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All Journal REKA KARSA Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) MAJU : Jurnal Ilmiah Pendidikan Matematika Ceria: Jurnal Program Studi Pendidikan Anak Usia Dini Jurnal Insan Farmasi Indonesia Jurnal Ilmu Keperawatan Indonesia (JIKPI) Kopula: Jurnal Bahasa, Sastra, dan Pendidikan Jurnal Sains Student Research Jurnal Mitra Teknik Industri Jurnal Vokasi Keperawatan (JVK) MPSJ
Dewi Yuliana
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Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Physics Public Health Other

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Literature Review : Perkembangan Pengobatan Kemoterapi Kanker Payudara Dewi Yuliana; Wulan Wulan
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Breast cancer is a condition where cells lose control and normal mechanisms, resulting in abnormal, fast and uncontrolled cell growth that occurs in the breast. Breast cancer is the most feared disease by women. One of the treatments is chemotherapy. The purpose of this study is to find out how the development of breast cancer chemotherapy treatment. As for the research method, this research uses literature review, in the search for literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. Where the results obtained show that chemotherapy treatment for breast cancer has developed where it has been found that monoclonal antibody therapy and gene therapy have been proven to increase disease-free expectations in breast cancer patients.
LITERATURE REVIEW : Uji Molekular Docking Senyawa Osimertinib Beserta Turunannya Terhadap Reseptor Tirosin kinase Pada kanker Paru- Paru Dewi Yuliana; Aminah Aminah; Andi Khuswatun Khazanah Ishak
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Lung cancer is all malignancy in the lung, including malignancy originating from the lung itself (primary). In clinical terms, what is meant by primary lung cancer is a malignant tumor originating from the bronchial epithelium. Current anti-lung cancer therapy has the goal of inhibiting the activity of EGFR. One of the substances that inhibits the action of EGFR is Tyrosine Kinase Inhibitor (TKI). Osimertinib has the potential to inhibit the phosphorylation of cells containing EGFR mutations. This review article aims to determine the ability of osimertinib compounds and their derivatives as lung cancer therapeutic agents against tyrosine kinase receptors using the molecular docking method. The research method used is literature review using two databases, namely Pubmed and Google Scholar for the last 10 years from 2013-2023. And the results obtained are that Osimertinib can be used as a lung cancer therapeutic agent against tyrosine kinase receptors
STUDI PENEGTAHUAN MASYARAKAT TENTANG PENGGUNAAN ANTIBIOTIK DIDESA MANAKKU,KECAMATAN LABAKKANG KABUPATEN PANGKAJENE DAN KEPULAUAN novita annur ramadhani; Bayu Putra; Dewi Yuliana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Antibiotika adalah obat untuk mencegah dan mengobati infeksi yang disebabkan oleh bakteri, penggunaannya yang tidak tepat selain menjadi pemborosan secara ekonomi juga berbahaya secara klinik, yaitu menyebabkan resistensi bakteri terhadap antibiotik. Penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimana pengetahuan masyarakat di Desa Manakku tentang penggunaan antibiotik Responden yang digunakan oleh peneliti yaitu masyarakat yang berdomisili di desa manakku kecamatan labakkang kabupaten pangkajene dan kepulauan dengan proyeksi jumlah penduduk 1.400 jiwa. Setelah di kategorikan berdasarkan dengan kriteria inklusi dan ekslusi sehingga diperoleh data akhir untuk responden yang memenuhi kriteria tersebut yaitu 71 responden. Berdasarkan hasil tersebut tingkat pengetahuan masyarakat tentang penggunaan antibiotik di Desa Manakku sebagian besar responden yaitu 32 responden dengan (45,0%) memiliki pengetahuan cukup. Angka ini menunjukkan bahwa tingkat pengetahun responden tersebut masuk tergolong cukup.
Literatur Review : Studi Penggunaan Antibiotik Terhadap Pasien Ulkus Diabetikum Dewi Yuliana; Nur Hasmi; Andi Maulana Lolo
