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All Journal E-Jurnal Medika Udayana Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Menara Medika Jurnal Muara Medika dan Psikologi Klinis
Trinovita Andraini
Department of Physiology Faculty of Medicine Universitas Indonesia, Jakarta
Health Professions Medicine & Pharmacology Neuroscience Public Health

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HIBISCUS SABDARIFFA LINN. MENCEGAH PENURUNAN FUNGSI MEMORI KERJA PADA MENCIT MODEL DIABETES TIPE 2 Anggraeni, Risa Kusuma; Andraini, Trinovita
E-Jurnal Medika Udayana Vol 11 No 12 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i12.P07

Abstract

Diabetes mellitus (DM) is a risk factor for memory impairment. Administration of herbal medicine which is rich in polyphenol has been believed have a positive impact on memory performance. Recent studies showed one of the potential candidates of herbal medicine is Hibiscus sabdariffa Linn. (HSL) which can improve memory function in several conditions. However, researches which prove will HSL affect memory function in DM is still limited. The aim of the study is to investigate the effect of HSL administrating on spatial working memory in DM. This study is an experimental study using DDY mice aged 9-11 weeks which were divided into four groups: control (K), DM control (DM), DM with HSL at a dose of 200 mg/kgBW (DM-HSL200), and DM with HSL at a dose of 400 mg/kgBW (DM-HSL400). Experimental animals were given treatment for 28 days. All groups performed Y- Maze spontaneous alternation before and after treatment. The results of this study showed a decrease in memory function in the DM group. Administration of HSL can maintain memory function in DM mice. These findings indicate that administration of HSL has potency to prevent memory impairment in DM. Keywords : Hibiscus sabdariffa Linn., spatial working memory, diabetes mellitus, Y-maze spontaneous alternation.
THE EFFECT OF TAHAJUD PRAYER ON STRESS Pranata, Lilik; Irfannuddin, Irfannuddin; Ali, Zulkhair; Andraini, Trinovita
Menara Medika Vol 7, No 2 (2025): VOL 7 NO 2 MARET 2025
Publisher : Fakultas Kesehatan Universitas Muhammadiyah Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/mm.v7i2.6951

Abstract

Introduction: Stress is a physical and emotional reaction that occurs when a person faces pressure or environmental changes that require them to adapt. If stress is left unchecked, it can lead to many disorders. One thing that can be done is to perform tahajud prayers. The purpose of this study is to determine the benefits of tahajud prayer on stress. Method: The research design uses a literature review method by analysing articles from databases such as PubMed, Science Direct, ProQuest, and Google Scholar, focusing on articles published between 2020 and 2025, using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart approach. After selection, six articles were found to meet the inclusion criteria. Results: Tahajud prayer therapy can reduce stress levels. Discussion: Every individual experiences different levels of stress, so the process of performing tahajud prayer must be adapted to the stress level. The activity of tahajud prayer should be performed regularly without coercion and with sincerity.
KUALITAS TIDUR PADA BAYI USIA 6-9 BULAN DI JAKARTA Herwanto, Herwanto; Sekartini, Rini; Batubara, Jose; Yusra; Kekalih, Aria; Lestari, Hesti; Andraini, Trinovita
Jurnal Muara Medika dan Psikologi Klinis Vol. 5 No. 1 (2025): Jurnal Muara Medika dan Psikologi Klinis
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jmmpk.v5i1.35276

