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All Journal Jurnal Sain Veteriner Jurnal Tata Boga Journal of Artificial Intelligence and Digital Business Jurnal Kedokteran Hewan Jurnal Edukasi Sebelas April International Journal of Community Services
Devita Anggraeni
Bagian Klinik Hewan, Fakultas Kedokteran Hewan, Universitas Udayana, Bali
Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Veterinary

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MONITORING OF PHYSIOLOGICAL AND PARASITES STATUS OF BAWEAN DEER (AXIS KUHLII) IN ITS HABITAT AS A BASELINE FOR WILDLIFE CONSERVATION ENDEAVOR Nurcahyo, Wisnu; Anggraeni, Devita; Imron, M.A.
Jurnal Sain Veteriner Vol 33, No 2 (2015): Desember
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.17882

Abstract

AbstractThe research on physiological and reproduction status of Bawean deer (Axis kuhlii) in its habitat has been conducted, to understand and to find out as a basic information on Bawean deer (Axis kuhlii) in its habitats a baseline data for wildlife conservation efforts. The deer is categorized as an endangered animal, therefore, more attention was given toward Bawean deer conservation. Habitat changes, loss of habitat, fragmentation and illegal hunting might caused the wild animals become more marginalized and the populations have been declined.Therefore, it is needed to have research as an effort to save Bawean deer in its natural habitat. This research activity covered monitoring on physiological and reproduction status, and also the examination of deer's feces samples was parasite coprological data that serve as a basic consideration data in conservation and determination of Bawean deers health in the nature and/or conservation. The research was done in Bawean Island, Gresik and East Java, by taking faces of Bawean deers in the nature and conservation. Data gathering of physiological andreproduction status were done by examining deer's condition, either directly in conservation or in its habitat, and also by interviewing people around the forest. The data on physiological status, behavior monitoring, reproduction status, faces samples, blood, food analysis, and interview result were analyzed descriptively. Some worm eggs were found during feces examination, those were Strongyl, Strongyloides sp, Trichuris sp, Fasciola gigantica and Oocysta coccidia. The result showed that the same parasites were found in the cattle and goat raised by people around in the vicinity of the forest, meaning, there was an interaction between wildlife andlivestock. According to the result, it is needed to monitor the physiological status of Bawean deers routinely since Bawean deers is classified as endangered species.
PENGARUH JENIS DAN JUMLAH PUREE KACANG-KACANGAN TERHADAP SIFAT ORGANOLEPTIK DENDENG JAMUR (PLEUROTUS OSTREATUS) ANGGRAENI, DEVITA
Jurnal Tata Boga Vol 5, No 1 (2016): Volume 5 nomor 1, yudisium Februari 2016
Publisher : Jurnal Tata Boga

