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Poltekkes Kemenkes Semarang
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Profil Hasil Pemeriksaan Dahak Pada Pasien Multidrug-Resistant Tuberculosis (MDR-TB) Alisa Khodrun Nadza; Surati Surati
Jaringan Laboratorium Medis Vol 4 No 2 (2022): November 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i2.8526

Abstract

TB patients who do not adhere to OAT treatment can lead to resistance and become MDR-TB and add to the burden of TB management globally. TB control programs including microscopic sputum examination are important for diagnosis, evaluation, follow-up treatment, and follow-up. The results of the sputum examination used the IUATLD scale as an interpretation of the results and the reporting was negative, scanty, positive one, positive two, and positive three according to the number of TB germs found. The results of the sputum examination to determine the classification of the patient, the decision to start treatment, and the patient's recovery. At the step of treatment for MDR-TB patients, the results of sputum examination are an indicator to determine the success rate of treatment which is marked by the conversion of BTA. Research objectives is to determine the description of the results of sputum examination in Multidrug-Resistant Tuberculosis (MDR-TB) patients at the Kendal District Health Center. Research methods is observational research with descriptive research criteria through a cross sectional approach. Respondents of the study were multidrug-resistant tuberculosis (MDR-TB) patients from three health centers in Kendal district with the highest case prevalence. The study respondents were 7 MDR-TB patients. All study respondents, totaling 7 MDR-TB patients (100%), were included in the advanced step of treatment and showed negative sputum examination results. All study respondents (100%) showed that the results of microscopic sputum examination were negative, which means that BTA conversion occurred at the advanced treatment step.
Perbandingan Persentase Risiko Meninggal pada Pasien Covid-19 Komorbid TBC dengan Komorbid Lainnya di Kabupaten Pati Randi Eka Istananta; Teguh Budiharjo; Surati Surati
Jaringan Laboratorium Medis Vol 5 No 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.9829

Abstract

Corona Virus Disease 2019 (COVID-19) is a disease that has never previously been found in humans and is a new type of disease. The virus that causes COVID-19 is called Sars-CoV-2. It was found that patients experienced increased mortality due to COVID-19 because they had comorbid diseases. COVID-19 patients who have one comorbid disease are at risk of death up to 6.5 times higher than COVID-19 patients without comorbidities. Pulmonary TB is a comorbidity that can make a person more susceptible to contracting COVID-19 with severe symptoms. Apart from attacking the lungs, COVID-19 also damages the lungs. Damaged lungs prevent the body's organs from getting enough oxygen, which can trigger organ damage that can cause death. The aim of this study was to compare the percentage risk of death in COVID-19 patients who had comorbid TB disease with COVID-19 patients who had comorbid kidney disease and DM in the Pati area, Central Java. This research can be a reference for data regarding the percentage risk of death in COVID-19 patients with comorbidities. This research uses a descriptive, observational research design. The samples in this study were COVID-19 sufferers who had comorbid TB, comorbid kidney disease and comorbid DM. The sample population during the period January to December 2021 was 998. The sample was determined using the Slovin formula with a total of 135 samples with a sampling quota taken. Results Comorbid TB has a percentage risk of death of 40%, comorbid kidney has a percentage risk of death of 33.3%, and comorbid DM has a percentage risk of death of 6.8%. Comorbid TB is a comorbid that has the highest percentage risk of death, so intensive care is important for sufferers.
Profil SGOT, SGPT, dan Kreatinin Pada Pasien MDR TB di RS KRMT Wongsonegoro Semarang Surati Surati; Afifah Khairunnisa; Yoki Setyaji; Mochamad Rizal Maulana
Jaringan Laboratorium Medis Vol 6 No 1 (2024): May 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v6i1.10951

Abstract

Tuberculosis (TB) is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis. Tuberculosis apabila is not treated immediately or the treatment is not complete can result in complications leading to death. Multidrugs resistant tuberculosis (MDR-TB) is one of the complications where the germ Mycobacterium tuberculosis can no longer bekilled with several Anti-Tuberculosis Drugs (OAT). The prevalence of MDR-TB cases in Semarang City has increased from 35 cases in 2017 to 79 cases in 2018. MDR-TB therapy takes a longer time, which is about 18-24 months. Prolonged exposure to drugs can affect body functions, especially the kidneys and liver organs which play a role in the process of removing toxins and metabolic waste. This study aims to determine the health profile of the kidney and liver organs of MDR TB sufferers through the SGOT SGPT and Creatinine parameters and describe them based on age and age range. This research is adescriptive quantitative research with a cross-sectional approach. Sampling using total samples of 18 patients. The results showed that 33% (n= 6) of patients had increased levels of SGOT and SGPT, while examination of creatinine levels showed that 33% of patients had kidney problems. Men have upnormal SGOT and SGPT levels of 40% ( n=4) compared to women, which is 25% (n=2), while upnormal creatinine levels in men are 40% (n=4) while in women it is 50% (n = 8). Patients over the age of 46 years have the most levels of SGOT SGPT and upnormal creatinine, which is 61% (n=4). The results showed that age and gender had an effect on increasing SGOT SGPT and Creatinine levels in MDR-TB patients.
Co-Authors Afifah Khairunnisa Alisa Khodrun Nadza Djoko Priyatno Djoko Priyatno Lilik Setyowatiningsih Maulana, Mochamad Rizal Nurul Qomariah Nurul Qomariyah Qurrotu A'yuni Auliya Randi Eka Istananta Ririh Jatmi Wikandari SY Didik Widiyanto SY. Didik Widiyanto Teguh Budiharjo Teguh Budiharjo Teguh Budiharjo Widodo Widodo Yoki Setyaji