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Diabetic ulcers are open wounds on the surface of the skin due to macroangiopathy complications resulting in vascular insufficiency and neuropathy, and can develop into infections due to the entry of germs or bacteria and the presence of high blood sugar which is a strategic place for the growth of germs so that an amputation can occur if blood sugar is too low. the higher it is. The purpose of this study is to find out how the development of treatment using antibiotics for diabetic ulcer disease. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. In contrast to previous studies, this study focuses on the development of treatment using antibiotics in the latest diabetic ulcer patients. The amount of literature used is 13 journal articles. Where the results showed that conservative treatment such as long-term oral and parenteral antibiotics proved effective in patients with diabetic foot ulcers, negative pressure wound therapy methods, Moist Wound Healing, silver type antimicrobials (ActicoatTM), dressings have proven effective in patients.
Literature Review : Studi Rasionalitas Penggunaan Obat Antidibetes Pada Penyakit Diabetes Melitus Tipe 2 Yang Mengalami Komplikasi Nefropati Dewi Yuliana; Athifah Athifah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Diabetes melitus merupakan penyakit yang ditandai dengan peningkatan kadar glukosa dalam darah atau melebihi batas normal. Pada penyakit diabetes melitus yang tidak terkontrol akan menyebabkan terjadinya berbagai komplikasi kronik pada pasien diabetes salah satunya yaitu nefropati diabetik. Tujuan penelitian ini yaitu untuk mengetahui rasionalistas penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun metode penelitian yaitu penelitian ini menggunakan literature review, dalam pencarian literatur bersumber dari 2 database (Pubmed dan Google Scholar) menggunakan kata kunci sesuai dengan tema. Berbeda dengan penelitian sebelumnya, pada penelitian ini berfokus pada penggunaan obat antidiabetes pada penyakit nefropati diabetik. Adapun jumlah literatur yang digunakan yaitu sebanyak 3 artikel jurnal. Dimana hasil yang didapatkan bahwa penggunaan obat antidibetes pada penyakit nefropati diabetik yang paling efektif yaitu kombinasi antara AOD dengan insulin seperti obat antidiabetes metformin dengan insulin insulin long-acting (kerja panjang) atau atau rapid-acting (kerja cepat).
LITERATURE REVIEW: PENGGUNAAN OBAT ANTIBIOTIK PADA PASIEN PNEUMONIA Dewi Yuliana; Miftahul Janna A
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 1 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Pneumonia is an acute inflammatory disease of the lung parenchyma which usually results from an acute lower respiratory tract infection with coughing and shortness of breath. The purpose of this study was to find out how to use antibiotics in pneumonia patients. The research method is that this study uses literature reviews, in searching literature sourced from 2 databases (Pubmed and Google Scholar) using keywords according to the theme. Unlike previous studies, this study focuses on the use of antibiotic drugs in pneumonia patients. The amount of literature used is 13 journal articles
POLA PENGGUNAAN ANTIBIOTIK PADA PASIEN TUBERKULOSIS DI PUSKESMAS PEKKAE KABUPATEN BARRU SULAWESI SELATAN PERIODE JANUARI – DESEMBER 2022 Dewi Yuliana; Bayu Putra; Andi Ahmad Syahrul
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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ANDI AHMAD SYAHRUL, This study aims to determine the pattern of antibiotic use in tuberculosis patients at the Pekkae Health Center, Barru in 2022. The method used is an observation method using a sampling technique, namely total sampling. The results showed that the dominant male patients were 59.1%; aged 45-54 and 55-64 as much as 22.72%. The use of drugs was adjusted to the patient's weight with intensive phase treatment of 3 2KDT tablets which was 50% then 4 4KDT tablets and 4 2KDT tables which were 27.27% then 3 4KDT tablets and 4 2KDT tablets which were 13.63% and 2 4KDT tablets and 2 2KDT tablets as much as 9.1%. The conclusion in this study is that the use and suitability of OAT is based on the TB control guidelines of the Indonesian Ministry of Health in 2016, which was used in 3 patients who had an increase in the number of tablets taken in combination doses and 1 patient there was a decrease in the number of tablets taken in combination doses and the pattern of using drugs with a fixed dose combination containing rifampicin 150 mg, isoniazid 75 mg, pyrazinamide 400mg, ethambutol 275 mg
A LITERATUR REVIEW : AKTIVITAS IMUNOMODULATOR PADA TANAMAN HERBAL Dewi Yuliana; Dian Pratiwi Handayani; Vina Purnamasari
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 4 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

