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All Journal Jurnal Pengabdian UntukMu NegeRI Indonesian Journal of Health Sciences Research and Development (IJHSRD) MOSIRAHA : Jurnal Pengabdian Farmasi Lansau: Jurnal Ilmu Kefarmasian
Nur Illiyyin Akib
Universitas Halu Oleo
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Journal : Lansau: Jurnal Ilmu Kefarmasian

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Formulasi dan Karakterisasi Sediaan Spray gel Ekstrak Etanol Buah Pare (Momordica charantia L): Formulation dan Characterization of Ethanol Extracts Spray gel of Bitter Melon (Momordica charantia L.) Fruit Nur Illiyyin Akib; Sabarudin; Sitti Raodah Nurul Jannah; Desi Nur Sholiha
Lansau: Jurnal Ilmu Kefarmasian Vol. 1 No. 1 (2023): Lansau: Edisi April 2023
Publisher : Fakultas Farmasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33772/lansau.v1i1.6

Abstract

Bitter melon (Momordica charantia L.) fruit has been empirically used as an antibacterial and reported to have activity against acne-causing bacteria. This study aimed to formulate bitter melon ethanol extract in a spray gel preparation and test its activity against Staphylococcus epidermidis as one of the acne-causing bacteria. Pare fruit extract concentrations of 0.5%, 1%, and 2.5% are formulated into spray gel preparations with additional ingredients, Carbopol 940 0.1%, triethanolamine 0.5%, propylene glycol 15%, DMDM Hydantoin 0.6% and aquadest. The characterization of the physical properties of the spray gel preparation included organoleptic, homogeneity, pH, viscosity, and dry time test. The results showed that the spray gel preparation of ethanol extract of Pare fruit had a liquid texture, brownish-yellow colour, and distinctive odour and was homogeneous. The spray gel preparation also meets pH, viscosity and dry time requirements. The antibacterial activity of spray gel preparations resulted in a diameter response of potent and robust inhibition.
Co-Authors Asriullah Jabbar Desi Nur Sholiha Elvantri Yani Fadilah Fadilah Fery Indradewi Halik Halik Halik Hasnawati Hasnawati Imran Imran Irmawati Irmawati Irvan Anwar Kasmawati, Henny Muamal Gadapi Mubarak Mubarak Nur Rayani Nurramadhani A. Sida Parawansah Parawansah Ritha Hastria Ruslin Ruslin SABARUDIN Sitti Raodah Nurul Jannah Sugireng Sugireng Tasnim Tasnim Vica Aspadiah Wa Ode Yentri Putia Ningtiyas Darmin