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Abstract

Abstrak Dendeng jamur merupakan produk olahan lauk sumber protein nabati berbentuk lempeng dengan ketebalan 3-5 mm, berasa manis dan khas bumbu dendeng. Penelitian ini bertujuan untuk mengetahui: 1) pengaruh jenis puree kacang-kacangan terhadap sifat organoleptik (warna, bentuk, aroma, rasa, tekstur, keempukan, dan tingkat kesukaan) dendeng jamur; 2) pengaruh jumlah puree kacang-kacangan terhadap sifat organoleptik dendeng jamur; 3) pengaruh interaksi jenis dan jumlah puree kacang-kacangan terhadap sifat organoleptik dendeng jamur; 4) sifat organoleptik dendeng jamur terbaik; 5) kandungan protein, lemak, karbohidrat, kalsium, zat besi, dan fosfor dendeng jamur terbaik; dan 6) harga jual dendeng jamur terbaik. Jenis penelitian ini adalah eksperimen dengan desain faktorial 3x3. Variabel bebas yaitu jenis dan jumlah puree kacang. Pengumpulan data menggunakan metode observasi melalui uji organoleptik oleh 18 panelis terlatih dan 20 panelis semi terlatih dengan instrumen lembar observasi. Analisis data menggunakan analisis varians ganda (anova) dan uji lanjut Duncan dengan bantuan SPSS 17.0. Hasil penelitian menunjukkan 1) jenis kacang-kacangan berpengaruh terhadap warna, aroma, dan rasa, tetapi tidak berpengaruh terhadap tekstur, keempukan dan kesukaan dendeng jamur; 2) jumlah puree kacang-kacangan berpengaruh terhadap warna (matang), tekstur, keempukan, dan kesukaan, tetapi tidak berpengaruh terhadap warna (kering), aroma dan rasa dendeng jamur; 3) interaksi jenis dan jumlah puree kacang-kacangan berpengaruh terhadap rasa, tetapi tidak berpengaruh terhadap warna, bentuk, aroma, tekstur, keempukan dan kesukaan dendeng jamur; 4) dendeng jamur kacang merah 15% dengan karakteristik warna (kering) coklat, bentuk bulat pipih dan sedikit nampak retak pada bagian tepi, warna (matang) coklat tua, aroma gurih khas bumbu dendeng, manis, gurih dan tidak berasa jamur tiram, tekstur cukup halus dan cukup berserat serta cukup empuk; 5) kandungan gizi dendeng jamur terbaik adalah protein 15,76%, karbohidrat 44,88%, lemak 2,05%, zat besi 0,025 ppm, kalsium 0,048 ppm, dan fosfor 0,368 ppm; 6) harga jual dendeng jamur terbaik adalah Rp. 37.000,00 per kilogram. Kata kunci : Dendeng jamur, kacang-kacangan.   Abstract Mushrooms dendeng are side dish products as vegetals protein sources shaped slabs with a thickness of 3-5mm, sweet taste and distinctive dendeng seasoning. The aims of this research are to find 1) the effect of type nuts puree of mushroom dendeng organoleptics (color, shape, aroma, flavor, texture, tenderness, and the level of preference); 2) the effect of quantity nuts puree of mushroom dendeng organoleptics; 3) the effect of interaction type and quantity nuts puree of mushroom dendeng organoleptics; 4) the best of mushroom dendeng organoleptics; 5) protein, fat, carbohydrates, calcium and phosphorus of the best mushrooms dendeng; and 6) selling price of the best mushrooms dendeng. This type of research is an experiment with a 3x3 factorial design, which were the independent variables was type and quantity of nuts puree. Collecting data using the method of observation through organoleptic test by 18 panelists trained and 20 semi-trained panelists used instrument observation sheet. Analysis of data using multiple analysis of variance (ANOVA) and Duncan advanced test using SPSS 17.0. The results of research showed that 1) type of nuts puree effected on colour, aroma, and flavour, but didn’t effect on texture, tenderness and preferences of mushrooms dendeng; 2) quantity of nuts puree effected on color (cooked), texture, tenderness, and preferences, but didn’t effect on color (dried), aroma, and flavour of mushrooms dendeng; 3) interaction type and quantity nuts puree effected on flavour, but didn’t effect on colour, shape, aroma, texture, tenderness and preferences; 4) The characteristics of mushrooms dendeng on red kidney bean 15% were color (dried) brown, flat round shape and slightly visible cracks on the edges, color (cooked) dark brown, savory aroma typical dendeng seasonings, sweet, savory and didn’t oyster mushrooms taste, texture smooth enough and sufficiently fibrous and soft enough ; 5) the nutrients of the best mushrooms dendeng were protein 15,76%, fat 2,05%, carbohydrates 44,88%, calcium 0,048 ppm, iron 0,025 ppm  and phosphorus 0,368 ppm; 6) Selling prices of the best mushrooms dendeng was Rp. 37.000,00 per kilograms. Key words: mushrooms dendeng, nuts
TINGKAT EFEKTIVITAS GLOVES STERIL INTRAOPERASI DAN PASCAOPERASI LAPAROTOMI Prastiwi, Artina; Adji, Dhirgo; Anggraeni, Devita; Purnomo, Agus; Ramadhani, Mungky Ema
Jurnal Sain Veteriner Vol 43, No 2 (2025): Agustus
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.105484

