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Upaya Meningkatkan Sistem Kekebalan Tubuh Anak Usia Sekolah di Masa Pandemi COVID-19 Salim, Hotimah Masdan; Bintarti, Tri Wahyuni; Fitriyah, Fifi Khoirul; Alam, Ilham Putra; Muhammada, Davida Sajid; Nisaussholihah, Nadia
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol 6, No 2 (2021): May 2021
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v6i2.5001

Abstract

COVID-19 is a SARS virus infection that has spread throughout the world including in Indonesia. The existence of this pandemic has a significant impact on all countries, such as health, economy, education, and all supporting sectors of a country. In Indonesia itself adapting the New Normal to deal with this global pandemic. New Normal is associated with new habit changes that also impact the health level of children. So, the purpose of community service (PKM) is to provide education as an effort to increase the child's immune system in the face of the COVID-19 pandemic. This PKM is implemented at the Baca Rumah Kita Foundation in the Mejoyo Tenggilis sub-district. This PKM is carried out by presenting counseling to school-age children with interactive methods and games as well as health checks as screening and providing supplements to improve the child's immune system. Based on the PKM results, it was found that the children were enthusiastic about this activity. From the results of health screening, participants aged 5-10 years were 84.21%. With a nutritional status of 47.37% less, 15.79% less nutrition, 26.32% good nutrition, and 10.53% over nutrition. Based on the results of this screening, it can be used as a measure that the growth and development of children in this region needs special attention, especially during the current pandemic.DOI: https://doi.org/10.26905/abdimas.v6i2.5001
THE RELATIONSHIP OF NUTRITIONAL STATUS TO URIC ACID LEVEL IN COMMUNITY OF PONDOK PESANTREN AL-HIDAYAH, NGAWI Lestari, Marselli Widya; Bintarti, Tri Wahyuni
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i1.925

Abstract

Gout or Gouty Arthritis is a degenerative disease. Gouty arthritis is a clinical syndrome that is caused by deposition of purine crystals in the tissues, due to levels of uric acid (hyperuricemia) in the extracellular fluid that passes through saturation. The etiology of gout arthritis included age, sex, history of medication, obesity, consumption of purine and alcohol. Aging is an important risk factor for men and women. This study uses an analytical-descriptive approach with cross-sectional design. This study was conducted to obtain a relationship between nutritional status and uric acid levels in the community in the area of Al-Hidayah Islamic Boarding School, Ngawi. This research was conducted in Majasem Village, Kendal District, Ngawi Regency, starting from 7 June - 31 August 2018. The results showed that there was a relationship between nutritional status and uric acid levels in the community in the area of Al-Hidayah Islamic Boarding School, Ngawi (p=0,008). Suggestions for further research are bivariate analysis based on gender, knowledge and attitude to response to diet so that other factors that influence can be seen clearly.
EDUKASI PENGOLAHAN BAWANG PUTIH PADA MENU SANTRI SEBAGAI ANTIOKSIDAN DAN ANTI KANKER Veterini, Lysa; Bintarti, Tri Wahyuni; Wulandari, Devyana Dyah; Alkatiri, Wardah
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 6 (2023): Volume 4 Nomor 6 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i6.22723

Abstract

Latar belakang: Aktivitas santri yang begitu padat setiap harinya, maka dibutuhkan kondisi yang fit agar dapat menjalani kegiatan pembelajaran di Pondok Pesantren dengan baik. Senyawa yang mengandung antioksidan dibutuhkan untuk melawan radikal bebas yang masuk ke dalam tubuh. Tujuan kegiatan pengabdian kepada masyarakat ini adalah untuk meningkatkan pengetahuan para santri PP. KHA Wahid Hasyim Bangil Pasuruan mengenai manfaat bawang putih bagi kesehatan serta cara pengolahannya untuk mendapatkan efek antioksidan dan antikanker yang tentunya berguna bagi kesehatan santri. Metode: Kegiatan pengabdian kepada masyarakat ini dilakukan dengan metode presentasi. Rangkaian kegiatan pengabdian kepada masyarakat ini dimulai dari sesi persiapan yaitu pembuatan materi, pembuatan soal pre dan post-test, dan persiapan dokumen maupun administrasi lain. Soal Pre-test dan post-test diberikan kepada peserta digunakan sebagai indikator tingkat pengetahuan peserta sebelum dan sesudah diberikan materi. Hasil dan pembahasan: Hasil rata-rata nilai pre-test adalah 82, sedangkan nilai rata-rata post-test adalah 89. Hal ini menunjukkan terdapat peningkatan rata-rata nilai sebesar 7% dari sebelum diberikan materi (pre-test) dengan setelah diberikan materi (post-test). Terdapat peningkatan pengetahuan santri mengenai manfaat bawang putih bagi kesehatan serta cara pengolahannya untuk mendapatkan efek antioksidan dan antikanker yang tentunya berguna bagi kesehatan santri. Kesimpulan: Kegiatan pengabdian kepada masyarakat ini telah terlaksana dengan baik. Semua peserta hadir dan mengikuti acara dari awal hingga akhir, serta sangat antusias termasuk dalam sesi diskusi. Hasil akhir kegiatan pengabdian kepada masyarakat ini adalah terdapat peningkatan pengetahuan para peserta pengabdian kepada masyarakat yakni santri PP. KHA Wahid Hasyim Bangil Pasuruan.
SKRINING KADAR KOLESTEROL DAN IMT PADA PENGURUS PONDOK PESANTREN HIDAYATULLAH AL MUHAJIRIN BANGKALAN MADURA Bintarti, Tri Wahyuni; Sari, Paramita; Awwalia, Evi Sylvia; Choirotussanijjah, Choirotussanijjah
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 6 (2023): Volume 4 Nomor 6 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i6.23685

