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All Journal HAYATI Journal of Biosciences Natural Science: Journal of Science and Technology AL KAUNIYAH Majalah Kedokteran Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmamedika (Pharmamedica Journal) JIIP (Jurnal Ilmiah Ilmu Pendidikan) Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Journal of Arabic Language and Literature Studies Rumphius Pattimura Biological Journal
Muhammad Alfarabi
Departemen Biokimia, Fakultas Kedokteran Universitas Kristen Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Internalization of Multicultural Islamic Education Values to Students in Junior High Schools (SMP) in Hinai Langkat District Hanum, Aziza; Alfarabi, Muhammad; Firmansyah, Feri
Budapest International Research and Critics Institute-Journal (BIRCI-Journal) Vol 5, No 4 (2022): Budapest International Research and Critics Institute November
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v5i4.7343

Abstract

The aims of this study is to find out the Internalization of Multicultural Islamic Education Values to Students in Junior High Schools (SMP) In Hinai Langkat District. This study uses qualitative research. The result of this study shows that the programs for junior high schools (SMP) throughout Hinai District in internalizing the values of multicultural Islamic education for students are the application of multicultural Islamic education values in the learning process, multicultural-based extracurricular activities at school, a multicultural school environment, and school rules and regulations that accommodate the values of differences in diversity. Furthermore, this program will be applied to school activities in implementing multicultural Islamic education for students. As for the implementation of the activities of junior high schools (SMP) throughout the Hinai sub-district in internalizing the values of multicultural Islamic education for students including teacher activities in teaching, school habituation activities, teacher exemplary behavior, school activities with historical, gender and cultural approaches and activities such as reading the Qur'an and praying before studying, praying, infaq, Ramadan activities and celebrating Islamic holidays. These activities instill the values of multicultural Islamic education so that students will become tolerant, appreciative, compassionate, and plural among fellow school members. Obstacles in applying the values of multicultural Islamic education include students' personalities and different cultures, the lack of depth in religious learning and the heterogeneous ethnic backgrounds of students. While the supporting factors in internalizing the values of multicultural Islamic education in schools include the existence of religious facilities such as prayer rooms and spaces for non-Muslim worship, the enforcement of school culture that applies discipline in school rules, and school activities that apply Islamic educational values multicultural in students.
The In Vitro and In Silico Study of α-glucosidase Inhibition by Kombucha Derived from Syzygium polyanthum (Wight) Walp. Leaves Yuningtyas, Sitaresmi; Alfarabi, Muhammad; Lestari, Yunita; Noviardi, Harry
HAYATI Journal of Biosciences Vol. 31 No. 5 (2024): September 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.5.951-963

Abstract

Kombucha is a fermented tea drink using a symbiotic culture of bacteria and yeast. This drink has been widely used to maintain blood sugar levels. Meanwhile, leaf boiled water of Syzygium polyanthum (Wight) Walp. has been used as an alternative medicine for diabetes mellitus in Indonesia. If this herb is made into kombucha, it may have higher antihyperglycemic activity than kombucha from tea leaves. However, there are no scientific reports of antihyperglycemic activity from S. polyanthum leaf kombucha by inhibiting alpha-glucosidase. This study aims to determine the activity and kinetics inhibition of S. polyanthum leaves kombucha against α-glucosidase. Samples were prepared at varying concentrations (12.5, 25, 37.5, 50 g/L), while phytochemical components in the products were identified, and the inhibitory activity as well as kinetics were comprehensively analyzed. In silico evaluations were conducted to further explore the inhibitory activity. The results showed that the products contained secondary metabolites such as flavonoids, saponins, and tannins. The inhibitory activity against α-glucosidase ranged from 81.05 to 89.41%. The inhibition mechanism was identified as uncompetitive, with a Michaelis-Menten constant (KM) of 0.1357 mM and a vmax value of 27.7008 U/ml minute. Several metabolites showed promising inhibition potential due to their strong binding interactions with α-glucosidase, including hydrogen bonding (H-bond), hydrophobic interactions, van der Waals forces, and electrostatic forces. Additionally, two metabolites, farnesol and α-pinene, were found to interact with other human proteins. These observations showed the potential of S. polyanthum leaves kombucha as a health-promoting beverage that might aid blood sugar control in diabetic individuals.
SPEECH ACTS ANALYSIS IN POSTS OF AL-JAZEERA'S ARABIC INSTAGRAM PAGE: تحليل أفعال الكلام في منشورات الصفحة العربية لقناة الجزيرة على منصة الإنستغرام Alfarabi, Muhammad; Sudiarti, Sri; Mahendra, Ahdiyat
Journal of Arabic Language and Literature (ALLAIS) Vol. 4 No. 1 (2025)
Publisher : Universitas Islam Negeri Raden Mas Said Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22515/allais.v4i1.12174