Abstract

Penggunaan glove bedah steril untuk tindakan laparotomi dilakukan untuk membatasi kontaminasi lokasi pembedahan oleh bakteri di tangan operator bedah dan dengan demikian mengurangi kemungkinan infeksi pascaoperasi. Pada prakteknya pergantian gloves steril selama proses operasi di kalangan praktisi dokter hewan jarang bahkan tidak pernah dilakukan. Tujuan penelitian ini adalah mengetahui tingkat efektifitas penggunaan gloves steril selama proses operasi (intraoperasi) dan post operasi ovariohisterektomi dengan melihat total kuantitas bakteri yang didapatkan pada sampel gloves steril. Dua belas sampel dibagi menjadi tiga kelompok perlakuan. Masing-masing kelompok terdiri dari 4 sampel. Kelompok 1 adalah kontrol, swab pada gloves steril dilakukan sebelum operasi dimulai. Kelompok 2 adalah swab pada gloves steril yang dilakukan pada menit ke 30 setelah operasi dimulai. Variabel 3 adalah swab pada gloves steril yang diambil pada menit ke 60 (post operasi). Durasi operasi ovariohisterektomi yang dilakukan berlangsung selama 48 menit. Swab dilakukan dengan menggunakan sterile swabs yang sudah dibasahi menggunakan NaCl steril, kemudian permukaan gloves dengan luas sekitar 5 cm x 5 cm diusab dan sampel direndam dalam konikel berisi NaCl steril. Sampel kemudian dikirim ke Departemen Kesehatan Masyarakat Veteriner FKH UGM untuk pengujian Total Plate Count (TPC). Data yang diperoleh selanjutnya diuji statistik menggunakan one way ANOVA. Hasil pemeriksaan TPC menggunkan analisis statistik one way ANOVA. Hasil penelitian menunjukkan bahwa CFU/ml glove control (4550±5193,9), glove pada menit ke-30 operasi (10075±14747,5) dan glove setelah 60 menit operasi (27000±48764,7). Kesimpulan, tingkat efektifitas glove steril pada menit ke-0, ke-30 dan ke-60 operasi tidak menunjukkan perubahan yang signifikan (P>0.05) terhadap jumlah bakteri. Dengan demikian, tidak adanya perubahan signifikan jumlah koloni bakteri selama 48 menit selama operasi berlangsung dan post operasi (menit ke-60), maka penggunaan glove steril tidak perlu diganti dengan syarat tidak terdapat robekan, perforasi mikros atau tusukan pada glove steril.
Manajemen Pengelolaan Badan Usaha Milik Desa (BUMDes) di Desa Wisata Lumbung Stroberi Kota Batu Anggraeni, Devita; Sekarsari, Retno Wulan; Said, M. Mas`ud
RIGGS: Journal of Artificial Intelligence and Digital Business Vol. 4 No. 3 (2025): Agustus - October
Publisher : Prodi Bisnis Digital Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/riggs.v4i3.2898

Abstract

Penelitian ini memiliki tujuan guna mengetahui bagaimana strategi manajemen dalam pengelolaan Badan Usaha Milik Desa (BUMDes) di Desa Wisata Lumbung Stroberi Kota Batu. Latar belakang penelitian ini dilandasi oleh potensi agrowisata stroberi di Desa Pandanrejo yang dikelola melalui BUMDes. Metode penelitian menggunakan pendekatan  deskriptif kualitatif dengan teknik pengumpulan data melalui wawancara, observasi, dan dokumen-tasi. Adapun analisis data dilakukan menggunakan tiga tingkatan strategi menurut John A. Pearce dan Richard B. Robinson, Jr yakni strategi tingat korporasi, bisnis dan fungsional, selain itu analisi data juga dilakukan dengan pendekatan fungsi-fungsi  manajemen menurut George R. Terry, yaitu perencanaan (planning), pengorganisasian (organizing), pengarahan (actuating), dan pengawasan (controlling). Dari penelitian yang dilakukan, ditemukan bahwa pengelolaan BUMDes masih belum optimal, ditandai dengan belum adanya dokumen rencana strategis, pembagian tugas yang belum merata serta pengawasan yang belum sistematis. Hambatan lainnya meliputi kerja sama informal dengan petani, keterbatasan pasar, dan kurangnya dukungan pihak swasta. Partisipasi pemuda desa cukup baik, namun pemberdayaan petani masih kurang maksimal. Adapun saran yang bisa diberikan dalam penelitian ini yakni penguatan strategi berbasis fungsi manajemen serta kolaborasi multipihak untuk mendorong keberlanjutan usaha desa. 
Community Services at SMP Bina Siswa Kotabaru Sub-district West Bekasi District in 2023 Sasabone, Restichia; Siauta, Jenny Anna; Adinda, Paula Natasa Sindy; Sagala, Kristina; Venancyana, Maria Chandra; Purba, Rohani; Bonita, Bonita; Anggraeni, Devita
International Journal of Community Services Vol. 1 No. 1 (2023): InJCS Vol 1 No 1 (2023)
Publisher : Rajaki of Tulip Medika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61777/injcs.v1i1.5

