Nina Handayani
Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Brawijaya

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PREVALENSI DEPRESI DAN GAMBARAN STRESSOR PSIKOLOSOSIAL PADA REMAJA SEKOLAH MENENGAH UMUM DI WILAYAH KOTAMADYA MALANG Asmika, Asmika; Harijanto, Harijanto; Handayani, Nina
Jurnal Kedokteran Brawijaya Vol 24, No 1 (2008)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (106.959 KB) | DOI: 10.21776/ub.jkb.2008.024.01.2

Abstract

During the mental development process, the adolescent will be exposed tonumerous events that might act as psychosocial stressors. These stressors might contribute to the prevalence of depression in adolescent. This study aimed to determine the prevalence of depression description of psychosocial stressor, and the relationship between psychosocial stressors and depression in adolescent. A cross sectional descriptive analytic study was conducted using 458 particiapants from three representative Senior High Schools in Malang district. The depression level was measured  using Beck Depression Inventory while Holmes and Rahe Stress Scale for Youth was used to mesure the  level of psychosocial stressor. It was found that prevalence of depression were as follows 32,5% of respondents with mild depression; 28,2% with moderate depression; and the remaining 11,1% withsevere depression. Of all particiapants, 59,6% experience a high level stressor, while the other 40,4% have low level stressor. The study identify a significant correlation (p<0.001)between depression level and level of psychosocial stressor. . The risk of having depression is 5.87 higher in respondents with high level of psychosocial stressor compare to those with low level psychosocial stressor (OR=5.87). Therefore, a cooperation between school, community and parent is highly advised toprovide a favourable environment for mental development in adolescent. In addition parents, school need to prepare the adolescent in order to anticipate numeros events that influence their mental health.
HUBUNGAN KADAR HBA1C DENGAN REACTIVE OXYGEN SPECIES DALAM SERUM DARAH DAN GRADASI KATARAK PADA PASIEN KATARAK DENGAN DIABETES MELITUS Handayani, Nina; Trifena, Pasenggo; Vierlia, Wino Vrieda
Majalah Kesehatan FKUB Vol 7, No 2 (2020): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (380.591 KB) | DOI: 10.21776/ub.majalahkesehatan.2020.07.02.1

Abstract

Katarak merupakan suatu kelainan yang ditandai dengan adanya kekeruhan pada lensa mata. Selain karena penuaan, faktor lain yang terlibat dalam pembentukan katarak adalah diabetes melitus. Kondisi hiperglikemia berasosiasi dengan stres oksidatif yang berperan dalam proses pembentukan katarak. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar HbA1C dengan reactive oxygen species (ROS) dalam serum darah dan gradasi katarak pada pasien katarak dengan diabetes melitus.  Penelitian ini bersifat observasional dengan rancangan cross-sectional dan teknik consecutive sampling dengan subjek sebanyak 44 orang yang terbagi menjadi 4 kelompok berdasarkan kadar HbA1C: (1). HbA1C normal, (2).  HbA1C terkontrol baik (&lt;6,5%), (3). HbA1C terkontrol sedang (6,5-7.9%), dan (4). HbA1C terkontrol buruk (≥8%); dan 3 kelompok berdasarkan gradasi katarak. Hasil uji Kruskal-Wallis menunjukkan perbedaan signifikan (p &lt; 0,05) rerata ROS pada masing-masing kelompok HbA1C. Kemudian dari hasil uji lanjut Mann-Whitney, tidak didapatkan perbedaan signifikan antara kelompok 1 dengan kelompok 2, 3, dan 4; terdapat perbedaan signifikan antara kelompok 2 dengan 3 dan 4; dan tidak didapatkan perbedaan signifikan antara kelompok 3 dan 4. Hasil uji korelasi Spearman menunjukkan terdapat hubungan negatif yang tidak signifikan antara kadar HbA1C dengan ROS pada kelompok 1 (p = 0,958, r = -0,016) dan pada kelompok 4 (p = 0,163, r = -0,477); hubungan negatif yang signifikan pada kelompok 2 (p = 0,04, r = -0,817); dan hubungan positif yang tidak signifikan pada kelompok 3 (p = 0,518, r = 0,232). Hasil uji Kruskal-Wallis menunjukkan perbedaan yang tidak signifikan (p &gt; 0,05) rerata kadar ROS pada kelompok gradasi katarak II, III, dan IV. HbA1C dapat digunakan sebagai salah satu penanda peningkatan ROS pada pasien katarak diabetika, dimana tingginya kadar ROS diperkirakan akan menyebabkan peningkatan progresifitas katarak. 
Prevalensi Dan Karakteristik Penderita Katarak Senilis Di Desa Mendalanwangi, Sidorahayu, Dan Cepokomulyo Di Kabupaten Malang Jawa Timur Nina Handayani; Hendrian Dyatmiko; Seskoati Prayitnaningsih; Sri Andarini
Journals of Ners Community Vol 13 No 1 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i1.2580

