I Dewa Ayu Inten Dwi Primayanti
Bagian Ilmu Faal, Fakultas Kedokteran, Universitas Udayana

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Journal : BALI MEDICAL JOURNAL (BMJ)

IPOMOEA BATATAS SYRUP DECREASE MALONDIALDEHYDE AND INCREASE NITROUS OXIDE PLASMA LEVELS AMONGST MODERATE SMOKER WORKERS AT DENPASAR Dwi-Primayanti, I D. A. I.; Aman, I G. M.; Agus-Bagiada, N.
BALI MEDICAL JOURNAL Volume 1, Number 3, September-December 2012
Publisher : BALI MEDICAL JOURNAL

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Abstract

Objective: Cells and tissues are continuously damaged by reactive oxygen species. Cigarette smoke is one of an exogenous source of free radical containing more than 4000 chemical compounds, that triggering the formation of free radicals related to diseases and aging process. Anthocyanins are potent antioxidants that are widely distributed in fruit, vegetables, red wines and Ipomea batatas. The aim of this study was to determine the effect of Ipomea batatas as a source of antioxidants in decreasing levels of malondialdehyde (MDA) and increasing of Nitrous oxide (nitrite/nitrate/NOx) plasma in moderate smokers of workers at Denpasar. Method: This was an experimental study with a pretest-posttest control groups design. There are 33 moderate smokers who were divided into three groups, control group (placebo), treatment group with 15 ml purple sweet potato syrup (P1) and 30 ml (P2), for 14 days. All groups were performed the laboratory examinations for MDA and NOx plasma before and after the treatment. Results: This study showed that there were significant differences (p <0.05) both in MDA and NOx plasma levels in the control group, P1 and P2. The decrease of MDA levels on P1 was 35.39% and on P2 was 49.87%. The increase of NOx plasma levels was 7.78% for P1 and 14.68% for P2. Conclusion: From this study, it can be concluded that Ipomea batatas syrup contains of 8mg/mL anthocyanins, probably play a role in reducing the free radical and thus reducing the risk of disease and slowing the aging process.
Co-Authors AA Lanang Dananjaya Putra Dewa WA Ade Sugandhi Aditya Johan Romadhon Agung Ary Sutawinata Ali Imron Ari Wibawa Ayu Dilia Febriani Wisnawa Ayu Indriyani Utami AYU WULANDARI Azriel Siloam Bagus Komang Satriyasa Celine Setiawan Cindy Anastasia Okhotan Cindy Thiovany Soetomo Clara Ratu Angela Christi Darryl Rex Zaffyr Dewa Ayu Puspitasari Dewa Putu Gde Samatra Dewa Putu Gede Purwa Samatra Dio Septiyan Helmi Djuliana, Salsabila Fernanda Efraldo Yudistira Elvina Veronica Futi Nurul Destya Gede Dilajaya Robin Gusti Made Agung Mega Utama Hanik Nuryanti I Dewa Ayu Juniastari Putri I Dewa Putu Sutjana I G. M. Aman I Made Ady Wirawan I Made Jawi I Made Krisna Dinata I MADE MULIARTA . I Made Niko Winaya I Nengah Sandi I Nyoman Adi Putra I Nyoman Mangku Karmaya I Putu Adiartha Griadhi I Putu Gede Adiatmika I Wayan Gede Sutadarma I Wayan Weta I.G.N Bagus Hindra D Ida Ayu Dewi Wiryanthini Ida Ayu Priandini IGN Alit Hendra Wahyudi Indira Vidiari Juhanna Intan Ayu Puspaningsih J. A. Pangkahila Kadek Rina Agustinawati Ketut Tirtayasa Komang Diah Kurnia Kesumaputri Luh Gede Ayu Sri Nadi Wahyuni Luh Made Indah Sri Handari Luh Made Indah Sri Handari Luh Made Indah Sri Handari Adiputra Luh Putu Ratna Sundari Luh Putu Ratna Sundari M. Ali Imron Made Hendra Satria Nugraha Md Ayu Puspita Citra Novelia Moh Ali Imron Muh. Ali Imron Muhammad Irfan Munawwarah, Muthiah N. Agus-Bagiada Ni Kadek Ira Maharani Putri Ni Kadek Yuni Lestari Ni Ketut Dewita Putri Ni Luh Nopi Andayani Ni Made Dwi Dayanti Martini Ni Nyoman Arista Febrianti Ni Nyoman Ayu Dewi Ni Nyoman Ayu Dewi Ni Nyoman Nita Rosani Ni Putu Sukma Nathania Nur Basuki Nyoman Virna Uginiari Putu Andrie Setiawan Putu Astawa Putu Ayu Savitri Putu Ayu Sita Saraswati Putu Satriya Yudha Permadi Putu Satyakumara Upadhana Rahma Cempaka Putri Reza Fatchurahman Rizki Novrianti Santi Bery Hastuti Selviani, Iit Sugijanto - Susy Purnawati Syahmirza Indra Lesmana Virgilya S Wahyuddin, Wahyuddin Wardatun Nugraheni William Abraham S