Abstract

This study investigates the use of speech acts in digital news discourse through an analytical examination of selected posts from the Arabic-language Instagram page of Al-Jazeera. Drawing on the theoretical framework of speech act theory as developed by Austin (1962) and Searle (1969), the research aims to identify the types and pragmatic functions of speech acts employed in visual-verbal posts related to political and social events. Using a descriptive-analytical method and qualitative content analysis, this study reveals that Al-Jazeera's Instagram posts do not merely perform an informative function; rather, they utilize a variety of speech act types—including assertives, directives, expressives, commissives, and declaratives—to construct meaning, influence perception, and guide public sentiment. The analysis highlights the strategic deployment of language in digital Arabic media to serve communicative intentions beyond mere news reporting. These findings contribute to a deeper understanding of how language operates as a pragmatic tool in shaping digital public discourse within Arabic media contexts.
ANALISIS ANTIOKSIDAN TANAMAN PETAI (PARKIA SPECIOSA) SECARA IN VITRO DAN IN SILICO Mai Cing, Jap; Alfarabi, Muhammad; Suryani Arodes, Evy
Jurnal Farmamedika (Pharmamedika Journal) Vol 10 No 1 (2025): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v10i1.465

Abstract

Pangan fungsional merupakan makanan yang memiliki khasiat kesehatan dan aman dikonsumsi secara berkelanjutan dan biasanya berasal dari makanan yang dikonsumsi sehari-hari. Petai (Parkia speciosa) merupakan pangan yang banyak menjadi masakan di daerah Indonesia. Biji petai merupakan bagian yang banyak dikaji efek kesehatannya. Namun, tidak banyak laporan ilmiah yang mengkaji mengenai bioaktivitas bagian lain dari tanaman petai. Tujuan dari penelitian ini adalah untuk mengukur dan membandingkan aktivitas antioksidan dari biji, batang, daun, dan kulit polong biji petai. Aktivitas tersebut dilakukan dengan metode DPPH (2,2-diphenyl-1-picrylhydrazyl). Kajian in silico juga dilakukan sebagai pendekatan lebih lanjut terhadap aktivitas antioksidannya. Hasil menunjukkan bahwa esktrak dari biji, batang, daun, dan kulit polong biji petai memiliki aktivitas antioksidan dengan kemampuannya menghambat radikal bebas. Aktivitas hambatan ini bernilai 53-68% untuk biji, 74-88% untuk batang, 54-80% untuk daun, dan 73-82% untuk kulit polong biji petai. Hasil analisis in silico menunjukkan bahwa kandungan metabolit dari petai yang berpotensi sebagai agen pereduksi radikal bebas adalah quercetin. Metabolit ini mampu berinteraksi kuat dengan enzim mieloperoksidase. Oleh karenanya, penelitian ini bermanfaat sebagai informasi ilmiah untuk pengembangan pangan fungsional berbasis petai sebagai antioksidan.
In Vitro and In Silico Evaluation of Antioxidant Activity of Muscle and Endoskeleton from Sepia officinalis Daniella, Katherine; Ismail, Rafly Alif; Fahrudin, Fahri; Cing, Jap Mai; Alfarabi, Muhammad
RUMPHIUS Vol 7 No 2 (2025): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv7i2p128-137

Abstract

Sepia officinalis, commonly known as cuttlefish, is one of the diverse marine organisms consumed for its high protein content. Amino acids, as the building blocks of proteins, can function as antioxidant compounds. The high amino acid content in cuttlefish makes it a potential natural source of antioxidants. However, the use of cuttlefish in medicine, particularly as an antioxidant source, remains limited in Indonesia. At present, cuttlefish is mainly utilized as a dietary protein source. The objective of this study was to evaluate the antioxidant activity of muscle and endoskeleton extracts from S. officinalis using the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay in vitro. In addition, an in silico approach was employed to analyze the interaction of these extracts with myeloperoxidase, an oxidant-producing enzyme. The results demonstrated that both muscle and endoskeleton extracts were able to scavenge free radicals, showing DPPH inhibition ranging from 46.19% to 48.42%. The highest inhibition was observed at a concentration of 200 ppm for both extracts. Furthermore, in silico analysis revealed that tyrosine and phenylalanine were the key amino acids with antioxidant potential, as they inhibited myeloperoxidase activity and could reduce oxidant production by the enzyme. These findings highlight the potential of S. officinalis as a natural antioxidant source and support its future development as a functional food ingredient.
Co-Authors CHAIDIR CHAIDIR Cing, Jap Mai Daniella, Katherine Daulay, Annisa Arummaisyah Dena Carolina Sabono Evilin E. Yuniarti Fahri Fahrudin, Fahri Fauziayuningtias, Atikah Feri Firmansyah, Feri Forman Erwin Siagian Fuad, Phil Zainul Gupita Widyadhari Hanum, Aziza Harry Noviardi Ismail, Rafly Alif Khalidi, Nasrun Khanza Othadinar Koto, Taufiq Ismail Lestari, Yunita Mahendra, Ahdiyat Mai Cing, Jap MARIA BINTANG Miftahudin . Muhammad Putra Dinata Saragi Rahman, Surya Sahputra, Dika SISWA SETYAHADI Sitaresmi Yuningtyas sri sudiarti Suryani Arodes, Evy Sylvia M. Triani Viola Maharani