Abstract

Background: Health problems receive serious attention from various elements ofsociety. One way to solve health problems in the community is to carry out communityservice. Community service is an activity that aims to assist the community in severalactivities to overcome the problems they face by actively participating in the healthdevelopment process and increasing community empowerment without expecting anyform of reward. Objective: Carry out community service activities by carrying out activities rangingfrom collecting secondary data to conducting interventions and evaluating fieldactivities. Method: The practice of community midwifery carried out by Nasional UniversityMidwife Professional Education Students Batch 5 Group 3 with the practice area at theYusma Medika Clinic which was carried out at the Bina Siswa Utama Middle School,Kotabaru Subdistrict, West Bekasi District, Bekasi City, has been carried out in thefollowing stages: Orientation, Taking Secondary Data, Focus Group Discussion (FGD),Preparation of Planning Of Action (POA), Intervention activities in the form ofcounseling about "Ceria Manise" (Preventing Anemia of Adolescents with NutritiousFood and Fe Supplementation) and giving herbal drink "Ceria Flowers" (Dragon Fruitand Honey Prevents Adolescents from Anemia), and ends with Evaluation and Closing. Result: Community service activities in the form of counseling "Ceria Manise"(Prevent Anemia of Adolescents with Nutritious Food and Fe Supplementation) andprovision of the herbal drink "Ceria Flowers" (Dragon Fruit and Honey Prevent Anemiain Adolescents) are expected to allow adolescents to understand more about anemia andcan take proper prevention, one of which is by consuming dragon fruit and honey herbaldrinks. Conclusion: Community service activities in the form of counseling to adolescent girlsabout 'CERIA MANISE' where health information is given on how to prevent anemiawith nutritious food and Fe supplementation
UPAYA PENINGKATAN KEMAMPUAN BERHITUNG MATERI PERKALIAN MENGGUNAKAN PAPAN PERKALIAN SISWA KELAS II Anggraeni, Devita; Rointan Sipangkar; Salsa Sabila Dwi Amorita; Shalfa Annisa Putri Adiwirya; Ryan Dwi Puspita; Sylvia Rabbani
JESA-Jurnal Edukasi Sebelas April Vol 8 No 2 (2024): JESA - Jurnal Edukasi Sebelas April
Publisher : LPPM UNSAP & Fakultas Keguruan dan Ilmu Pendidikan

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Abstract

Penelitian ini dilatarbelakangi oleh ketidakmampuan siswa dalam berhitung pada materi perkalian. Hal ini merupakan permasalahan yang sering dihadapi oleh guru dan siswa di sekolah dasar. Metode penelitian yang digunakan adalah Penelitian Tindakan Kelas (PTK) dari Kemmis&Taggart. Langkah-langkah yang dilakukan pada penelitian ini adalah perencanaan, pelaksanaan tindakan, observasi, dan refleksi. Subjek dalam penelitian ini diambil pada kelas II dengan jumlah 25 siswa. Teknik pengumpulan data dalam penelitian ini adalah wawancara, observasi, tes, dan angket. Hasilnya menunjukkan pada siklus ke-1 84 % dan siklus ke-2 92 %. Hal ini menunjukkan bahwa terdapat peningkatan kemampuan berhitung perkalian di siklus ke-1 dan siklus ke-2 dengan menggunakan media papan perkalian.
THE EFFECTIVENESS OF ETHANOL EXTRACT OF BINAHONG LEAVES ON DIABETIC WOUND HEALING Anggraeni, Devita; Airin, Claude Mona; Raharjo, Slamet
Jurnal Kedokteran Hewan Vol 11, No 4 (2017): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v11i4.6562

