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Kadar IgE Penderita Alergi pada Mahasiswa Teknologi Laboratorium Medik Universitas Muhammadiyah Purwokerto Tantri Analisawati Sudarsono; Dita Pratiwi Kusuma Wardani; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol 6 No 2 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i2.1952

The prevalence of allergies is increasing from year to year due to the modern lifestyle in society. The incidence of allergies was influenced by several factors, such as genetics, age, sex, diet, food type, and also environmental factors. Determination of IgE levels in adolescents and young adults is important because the incidence of allergy is highly reported in adolescents and young adults. This study was conducted to determine IgE levels in allergies among university students in Universitas Muhammadiyah Purwokerto. This observational study was conducted among diploma students of Medical Laboratory Technology, Universitas Muhammadiyah Purwokerto. The data of characteristic subjects were collected by a self-administered questionnaire whereas data of IgE levels were collected by serum samples and measured by ELISA. A total of 23 students (4.35 % male and 95.65% female) were included. Seafood allergy (25%) were the commonest allergy among the students. Only 9% of subjects have combination allergies. The highest of IgE levels were 365 IU/mL.

Perbandingan Hasil Pemeriksaan Hitung Jumlah Eritrosit Menggunakan EDTA Konvensional dan Vacutainer Lilis Septiana Dewi; Tantri Analisawati Sudarsono; Retno Sulistiyowati
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.2842

Hematology examination in practice often uses anticoagulants to prevent clotting in blood samples, including in the examination of the erythrocyte count. The anticoagulant that is often used for examination is EDTA (Ethylene Diamine Tetra Acetic Acid). With the changing times, the addition of anticoagulants to the examination is no longer done conventionally but is already contained in the vacutainer tube. However, the vacutainer anticoagulant cannot be adjusted to the blood volume obtained during phlebotomy, while the conventional anticoagulant can be added according to the blood volume obtained. This research is a pre-experimental research design with a One-Shot Case Study design, in which each blood sample is added with conventional anticoagulants and vacutainers. The method used is manual using a hemocytometer and a microscope. Analysis of the data using the Independent T-test. The purpose of this study was to find out the comparison of the results of the erythrocyte count using conventional EDTA and a vacutainer. After examination with both anticoagulants, p-value = 0.822 (p>0.05) so there is no comparison. Based on these results, it can be concluded that there is no comparison of erythrocyte count examination using conventional EDTA and vacutainer.

Hubungan Kadar C Reactive Protein dengan Jumlah Neutrofil Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 6 Bulan di BKPM Purwokerto Nadia Ega Haliza; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol 8 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3480

Tuberkulosis merupakan penyakit yang disebabkan oleh Mycobacterium tuberculosis yang menyerang organ paru. Adanya peradangan Tuberculosis didalam tubuh ditandai dengan respon inflamasi. Respon inflamasi didalam tubuh dapat didiagnosa melalui pemeriksaan C Reactive Protein sebagai respon anti infeksi imun didalam tubuh seseorang. Biasanya adanya peningkatan kadar C Reactive Protein mengindikasikan infeksi yang tidak terkontrol. Selain pemeriksaan tersebut, pemeriksaan penanda lainnya dapat dilihat dari pemeriksaan hematologi seperti hitung jenis neutrofil. Tujuan penelitian ini untuk mengetahui hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan di BKPM Kabupaten Banyumas. Penelitian ini menggunakan metode observasional analitik dengan rancangan Cross-sectional. Kemudian sampel dalam penelitian ini sebanyak 30 pasien tuberkulosis paru yang terdiri dari pasien fase pengobatan 0 dan 6 bulan. Terdapat hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan (p = 0,014, r= 0,370)

Hubungan Kadar C-Reactive Protein dengan Jumlah Leukosit Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 2 Bulan di BKPM Purwokerto Syafira Dian Ergiana; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol 8 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3482

Pulmonary tuberculosis is still a health problem to control in the world. This disease is caused by the bacterium Mycobacterium tuberculosis, which can cause inflammation that can trigger increased levels of C-Reactive Protein and leukocytes in the body. This study was conducted to determine the correlation between C-Reactive Protein levels and the number of leukocytes with treatment phases 0 and 2 months in BKPM Purwokerto. The design of this study was an analytical observation with a cross-sectional research design. Results from 30 pulmonary tuberculosis patients treated for 0 and 2 months showed a correlation between CRP levels and white blood cell counts (p = 0.002, r = 0.445). There is a moderate relationship between CRP levels and leukocyte counts. High levels of CRP correlate with increasing the number of leukocytes. More research is needed on the relationship between CRP levels and leukocyte counts with different phases of treatment.

