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All Journal International Journal of Public Health Science (IJPHS) Proceedings of KNASTIK Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Science and Technology Indonesia Communications in Science and Technology Jurnal Kebidanan JFL : Jurnal Farmasi Lampung KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Indonesia Berdaya Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Sehat Indonesia (JUSINDO) Jurnal Sains dan Kesehatan
Arif Budi Setianto
Universitas Ahmad Dahlan
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Formulasi dan Optimasi Variasi Basis Carbopol dan Emulgator Terhadap Karakteristik Sediaan Emulgel Husain, Dewi Putri; Kintoko; Setianto, Arif Budi
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/.v7i2.360

Abstract

Emulgel memiliki beberapa kelebihan seperti waktu kontak yang lebih lama, kosistensi yang baik, dapat melembabkan, transparan, mudah penyebaranya, mudah penyerapanya, mudah dihilangkan, dapat bercampur dengan eksipien lain dan larut dalam air. Pembuatan emulgel memerlukan emulgator agar dapat menyatukan dua fase yang berbeda, sediaan dengan emulgator campuran seringkali lebih efektif daripada emulgator tunggal. Penelitian ini bertujuan mengetahui proporsi optimum dari campuran carbopol 940 dan perbandingan konsentrasi tween80 banding span60 sehingga dapat menghasilkan sediaan yang stabil secara fisikokimia. Metode dilakukan dengan memformulasikan sediaan emulgel terlebih dahulu dan diuji fisikokimia meliputi stabilitas, viskositas, daya sebar, daya lekat, nilai pH dan homogenitas. Hasil pengujian didapatkan nilai stabilitas yang baik pada F2 nilai pH sebesar 5.1, viskositas 13.1972 Pa.s, daya sebar 6.05 cm, dan daya lekat 8.80 detik. Analisis data menggunakan One-Way ANOVA dan Kruskal Wallis Test (p<0,05). Berdasarkan nilai rata-rata uji fisikokimia dari setiap pengujian F1, F2, F3, dan F4, dapat disimpulkan bahwa formula optimal yang didapatkan yaitu F2. Hal ini dikarenakan hanya F2 yang memenuhi setiap standar fisikokimia yang telah ditetapkan.
The Description of Knowledge and Attitude of Coffee Lovers on Diabetes Melitus At Coffee Shops In Palaran District: The Description of Knowledge and Attitude of Coffee Lovers on Diabetes Melitus At Coffee Shops In Palaran District Ma'ruf, Muhammad; Setianto, Arif Budi; Lasanudin, Rindi Ibrahim; Yuliani, Sapto
KESMAS UWIGAMA: Jurnal Kesehatan Masyarakat Vol 9 No 2 (2023): December
Publisher : Universitas Widya Gama Mahakam Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/kujkm.v9i2.2224

Abstract

Background: Diabetes mellitus is a disease that is often called "the silent killer." This disorder occurs in the metabolism of carbohydrates and fats that are relatively deficient in insulin in the body. Previous research said that coffee could be used as a therapy for diabetes mellitus. The background for writing this article is the high prevalence of knowledge and attitude of coffee lovers and scientific evidence of coffee content as a decrease in blood glucose levels. Objectives: This study aims to describe the knowledge and attitude of coffee lovers toward diabetes mellitus in coffee shops in Palaran District. Research Metodes: This research method uses quantitative and descriptive. Data were obtained by distributing questionnaires to research subjects, namely coffee lovers who were in coffee shops in the Palaran District, Samarinda City, totaling 46 respondents. Results: The results showed that there were 26 coffee lovers (56.5%) who had good knowledge of diabetes mellitus and 20 people (43.5%) who had a good understanding of diabetes mellitus. Meanwhile, in the attitude of coffee lovers, there were 35 people (76.1%) who had good attitude towards diabetes mellitus and 11 people (23.9%) who had a reasonably good attitude towards diabetes mellitus. Conclusion: It can be concluded that the coffee lovers in the Palaran District coffee shop, on average, have good knowledge and attitude towards diabetes mellitus.
Aktivitas Antibakteri Nanoemulsi Kombinasi Minyak Sereh (Cymbopogon citratus (DC.) Stapf) dan Minyak Kemangi (Ocimum basilicum L.) terhadap Staphylococcus aureus: Antibacterial Activity of Nanoemulsion of Lemongrass Oil (Cymbopogon citratus (DC.) Stapf) and Basil Oil (Ocimum basilicum L.) Combination against Staphylococcus aureus Hasan, Nuradnin; Mulyaningsih, Sri; Setianto, Arif Budi
Jurnal Sains dan Kesehatan Vol. 6 No. 1 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i1.2082

