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Antituberculosis Activity Test of N-p-Methylbenzyl-p-coumaramide (MBC) Against M. tuberculosis H37Rv Nasriadi Dali Wela; Arniah Dali Wela; Seniwati Dali; Hilda Ayu Melvi Amalia
Al-Kimia Vol 8 No 2 (2020): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v8i2.10761

Abstract

An antituberculosis activity test of N-p-Methylbenzyl-p-coumaramide (MBC) against M. tuberculosis H37Rv has been carried out. The purpose of this study was to determine the antituberculosis activity of MBC against M. tuberculosis H37Rv. The study was conducted using agar diffusion method. The test solution was prepared by dissolving MBC in 20 mL Ogawa medium to a final concentration of 0.25; 0.50; 1; and 2 mg/L. PDA media that had been inoculated with M. tuberculosis H37Rv (seeded agar) were poured over the base layer on the petridish surface. Paper disks that have been immersed in the test solution were put symmetrically on the seeded agar. Furthermore, the seeds were incubated at 37 oC for 48 hours. Then the diameter of the inhibition zone was measured to the accuracy of 0.5 mm with a ruler. The results showed that MBC has biological activity as an antituberculosis. MBC can inhibit the growth of M. tuberculosis H37Rv at a concentration of 0.25; 0.50; 1; and 2 mg/L with a diameter of inhibitory zones respectively 8.9; 13.7; 18.5; and 21.3 mm. This showed that the inhibition of MBC on the growth of M. tuberculosis H37Rv increased with increasing concentration of MBC used.
Pengaruh Model Problem Based Learning Terhadap Hasil Belajar Siswa pada Materi Sistem Imun di SMA Negeri 6 Kendari Hilda Ayu Melvi Amalia; Siti Raoda; Muhammad Syarwa Sangila; Hadi Machmud; Samrin Samrin
KULIDAWA Vol 1, No 1 (2020): Mei
Publisher : IAIN Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31332/kd.v1i1.1805

Abstract

Artikel ini bertujuan untuk mengetahui pengaruh hasil belajar kognitif siswa sesudah diajar dengan menggunakan model problem based learning pada materi sistem imun di SMA Negeri 6 Kendari. Jenis penelitian ini ialah penelitian kuantitatif, dengan metode penelitian quasi eksperimen. Teknik analisis data dilakukan dengan menggunakan analisis deskriptif dan analisis inferensial. Sampel pada penelitian ini yaitu kelas XI MIPA 5 (kelas eksperimen) dan kelas XI MIPA 6 (kelas kontrol), masing-masing sebanyak 20 siswa. Teknik pengambilan sampel dilakukan dengan menggunakan teknik purposive sampling. Hasil penelitian menunjukkan bahwa terdapat perbedaan yang signifikan antara hasil belajar kognitif siswa sesudah diajar menggunakan model problem based learning dan sesudah diajar menggunakan model konvensional pada materi sistem imun di SMA Negeri 6 Kendari, yaitu thitung 5,31 dan ttabel1,67 dengan taraf signifikansi 5%, sehingga thitung 5,31 > ttabel1,67 maka H0 ditolakdan Ha diterima.Kata Kunci: Hasil Belajar Kognitif, Model Problem Based Learning, Model Konvensional.
Synthesis of the BEAC4ND4 Ionophore from p-t-Butylcalix[4]arene Carboxylic Acid Nasriadi Dali; Arniah Dali; Seniwati Dali; Hilda Ayu Melvi Amalia
Jurnal Kimia Sains dan Aplikasi Vol 23, No 12 (2020): Volume 23 Issue 12 Year 2020
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3261.582 KB) | DOI: 10.14710/jksa.23.12.424-431

Abstract

The BEAC4ND4 ionophore has been successfully synthesized from p-t-butylcalix[4]arene carboxylic acid. The BEAC4ND4 ionophore was obtained in two steps of the synthesis reaction. The first step is the chlorination reaction of p-t-butylcalix[4]arene carboxylic acid with thionyl chloride in dry benzene solvent. The chlorination reaction product is p-t-butylcalix[4]arene acyl chloride in the form of the light brown viscous liquid with a yield of 78.25% and TLC (SiO2, CH3OH: CH2Cl2 = 1: 1 v/v, Rf = 0.65). The second step is the amidation reaction of ethyl 2-aminoacetate with p-t-butylcalix[4]arene acyl chloride in dry tetrahydrofuran solvent. The product of the amidation reaction is p-t-butylcalix[4]arene ethylesteramide or the BEAC4ND4 ionophore in the form of a white solid with the yield of 75.22%, a melting point of 314-316°C, and TLC (SiO2, CH3OH: CH2Cl2 = 1: 1 v/v, Rf = 0.75).
Highly Selective and Sensitive Determination of Hg(II) Ions Using Ion Selective Electrodes (ISE) Coated with the BEC4ND1 Ionophore as Membranes Nasriadi Dali; Seniwati Dali; Armadi Chairunnas; Hilda Ayu Melvi Amalia; Sri Ayu Andini Puspitasari
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 7, No 2 (2022): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v7i2.62213

