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All Journal TELKOMNIKA (Telecommunication Computing Electronics and Control) Indonesian Journal of Electrical Engineering and Informatics (IJEEI) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Indonesia Journal of Physical Medicine and Rehabilitation Indonesia Journal Physical Medicine and Rehabilitation Cermin Dunia Kedokteran Jurnal Ilmu Medis Indonesia Jurnal Widya Medika Cermin Dunia Kedokteran
Pawana, I Putu Alit
Department Of Physical Medicine And Rehabilitation, Faculty Of Medicine, Universitas Airlangga, Dr. Soetomo Academic General Hospital, Surabaya, East Java, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Physics Public Health

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Journal : Indonesia Journal Physical Medicine and Rehabilitation

 1 
Comparison of Neutrophyl Lymphocyte Ratio and Nerve Conduction Study Between Male Type 2 Diabetes Mellitus With or Without Peripheral Neuropathy Complication Martha Kurnia Kusumawardani; Surdiana; I Putu Alit Pawana; Sony Wibisono
Indonesian Journal of Physical Medicine & Rehabilitation Vol 11 No 01 (2022): Indonesian Journal Of Physical Medicine and Rehabilitation
Publisher : Indonesian Journal of Physical Medicine & Rehabilitation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36803/ijpmr.v11i01.326

Abstract

ABSTRACT Background: Diabetic Peripheral Neuropathy (DPN) is one of the type 2 Diabetes Melitus (T2DM) complication, which may lead to diabetic foot ulcer and lower extremity amputation. Inflammation plays a role in the pathogenesis of this type 2 DM complication. Recent studies showed neutrophyl-lymphocyte ratio (NLR) is a potential inflammation marker. Early screening for neuropathy is an important part of the medical rehabilitation management of this condition. Material and methods: This study uses data analysis independent sample T-2 test with a significant (p<0.05). This study is a analytic observation cross-sectional study with type 2 diabetic male subjects, screened with Michigan Neuropathy Screening Instrument then divided into 2 groups, with DPN group (11 subjects) and without DPN group (7 subjects). This was followed with complete blood count laboratory testing (neutrophyl and lymphocyte level) and NCS to measure distal latency, amplitudo, and NCV of the tibial, peroneal, and suralnerve on both lower extremities. Result: There were 18 subjects in this study. Independent T-2 test showed that there was no significant difference in neutrophils (p=0.679), lymphocytes (p=0.127), and NLR (p=0.190) in the DM group without or with neuropathy. NCS showed that there were significant differences on the amplitude of the three nerves peroneal (p=0.003), tibial (p=0.017), sural (p=0.033), also in NCV of peroneal (p=0.001) and tibial (p=0.008). There were no significant differences found on the three distal latency of peroneal (p=0.074), tibial (p=0.151), sural(p=0.294), and NCV of sural (p=0.262). Conclusions: This study shows that there is no significant difference in NLR on both groups. There were significant differences in the amplitude of the three peroneal, tibial, and sural nerves and the conduction velocity of the peroneal and tibial nerves. However, there was no significant difference in the distal latency of the threeperoneal, tibial, sural, and the NCV of the sural nerves.Keywords: diabetes melitus, diabetic peripheral neuropathy, nerve conduction studies, neutrophyl-lymphocyte ratio, rehabilitation management.
Administration of Oral Curcumin to Resistance Exercise after Immobilization Does Not Affect Skeletal Muscle Fiber Diameter in Rattus Norvegicus I Putu Alit Pawana; Martha Kurnia Kusumawardani; Lydia Arfianti
Indonesian Journal of Physical Medicine & Rehabilitation Vol 11 No 01 (2022): Indonesian Journal Of Physical Medicine and Rehabilitation
Publisher : Indonesian Journal of Physical Medicine & Rehabilitation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36803/ijpmr.v11i01.328

Abstract

ABSTRACTIntroduction: The aim of this study was to explore the effect of adding oral curcumin to resistance exerciseafter immobilization on the diameter of skeletal muscle fiber in Rattus Norvegicus.Methods: This was a post-test only study design on animal model. Subjects of the study were male Rattusnorvegicus strain Wistar, age 10-12 weeks old, weigh between 150-300 g, were immobilized at soleusmuscle for 2 weeks, then randomly allocated to 3 groups: (i) control group, (ii) resistance exercise, (iii)oral curcumin + resistance exercise. After 4 weeks of intervention, the diameter of the muscle fibers wasmeasured.Result: The results of this study showed a significant difference on the diameter of skeletal muscle fiberbetween control group and resistance exercise, as well as control group and resistance exercise + oralcurcumin (p<0.05). There was no significant difference between resistance exercise only and resistanceexercise + oral curcumin (p>0.05).Conclusion: Administration of oral curcumin to resistance exercise after immobilization does not affectskeletal muscle fiber diameter in Rattus Norvegicus.Keywords : curcumin, good health and well-being, immobilization, resist ance exercise, skeletal muscle.
Co-Authors -, Andriati Adrian Utomo Agus Budi Wirawan, I Ketut Gede Andriati Andriati Ayu Susanti, Ayu Bambang Guruh Irianto Damayanti Tinduh Devi Ariani Sudibyo Florentina Sustini Gadiza Raiznintha Permatasari Gusti Agung Ayu Ira Kencana Dewi Hermina Novida, Hermina I Dewa Gede Hari Wisana I Ketut Gede Agus Budi Wirawan I Lukitra Wardhani Imam Subadi Indrato, Tri Bowo Inez Anabela Suprijadi Suprijadi Luthfiyah, Sari Lydia Arfianti Maria, Patricia Martha Kurnia Kusumawardani Masduchi, Reni Hendrarati Meisy Andriana, Meisy Nurul Bashirah Aminy Patricia Maria Putra, Bayu Aji Mayogya Rahmawati, Triana Soenarnatalina Melaniani Sony Wibisono Sri Mardjiati Mei Wulan Subagyo Subagyo Surdiana Torib Hamzah Tri Nurhayati, Yeni Tri Rahayu Septyaningrum Triwiyanto Triwiyanto Wardana, Farid Aditya Wardhani, Indrayuni Lukitra Wardhani, Rr. Indrayuni Lukitra Yuli Indah Kurnia Yusuf Roni