Abstract

To study the prevalence and characteristics of age related cataract in an adult population in Malang East Java. A population based, cross sectional study of 692 adults (aged > 50 years) were selected from September until December 2019 from Smarthealth Database. The presence of lens opacity was examined by slit lamp biomicroscopy and evaluated according to Lens Opacity Classification System III. The subtype of cataract present, including nuclear, cortical, and posterior subcapsular, were identified from univariate and 95% confidence interval (CI) for association of each specific type of cataract with age, health examination and medical history. A total of 692 patients with aged > 50 years old were included in this study. The prevalence of cataract was 48,7% in participants over 50 years old. From 337 respondents were in the age range 50-70 years, as many as 240 people (71,22%) patients were female, as many as 206 people (61,13%) patients with primary school education, and 151 people (44,8%) patients work as housewife. The standardized prevalences of clinically significant nuclear, cortical, and posterior subcapsular cataract (PSC) were 7,42%, 7.72%, and 5.34% in an adult population in Mendalanwangi, Sidorahayu and Cepokomulyo village in Malang districs. The prevalence of nuclear, cortical and posterior subcapsular cataract increased high prevalence of age related cataract in the adult population remains a severe public health problem.
Prevalensi Dan Karakteristik Penderita Katarak Senilis Di Desa Mendalanwangi, Sidorahayu, Dan Cepokomulyo Di Kabupaten Malang Jawa Timur Nina Handayani; Hendrian Dyatmiko; Seskoati Prayitnaningsih; Sri Andarini
Journals of Ners Community Vol 13 No 1 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i1.2754

Abstract

To study the prevalence and characteristics of age related cataract in an adult population in Malang East Java. A population based, cross sectional study of 692 adults (aged > 50 years) were selected from September until December 2019 from Smarthealth Database. The presence of lens opacity was examined by slit lamp biomicroscopy and evaluated according to Lens Opacity Classification System III. The subtype of cataract present, including nuclear, cortical, and posterior subcapsular, were identified from univariate and 95% confidence interval (CI) for association of each specific type of cataract with age, health examination and medical history. A total of 692 patients with aged > 50 years old were included in this study. The prevalence of cataract was 48,7% in participants over 50 years old. From 337 respondents were in the age range 50-70 years, as many as 240 people (71,22%) patients were female, as many as 206 people (61,13%) patients with primary school education, and 151 people (44,8%) patients work as housewife. The standardized prevalences of clinically significant nuclear, cortical, and posterior subcapsular cataract (PSC) were 7,42%, 7.72%, and 5.34% in an adult population in Mendalanwangi, Sidorahayu and Cepokomulyo village in Malang districs. The prevalence of nuclear, cortical and posterior subcapsular cataract increased high prevalence of age related cataract in the adult population remains a severe public health problem.
Prevalensi Dan Karakteristik Penderita Katarak Senilis Di Desa Mendalanwangi, Sidorahayu, Dan Cepokomulyo Di Kabupaten Malang Jawa Timur Handayani, Nina; Dyatmiko, Hendrian; Prayitnaningsih, Seskoati; Andarini, Sri
Journals of Ners Community Vol 14 No 1 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i1.2754

