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All Journal Jurnal Kesehatan Indonesia Muhammadiyah Journal of Nutrition and Food Science (MJNF) Muhammadiyah Journal of Geriatric Muhammadiyah Medical Journal Jurnal Pengabdian Masyarakat Medika
Tubarad, Gladys Dwiani Tinovella
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Correlation between Interleukin-6 with D-dimer and C-reactive protein Levels in Patients with Confirmed COVID-19 Severe Criteria Gemintang, Ghea Setia; Wiratmoko, Raden Mirsyam Ratri; Tubarad, Gladys Dwiani Tinovella
Muhammadiyah Medical Journal Vol 5, No 2 (2024): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.5.2.69-75

Abstract

Background: In Coronavirus Disease 2019 (COVID-19) severe criteria, cytokine storm conditions are often found, and there will be an increase in Interleukin-6 as a cytokine and CRP as an acute phase protein induced by IL-6. In COVID-19 patients with severe criteria, coagulation disorders can also be found, characterized by an increase in the D-dimer value. Purpose: To determine the correlation between IL-6, D-dimer, and CRP levels in patients with confirmed COVID-19 severe criteria at Bunda Margonda General Hospital in 2021. Methods: This research was an analytical observation study with a cross-sectional approach, using secondary data from medical records of patients with confirmed COVID-19 severe criteria at Bunda Margonda General Hospital in 2021. Results: The number of patients with confirmed COVID-19 severe criteria was primarily male (59%), aged 46-55 years (33%), with degree of severity with severe criteria in 100 patients, increased IL-6 (91%), increased D-dimer levels (90%), increased CRP levels (95%). There was a correlation between increased IL-6 with D-dimer levels (p-value 0,005) and a correlation between increased IL-6 with CRP levels (p-value of 0,000). A simultaneous and significant relationship was found between IL-6, D-dimer, and CRP levels in severe COVID-19 criteria. COVID-19 patients with severe criteria were more commonly found in males in the 46-55-year age group with increased IL-6, D-dimer, and CRP values. Conclusion: There was a correlation between increased IL-6 and D-dimer and CRP levels in COVID-19 patients with severe criteria at Bunda Margonda General Hospital in 2021.
Descriptive Study: Attitude and Behaviour Regarding Oral Corticosteroid Use in Bebita Clinic Cicurug, Sukabumi in 2019 Nabila, Audia Nizhma; Tubarad, Gladys Dwiani Tinovella; Azzahra, Vanianissa
Muhammadiyah Medical Journal Vol 3, No 1 (2022): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.3.1.10-18

Abstract

Background: Corticosteroids are derivatives of steroid hormones that have the effect of inhibiting the inflammatory response. Glucocorticoid is the type of corticosteroid that is easy to obtain and has a high anti-inflammatory effect. Therefore, glucocorticoids are often used in various therapies. However, the use of this drug should be monitored since its side effects can be harmful to the health as paralytic effects or even lethal effects. Purposes: This study aims to determine the behavior of using oral corticosteroids in patients at the Bebita Cicurug Clinic, Sukabumi. Methods: This is a descriptive quantitative research study. Data collection was done from September to December 2019. The respondents of this study were 96 subjects of Bebita Cicurug Clinic with a history of oral glucocorticoid usage. The data was taken using a questionnaire and medical records. Result: The most widely used glucocorticoid type is Methylprednisolone 4 mg and dexamethasone 0,5 mg. Overall, 89.6% of respondents used corticosteroids for a week or less. A total of 21.9% had tried to get corticosteroids without a prescription (self-medication), and all of them didn't get restricted on purchasing corticosteroids. Conclusion: In general, patients in this study had good behavior in using corticosteroids (using steroids according to a doctor's prescription), but 21.9% had tried to get corticosteroids without a prescription, and all of them didn't get restricted on purchasing corticosteroids. Doctors and health workers must clearly explain prescribed drugs' benefits and side effects, especially in patients with chronic diseases. Then ensure that the patient has understood the benefits and side effects of the medications used.
Hubungan Indeks Massa Tubuh dengan Kadar Gula Darah Puasa pada Mahasiswa Program Studi Kedokteran Universitas Muhammadiyah Jakarta Wahyuni, Tri; Nauli, Anggi; Tubarad, Gladys Dwiani Tinovella; Hastuti, Murni Sri; Utami, Meita Dwi; Sari, Tirta Prawita
Muhammadiyah Journal of Nutrition and Food Science (MJNF) Vol 2, No 2 (2021): Muhammadiyah Journal of Nutrition and Food Science (MJNF)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mjnf.2.2.88-94