Abstract

Kadar Kolesterol dalam darah yang tinggi dapat menyebabkan plag disekitar dinding pembuluh darah. Peningkatan kadar kolesterol sering dihubungkan dengan Indeks Massa Tubuh. Sehingga deteksi dini mengenai kadar kolesterol dalam darah dan status gizi berdasarkan IMT diperlukan. Pada kegiatan ini dilakukan studi & edukasi tentang kadar kolesterol dan IMT pada warga atau pengurus pondok pesantren Hidayatullah Al Muharijin Bangkalan Madura. Pelaksanaan kegiatan dilakukan dengan beberapa tahap yaitu persiapan, pelaksanaan, evaluasi dan pelaporan. Kegiatan ini diikuti oleh 55 responden yang terdiri dari 8 laki laki (15%) dan 47 perempuan (85%) dengan rentang usia terbanyak adalah masa remaja akhir (17-25 tahun) 47%, masa dewasa awal (26-35 tahun) 25% serta masa dewasa akhir (36-45 tahun) 15%. Status gizi responden lebih dari normal adalah obese I yaitu 30,9%, overweight at risk yaitu 20% dan obese II yaitu 18,2%. Sedangkan status gizi normal range (21,8%) dan underweight (9,1%). Hasil pemeriksaan kadar kolesterol pada kegiatan ini paling banyak adalah kadar normal yaitu 63,6%, kemudian kadar kolesterol di ambang tinggi sebanyak 23,63% serta kadar kolesterol tinggi sekitar 12,72%. Hasil pemeriksaan menunjukkan bahwa kadar kolesterol total dalam darah tidak selalu dipengaruhi oleh jenis kelamin, usia serta IMT berlebih. Namun perlu adanya studi khusus tentang keterkaitan kadar kolesterol dan beberapa faktor yang menjadi pengaruhnya. Selain mendapatkan skrining pemeriksaan kadar kolesterol dalam darah, para responden juga mendapatkan fasilitas konsultasi kesehatan dan pengobatan.
The Effect of Honey Administration on The Histopathology of The Duodenum of Wistar Rats as a Inhibition of The Toxic Effects of Borax (Sodium tetraborate) Noviana, Dian; Syarifah, Mustika Chasanatusy; Gumilang, Retna; Bintarti, Tri Wahyuni
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4445

Abstract

Background: Borax can result in oxidative stress and cause the onset of gastrointestinal ulcerations that will dampen the duodenal villi to become shorter and can even disappear. Cell damage due to oxidative stress can be prevented by administering antioxidants. Antioxidants will inhibit the onset of chain reactions in the formation of free radicals by complementing the existing electron deficiency. Honey is one of the natural ingredients that is rich in antioxidants and part of thibbun Nabawi as one of the inhibitors of the toxic effects of borax. Objective : The purpose of this study is to to analyze the effect of honey administration on the histopathological description of submucosa and epithelial mucosa of duodenal wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate). Methods: This study used the true experimental method with Post Test Only Control Group Design using 25 mice which will be divided into five groups, namely K (negative control), P (positive control), M1 (borax and honey dose 1), M2 (borax and honey dose 2), M3 (borax and honey dose 3). This study was conducted for 22 days then. Took the duodenal organ on all samples and then made histological preparations with HE staining. Observations were made with an Olympus microscope to see submucosal edema and damage to the epithelium of the duodenal mucosa. Results: The results of the study found that borax 26 mg / head / day had an influence on the histopathological picture of duodenal borax. In addition, the administration of honey dose 75 mg / Kg BB provides a toxic inhibitory effect of borax in the duodenum best among other treatment groups. However, statistically there was no effect of honey administration on the histopathological picture of the duodenum of wistar rats as an inhibitor of the toxic effect of borax (Sodium Tetraborate) with p˃0.05. Conclusion: Statistically it can be concluded that there is no effect of  the administration of honey on the histopathology picture of the duodenum of wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate).
Effect of Oral Administration of Mytragina Speciosa on Blood Ketone Level and Glomerular Histology in Streptozotocin Induced Diabetic Mice choirotussanijjah, Choirotussanijjah; Salim, Hotimah Masdan; Bintarti, Tri Wahyuni; Irawan, Danny
Jurnal Medis Islam Internasional Vol 6 No 1 (2024): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v6i1.5232

