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All Journal Journal of Biomedicine and Translational Research Jurnal Respirologi Indonesia Jurnal Kedokteran Universitas Palangka Raya Respiratory Science Narra J Kieraha Medical Journal Cermin Dunia Kedokteran
Jatu Aphridasari
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Comparison of NEWS, SIRS, and qSOFA Score as Predictors of Mortality and Length of Stay in Patients Pneumonia with Sepsis Harsini, Harsini; Alfarizi, Aditya; Aphridasari, Jatu; Raharjo, A Farih; Reviono, Reviono
Jurnal Respirologi Indonesia Vol 44 No 1 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i1.505

Abstract

Background: Pneumonia is a major health problem in all age groups and often related with sepsis. In 2021, Surviving Sepsis Campaign Guidelines mentioned several clinical scoring systems to identify patients with potentials of developing sepsis, such as systemic inflammatory response syndrome (SIRS), national early warning score (NEWS), quick sequential organ failure assessment (qSOFA) and sequential organ failure assessment (SOFA). The guideline stated that there is no gold standard for diagnosing sepsis, contradicting The Sepsis-3 Guideline in 2016 that mentioned SOFA score as a gold standard for diagnosing sepsis.Methods: Subjects were all patients with pneumonia and sepsis who were treated in Dr.Moewardi Hospital within 1 January to 31 December 2022. Data from subjects’ medical records were collected to assess their NEWS, SIRS, qSOFA, and SOFA score on the day of admission. Since evaluation of SOFA score needs a number of components requiring laboratory results and takes longer time so they made a simpler tool called qSOFA to avoid delayed treatment of the patients.Results: NEWS is more consistent with SOFA compared to SIRS and qSOFA (Kappa value = 0.726 vs 0.320 vs 0.22; respectively). NEWS, SIRS, and qSOFA were all significantly correlated with mortality (P<0.001) with NEWS having the strongest correlation (r=0.482 vs 0.216 vs 0.175; respectively). Only NEWS showed significant correlation with the length of stay (r=0.129; P<0.001).Conclusion: NEWS was the most consistent score to SOFA compared to SIRS and qSOFA. NEWS was also the best predictor for mortality and was the only score correlated with length of hospital stay.
Co-Authors . Widardo AA Sudharmawan, AA Adhiputri, Artrien Alfarizi, Aditya Ana Rima Setijadi Apriningsih, Hendrastutik Astari Rindu Astuti Astarini, Dewi Bahari, Muh Arif Wira Fachry Abda El Rahman Fahlevie, Fahlevie Harnanda, Dicki Harsini Harsini Helmi Fakhruddin Heni Hastuti Nadiya Aliyah Roselyn Novita Silvana Thomas, Novita Silvana Oktavera Tri Kurniasih Raharjo, A Farih Reviono Reviono Rudiannor, Muhammad Septiawan, Debree Siti Munawaroh Sumardiyono . Sutanto, Yusup S. widardo, Widardo Widyasanti, Diana Windu Prasetyo, Windu Yusup Subagio Sutanto