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All Journal Jurnal Kedokteran Syiah Kuala Indian Journal of Forensic Medicine & Toxicology Jurnal EduHealth
Linda Julisafrida
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Health Professions Medicine & Pharmacology Public Health Veterinary

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Nanoparticles-Based Face Masks and Respirators for Preventing COVID-19 Transmission: Breathability Versus Biocidal Activities Saminan Saminan; Linda Julisafrida; Sakdiah Sakdiah; Ratna Idayati; Nurul Fajri; Muhammad Iqhrammullah
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.15018

Abstract

Use of face masks and respirators are significant in preventing the transmission of coronavirus disease 2019(COVID-19) via respiratory droplets or aerosols. The development of face masks and respirators have beenfocused on the modification using nanoparticles (NPs) to obtain biocidal activities. The incorporation ofNPs can also increase the hydrophobicity of the material that assists the repelling of virus carrying dropletsor aerosols. Nevertheless, the common cost of gaining those benefits is breathability. Previous studies havereported on the discomforts of wearing a face mask or respirator, one of which is stems from breathingdifficulty. At the time of pandemic, maintaining the comfort wearing of face masks or respirators is evenmore crucial. Thus, this review article is important to keep the breathability aspect gaining a spotlight inthe development of NPs-modified face masks or respirators. Herein, we discuss the relationship betweenthe addition of NPs with breathability of the material. In the beginning of discussion, types of protectiverespiratory equipments, and biocidal activities of the modified fabrics are discussed. Strategies in maintainingthe air permeability for long duration use and self-cleansing feature are also discussed.
Peranan Immunoterapi Pada Kanker Paru Novita Andayani; Linda Julisafrida
Jurnal Kedokteran Syiah Kuala Vol 20, No 2 (2020): Volume 20 Nomor 2 Agustus 2020
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v20i2.18499

Abstract

Abstrak. Kanker paru masih menjadi masalah kesehatan secara menyeluruh, baik di dunia maupun di Indonesia, khususnya di Aceh. Saat ini kanker paru masih menjadi penyebab kematian tertinggi di dunia.  Berbagai peneletian tentang tatalaksana kanker paru telah dikembangkan, perkembangan terapi kanker paru saat ini berupa immunoterapi yang menargetkan reseptor penghambat sel T, seperti program sel death (PD-1) , terapi checkpoint blockade, immunoterapi baru berdasarkan neoantigen selektif dengan tujuan pengobatan mampu mendorong sel yang di transformasikan.Immunoterapi adalah salah satu metode pengobatan berbagai jenis tumor dengan efek samping yang dapat di atasi. Tujuan imunoterapi kanker adalah memberikan efektor antitumor (antibodi dan sel T ) terhadap pasien. Perkembangan ilmu pengetahuan tentang tatalaksana kanker berkembang sangat pesat, baik yang bersifat invasif maupun yang non invasif hingga penatalaksaan nano molekul. Tujuan pengobatan beruapa peningkatan kualitas hidup dan peningkatan survival rate.Kata Kunci : kanker paru, immunoterapi, PD-1, PD-L1, checkpoint blockadeAbstract. Lung cancer is still a comprehensive health problem, both in the world and in Indonesia, especially in Aceh. Currently lung cancer is still the highest cause of death in the world. Various studies on the management of lung cancer have been developed, the development of lung cancer therapy currently in the form of immunotherapy that targets T cell receptor inhibitors, such as the cell death program (PD-1), checkpoint blockade therapy, new immunotherapy based on selective neoantigens with the aim of treatment being able to encourage cells that transformed.Immunotherapy is one method of treating various types of tumors with side effects that can be overcome. The aim of cancer immunotherapy is to provide antitumor effectors (antibodies and T cells) to patients. The development of science about cancer management is developing very rapidly, both invasive and non-invasive to the management of nano molecules. Treatment goals include improving the quality of life and increasing survival rates.Keyword: lung cancer, immunotherapy, PD-1, PD-L1, checkpoint blockade
How Stress Influences The Physiological Functions Of The Human Body: A Bibliometric Mapping 2019-2024 Saminan, Saminan; Linda Julisafrida; Saminan, Nurul Fajri; Muhammad Khairul
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Abstract

Stress is an important component of modern life and has been widely recognized as a factor that negatively impacts health. The aim of this research is to map the influence of stress on the physiological functions of the human body over the last five years (2019–2024) using data from the Scopus database. Bibliometric analysis was conducted with VOSviewer visualization to depict publication patterns, citations, keywords, and relation-ships between concepts. The results indicate that the United States was the country with the highest number of publications in 2019, with 110 documents. Overall, the keywords "stress", "physiology", and "body" were the most frequently used. However, the topic of "hyper-thermia", a condition where the body temperature is higher than normal, has not been extensively re-searched. This study highlights the importance of un-derstanding in greater detail the mechanisms of the body's response to stress and identifying areas that re-quire further investigation, such as hyperthermia, to ef-fectively address the impact of stress on health.
The Effects of Smoking Habits and Emotional Stress on Sleep Quality Among Final-Year University Students Saminan, Saminan; Linda Julisafrida; Nurul Fajri Saminan; Muhammad Khairul
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

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Abstract

Final-year university students are particularly vulnerable to emotional stress due to academic pressure, the demands of completing a thesis, and anxiety about entering the workforce. In such circumstances, smoking is often used as a coping mechanism, although it may adversely affect sleep quality. This study aims to analyze the relationship between emotional stress, smoking habits, and sleep quality among final-year university students. This research employed a descriptive correlational design with a cross-sectional approach. The sample consisted of 50 final-year students selected through total sampling. Data collection instruments included the Kessler Psychological Distress Scale (K10) to assess emotional stress, a smoking habits questionnaire, and a sleep quality assessment via Google Forms. Data were analyzed using the Kendall Tau correlation test. The results showed a significant relationship between emotional stress and smoking habits (p<0.05), both of which were negatively correlated with sleep quality. Students with higher stress levels tended to smoke more frequently and experienced poorer sleep quality, including difficulty falling asleep and frequent nighttime awakenings. It can be concluded that emotional stress and smoking habits contribute to decreased sleep quality among students. Preventive interventions such as stress management education and smoking cessation efforts are essential to help maintain students' psychophysiological balance during the academic transition period.
Co-Authors . Saminan Iqhrammullah, Muhammad Muhammad Khairul Novita Andayani Nurul Fajri Nurul Fajri Saminan Nurul Fajri Saminan, Nurul Fajri Ratna Idayati Sakdiah Sakdiah Saminan Saminan