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All Journal HAYATI Journal of Biosciences Microbiology Indonesia Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Communications in Science and Technology Jurnal Ilmu Kefarmasian Indonesia ASEAN Journal of Chemical Engineering International Journal of Social Service and Research Makara Journal of Technology Journal of Life Science and Technology
SAHLAN, MUHAMAD
Department Of Chemical Engineering, Faculty Of Engineering, Universitas Indonesia, Kampus UI Depok 16424, Indonesia. Research Center For Biomedical Engineering, Faculty Of Engineering, Universitas Indonesia, Kampus UI Depok 16424, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences

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Tooth spray with active ingredients casein phosphopeptide – amorphous calcium phosphate (CPP – ACP) and ethanolic extract propolis (EEP) to inhibit tooth demineralization Sahlan, Muhamad; Purwanti, Lucia
Communications in Science and Technology Vol 1 No 2 (2016)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.1.2.2016.24

Abstract

Dental caries is a disease caused by the microbial infection that produces localized damage to the tissue classification. The process begins by demineralization in hard tissue followed by damage to the organic material. Dental caries happens because of demineralization without balanced by remineralization. In this study, tooth powder spray and tooth liquid spray was made with active ingredients of 10% w/w CPP-ACP (Casein Phosphopeptide - Amorphous Calcium Phosphate) and EEP (Ethanolic Extract Propolis), with the variation of 0%, 2%, and 4% w/w EEP in each preparation to inhibit demineralization. Each preparation should pass organoleptic and viscosity study to maintain the quality. pH of each preparation was evaluated to ensure that each preparation has pH above the critical pH of the oral environment. The stability of polyphenol as the antibacterial agent was evaluated for a month to assure the bioavailability in the preparations. The result shows that each preparation has enough organoleptic aspect and proper viscosity. pH level in each preparation is stable above critical pH of mouth environment (5.5), it ranges between 6.5 – 7.12. Polyphenol content in each preparation is stable with highest polyphenol content in tooth powder spray of 4% EEP, i.e. 1.39 – 1.45% (w/w). Qualitative evaluation of tooth morphology by SEM shows that preparations can inhibit enamel demineralization relatively to negative control.
Antifungal activity of microcapsule propolis from Tetragonula spp. to Candida albicans Pratami, Diah Kartika; Indrawati, Teti; Istikomah, Iis; Farida, Siti; Pujianto, Paksi; Sahlan, Muhamad
Communications in Science and Technology Vol 5 No 1 (2020)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (591.231 KB) | DOI: 10.21924/cst.5.1.2020.178

Abstract

Propolis is a mixture of resin and saliva of Tetragonula spp. that have antifungal activity. The purpose of this study was to develop spray-dried microcapsule propolis (SDMP) and to analyze its antifungal activity to Candida albicans. The SDMP was obtained using a spray drying method by maltodextrin and gum arabic coating. The antifungal activity of SDMP of rough propolis (taken from the outside beehive) and smooth propolis (taken from the inside beehive) was analyzed. The macroscopic characterization showed that SDMP has a powder form with brownish-yellow color. The microscopic characterization showed SDMP has a spherical uniform particle shape with particle size 9.32 - 14.61 µm. The encapsulation efficiency of smooth and rough SDMP was 81.22% and 83.04%; moisture content 5.58% and 5.84%; water solubility 98.19% and 98.31%, respectively. The microbial inhibitory concentration to C. albicans was the diameter of 6.33±1.5 to 10±2.5 mm. SDMP displayed remarkable activity in the assays against C. albicans.
Evaluation of Honey Production for Industry Purposes, The Case of Beekeeping with Apis Mellifera in Indonesia After The Covid-19 Pandemic Purwanto, Didik B.; Kuntadi, Kuntadi; Adalina, Yelin; Meilin, Araz; Raffiudin, Rika; Sahlan, Muhamad
International Journal of Social Service and Research Vol. 4 No. 03 (2024): International Journal of Social Service and Research (IJSSR)
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v4i03.719

Abstract

The Indonesian beekeeping industry, grappling with diverse bee species, focuses on the sustainability of operations, particularly with the introduction of Apis mellifera during the early stages of the pandemic. This study explores post-pandemic Apis mellifera honey production in Indonesia, analyzing its impact on prices and business sustainability. Surveys and interviews were conducted with beekeepers in Java and Sumatra, primary islands with significant A. mellifera activities, along with data collection from other regions from January 2022 to October/November 2023. Monthly observations centered on honey production and prices for industrial purposes. The study uncovered two beekeeping systems: migratory in Java and stationery in Sumatra. Carpa honey from Accacia crassicarpa plantation emerged as a suitable industrial honey, displaying sustainable production, seasonality, and a large carpa area as bee forages, contributing to colony growth. Conversely, four Java honey types showed lower productivity, indicating a potential absence of honey seasons. Carpa honey prices ranged from IDR 25,200 to IDR 31,000 per kg, influenced by market size, production, competition, productivity, costs, and producer-consumer interactions. Despite a pandemic-induced surge in the honey market, sustaining high productivity and increasing colony numbers are crucial for long-term honey production sustainability.
CURRENT STATUS OF APIS MELLIFERA BEEKEEPING IN SUMATRA: TOWARD THE DEVELOPMENT OF INDONESIA'S HONEY INDUSTRY Purwanto, Didik B.; Purwantini, Tri Bastuti; Diana, Akso; Raffiudin, Rika; Sahlan, Muhamad
International Journal of Social Service and Research Vol. 5 No. 2 (2025): International Journal of Social Service and Research
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v5i2.1196