Hubungan Kadar C Reactive Protein dengan Jumlah Neutrofil Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 6 Bulan di BKPM Purwokerto: Relationship Between C Reactive Protein Levels and the Number of Neutrophils in Pulmonary Tuberculosis Patients with Phases 0 and 6 Months at BKPM Purwokerto Nadia Ega Haliza; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol. 8 No. 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3480

Tuberkulosis merupakan penyakit yang disebabkan oleh Mycobacterium tuberculosis yang menyerang organ paru. Adanya peradangan Tuberculosis didalam tubuh ditandai dengan respon inflamasi. Respon inflamasi didalam tubuh dapat didiagnosa melalui pemeriksaan C Reactive Protein sebagai respon anti infeksi imun didalam tubuh seseorang. Biasanya adanya peningkatan kadar C Reactive Protein mengindikasikan infeksi yang tidak terkontrol. Selain pemeriksaan tersebut, pemeriksaan penanda lainnya dapat dilihat dari pemeriksaan hematologi seperti hitung jenis neutrofil. Tujuan penelitian ini untuk mengetahui hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan di BKPM Kabupaten Banyumas. Penelitian ini menggunakan metode observasional analitik dengan rancangan Cross-sectional. Kemudian sampel dalam penelitian ini sebanyak 30 pasien tuberkulosis paru yang terdiri dari pasien fase pengobatan 0 dan 6 bulan. Terdapat hubungan kadar C Reactive Protein dengan jumlah neutrofil pada penderita tuberkulosis paru dengan fase pengobatan 0 dan 6 bulan (p = 0,014, r= 0,370)

Hubungan Kadar C-Reactive Protein dengan Jumlah Leukosit Penderita Tuberkulosis Paru pada Fase Pengobatan 0 dan 2 Bulan di BKPM Purwokerto Syafira Dian Ergiana; Dita Pratiwi Kusuma Wardani; Tantri Analisawati Sudarsono; Arif Mulyanto
Jurnal Surya Medika (JSM) Vol. 8 No. 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i2.3482

Pulmonary tuberculosis is still a health problem to control in the world. This disease is caused by the bacterium Mycobacterium tuberculosis, which can cause inflammation that can trigger increased levels of C-Reactive Protein and leukocytes in the body. This study was conducted to determine the correlation between C-Reactive Protein levels and the number of leukocytes with treatment phases 0 and 2 months in BKPM Purwokerto. The design of this study was an analytical observation with a cross-sectional research design. Results from 30 pulmonary tuberculosis patients treated for 0 and 2 months showed a correlation between CRP levels and white blood cell counts (p = 0.002, r = 0.445). There is a moderate relationship between CRP levels and leukocyte counts. High levels of CRP correlate with increasing the number of leukocytes. More research is needed on the relationship between CRP levels and leukocyte counts with different phases of treatment.

Hubungan Kepemilikan Jamban dengan Kejadian Diare di Desa Bagan Laguh, Kecamatan Bunut, Riau: The Correlation Between Toilet Ownership With the Event of Diarrhea in Bagan Laguh Village, Bunut Sub-District, Riau Nur Rizki Aprilia Utami; Tantri Analisawati Sudarsono; Retno Sulistiyowati; Supriyadi Supriyadi
Jurnal Surya Medika (JSM) Vol. 9 No. 1 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i1.5164

Diarrhea is an endemic disease that can cause Extraordinary Events (KLB). In 2017, there were 21 occurrences of diarrhea spreading across 12 provinces with a total of 1,725 patients and 34 deaths (CFR 1.97%). There are three risk factors for diarrhea, namely individual characteristics, preventive behavior, and environment. This research is to determine the correlation between toilet ownership and the occurrence of diarrhea in Bagan Laguh Village, Riau. The research population was all residents of Bagan Laguh Village listedin the Integrated Social Welfare Data (DTKS) and 59 residents were selected as the research sample using the simple random sampling technique. The primary data were obtained from the questionnaires filled out by the respondents and then analyzed using the Chi-Square test. The results of this research indicated that respondents' level of education and income are not significantly correlated with the occurrence of diarrhea(P values= 0.115 and 0.421 respectively); however, respondents' knowledge, attitude, and toilet ownership are correlated with the occurrence of diarrhea significantly (P-values = 0.007, 0.001, and 0.002 respectively).

