penyakit untuk tingkatan depresi (ringan, sedang, berat) berbeda secara bermakna (3,00 ± 0,00 vs 4,97 ± 2,36 vs 7,06 ± 2,70, P = 0,000). Kesimpulan: Lansia penderita DM lebih beresiko mengalami depresi dibanding lansia non DM. Rerata lama penyakit pada subyek yang depresi antara DM dan non DM berbeda bermakna. Rerata KGD pada penderita DM yang depresi dibanding non depresi berbeda bermakna. Rerata lama penyakit untuk tingkatan depresi (ringan, sedang, berat) berbeda secara bermakna.
Level Of Anxiety In Patients Undergoing Elective Gastroscopy With General And Local Anesthesia Audrey Yohan Agnes*; OK Yulizal; Yensuari Yensuari
Riwayat: Educational Journal of History and Humanities Vol 6, No 3 (2023): Social, Political, and Economic History
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v6i3.34245

Abstract

Gastrointestinal endoscopy involves the examination of the mucous membranes of the esophagus, stomach, and duodenum using an instrument equipped with a camera to provide visual images. This procedure has numerous clinical applications, including accurate diagnosis and effective guidance for upper gastrointestinal tract conditions. Insufficient patient knowledge about the impending procedure, potential procedural side effects, or anticipated examination outcomes can lead to heightened anxiety of the patient. This study aims to assess the level of anxiety in patients undergoing gastroscopy. An observational analytical study was conducted using a cross-sectional design, based on the Hamilton Anxiety Rating Scale (HARS) questionnaire. Moderate anxiety was found in 25 individuals (50%) among patients undergoing gastroscopy with local anesthesia. Meanwhile, among patients undergoing gastroscopy with general anesthesia, 15 individuals (30%) exhibited mild anxiety, and 5 individuals (10%) had moderate anxiety. There is a discernible difference in anxiety levels between patients undergoing elective gastroscopy with general anesthesia and those receiving local anesthesia.
Uji efektifitas antibakteri ekstrak daun jambu biji (Psidium guajava) terhadap pertumbuhan bakteri Bacillus cereus Natali, Oliviti; Tarigan, Antje Irmella; Sarumpaet, Elpina; Salim, Susanto; Dewani, Yunita; Hanida, Wika; Yensuari, Yensuari
Jurnal Prima Medika Sains Vol. 3 No. 1 (2021): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v3i1.1776

Abstract

Jambu biji (Psidium guajava L) secara medis banyak mengandung senyawa kimia yang berkhasiat (flavonoid, saponin, tanin, alkaloid dan minyak atsiri). Senyawa-senyawa tersebut diduga mampu menghambat pertumbuhan Bacillus cereus, yakni bakteri yang mengkontaminasi makanan serta menghasilkan racun penyebab diare. Tujuan penelitian ini untuk mendeskripsikan pengaruh ekstrak daun jambu biji terhadap pertumbuhan Bacillus cereus serta menentukan konsentrasi ekstrak daun jambu biji yang paling optimal dalam menghambat pertumbuhan bakteri Bacillus cereus. Penelitian ini menggunakan rancangan sistematis lengkap dengan 13 perlakuan dengan 3 pengulangan, yaitu pemberian kontrol negatif, kontrol positif, ekstrak murni, serta ekstrak daun jambu biji dengan pelarut 10%, 20%, 30%, 40%, 50%, 60%,70%, 80%, 90% dan 100%. Data yang diperoleh berupa diameter zona hambat, dianalisis menggunakan uji Kruskall Wallis. Hasil penelitian menunjukkan bahwa ekstrak daun jambu biji pada semua konsentrasi berpengaruh pada pertumbuhan Bacillus cereus dengan konsentrasi paling optimal yaitu sampai 100% yang menghasilkan diameter zona hambat sebesar 13 mm. Hasil penelitian juga menunjukkan bahwa semakin tinggi konsentrasi ekstrak daun jambu biji, maka daya hambatnya terhadap pertumbuhan Bacillus cereus juga semakin tinggi.
Effectiveness Of Red Betel Leaf Ointment (Piper Crocatum, Ruiz & Pav) On Slash Wounds In White Mice Yensuari, Yensuari; Andriani, Andriani
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 2 (2024): May 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.247