Abstract

The research on the highly selective and sensitive determination of Hg(II) ions using ion-selective electrodes (ISE) coated with the BEC4ND1 ionophore as a membrane has been successfully carried out. ISE was designed using the membrane composition of the [(BEC4ND1 ionophore : PTCPB : DOS : PVC) (3 : 2 : 60 : 35 % w/w)]. The ESI-BEC4ND1 ionophore has good characteristics where it shows a sensitivity value of 29.933 mV/decade in the Hg(II) ion concentration range of 10-9 - 10-1 M with a limit of detection (LoD) of 10-7 M. The response time obtained is in the range of 4 - 8 minutes with a relative standard deviation (RSD) of 0.548. The ESI-BEC4ND1 ionophore also shows the average value of selectivity coefficient (Kij) < 1. These results indicate that the presence of Zn(II), Cd(II), and Pb(II) ions as interfering ions in the analyte solution does not affect the performance of the ESI-BEC4ND1 ionophore in detecting Hg(II) ions. The ESI-BEC4ND1 ionophore that has been developed shows good selectivity, sensitivity, stability, and reproducibility, so the ESI-BEC4ND1 ionophore is promising to be used as a Hg(II) ion detector in the environment.
Antifungal Activity Test of the Ethanol Extract of Kaembu-embu (Blumea balsamifera) Leaves Against the Fungus C. albicans Growth Nasriadi Dali Wela; Arniah Dali Wela; Seniwati Dali; Armadi Chairunnas; Hilda Ayu Melvi Amalia; Sri Ayu Andini Puspitasari
ALCHEMY:Journal of Chemistry Vol 10, No 2 (2022): ALCHEMY: Journal of Chemistry
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v10i2.10954

Abstract

AbstractResearch on the antifungal activity test of ethanol extract of Kaembu-embu (Blumea balsamifera) leaves against the fungus C. albicans growth was carried out. The aim of this study was to examine the antifungal activity of ethanol extracts of Kaembu-embu (Blumea balsamifera) leaves on the growth of the fungus C. albicans. The ethanol extract of Kaembu-embu (Blumea balsamifera) leaves was obtained through maceration method. The ethanol extract of Kaembu-embu (Blumea balsamifera) leaves was tested for antifungal activity by liquid and solid dilution methods in determining minimum inhibitory concentration (MIC) and minimum kill concentration (MKC). The results of the antifungal activity of the ethanol extract of Kaembu-embu (Blumea balsamifera) leaves on the growth of the fungus C. albicans by the liquid dilution method showed the MIC value of 25 ppm and MKC value of 500 ppm. While the results of the antifungal activity of the ethanol extract of Kaembu-embu (Blumea balsamifera) leaves on the growth of the fungus C. albicans by solid dilution method showed the MIC value of 5 ppm with inhibitory ability of 50.13% of media control and a MKC value of 250 ppm.
Pretreatment of Used Cooking Oil Using Avocado Seed Adsorbent for Biodiesel Production Preparation Nasriadi Dali; Seniwati Dali; Armadi Chairunnas; Hilda Ayu Melvi Amalia; Sri Ayu Andini Puspitasari
METANA Vol 19, No 1 (2023): Juni 2023
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/metana.v19i1.51797

Abstract

Used cooking oil (UCO) can be used as raw material for biodiesel production, but its free fatty acid (FFA) content is still quite high, so it is necessary to do pretreatment in the form of an adsorption process to reduce FFA levels. This study aims to determine the optimum conditions for the adsorption process and determine FFA levels of UCO before and after pretreatment. The adsorbent used is avocado seed activated charcoal, because it has a surface area of 19.62 m2/g. The larger the surface area of the adsorbent material, the greater the adsorption capacity of the adsorbent. Optimization of the UCO adsorption process includes variations in adsorbent mass (6, 8, 10 g), adsorbent particle size (60, 100, 140 mesh), contact time (2, 6, 10 hours), and temperature (60, 80, 100oC). The results showed that the optimum conditions for adsorption of UCO were obtained at mass (10 g), particle size (100 mesh), contact time (6 h), and temperature (80oC). This condition can reduce the FFA content of UCO by 71.64% (w/w), from 5.29% (w/w) to 1.50% (w/w). The FFA content of UCO [1.50% (w/w)] produced after pretreatment was qualified as a raw material for the preparation of biodiesel production through the transesterification stage.
Phytoremediation of nickel by Paraserianthes falcataria with varying levels of manure Hilda Ayu Melvi Amalia; Armadi Chairunnas; Andhika Puspito Nugroho
Jurnal Biolokus Vol 6, No 1 (2023): June
Publisher : Universitas Islam Negeri Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30821/biolokus.v6i1.2118