Abstract

Gangguan tidur dapat memengaruhi kondisi kesehatan seorang bayi. Penelitian ini bertujuan menganalisis faktor yang memengaruhi kualitas tidur bayi usia 6-9 bulan di Jakarta dengan menggunakan kuesioner Brief Infant Sleep Questionnaire-Revised (BISQ-R). Penelitian ini menggunakan desain studi potong lintang dengan pendekatan deskriptif analitik, data didapatkan melalui kuesioner BISQ-R untuk menilai kualitas tidur bayi berdasarkan pola tidur bayi, persepsi orang tua, dan kebiasaan pada orang tua yang terkait dengan tidur pada Bayi. Data dianalisis untuk mengidentifikasi faktor yang memengaruhi kualitas tidur bayi dan hubungan antar variabel. Sebanyak 88 subjek, yang terdiri dari 33 bayi perempuan dan 55 bayi laki-laki dengan rata-rata usia 7,76 bulan, terlibat dalam penelitian ini. Hasil penelitian menunjukkan mayoritas bayi memiliki kualitas tidur yang tergolong menengah serta menunjukkan bahwa faktor "jumlah waktu terbangun di malam hari" memiliki korelasi negatif yang signifikan terhadap kualitas tidur bayi (r = -0,258, p = 0,015), menunjukkan bahwa semakin sering bayi terbangun pada malam hari, semakin berkurang kualitas tidurnya. Kebiasaan orangtua merespons kebutuhan tidur dan tempat tidur bayi juga turut memengaruhi kualitas tidur. Penelitian ini menunjukkan pentingnya mengurangi frekuensi bayi terbangun di malam hari untuk meningkatkan kualitas tidurnya serta perlunya menjaga konsistensi rutinitas tidur dan menciptakan lingkungan tidur yang mendukung guna memastikan kualitas tidur bayi yang optimal.
Body Composition Parameters, Adiponectin, Leptin and Adiponectin/Leptin Ratio are Correlated with LH/FSH Ratio in Women with PCOS but not in Women without PCOS Gita Pratama; Wiweko, Budi; Asmarinah; Widyahening, Indah Suci; Andraini, Trinovita; Hartanto Bayuaji; Andon Hestiantoro
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 1 January 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i1.2031

Abstract

Objective: To investigate the correlation between body composition parameters, adiponectin, leptin and the adiponectin/leptin ratio and the LH/FSH ratio in women with polycystic ovary syndrome (PCOS). Methods: A cross-sectional study was conducted at Reproductive Cluster Yasmin, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, with sixty women with PCOS and sixty healthy women as controls (matched for age and BMI). Body composition parameters, including body weight, body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR), percent body fat (PBF), visceral fat area (VFA), percent subcutaneous fat (PSF) and skeletal muscle mass (SMM), were measured; levels of fasting glucose, fasting insulin, testosterone, and sex hormone binding globulin (SHBG) were measured; and homeostatic model assessment for insulin resistance (HOMA-IR) values, anti-Mullerian hormone (AMH), free androgen index (FAI), Ferriman-Gallwey (FG) score, adiponectin levels, leptin levels, adiponectin/leptin ratio, LH, FSH and LH/FSH ratio were measured. Results: Body composition parameters (body weight, BMI, WC, WHR, PBF, VFA, PSF, SMM) were not significantly different between women with PCOS and controls. Fasting insulin (P<0.05), HOMA-IR (P<0.05), AMH (P<0.01), FAI (P<0.01), FG score (P<0.01) and LH/FSH ratio (P<0.05) were higher in PCOS women. Adiponectin (P<0.01) was lower in PCOS women, while leptin and the adiponectin/leptin ratio were not significantly different between groups. Most of body composition parameters, adiponectin, leptin and adiponectin/leptin ratio were correlated with HOMA-IR in both groups. SMM was positively correlated with the LH/FSH ratio, while body weight, BMI, WC, PBF, VFA, and PSF were inversely correlated with the LH/FSH ratio in PCOS patients but not in controls. WHR was not correlated in either group. Leptin (r=-0.278; P<0.05) was negatively correlated with the LH/FSH ratio only in the PCOS group. Adiponectin (r=0.394; P<0.01) and the adiponectin/leptin ratio (r=0.413; P<0.01) were also positively correlated with the LH/FSH ratio only in the PCOS group. AMH was correlated with the LH/FSH ratio, whereas testosterone level, FAI, FG score, fasting insulin level and HOMA-IR value were not correlated with the LH/FSH ratio in PCOS women. Conclusion: Most of the body composition parameters, leptin, adiponectin and the adiponectin/leptin ratio were significantly correlated with HOMA-IR in both groups. However, correlations of those parameters with LH/FSH ratio were found only in PCOS but not in women without PCOS. Adiponectin and leptin may play a significant role in the mechanism of neuroendocrine disorders in PCOS, which is characterized by an increased LH/FSH ratio. Keywords: adiponectin, adiponectin/leptin ratio, body composition, HOMA-IR, leptin, LH/FSH ratio, PCOS
Co-Authors Andon Hestiantoro Anggraeni, Risa Kusuma Aria Kekalih Asmarinah Batubara, Jose Budi Wiweko Donna N. Kahandjak Ermita I.I. Ilyas Gita Pratama Hartanto Bayuaji Herwanto Herwanto Hesti Lestari Indah S. Widyahening Indra Kusuma Irfannuddin Irfannuddin Lilik Pranata Neng T. Kartinah Rini Sekartini Roman A. Goenarjo Sophie Yolanda Yusra Zulkhair Ali