Abstract

Introduction: Diabetes mellitus is a chronic metabolic disease characterized by increased sugar levels that cause serious damage to various organs. Diabetic ketoacidosis is one of the complications of diabetes mellitus. It is characterized by a decrease in the patient's consciousness, increased blood sugar levels, and the presence of acidic ketone bodies. It is a serious condition that can cause a coma or even death. Mytragina Speciosa,  known as kratom, is a plant often found in Southeast Asia, including Indonesia. This herb is frequently used as a stimulant to treat fatigue and help improve productivity. Based on previous research, Mytragina Speciosa is rich in alkaloids, flavonoids, and phenols. These compounds are very useful for inhibiting the activity of α-glucosidase and lipase enzymes in the pancreas, so they have a potential effect on diabetes mellitus. However, there has been no research related to the administration of Mytragina Speciosa its effect on blood ketone levels and glomerular diameter. Objective: to determine whether there is an effect of Mytragina Speciosa on blood ketone levels and glomerular diameter in mice with a diabetes mellitus model. Methods: Hyperglycemia is induced by Streptozotocin. On the 14th day, the mice will be checked for hyperglycemia and blood ketone levels. Administration of Mytragina Speciosa begins on day 15 for 2 weeks. At the end of the second week, the mice will be checked for blood ketone levels using a special kit to detect ketone bodies. Furthermore, the glomerular diameter will also be assessed. Results: In this study, treatment for 2 weeks only caused an increase in blood sugar levels in mice, but did not cause an increase in blood ketone levels in the diabetes group or other treatment groups (p > 0.05). Histological preparation of the Glomerulus showed a decline in glomerular diameter. Conclusions: The administration of Mitragyna speciosa extract did not result in a significant increase in blood ketone levels in diabetic mice. Many factors are involved in increasing blood ketone. It is necessary to monitor ketone levels during treatment as well as have a longer treatment time to see the effect of Mitragyna speciosa on ketones
Edukasi Sindroma Metabolik dan PCOS Pada Remaja Perempuan di PP KHA Wahid Hasyim Awwalia, Evi Sylvia; Bintarti, Tri Wahyuni; Azzuhri, Salvia Adzania Widya; Prawidya, Syahrul Gusnaldi; Bariyah, Khadijah Khairul
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 11 (2024): SWARNA: Jurnal Pengabdian Kepada Masyarakat, November 2024
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pertumbuhan remaja menjadi sebuah periode yang menentukan karena berkaitan dengan perkembangan organ tubuh dan sistem hormonal. Remaja perempuan cenderung terpapar pada berbagai faktor risiko, termasuk karena kebiasaan makan yang tidak sehat dan kurangnya aktivitas fisik sehingga dapat menjadi pemicu potensial untuk sindroma metabolik dan Polycystic Ovary Syndrome (PCOS). Dengan memberikan edukasi yang menyeluruh mengenai sindroma metabolik dan PCOS, dapat membantu remaja perempuan memahami pentingnya menjaga kesehatan selama masa pertumbuhan mereka. Tujuan kegiatan ini yaitu meningkatkan wawasan santriwati tentang PCOS dan Sindroma Metabolik pada Remaja Perempuan serta cara penanganannya apabila ada santri yang mengalami dua hal tersebut. Metode yang diterapkan dengan memberikan materi penyuluhan kepada mitra 40 santriwati PP. Putri KHA. Wahid Hasyim Bangil. Sebelum pemberian materi penyuluhan, dilakukan pemberian kuesioner pre test selama 5 menit untuk para peserta, dilanjutkan pemberian materi PCOS dan Sindroma Metabolik serta tanya jawab selama 45 menit, setelahnya dilakukan pemberian kuesioner post test selama 5 menit. Hasil pre dan post-test dinilai, diolah data, serta dievaluasi oleh tim penyuluhan. Hasil kuesioner pre dan post test dengan topik PCOS dan Sindroma Metabolik pada Remaja Perempuan menunjukkan peningkatan pada hasil kuesioner post test. Sehingga dapat diartikan adanya peningkatan pemahaman dan perubahan sikap terhadap para peserta setelah mengikuti penyuluhan.
Model Eksperimental Diabetes Melitus Tipe 2 pada Tikus Wistar : Kombinasi Diet Tinggi Lemak, Garam, Fruktosa dan Induksi Streptozotocin Farikhah, Zumrotul; Savitri, Ardyarini Dyah; Bintarti, Tri Wahyuni; Veterini, Lysa; Wijaya, Afira Febriani Surya
Jurnal Ners Vol. 9 No. 3 (2025): JULI
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i3.48318