Perbandingan Kadar HB Sebelum dan Sesudah Pengobatan Oat Fase Intensif pada Penderita Tuberkulosis Paru di Puskesmas Petanahan Kebumen Tahun 2021: The Comparison of Hemoglobin Levels Between Before and After Treatment of Intensive Phase of Anti-Tuberculosis Drug in Pulmonary Tuberculosis Patients of Petanahan Public Health Care Center, Kebumen Regency Evi Nurhayati; Arif Mulyanto; Tantri Analisawati Sudarsono; Linda Wijaya
Jurnal Surya Medika (JSM) Vol. 9 No. 1 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i1.5192

Treatment of tuberculosis with main anti-tuberculosis drugs (OAT) includes isoniazid (INH), rifampin (RIF), ethambutanol (EMB), streptomycin (SM), and pyrazinamide (PZA). Although most Anti-Tuberculosis Drugs (OAT) are acceptable in therapy, they have potential side effects, including the side effects of hematological reactions such as anemia. This study's purpose was to compare HB levels before and after the intensive phase of Anti-Tuberculosis Drugs treatment in TB patients at Petanahan Public Health Care Center, Kebumen Regency. This was an analytic observational study with a cross-sectional design. The sample in this study was 28 people. The result showed that the average Hb level of pulmonary TB patients at Petanahan Public Health Care Center before and after the treatment were 11.05 g/dl and 11.6 g/dl, respectively. Therefore there was an effect of comparing Hb levels before and after the intensive phase of Anti-Tuberculosis Drugs treatment in pulmonary TB patients at the Petanahan Public Health Center in 2021. The increase in the average Hb levels of patients with pulmonary TB before and after the treatment was 0.55. The sig values obtained from the analysis of Hb levels before and after the treatment were a = 0.200 (p0.005) and 0.023, respectively. Due to the P value (0.023 < 0.05), Ho was rejected. It meant that there was a difference in Hb levels before and after the Intensive Phase of Anti-Tuberculosis Drugs treatment in patients with pulmonary TB at Petanahan Public Health Care Center, Kebumen Regency.

Literature Review: Hubungan Kadar D-Dimer dengan Tingkat Keparahan Pasien Covid-19: Literature Review: The Relationship of D-Dimer Levels with the Sverity of Covid-19 Ismi Andina Pertiwi; Tantri Analisawati Sudarsono; Dita Pratiwi Kusuma Wardani; Minto Rahaju
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5726

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) causes Corona Virus Disease-19 (COVID-19). D-dimer is one of the hemostasis tests performed on patients infected with the disease, it is a product of fibrin degradation and a biomarker of platelet disorders. With the development of COVID-19 as a pandemic, D-dimer has become an indicator for prognosis in COVID-19 patients. Based on symptoms, the severity of COVID-19 patients consists of mild, moderate, and severe symptoms. The author conducted a literature review regarding the correlation between D-dimer levels and the severity of COVID-19 patients. Data and theory were taken from ten references from several databases: Google Scholar, PubMed, Semantic Scholar, Science Direct, Garuda, and Neliti. The references taken were from the 2020-2022 range. In all of these references, statistical test results were obtained with a significant value below 0.05, so it can be concluded that there is a correlation between D-dimer levels and the severity of COVID-19. In COVID-19 infections with severe symptoms, immunothrombosis can occur due to hyperinflammatory conditions and cytokine storms. Immunothrombosis occurs as a result of the body's defense against viral infections. Damage to lung tissue in COVID-19 patients triggers a procoagulant response associated with inflammatory cytokines in blood vessel tissue.

Pengaruh Pemberian Obat Anti Tuberkulosisi (OAT) Terhadap Jumlah Trombosit pada Pasien TB Paru di BKPM Purwokerto: The Effect of Anti Tuberkulosis Drug (OAT) Towards the Number of Pulmonary TB Patients at BKPM Purwokerto Ika Wulan Nuri Anggreani; Tantri Analisawati Sudarsono; Dita Pratiwi Kusuma Wardani; Minto Rahaju
Jurnal Surya Medika (JSM) Vol. 9 No. 2 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i2.5727

Pulmonary tuberculosis (TB) is an infection of the lungs characterized by pulmonary infiltrates and the formation of caseous granulomas, fibrosis, and cavities. It can be caused by the risk of transmission of the acid-fast bacillus Mycobacterium tuberculosis. One supportive treatment for pulmonary TB is the administration of anti-tuberculosis drugs (OAT). The content of rifampicin in the anti-tuberculosis drug can cause side effects of hemorrhagic disorders, namely thrombocytopenia. This study aims to determine the effect of giving OAT on platelet counts in TB patients in treatment phases of 0, 2, and 6 months at BKPM Purwokerto (Balai Kesehatan Paru Masyarakat). This was a type of analytic observational study with a cross-sectional design. Patients with pulmonary TB in treatment phase 0 were 15 at two months and 15 at six months in this study. Sampling was carried out by purposive sampling with inclusion and exclusion criteria. From this analysis, it is known that the data used the one-way ANOVA test. The results obtained have a p-value of 0.101 (p 0.05), so it can be concluded that there is no effect of the administration of OAT on platelet counts in TB patients in the treatment phases of 0, 2, and 6 months.

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