Abstract

This research aimed to study the effectiveness of ethanol extract of binahong leaves on blood glucose, insulin, blood chemical profiles (serum glutamic pyruvate transaminase=SGPT, serum glutamic oxaloacetic transaminase=SGOT, ureum, and creatinine), and skin histopathology in diabetic rat. A total of 20 male Wistar rats aged 3 months ( 250 gram) were divided into five groups, with four rats in each group. Group I (non-diabetic control) was injected with 0.1 M sodium citrate buffer, while group II (diabetic control), III, IV, and V were injected with single dose of Streptozotocin (STZ) at dose 40 mg/kg intraperitoneally (IP). One week after the injection, the dorsal skin of the rats were excised. Group I and II were given cream topically and 1% NaCMC orally, group III was given 50% ethanol extract of binahong leaves (EEB) topically and 1% NaCMC orally, group IV was given cream topically and EEB 300 mg/kg orally, and group V was given 50% EEB topically and EEB 300 mg/kg orally. These treatments were continued for 14 days. Blood samples were obtained at the end of study to examine blood glucose, insulin, and blood chemical profiles (SGOT, SGPT, ureum, and creatinine). Examination of skin histopathology and leukocyte count were also done. The result showed that blood glucose, insulin, SGOT, SGPT, and ureum level of diabetic rats given topical or oral EEB did not significantly different from diabetic control group, even though blood glucose, insulin, SGOT, SGPT, and ureum level of diabetic rats given topical and oral EEB were found lower compared to diabetic control group. Administration of EEB 300 mg/kg orally in diabetic rats could lower creatinine level significantly (P0.05). Histopathological examination of dorsal skin of diabetic rats which were given EEB topically showed the decrease of fibroblast proliferation, leukocyte infiltration, and hemorrhage in dermis area. Leukocyte count on skin tissue was significantly lower (P0.05) in diabetic rats given EEB. In conclusion, topical or oral administration of EEB can help healing process in diabetic wound.
THE EFFECTIVENESS OF THE COMBINATIONS OF CALCITRIOL AND ETHYNIL ETHYL ESTRADIOL TO DECREASE OSTEOPOROSIS AND ENDOMETRIAL CANCER RISKS IN OVARIECTOMIZED RATS Hartiningsih, Hartiningsih; Anggraeni, Devita
Jurnal Kedokteran Hewan Vol 11, No 2 (2017): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v11i2.4895

Abstract

The objective of this research was to study the effectiveness of calcitriol and ethynil ethyl estradiol combinations to decrease osteoporosis and endometrial cancer risks in ovariectomized Wistar rats. Twenty five 8-week old female Wistar rats were randomly divided into five groups (normal controlled rats/NK, ovariectomized rats/OVK, ovariectomized rats + calcitriol supplementation/OVD, ovariectomized rats + ethynil ethyl estradiol supplementation/OVE, and ovariectomized rats + calcitriol + ethynil ethyl estradiol supplementation/OVDE). At the end of the study, all rats were weighed and euthanized with 10% ketamine and 2% xylazine. Uterus and left femur were taken and fixed in 10% formaldehyde solution for histopathological examination using hematoxylin and eosin stain. Uterus was weighed before the fixation. The results showed that the percentage of uterus weight in OVK was significantly decreased compared to NK. Meanwhile, the percentage of uterus weight in OVDE was significantly increased compared to OVK. Histopathological features of the uterus in OVK were atrophy, reduction of myometrial and endometrial layers thickness, and formation of cuboidal epithelium in the endometrial lumen. However, the thickness of myometrial and endometrial layers in OVDE were increased, and its endometrial lumen was lined with metaplastic and hyperplastic squamous cell. Histopathological features of distal femur epiphysis in OVK ras showed fewer trabecular spiculums and more adipocyte in the bone marrow compared to NK. However, OVDE had more trabecular bone spiculum and less adipocyte in the bone marrow compared to OVK. In conclusion, the combination of calcitriol and ethynil ethyl estradiol supplementation could reduce osteoporosis, but increased the endometrial cancer risk in ovariectomized Wistar rats.
EFEKTIVITAS DIET TERI TAWAR DAN SUPLEMENTASI KALSITRIOL UNTUK MENCEGAH OSTEOPOROSIS PADA TIKUS OVARIEKTOMI The Effectiveness of Fresh Anchovies Diet and Calcitriol Supplementation to Prevent Osteoporosis in Ovariectomized Rats (The Effectiveness of Fresh Anchovies Diet and Calcitriol Supplementation to Prevent Osteoporosis in Ovariectomized Rats) H, Hartiningsih; Anggraeni, Devita; S, Sudarminto
Jurnal Kedokteran Hewan Vol 10, No 1 (2016): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v10i1.3362