Abstract

Apis mellifera beekeeping in Sumatra has seen significant growth over the past decade, particularly since the COVID-19 pandemic began in early 2020, driven by high market demand for honey. Beekeeping activities are concentrated in Riau and Jambi provinces, where beekeepers primarily utilize extrafloral nectar from Acacia crassicarpa plantation forests. This study evaluates the current state of A. mellifera beekeeping in these regions, focusing on beekeeper proficiency and colony productivity. Data were collected through a survey of 42 beekeepers, addressing their characteristics, efforts to improve skills, perceptions of challenges, and colony productivity in 2024. The findings indicate that most beekeepers are young males aged 30–50 with secondary school education, managing between 100 and 500 hives despite limited knowledge. They primarily rely on self-directed learning and peer knowledge-sharing. Most beekeepers rated their apiaries as satisfactory but recognized their need for guidance to enhance productivity, ensure sustainability, and improve market access. In 2024, honey production averaged 25 kg per colony per year, or 2.1 kg per month, with Jambi slightly outperforming Riau (2.25 vs. 2.0 kg/colony/month). Honey prices averaged IDR 22,000/kg, with Riau prices higher (IDR 25,500-26,000/kg) than Jambi (IDR 19,800-20,300/kg). Sumatra is estimated to host around 250,000 A. mellifera colonies, contributing 92% to national honey output, compared to Java's 46,000 colonies and 8% of production.
Determination of the Kinetic Parameters of Cholesterol Oxidation using Cholesterol Oxidase from Streptomyces sp. Perdani, Meka Saima; Hermansyah, Heri; Sahlan, Muhamad; Putri, Dwini Normayulisa; Pambudi, Teguh; Hasibuan, Anggi Khairina Hanum
Makara Journal of Technology Vol. 28, No. 3
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cholesterol oxidase (CO) was successfully produced from Streptomyces sp. via the submerged fermentation method, and 69 U/mL enzyme activity was obtained. This study aimed to determine cholesterol oxidation kinetics and the production of CO as a catalyst. The enzyme was diluted to 0.15, 0.075, and 0.00375 U/mL for the oxidation reaction. The substrate was also prepared in three concentrations: 3.23, 6.46, and 12.93 mM. The optimization of conditions for enzymatic cholesterol oxidation was investigated through measurement of the effect of initial cholesterol and enzyme concentrations. Cholesterol concentration was rapidly measured via high-performance liquid chromatography (HPLC). The kinetics of CO were modeled using the first-order irreversible reaction. An enzymatic kinetic model was derived, and it was verified using experimental data and sensitivity analysis. Based on the experiment, the highest enzyme concentrations of crude and commercial CO can oxidize the substrate up to 84% within 240 min. However, the oxidation reaction showed a slightly different behavior in the early 60 min, and crude CO exhibited a slower substrate oxidation. The kinetic rate constant obtained by Euler’s method reached 1.0 x 10−3/min and 1.41 x 10−3/min for 0.15 U/mL crude and commercial CO, respectively.
Co-Authors Abdul Mun’im Adra Amalia Nur Ahlina Alya Fadhila Ismail AMARILA MALIK ANGGI KHAIRINA HANUM HASIBUAN Anondho Wijanarko Araz Meilin Asep Bayu Budiman Bela Christina, Diana Chulasiri, Malyn Deti Purwanti Diah Kartika Pratami Diana, Akso Dienayati, Dara Dwi Anggar Yusika Dwiranti, Astari Geraldine, Vanessa Hakamada, Kazuaki Hamdi, Darul Hanif Yuliani Hanifi, Muhammad Heri Hermansyah Hertanto, Robby Hiroshi Hashimoto Istikomah, Iis izzul islam Kamila, Etri Dian Kaysa Faradis Mahira Khayrani, Apriliana Cahya Kuntadi Kuntadi, Kuntadi Lischer, Kenny MUHAMMAD IQBAL Nadhifa Tazkia Ramadhani Nidaan Khafian Noguchi, Keiichi NUNUK WIDHYASTUTI Nur Elistiani Eksadita NURUL AZIZAH Perdani, Meka Saima Pujianto, Paksi Purwanti, Lucia Purwanto, Didik B. Putri, Dwini Normayulisa Putrika, Afiatry Ratna Yuniati RIKA RAFFIUDIN Ryo Miyata Sari Honda Sari, Siska Yuliana Satyapertiwi, Dwiantari Shigenori Kumazawa SISWA SETYAHADI Siti Farida Sri Rahayu, Amy Yayuk Sugiarta, Gede Yuda Teguh Pambudi Teti Indrawati TRI BASTUTI PURWANTINI Wiseso, Anggoro Yelin Adalina Yohda, Masafumi Yoshinobu Ishikawa YUKI DESIANDINI Zahra, Soraya