Abstract

The objective of this study were to identify effective variations in fertilizer doses for phytoremediation of heavy metal nickel (Ni) by using sengon plants (Paraserianthes falcataria) before being used for post-mining land reclamation. This research is an experimental study, the growth parameters measured include plant height, number of leaves, root length, and plant biomass. The data obtained were analyzed using analysis of variance (ANOVA) and continued with Duncan's test. The manure used consists of chicken manure, calcium carbonate, and rice bran. Variation in fertilizer dose is the ratio between manure to mine soil 40:60 (A), 50:50 (B), 60:40 (C), 70:30 (D), and control without fertilizer (E) with four repetitions time. The results showed that there was a significant difference between the concentration of nickel content before and after the treatment of fertilizer dosing (p>0.05), which means that the dose of fertilizer can affect plant growth and phytoremediation abilities. The dose of D fertilizer (70:30) is the most suitable for phytoremediation of heavy metal nickel (Ni) because it shows the highest heavy metal concentration in the roots, which is 3.2 ppm. The plant growth parameters measured showed that the dose of fertilizer B (50:50) was most suitable for increasing plant height and biomass (P. falcataria) with a plant height of 27 cm and a biomass of 0.9 g/m2. The dose of C fertilizer (60:40) is most suitable for increasing the number of leaves with an average of 111.5 leaves. Control without fertilizer (E) is most suitable for increasing the root length of P. falcataria. Thus, the addition of manure affects the growth of P. falcataria, and nickel phytoremediation using P. falcataria at the dose of manure D (70:30) can reduce the nickel content in the soil.
Synthesis of Ionophore from p-t-Butyl-(carboxymethoxy)calix[4]arene Substituted Amide Nasriadi Dali; Seniwati Dali; Armadi Chairunnas; Hilda Ayu Melvi Amalia; Sri Ayu Andini Puspitasari
Molekul Vol 18 No 1 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.1.5927

Abstract

The ionophore has been successfully synthesized from p-t-butyl(carboxymethoxy)calix[4]arene subtituted amide. The ionophore was obtained in two steps of the synthesis reaction. The first step is the chlorination reaction of p-t-butyl(carboxymethoxy)calix[4]arene with thionyl chloride in dry benzene solvent. The product of the chlorination reaction is p-t-butyl(chloroacetylmethoxy)calix[4]arene in the form of the light brown viscous liquid with the rendemen of 78.25% and TLC (SiO2, CH3OH : CH2Cl2 = 1 : 1 v/v, Rf = 0.65). The second step is the amidation reaction of p-t-butyl(chloroacetylmethoxy) calix[4]arene with dimethylamine in dry tetrahydrofuran solvent. The product of the amidation reaction is p-t-butyl(dimethylcarbamoylmethoxy)-calix[4]arene or the DIMECAC4ND3 ionophore in the form of white solid with the rendemen of 60.75%, a melting point of 277-279 °C, and TLC (SiO2, CH3OH : CH2Cl2 = 1 : 1 v/v, Rf = 0.82).
POLA PERTUMBUHAN DAN KEANEKARAGAMAN GASTROPODA PADA EKOSISTEM MANGROVE DI KONAWE SELATAN, INDONESIA Sri Ayu Ningsih; Armadi Chairunnas; Hilda Ayu Melvi Amalia; Agusrinal Agusrinal; Samsi Burhan; Aqmal Khaery
Biokatalis : Jurnal Ilmu Biologi dan Pendidikan Biologi Vol. 1 No. 1 (2024): TERBITAN JANUARI
Publisher : LPPM UNIVERSITAS NAHDLATUL ULAMA SULAWESI TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69972/biokatalis.v1i1.27