Abstract

To study the prevalence and characteristics of age related cataract in an adult population in Malang East Java. A population based, cross sectional study of 692 adults (aged > 50 years) were selected from September until December 2019 from Smarthealth Database. The presence of lens opacity was examined by slit lamp biomicroscopy and evaluated according to Lens Opacity Classification System III. The subtype of cataract present, including nuclear, cortical, and posterior subcapsular, were identified from univariate and 95% confidence interval (CI) for association of each specific type of cataract with age, health examination and medical history. A total of 692 patients with aged > 50 years old were included in this study. The prevalence of cataract was 48,7% in participants over 50 years old. From 337 respondents were in the age range 50-70 years, as many as 240 people (71,22%) patients were female, as many as 206 people (61,13%) patients with primary school education, and 151 people (44,8%) patients work as housewife. The standardized prevalences of clinically significant nuclear, cortical, and posterior subcapsular cataract (PSC) were 7,42%, 7.72%, and 5.34% in an adult population in Mendalanwangi, Sidorahayu and Cepokomulyo village in Malang districs. The prevalence of nuclear, cortical and posterior subcapsular cataract increased high prevalence of age related cataract in the adult population remains a severe public health problem.
THE ASSOCIATION BETWEEN THE COMPONENTS OF METABOLIC SYNDROME AND SENILE CATARACT IN MALANG REGENCY T. Putra, Hartawan; Handayani, Nina
Jurnal Kesehatan Tambusai Vol. 6 No. 3 (2025): SEPTEMBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i3.47867

Abstract

Katarak didefinisikan sebagai kekeruhan lensa kristalina yang merupakan penyebab utama kebutaan. Patofisiologi katarak pada sindrom metabolik (MetS) dapat disebabkan oleh 3 patomekanisme, yaitu stres oksidatif, ketidakseimbangan osmotik, dan glikasi protein non-enzimatik. Pada penelitian ini, kami menyelidiki hubungan antara risiko katarak dengan komponen MetS pada populasi 3 desa di Kabupaten Malang. Penelitian ini merupakan penelitian berbasis populasi cross-sectional retrospektif. Penelitian ini merupakan studi populasi yang dilakukan di 3 desa di Kecamatan Kepanjen, Kabupaten Malang, yaitu Desa Mendalanwangi, Sidorahayu, dan Cepokomuylo. Uji korelasi Spearman digunakan untuk mengetahui hubungan antara MetS dengan kejadian katarak (data ordinal), sedangkan uji regresi logistik digunakan untuk mengetahui pengaruh yang paling dominan. Sebanyak 337 subjek dari 692 populasi yang memenuhi kriteria inklusi dan eksklusi dimasukkan sebagai subjek penelitian. Uji variabel BMI menunjukkan nilai p=0,043 dengan OR=0,827. Uji variabel hipertensi menunjukkan nilai p=0,766 dengan OR=0,952. Hasil uji variabel GDP memiliki nilai p=0,294 dengan OR=0,798. Uji variabel HDL menunjukkan nilai p=0,613 dengan OR=1,092. Terakhir, uji variabel trigliserida menunjukkan nilai p sebesar 0,022 dengan OR sebesar 1,462. Terdapat hubungan yang signifikan antara BMI dan kadar trigliserida dengan kejadian katarak, dimana kadar trigliserida memiliki pengaruh yang lebih signifikan dibandingkan BMI dalam meningkatkan kejadian katarak. Tidak terdapat hubungan yang signifikan antara tekanan darah, kadar gula darah puasa, dan kadar kolesterol HDL dengan kejadian katarak.
Prevalensi Dan Karakteristik Penderita Katarak Senilis Di Desa Mendalanwangi, Sidorahayu, Dan Cepokomulyo Di Kabupaten Malang Jawa Timur Handayani, Nina; Dyatmiko, Hendrian; Prayitnaningsih, Seskoati; Andarini, Sri
Journals of Ners Community Vol 14 No 1 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i1.2754