Abstract

Latar belakang: Obesitas adalah akumulasi lemak berlebihan yang tidak normal yang dapat merusak kesehatan, hal ini dapat diukur dengan index massa tubuh dengan membagi berat badan (kg) dan tinggi badan (m2) untuk melihat seseorang berat badan lebih atau kurang. Masalah obesitas dimulai pada tahun 1975 hingga tahun 2016 ini, diperkirakan 1,9 miliar orang dewasa dari penduduk seluruh dunia usia +18 tahun mengalami kelebihan berat badan. Di Indonesia masalah obesitas masih tinggi salah satunya DKI Jakarta (30%). Obesitas dapat menyebabkan berbagai penyakit. Hal ini dapat terjadi karena lemak yang berlebih dalam tubuh dapat dimetabolisme menjadi gula dalam darah sehingga menyebabkan peningkatan gula darah, jika hal ini dibiarkan akan terjadi hiperglikemia. Keadaan hiperglikemia ini bisa menyebabkan penyakit diabetes melitus. Tujuan: untuk mengetahui hubungan indeks massa tubuh dengan kadar gula darah puasa pada mahasiswa Program Studi Kedokteran UMJ tahun 2018. Metode: Penelitian ini deskriptif analitik dengan pendekatan cross sectional. Pengambilan data sampel dengan teknik total sampling seluruh mahasiswa Program Studi Kedokteran UMJ 2018 di kampus A Cirendeu berjumlah 109 orang. Analisis uji statistik dengan uji korelasi Rank Spearman (CI = 95% dan α = 5%). Hasil: Hasil uji Rank Spearman menunjukkan bahwa tidak terdapat hubungan yang signifikan antara kadar Indeks Massa Tubuh dengan Kadar Gula Darah Puasa dengan nilai p-value adalah 0,07 dan nilai korelasi adalah 0,22.  Ada kemungkinan jika variabel kadar IMT tinggi maka kadar Gula Darah Puasa juga bisa tinggi. Simpulan: Tidak terdapat hubungan signifikan antara Indeks Massa Tubuh dengan Kadar Gula Darah Puasa pada Mahasiswa Program Studi Kedokteran UMJ 2018.
Profil Komponen Sindroma Metabolik pada Pasien Diabetes Mellitus (DM) Usia Lanjut di Rumah Sakit Islam Jakarta Cempaka Putih Wahyuni, Tri; Hastuti, Murni Sri; Chahyani, Wiwit Ida; Shabrina, Fida' Alia; Tubarad, Gladys Dwiani Tinovella
Muhammadiyah Journal of Geriatric Vol 4, No 1 (2023): Muhammadiyah Journal of Geriatric
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mujg.4.1.23-34

Abstract

Latar Belakang: Prevalensi diabetes mellitus (DM) global pada tahun 2021 diperkirakan lebih dari setengah miliar orang hidup dengan diabetes di seluruh dunia. Prevalensi diabetes tertinggi pada usia 75-79 tahun. Mortalitas DM berhubungan dengan komplikasi yang terjadi. Komplikasi DM terjadi karena kadar glukosa yang tidak terkontrol dengan baik sehingga menimbulkan komplikasi makro dan mikrovaskuler. Tujuan: Mengetahui kadar trigliserida, kolesterol total, LDL, HDL, asam urat dan gula darah sewaktu pada pasien geriatri dengan DM. Metode: Penelitian ini menggunakan metode deskriptif. Subjek yang diikutsertakan dalam penelitian ini merupakan kelompok usia 45-90 tahun dan dilakukan pemeriksaan trigliserida, kolesterol total, LDL, HDL, asam urat dan gula darah sewaktu. Hasil: Dari 30 subjek penelitian yang diperiksa, ditemukan dominan dengan jenis kelamin perempuan sebanyak 60%. Usia subjek penelitian, dominan pada kategori lansia akhir (56-64 tahun) sebanyak 46.7%. Kadar gula darah sewaktu sebagian besar pada kategori normal sebanyak 60%. Kadar trigliserida dominan pada kategori tinggi (≥150 mg/dl) sebanyak 70%. Kadar kolesterol total paling banyak ditemukan pada kategori yang diinginkan (200 mg/dL) sebesar 66.7%. Kadar LDL dominan pada kategori optimal (100 mg/dL) sebanyak 46.7%. Kadar HDL sebagian besar pada kategori rendah (40 mg/dL) sebanyak 50%. Asam urat sebagian besar pada kadar tinggi sebanyak 63.3%. Simpulan: Peningkatan kadar gula darah sewaktu, kadar trigliserida, kolesterol total, LDL, asam urat dan penurunan kadar HDL subjek penelitian ditemukan sebagian besar pada usia lansia akhir.
SKRINING FUNGSI KOGNITIF DAN KADAR ASAM URAT PADA PESERTA PROLANIS KLINIK DOKTER KELUARGA Purwoko, Mitayani; Heriyanto, Mochammad Junaidy; Sulistiyani, Sulistiyani; Sriningsih, Solikah; Putra, Chendra Perdana; Gani, Rima January Putri Ridwan; Prakoso, Denny Anggoro; Novitasari, Erlina Krisdianita; Tubarad, Gladys Dwiani Tinovella; Sukarno, Rizky Triutami; Rudiyanto, Waluyo; Pandhita, Gea; Aziza, Nurita; Tursinawati, Yanuarita; Airlangga, Muhammad Perdana; Setiawan, Meddy; Romi, M. Mansyur
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 2, September 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i2.12547