Abstract

Diabetes melitus tipe 2 (DMT2) merupakan masalah kesehatan global dengan patogenesis kompleks melibatkan resistensi insulin dan disfungsi sel beta. Model hewan yang relevan diperlukan untuk mempelajari mekanisme penyakit dan pengujian terapi. Mengembangkan model DMT2 pada tikus Wistar dengan menggunakan kombinasi diet tinggi lemak-fruktosa-garam dan streptozotocin (STZ) dosis rendah untuk meniru manifestasi klinis dan komplikasi DMT2 pada manusia. Lima ekor tikus Wistar jantan diberi diet tinggi lemak (30%), fruktosa (30%), dan garam (1%) selama 4 minggu, dilanjutkan injeksi STZ (35 mg/kgBB). Parameter yang diukur meliputi kadar glukosa darah puasa, berat badan, serta analisis histopatologi pankreas dan ginjal. Peningkatan signifikan kadar glukosa darah (median: 497 mg/dL) dan penurunan berat badan (21 gram) diamati setelah intervensi. Histopatologi menunjukkan insulitis dengan derajat bervariasi (Score 2: 30% sampel; Score 1: 5% sampel) dan kerusakan tubulus ginjal ringan. Kombinasi diet obesogenik dan STZ berhasil menginduksi hiperglikemia persisten serta perubahan histopatologis yang menyerupai DMT2 manusia. Model ini potensial untuk studi patogenesis dan terapi DMT2, meskipun perlu optimasi untuk mengurangi variabilitas respons.
Effects of Kratom (Mitragyna speciosa) Hydrogel Application on Pancreatic Histopathology in Type 2 Diabetic Mice Muhammad Aqil Siroj Jazuli; Ismail, Zainul Hadi Wildan; Rihhadatulays, Khuzaimah Nur Juhanifah; Hanafi, Eka Satria Akbar Ferdinan; Jinan, Puspita Rahmatul; Pramesti, Rosandhy Alifyah; Salim, Hotimah Masdan; Bintarti, Tri Wahyuni
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.8018

Abstract

Background: Type 2 diabetes mellitus is a metabolic disorder characterized by elevated blood glucose caused by insulin resistance and impaired insulin production by pancreatic β-cells due to oxidative stress. Kratom (Mitragyna speciosa) has been widely investigated for its antidiabetic, anti-inflammatory, and antioxidant effects, attributed to its alkaloid, flavonoid, phenolic, and saponin contents. This study aimed to evaluate the potential of topical kratom hydrogel as an innovative approach to improving pancreatic histology in type 2 diabetic mice, which has not been previously reported. Methods: Fifteen mice were divided into three groups: untreated diabetic group (DM), diabetic group treated with 5% kratom hydrogel (K5), and diabetic group treated with 15% kratom hydrogel (K15). Treatments were administered for two weeks. Parameters assessed included the percentage of healthy β-cells and acinar cells, as well as histological scoring of islet damage. Data were analyzed using parametric or non-parametric tests according to the normality distribution of each parameter. Results: Administration of 5% kratom hydrogel significantly increased the percentage of healthy β-cells (p<0.05) compared with 15% kratom hydrogel, which unexpectedly showed a lower proportion of healthy cells than the untreated group. Interestingly, the higher dose appeared to exert more toxic effects, whereas the lower dose provided better protective effects. No significant differences were observed in acinar cell parameters or islet damage scores, possibly due to the limited sample size. Conclusion: These findings provide preliminary evidence supporting the systemic therapeutic potential of topical kratom hydrogel, particularly in determining the effective dose and the need for larger sample sizes to obtain more consistent outcomes.