Abstract

Normal wounds may heal on their own in some cases, but if there are obstructions in the way, the wound won't heal, making them more difficult to treat. The purpose of this study was to evaluate the phytochemical makeup of red betel plant leaves and the effectiveness of red betel extract in accelerating wound healing in white mice. 25 male white mice made up the animal population, which was divided into 5 groups, including 3 treatment groups. using red betel extract percentages of 15%, 30%, 45%, and 10%. a pair of control groups, one positive and the other negative. The control utilized a gel-based solution and 10% povidone iodine. The white mice's backs were cut into using a 1 cm2 incision. The data was gathered by observing the entire wound healing procedure from the inflammatory phase (redness, edema, and pus presence) through the proliferative phase. The current data were then assessed using a method called the Test of Homogeneity of Variances. The One Way Anova test is useful for determining whether or not there are meaningful changes in the data variance if the prerequisites for the parametric test are met. If the p value is less than or equal to 0.05, this test is significant. The LSD post hoc test also determines the most significant set of data. When testing the distribution, if abnormal data are discovered, another alternative method is using the Kruskal-Wallis test, which is followed by the Mann-Whitney test with a significant value of 0.05. Between the positive and negative control groups, redness (p=0.003), granulation tissue (p=0.038) on the third day, and wound area reduction (p=0.048) on the ninth day were all significantly different when red betel extract concentrations of 15%, 30%, and 45% were used. It may be concluded that giving white mice betel extract at a concentration of 46% accelerates the healing of wounds. According to phytochemical analysis, red betel extract contains alkaloids, flavonoids, saponins, and tannins, making it a potential natural antioxidant.
Comparison Of Skin Hydration Levels Given Watermelon (Citrullus Lanatus) Fruit Extract Moisturizing Cream With Moisturizing Cream Supplemented With Saccharide Isomerates On Dry Skin Of Female Wistar Rats (Rattus Norvegicus) Yuliasari, Dinda; Yensuari, Yensuari; Isnanta, Rahmad
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 4 (2023): November 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i4.303

Abstract

Starting early to care for your skin can prevent premature aging. Since the skin is the body's outermost organ, The skin protects interior organs from pollution, UV radiation, and diseasecausing microbes. Research is needed to confirm and maximize topical plant treatment and skin health medication benefits. This study employs an experimental approach, testing the effects of a moisturizing cream formulated with either watermelon (Citrullus lanatus) extract or a control group of saccharide isomerates on the skin of 25 rats (Rattus norvegicus). The research results show watermelon extract can be used as a medicine since it contains antioxidants and moisturizes the skin. A higher dose of watermelon extract and saccharide isomerate includes more chemical components that hydrate skin. 30% watermelon extract cream with 5% saccharide isomerate improved dry skin more after UVB exposure.
Topical Application of Paraboea leuserensis on Excision Wound with Angiogenesis and Vascular Endothelial Growth Factor Analysis Heryani, Dyah Wijiana; Maya Wardhani, Fiska; Yensuari; Nazimuddin Putri, Nadya; Nardi, Leo; Ikhtiari, Refi
HAYATI Journal of Biosciences Vol. 31 No. 2 (2024): March 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.2.300-316

Abstract

Gagatan harimau or Paraboea leuserensis B.L. Burtt is an endemic plant that grows in limestone areas, natively found in Leuser Mountain Area, North Sumatra Province, Indonesia. This study determines the wound healing potential of P. leuserensis gel-based ethanolic extract (PGEE) on full-thickness excision wounds based on the angiogenesis and VEGF expression. Here, we reported 67 compounds detected by LC-MS/MS from the ethanolic extract. The antibacterial activity regarding pathogenic wound infection was also investigated. The experimental study used 30 Rattus novergicus, randomly divided into five treatment groups: base gel as a negative control, Bioplacenton as a positive control, PGEE 2.5%, 5%, and 10%. Experimental data showed that PGEE indicated a significant effect on bacterial inhibition (p = 0.02), where the greatest inhibitory was found against S. epidermidis. Topical application of PGEE showed significant differences in the number of blood vessels of PGEE 2.5% and 10% (p = 0.007) and expression of VEGF (p<0.05). The correlation between the number of blood vessels and VEGF was also described with the number of macrophages, fibroblasts, collagen, and wound diameter. Overall, this study demonstrates the pharmacological potential of PGEE for wound healing applications regarding angiogenesis and VEGF expression.
Pengaruh Kendali Glukosa Darah, Hipertensi, Dan Dislipidemia Terhadap Komplikasi Retinopati Diabetik Pada Penderita Diabetes Melitus Tipe 2 Raflin BR Sinaga, May; Yensuari, Yensuari; Dharma, Surya
Jurnal Multidisiplin Indonesia Vol. 2 No. 10 (2023): Jurnal Multidisiplin Indonesia
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jmi.v2i10.608