Abstract

ABSTRAK Fungsi kognitif dan kadar asam urat darah lansia tidak termasuk dalam pemeriksaan wajib dalam program Prolanis. Fungsi kognitif perlu dinilai untuk memastikan bahwa peserta Prolanis tidak mengalami kemunduran fungsi kognitif. Tujuan kegiatan ini adalah untuk melakukan skrining tingkat fungsi kognitif dan kadar asam urat darah peserta Prolanis di Klinik Dokter Keluarga Fakultas Kedokteran Universitas Muhammadiyah Palembang. Kegiatan dilaksanakan dalam satu hari selama 2 jam 30 menit. Pemeriksaan fungsi kognitif dilakukan menggunakan kuesioner Mini Mental State Examination (MMSE) berbahasa Indonesia. Pemeriksaan kadar asam urat darah dilakukan menggunakan darah dari ujung jari dengan alat pemeriksa asam urat dan strip khusus. Hasil skrining menunjukkan bahwa 80,4% peserta Prolanis memiliki fungsi kognitif yang normal dan 66,7% memiliki kadar asam urat darah yang normal.   ABSTRACT Cognitive function and blood uric acid levels in the elderly are not included in the mandatory screening in the Prolanis program. Cognitive function needs to be assessed to ensure that Prolanis participants do not experience cognitive decline. The purpose of this activity was to screen the cognitive function and blood uric acid levels of Prolanis participants at the Family Physician Clinic, Faculty of Medicine, Muhammadiyah University of Palembang. The activity was carried out in one day for 2 hours and 30 minutes. Cognitive function testing was conducted using the Indonesian language Mini Mental State Examination (MMSE) questionnaire. Blood uric acid testing was performed using fingertip blood with a uric acid tester and special strips. The screening results showed that 80.4% of Prolanis participants had normal cognitive function and 66.7% had normal blood uric acid levels.
Tingkat Pemahaman Mahasiswa Preklinik dan Klinik Fakultas Kedokteran dan Kesehatan Universitas Muhammadiyah Jakarta terhadap Kaidah Dasar Bioetika dan Perilaku Penilaian Moral Muchlis, Ahmad; Syafruddin, Amir; Tubarad, Gladys Dwiani Tinovella; Sabrina, Annaya Noor
Jurnal Kesehatan Indonesia Vol 14 No 2 (2024): Maret 2024
Publisher : HB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33657/jurkessia.v14i2.910

Abstract

Essentially, a doctor is evaluated not only by his capability to treat disease, but also by his ability to make choices in order to keep both the patient and the doctor in question while adhering to the applicable norms and regulations. As a result, medical students must understand the fundamental principles of bioethics and make proper ethical judgements. The objective of this research is to evaluate preclinical and clinical students' awareness of basic bioethics concepts at Muhammadiyah University Jakarta's Faculty of Medicine and Health. The Simple Cross-sectional approach was used on 83 students, 43 preclinical and 40 clinical, by using study instruments Basic Bioethical Rules Test (KDB) and Moral Research Test (UPM). The study's end goal is to uncover preclinical and clinical students' thoughts on how KDB and UPM might be implemented, not just as information that can be formed as output in the form of writing and scientific infographic posters.
Co-Authors Ahmad Muchlis Aziza, Nurita Azzahra, Vanianissa Chahyani, Wiwit Ida Gani, Rima January Putri Ridwan Gemintang, Ghea Setia Hastuti, Murni Sri Heriyanto, Mochammad Junaidy M. Mansyur Romi Meddy Setiawan Mitayani Purwoko, Mitayani Muhammad Perdana Airlangga, Muhammad Perdana Nabila, Audia Nizhma Nauli, Anggi Novitasari, Erlina Krisdianita Pandhita, Gea Prakoso, Denny Anggoro Putra, Chendra Perdana Rudiyanto, Waluyo Sabrina, Annaya Noor Sari, Tirta Prawita Shabrina, Fida' Alia Sriningsih, Solikah Sukarno, Rizky Triutami SULISTIYANI SULISTIYANI Syafruddin, Amir tri wahyuni Utami, Meita Dwi Wiratmoko, Raden Mirsyam Ratri Yanuarita Tursinawati, Yanuarita