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Fibrini, Dewi
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Journal : Eduvest - Journal of Universal Studies

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A Comparison Between The Administration of Povidone Iodine 10% and Aloe Vera Gel on The Healing of Wistar Rat Burns (Rattus Norvegicus) Felicia, Jesselyn; Fibrini, Dewi; Dalimunthe, Anita Rosari
Eduvest - Journal of Universal Studies Vol. 4 No. 12 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i12.50002

Abstract

Aloe vera has long been known for its diverse properties, including wound healing. Compounds such as saponins, tannins, and polyphenols contained in aloe vera provide anti-inflammatory, antibacterial, and accelerate tissue regeneration. This study aims to compare the effectiveness between Povidone Iodine 10% and Aloe Vera Gel on burn wound healing in Wistar Rats (Rattus norvegicus). The study used an experimental design with post-test only control group design. A total of 33 rats were divided into three groups: control group without treatment, Povidone Iodine 10% group, and Aloe Vera Gel group. Observations were made on days 0, 7, and 14 with parameters of wound diameter, percentage of wound reduction, and histopathological analysis to assess the amount of blood vessel formation, fibroblasts, macrophages, and epidermal thickness. The results showed that the administration of Aloe Vera Gel is effective in healing burn wounds, especially in the inflammatory and proliferation phases.
Co-Authors Ayuarianti, Ayuarianti Dalimunthe, Anita Rosari Edlin, Edlin Felicia, Jesselyn Fioni, Fioni Fitriani, Anche Pratiwi Francesco, Francesco Ginting, Rapael Intan Ruspita, Intan Lina, Juliana Loviana Hasibuan, Soya Lumbantobing, Christina JRE. Manulang, Ony Veronika Meldawati Meldawati Olidya, Desyoma Purba, Desi Natalia Reh Malem br Karo Rumahorbo, Novynsqi Saragih, Agnes Fransisca Siagian, Masryna Silaen, Mangatas Sinurat, Jhon Patar Siregar, Abdul Rahman Maulana Tjipta, Arya Wijaya, Johana Fransiska Yolanda, Eva Yulizal, Ok