Abstract

Jumlah atau frekuensi kasus diabetes melitus tipe 2 dari berbagai data menunjukkan peningkatan di berbagai penjuru dunia. Peningkatan prevalensi diabetes melitus berdampak pada komplikasi diabetes melitus. Salah satu komplikasi yang umum terjadi pada pasien diabetes melitus tipe 2 yaitu retinopati diabetik, di mana kerusakan pembuluh darah mikro di retina dapat menyebabkan gangguan penglihatan hingga kebutaan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh kendali glukosa darah, hipertensi, dan dislipidemia terhadap komplikasi retinopati diabetik pada penderita diabetes melitus tipe 2. Jenis penelitian yang digunakan adalah penelitian deskriptif observasional. Populasi pada penelitian ini yaitu semua penderita diabetes melitus tipe 2 yang terdaftar dalam rekam medik di RS Mata Sumatera Eye Center (SMEC) Medan tahun 2022 sebanyak 429 orang. Sampel yang didapatkan dalam penelitian ini sebanyak 255 rekam medis. Penarikan sampel secara purposive sampling. Data dianalisis secara univariat dan bivariat menggunakan uji Chi-Square pada taraf kepercayaan 95% (a=0,05) dan nilai Prevalence Ratio (PR). Hasil penelitian menunjukkan bahwa faktor yang berpengaruh terhadap komplikasi retinopati diabetik pada penderita DM tipe 2 di Rumah Sakit Mata Sumatera Eye Center (SMEC) tahun 2022 yaitu kendali glukosa darah (HbA1c) (p < 0,001; PR = 1,857), hipertensi (p < 0,001; PR = 2,016), dan dislipidemia/LDL (p = 0,007; PR = 1,327). Disarankan Pihak Rumah Sakit Mata SMEC berkolaborasi antara tim medis dengan memastikan pendekatan holistik dalam pencegahan dan manajemen retinopati diabetik pada pasien DM.
The relationship between workload and musculoskeletal complaints among opak factory workers in Sukaraya Bakti Village, Pancur Batu Hutapea, Johnson; Pakpahan, Estriyana; Rosari, Anita; Meilani, Inda Kania; Yensuari, Yensuari; Yani, Herlina; Rahimi, Armon; Rajagukguk, Samuel Joshua Hamonangan Tua; Amir, Dwi Fenny; Alponso, Rudolf; Elizabeth, Monalisa
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7439

Abstract

Based on industrial processes that still use semi-automatic processes, this often causes health problems, such as musculoskeletal problems or disorders in workers due to semi-automatic production processes and heavy loads. The aim is to find out the relationship between workload and musculoskeletal complaints in Opak Village factory workers. Sukaraya Bakti, District. Pancur Batu, Kab. Deli Serdang. The research method carried out here is quantitative descriptive research. Where this research tries to explore how and why this health phenomenon occurs. This descriptive research was carried out using observation and interview methods. Observations and interviews were carried out on several behavioral factors, which were then linked to musculoskeletal complaints in opak makers. It can be concluded that there is a significant relationship between workload and complaints of musculoskeletal disorders among Opak Factory Workers in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency.
The relationship between workload and musculoskeletal complaints among opak factory workers in Sukaraya Bakti Village, Pancur Batu Hutapea, Johnson; Pakpahan, Estriyana; Rosari, Anita; Meilani, Inda Kania; Yensuari, Yensuari; Yani, Herlina; Rahimi, Armon; Rajagukguk, Samuel Joshua Hamonangan Tua; Amir, Dwi Fenny; Alponso, Rudolf; Elizabeth, Monalisa
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7439

Abstract

Based on industrial processes that still use semi-automatic processes, this often causes health problems, such as musculoskeletal problems or disorders in workers due to semi-automatic production processes and heavy loads. The aim is to find out the relationship between workload and musculoskeletal complaints in Opak Village factory workers. Sukaraya Bakti, District. Pancur Batu, Kab. Deli Serdang. The research method carried out here is quantitative descriptive research. Where this research tries to explore how and why this health phenomenon occurs. This descriptive research was carried out using observation and interview methods. Observations and interviews were carried out on several behavioral factors, which were then linked to musculoskeletal complaints in opak makers. It can be concluded that there is a significant relationship between workload and complaints of musculoskeletal disorders among Opak Factory Workers in Sukaraya Bakti Village, Pancur Batu District, Deli Serdang Regency.