Abstract

Hutan mangrove adalah sebutan untuk sekelompok tumbuhan yang hidup di daerah pasang surut pantai. Hutan mangrove dikenal juga dengan sebutan hutan payau.  Desa Akuni yang disebabkan oleh aktifitas masyarakat dengan mengekploitasi hutan untuk dijadikan lahan pertambakan serta pemanfaatan pohon dari jenis mangrove sebagai bahan bakar atau perabot rumah tangga sehingga terjadi kerusakan atau terdegradasinya hutan mangrove tersebut. Penelitian ini bertujuan untuk mengetahui pola pertumbuhan dan keanekaragaman gastropoda pada ekosistem mangrove di konawe selatan.  Alat-alat yang digunakan pada penelitian ini antara lain termometer, hand refractometer, GPS, kantong sampel (cool box), parang, patok kayu, meteran roll, tali rafia, soil tester, kamera digital, pH meter, timbangan Ohaus, Vernier Caliper, oven, dan tanur. Bahan-bahan yang digunan dalam penelitian ini yaitu gastropoda, alkohol 70%, aquades, sampel air laut, serta sedimen. Pengambilan sampel gastropoda dilakukan pada saat air surut dengan membuat plot berukuran 20x20 sebanyak 2 buah. Sampel gastropoda diidentifikasi di Laboratorium Ekologi dan Taksonomi Jurusan Biologi FMIPA Unhalu. Parameter lingkungan yang diukur antara lain suhu, salinitas, pH, dan KOT. Analisis data menggunakan rumus BT = a(PC)b. Hasil penelitian menunjukkan Gastropoda yang ditemukan di desa Akuni adalah10 jenis. Tipe substrat pada plot 1 adalah pasir berlumpur. Hasil analisis regresi menunjukkan gastropoda yang ditemukan pada plot 1 dan 2 di desa Akuni termasuk kedalam pola pertumbuhan alometrik negatif (b<3)
Persepsi Siswa Terhadap Keterampilan Mengajar Guru Biologi di Madrasah Aliyah Darul Mukhlisin Nisra Nisra; Masdin Masdin; Hilda Ayu Melvi Amalia; Balda Balda
Biokatalis : Jurnal Ilmu Biologi dan Pendidikan Biologi Vol. 1 No. 2 (2024): TERBITAN JUNI
Publisher : LPPM UNIVERSITAS NAHDLATUL ULAMA SULAWESI TENGGARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69972/biokatalis.v1i2.112

Abstract

Penelitian ini bertujuan untuk: 1) Untuk mengetahui keterampilan mengajar guru biologi. 2) Untuk mengetahui persepsi siswa terhadap keterampilan mengajar guru biologi. 3) Untuk mengetahui dampak persepsi siswa terhadap hasil pembelajaran tentang keterampilan mengajar guru biologi di Madrasah Aliayah Darul Mukhlisin. Penelitian ini menggunakan pendekatan kualitatif dengan metode yang bersifat deskriptif. Sumber data dalam penelitian ini dibedakan menjadi dua yaitu sumber data primer dan sumber data sekunder. Hasil dari penelitian ini menunjukkan bahwa: 1) Keterampilan mengajar guru biologi di Madrasah Aliyah Darul Mukhlisin dari delapan keterampilan mengajar yang sering digunakan hanya empat yaitu, keterampilan membuka dan menutup pelajaran, keterampilan menjelaskan, keterampilan bertanya, dan keterampilan mengelola kelas. 2)Persepsi siswa terhadap keterampilan mengajar guru biologi di Madrasah Aliyah Darul Mukhlisin menunjukkan terdapatenam keterampilan yang masuk dalam kategori baik seperti keterampilan membuka dan menutup pelajaran, keterampilan menjelaskan, keterampilan bertanya, keterampilan mengadakan variasi, keterampilan membimbing diskusi kelompok kecil dan keterampilan mengelola kelas sedangkan terdapat dua keterampilan yang kurang baik seperti keterampilan memberikan penguatan dan keterampilan mengajar kelompok kecil dan perorangan. 3) Dampak persepsi siswa terhadap hasil pembelajaran tentang keterampilan mengajar guru biologi di Madrasah Aliyah Darul Mukhlisin yaitu memiliki dampak pada hasil belajar siswa yang dapat ditunjukkan dari hasil nilai ulangan bahwa terdapat 19 siswa nilai ulangan rendah dari 59 siswa. Bisa dikatakan bahwa perlunya seorang guru menerapkan beberapa keterampilan mengajar agar mempermudah siswa untuk memahami materi yang dibawakan oleh guru dan perlu mendengarkan persepsi siswa agar mengetahui seberapa paham siswa tentang materi yang diajarkan.