Abstract

This study was conducted to assess the effectiveness of a diet contained fresh anchovies and calcitriol supplementation for 6 weeks to prevent osteoporosis in ovariectomized rats. Fifteen Wistar rats aged 8 weeks were divided randomly into 3 groups (normal/K, ovariectomized/Ov, and ovariectomized + calcitriol/OVD), 5 mice each. Group K and Ov rats were fed with fresh anchovies, while the OVD group was fed with fresh anchovies + calcitriol. At the age of 15 weeks, all mice were done for euthanasia, then left femur was collected for immunohistochemistry examination of tartrate resistant acid phosphatase5b (TRAP5b). The detection of (TRAP5b) was conducted using a monoclonal ant ibody anti TRAP5b, and detected using a streptavidin-biotin. The results showed that the metaphysis part of distal femur bone of mice group K, Ov, and OVD were positive TRAP5b stained with brown color on trabecular bone in bone marrow cavity and trabecular spiculum surface, but rats in group K and Ov had extensive bone marrow cavity and normal trabecular spiculum, whereas OVD group showed bone marrow cavity dilation, accumulation of adipocytes in the bone marrow cavity, and shorter the spiculum of trabeculae. It can be concluded that fresh anchovies diet and calcitriol supplementation for 6 weeks are not effective in preventing osteoporosis in ovariectomized rats.Key words: calcitriol, femur, ovariohisterectomy
KESEMBUHAN LUKA SETELAH PEMBERIAN TOPIKAL ZINK PADA TIKUS DENGAN PAKAN LEMAK TINGGI Anggraeni, Devita; Adji, Dhirgo; Murwanti, Retno
Jurnal Kedokteran Hewan Vol 9, No 2 (2015): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v9i2.2809

Abstract

Penelitian ini bertujuan mengetahui peran zink pada kesembuhan luka dalam kondisi berat badan berlebih. Dalam penelitian digunakan 20 ekor tikus Sprague Dawley jantan berumur tiga bulan (150-200 g). Tikus dibagi secara acak menjadi empat kelompok (A, B, C, dan D), masing-masing kelompok terdiri atas lima ekor. Kelompok A dan B diberi pakan normal, sedangkan kelompok C dan D diberi pakan lemak tinggi. Setelah dua bulan perlakuan pakan, seluruh tikus dioperasi untuk membuat luka irisan pada kulit, kemudian luka ditutup dengan jahitan. Luka jahitan pada kelompok A dan C diberi aplikasi topikal unguenta vaseline album (tanpa zink), sedangkan luka jahitan pada kelompok B dan D diberi aplikasi topikal unguenta zink 10% dengan bahan dasar vaselin album. Lima hari setelah operasi, seluruh tikus diambil darahnya untuk dianalisis terhadap jumlah leukosit total kemudian diikuti pengambilan jaringan kulit untuk pemeriksaan histopatologis dan penghitungan jumlah leukosit di jaringan. Hasil penelitian menunjukkan adanya interaksi yang signifikan antara pakan dan aplikasi topikal terhadap jumlah leukosittotal dalam darah (P0,05). Jumlah leukosit di jaringan mengalami penurunan setelah aplikasi topikal zink, meskipun hasilnya tidak signifikan (P0,05). Analisis histopatologis menunjukkan epidermis sudah tertutup pada seluruh tikus perlakuan, namun demikian sebagian tikus masih menunjukkan dermis yang terbuka, yaitu kelompok A sebanyak 60%, kelompok B sebanyak 60%, kelompok C sebanyak 60%, dan kelompok D sebanyak 40%. Dapat disimpulkan bahwa proses kesembuhan luka setelah pemberian topikal zink pada tikus yang diberi pakan lemak tinggi menunjukkan hasil yang baik, yaitu ditandai dengan penutupan lapisan epidermis dan dermis, serta menurunnya jumlah leukosit di jaringan.
Co-Authors Adinda, Paula Natasa Sindy Agus Purnomo Bonita, Bonita Claude Mona Airin Dhirgo Adji Hartiningsih h Hartiningsih Hartiningsih Imron, M.A. Prastiwi, Artina Purba, Rohani Rabbani, Sylvia Ramadhani, Mungky Ema Retno Murwanti Retno Wulan Sekarsari Rointan Sipangkar Ryan Dwi Puspita Sagala, Kristina Said, M. Mas`ud Salsa Sabila Dwi Amorita Sasabone, Restichia Shalfa Annisa Putri Adiwirya Siauta, Jenny Anna Slamet Raharjo Sudarminto S, Sudarminto Venancyana, Maria Chandra Wisnu Nurcahyo