Abstract

To study the prevalence and characteristics of age related cataract in an adult population in Malang East Java. A population based, cross sectional study of 692 adults (aged > 50 years) were selected from September until December 2019 from Smarthealth Database. The presence of lens opacity was examined by slit lamp biomicroscopy and evaluated according to Lens Opacity Classification System III. The subtype of cataract present, including nuclear, cortical, and posterior subcapsular, were identified from univariate and 95% confidence interval (CI) for association of each specific type of cataract with age, health examination and medical history. A total of 692 patients with aged > 50 years old were included in this study. The prevalence of cataract was 48,7% in participants over 50 years old. From 337 respondents were in the age range 50-70 years, as many as 240 people (71,22%) patients were female, as many as 206 people (61,13%) patients with primary school education, and 151 people (44,8%) patients work as housewife. The standardized prevalences of clinically significant nuclear, cortical, and posterior subcapsular cataract (PSC) were 7,42%, 7.72%, and 5.34% in an adult population in Mendalanwangi, Sidorahayu and Cepokomulyo village in Malang districs. The prevalence of nuclear, cortical and posterior subcapsular cataract increased high prevalence of age related cataract in the adult population remains a severe public health problem.
CENTRAL CORNEAL THICKNESS IN METABOLIC SYNDROME POPULATION, NON-METABOLIC SYNDROME POPULATION, AND DIFFERENT BODY MASS INDEX POPULATION KHULUQI, ROFA HUSNUL; Handayani, Nina; Anandita, Nanda Wahyu
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/d5c5ng91

Abstract

Introduction & ObjectivesCentral corneal Thickness (CCT) is associated with many factors including systemic disease. Thisstudy aims to evaluate and compare the CCT values in Metabolic Syndrome (MS) population, Non-Metabolic Syndrome (non-MS) population, and all different Body Mass Index (BMI) population. MethodsThis population-based & community service-based cross sectional study, conducted on September-November 2019 in 3 rural areas of Malang. Written informed consent was obtained from all subjects.CCT was measured with ultrasound pachymeter. The diagnosis of MS was based on InternationalDiabetes Foundation 2006 criteria. Subjects were classified into 2 groups by MS and non-MS, alsostratifed by BMI, gender, and age. Differences in CCT value between groups based on MS & non-MS, BMI, age, and gender were analyzed. ResultsA total of 890 subjects aged ? 40 years old were included in this study, whereas 400 subjects werediagnosed as MS (44.9%) and 490 (55.1%) others as non-MS. Mean CCT of MS were significantlygreater than that of non-MS (549.743±43.22 ?m, P<0.05). Mean CCT of obese subjects weresignificantly greatest among other BMI groups (549.036±48.31 ?m, P<0.05). Mean CCT in womenwere significantly greater than that in men (546.268±39, P<0.05). Mean CCT of subjects aged 40–49years were significantly greatest among other age groups (551.278±33,33, P<0.05). ConclusionMS population had greater CCT value as compare to non-MS population. Obese population hadgreatest CCT value than overweight, normal, and underweight population. These findings may haveimplications for understanding the relationship between CCT changes and metabolic syndrome, aswell as BMI.
Legalitas Perkawinan Akibat Kehamilan di Luar Nikah Serta Implikasinya Terhadap Status Anak Handayani, Nina; Novita Eka Wardhani; Nayla Oktri Ramadhani; Afrilia Era Vazira; Citra Bethari Ratih; Baidhowi
Jurnal Kajian Islam dan Sosial Keagamaan Vol. 3 No. 2 (2025): Oktober - Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pregnancy outside of marriage is a social phenomenon that raises legal, moral, and religious issues. From an Islamic legal perspective, pregnancy resulting from adultery is considered a major sin, but Islam still provides room for repentance and protection of dignity for women who experience it. In Indonesia, cases of pregnancy outside of marriage are often resolved through marriage, but the legal status of such marriages and the status of the children born from them often cause debate. This study applies a normative-descriptive method with a literature review approach that refers to laws and regulations, fatwas (religious edicts) issued by Islamic scholars, Constitutional Court decisions, and various relevant academic studies. The results of the study show that according to Islamic law, women who become pregnant outside of marriage still have the right to marry, either to the man who impregnated them or to another party who is willing to take responsibility. However, the child's lineage remains with the mother. In the Indonesian positive legal system, Article 43 paragraph (1) of Law Number 1 of 1974, reinforced by Constitutional Court Decision Number 46/PUU-VIII/2010, stipulates that children born outside of marriage have a civil relationship with their mother and biological father, provided that the relationship can be proven through scientific means. Thus, both Islamic law and national law emphasize the importance of protecting women and children born out of wedlock through legal means.