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Abstract

Health problems that often occur in Indonesia are problems related to diseases caused by free radicals. The presence of free radicals can trigger damage to cells and can disrupt the body's immune system. The immune system can be enhanced or suppressed, one way is by administering immunomodulators. Several natural compounds have the ability to increase immune system activity, including flavonoids, curcumin, limonoids, vitamin C, vitamin E and catechins. Phenolic components such as flavonoids and polyphenols can improve the immune system by increasing Interleukin-12 (IL-12) and lymphocyte proliferation. Based on the many health problems that arise in Indonesia due to the presence of free radicals, the aim of the research is to conduct a literature review on the mechanism of action of herbal plants as immunomodulators and the methods used to determine the mechanism of action of natural immunomodulators. The method used to review this article is to carry out an online search process using several search engines such as PubMed, Scopus, ProQuest and Schoolar. Based on reference studies, several herbal plant extracts act as immunomodulators with different activities such as increasing the activity of Immunoglobulin M (IgM), reducing the number of leukocytes, stimulating the body's immunity with flavonoid content and increasing the ability of phagocytosis.
PENGARUH POSITIONING MODIFIKASI NESTING TERHADAP PERUBAHAN TANDA VITAL BAYI PREMATUR: Efektivitas pemberian positioning modifikasi nesting terhadap tanda vital bayi premature Winda Sefrina Hutasoit; Dewi Yuliana
Jurnal Vokasi Keperawatan (JVK) Vol. 8 No. 1 (2025): JUNI
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/jvk.v8i1.41943

Abstract

Mengurangi angka kematian bayi prematur menjadi salah satu indikator kemajuan kesehatan Indonesia. Berdasarkan hasil pra survey yang dilakukan di ruang NICU RSUD DR H Abdul Moelok Provinsi Lampung, angka kematian bayi prematur pada bulan Oktober - Desember 2024 sebanyak 17 bayi. Penelitian ini ingin mengetahui pengaruh pemberian positioning modifikasi nesting kepada bayi prematur sebagai salah satu tindakan developmental care pada bayi prematur terhadap perubahan tanda vital. Pemberian positioning pada penelitian ini terbukti memberikan pengaruh pada perubahan tanda vital. Penelitian ini menggunakan metode pre post test desaign quasi eksperimen, dimana ada 20 bayi premature yang di ambil sebagai sampel, kemudian bayi diberikan 4 perubahan posisi yaitu prone, quarter prone, supine, lateral selama 3 - 6 jam, kemudian tanda vital ditulis di lembar observasi. Penelitian ini menggunakan analisa Wilcoxon signed ranks test. dengan nilai Asyms sig 0,00 maka didapatkan kesimpulan ada perubahan pada tanda vital saat melakukan positioning modifikasi nesting. Kata kunci : positioning, premature, tanda vital
Analisis Kebugaran Jasmani Siswa Melalui Tes Lari 1000 Meter Siswa Kelas 5 SDN Pojok 2 Kota Kediri Dewi Yuliana; Mohammad Nur Kholis; Ahmad Zakiyyunnuhaa
JOURNAL SAINS STUDENT RESEARCH Vol. 3 No. 3 (2025): Jurnal Sains Student Research (JSSR) JUNI
Publisher : CV. KAMPUS AKADEMIK PUBLISING

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61722/jssr.v3i3.4678

Abstract

This study aims to determine the physical fitness level of fifth-grade students at SDN Pojok 2 Kota Kediri through a 1000-meter running test. A descriptive quantitative approach was used with a total sample of 30 students, consisting of 17 boys and 13 girls. The results showed that most students fell into the "poor" and "very poor" fitness categories. Male students were mostly in the "poor" category (47.1%) with an average time of 6.21 minutes, while female students were predominantly in the "very poor" category (76.9%) with an average time of 10.2 minutes. Only a few students reached the "fair" and "good" categories, and none achieved the "very good" category. These findings indicate that students’ physical fitness, especially cardiovascular endurance, is still low. Therefore, a structured, enjoyable, and inclusive fitness program is necessary to enhance student participation, particularly among girls. This study is expected to serve as a reference for PE teachers and schools in designing effective and sustainable strategies to improve students’ physical fitness.
Co-Authors Achsien Hidajat Ahmad Zakiyyunnuhaa Aminah Aminah Andi Ahmad Syahrul Andi Emelda Andi Khuswatun Khazanah Ishak Andi Maulana Lolo Athifah Athifah Ayu Anggraini Bayu Putra Dian Pratiwi Handayani hernida hernida Ida Ayu Putu Sri Widnyani Lithrone Laricha Salomon Mahyudi, Johan Miftahul Janna A Mohammad Nur Kholis Novisita Ratu novita annur ramadhani Putri Hardiyanti Ratu Betta Rudibiyani Rika Febriani, Rika Saryatmo, Mohammad Agung Syahrul Qodri Syaipul Bahri Tasviri Efkar Vina Purnamasari Winda Sefrina Hutasoit Wulan Wulan