Abstract

Lemongrass oil (Cymbopogon citratus (DC.) Stapf) and basil oil (Ocimum basilicum L.) are secondary metabolites that can be utilized as antibacterials. This study aims to determine the antibacterial activity of nanoemulsion preparation formulations of a combination of lemongrass oil and basil oil against S. aureus bacteria and determine the effective concentration of the mixture of the two. Both oils used were verified including GC-MS analysis, specific gravity, refractive index, solubility in alcohol and acid number. The nanoemulsion preparation formulation contained 4% (v/v) combination of lemongrass oil and basil oil, each fraction consisting of F1 (1:3), F2 (2:2) and F3 (3:1). The resulting preparation was tested for physical properties including organoleptic, homogeneity, viscosity, particle size, pH, irritation test, hedonic test and antibacterial activity test using the pitting diffusion method. The results of GC-MS analysis, lemongrass oil has the main compound components, namely E-citral (38.49%) and Z-citral (25.26%) while basil oil has the main compounds, namely Methyl chavicol (58.14%) and linalool (31.72%). Evaluation of the physical properties of lemongrass oil and basil oil roll-on deodorant preparations met the parameters in accordance with the standard. From the results of the antibacterial activity test for S. aureus, F1 had an inhibition zone of 11.44 ± 2.51 mm, F2 18.89 ± 1.05 mm both included in the strong category and F3 23.78 ± 1.72 mm included in the very strong category. The positive control had a zone of inhibition of 10.56 ± 0.53 mm and the negative control had a zone of inhibition of 0 mm. In conclusion, F3 formulation of roll on deodorant preparation with a combination of lemongrass oil and basil oil (3:1) at 4% has effective antibacterial activity against S. aureus bacteria. Keywords:          Lemongrass oil and basil oil, nanoemulsion preparation, S. aureus   Abstrak Minyak sereh (Cymbopogon citratus (DC.) Stapf) dan minyak kemangi (Ocimum basilicum L.) adalah minyak esensial yang dapat dimanfaatkan sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri formulasi sediaan nanoemulsi kombinasi minyak sereh dan minyak kemangi terhadap bakteri S. aureus dan mengetahui konsentrasi yang efektif dari campuran keduanya. Kedua minyak yang digunakan diverivikasi meliputi analisis GC-MS, bobot jenis, indeks bias, kelarutan dalam alkohol serta bilangan asam. Formulasi sediaan nanoemulsi mengandung 4% (v/v) kombinasi minyak sereh dan minyak kemangi yang masing-masing fraksinya terdiri dari F1 (1:3), F2 (2:2) dan F3 (3:1). Sediaan yang dihasilkan diuji sifat fisik antara lain organoleptik, homogenitas, pH dan aktivitas antibakteri dengan menggunakan metode difusi sumuran. Hasil analisis GC-MS, minyak sereh memiliki komponen senyawa utama yaitu E-sitral (38,49%) dan Z-sitral (26,25%) sedangkan minyak kemangi senyawa utamanya yaitu Methyl chavicol (58,14%) dan linalool (31,72%). Evaluasi uji sifat fisik sediaan nanoemulsi minyak sereh dan minyak kemangi memenuhi parameter yang sesuai dengan standar. Dari hasil uji aktivitas antibakteri S. aureus F1 memiliki zona hambat sebesar 11,44 ± 2,51 mm, F2 18,89 ± 1,05 mm keduanya termasuk kategori kuat dan F3 23,78 ± 1,72 mm termasuk kategori sangat kuat. Kontrol positif mempunyai zona hambat 10,56 ± 0,53 mm dan kontrol negatif memiliki zona hambat 0 mm. Kesimpulannya, formulasi F3 sediaan deodoran roll on kombinasi minyak sereh dan minyak kemangi (3:1) sebanyak 4% memiliki aktivitas antibakteri terhadap bakteri S. aureus yang efektif. Kata Kunci:         Minyak sereh dan minyak kemangi, sediaan nanoemulsi, S. aureus
Co-Authors Abdul Fadlil Akrom, Akrom Ari Wahyudi Astuti, Febriana Capritasari, Rafiastiana Faikah Dyah Utami Hasan, Nuradnin Hasna, Elly Rosita Husain, Dewi Putri Iis Wahyuningsih Kintoko Lasanudin, Rindi Ibrahim Ma'ruf, Muhammad Mohamad Reski Manno Muhammad Yusron Maulana El-Yunusi Mustofa Mustofa Nuradnin Hasan Putri Purnamasari Putri, Meilisa Sapto Yuliani Sri Mulyaningsih Sri Mulyaningsih Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Yunda Maymanah Rahmadewi